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Acta Dermatovenerologica Alpina, Panonica, et Adriatica

Rui Pedro Santos, Sofia Carvalho, Gomes Joana, Joana Perdal
Pseudomyogenic hemangioendothelioma (PHE) is a rare indolent vascular tumor that typically has a multifocal presentation and involves multiple tissue planes. This report describes a 34-year-old man with multiple infiltrated brown papules and plaques on his left leg that had evolved for 6 months. The skin biopsy revealed a dermal and subcutaneous neoplasm composed of fascicles of spindle cells with atypia and epithelioid cells with prominent nucleoli and abundant eosinophilic cytoplasm. There was no evidence of necrosis, and the mitotic rate was low...
December 2018: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Suzana Ljubojević Hadžavdić, Jelena Krtanjek, Paola Đurinec, Lidija Žele-Starčević, Mihael Skerlev, Igor Bartenjev
Lichen sclerosus (LS) is a chronic, inflammatory, mucocutaneous disorder of the genital and extragenital skin. Anogenital warts are benign proliferative lesions caused by human papillomavirus (HPV), which is found in > 95% of lesions. We present two cases of the coexistence of LS and genital warts: one patient with and one without a previous history of genital warts. According to our knowledge and a literature search, only a few cases of the coexistence of LS and genital warts have been reported.
December 2018: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Agnieszka Owczarczyk-Saczonek, Aleksandra Znajewska-Pander, Witold Owczarek, Agata Maciejewska-Radomska, Waldemar Placek
Annular pustular psoriasis (APP) is a rare form of pustular psoriasis with a chronic relapsing course and a good prognosis. The clinical picture is characterized by erythematous lesions, usually polycyclic, with the presence of small, sterile pustules on the circumference of the lesions and fine peeling. We present two cases of APP with diagnostic problems: a 65-year-old woman that suffered from intermittent APP with remission and exacerbation for many years, and an 83-year-old man with lesions that developed after atenolol treatment...
December 2018: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Melike Kibar Ozturk, İlkin Zindanci, Ebru Zemheri, Cumhur Çakır
Epidermoid vulvar cystic lesions are proliferations of epidermal cells that can occur as a complication of female genital mutilation (FGM), which is still a common practice in many cultures, especially in Africa. A 36-year-old Sudanese woman presented with an enlarged clitoral mass that had first appeared 2 years earlier. Her medical history showed that she had undergone FGM when she was 3 years old. A perineal examination revealed a mobile, nontender, rounded cystic swelling with vitiligo lesions. After the cyst was excised, it revealed a 13 ×11 × 11 cm unilocular round mass...
December 2018: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Ana Cristina da Silva Sousa, Rita Venina Amaral Pereira Guedes, Nuno Miguel Bouças Vasconcelos Noronha Menezes, Antónia Maria Cruz Furtado, Armando Manuel Baptista
This case study describes a 37-year-old Caucasian male with pruritic papules and plaques-some with central erosion-on the arms, neck, and trunk that appeared after chemotherapy with FOLFOX (folinic acid, fluorouacil, and oxiliplatin) for colon cancer. A histological examination showed features of neutrophilic eccrine hidradenitis. To the best of our knowledge, this is the first reported case of neutrophilic eccrine hidradenitis due to FOLFOX.
December 2018: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Giuseppe Mancuso
Thiocolchicoside is a muscle relaxant, anti-inflammatory, and analgesic. Administered orally, intramuscularly, or topically, this drug is used in the symptomatic treatment of muscular spasms and rheumatologic disorders. Despite its extensive use, thiocolchicoside is a very rare sensitizer. The case reported here is one of simultaneous contact urticaria and a delayed-type contact allergy to thiocolchicoside. The diagnosis was suggested by the patient's history and demonstrated by immediate and delayed positive skin test responses...
December 2018: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Anja Šterbenc, Polona J. Maver, Mario Poljak
Prophylactic human papillomavirus (HPV) vaccines represent a revolutionary approach in preventing and potentially eliminating HPV-related cancers. Overwhelming real-life data are confirming the high efficacy and exceptional safety profile of all three prophylactic HPV vaccines currently available, which was previously shown in pivotal clinical trials. In this review, we summarized and discussed in our opinion the most influential peer-reviewed literature published between September 2017 and September 2018; that is, during the 2017/2018 school year in Slovenia...
December 2018: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Brittany Urso, Karen B Lu, Amor Khachemoune
Many dermatologic conditions affect the axillae; however, identification is often difficult due to similar clinical presentations. The axillae are unique due to their increased humidity, as well as their high density of hair follicles and sweat glands. Furthermore, they are a site of increased friction due to the presence of closely opposing skin surfaces. In addition to the axillae being involved with common skin diseases affecting other body surface areas, these unique factors also predispose the axillae to less common skin manifestations...
December 2018: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Eugene Klimov, Artemii Tretiakov, Olga Rudko, Anna Soboleva, Ivan Danilin, Irina Korsunskaya, Vladimir Sobolev
This article describes premises for the development of psychodermatology. An analysis of research literature and data is presented based on the example of psoriasis and anxiety disorder. Protein molecules with altered concentrations in patients with psoriasis and anxiety disorder compared to controls are identified (chemokine [C-C motif] ligand 2, corticotropin-release hormone, growth hormone 1, leptin, and tumor necrosis factor with increased concentration and brain-derived neurotrophic factor with decreased concentration)...
December 2018: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Mohammed El Amine Ghembaza, Ali Lounici
INTRODUCTION: This study compares the clinical characteristics and treatment modalities of Behçet's disease patients by age of onset at the Dr. Tidjani Damerdji University Hospital Center in Tlemcen, Algeria. METHODS: Data from patients treated for Behçet's disease between January 1990 and December 2016 were analyzed retrospectively. All patients that fulfilled the diagnostic criteria laid down by the International Study Group for Behçet's Disease were included in the study...
December 2018: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Tasleem Arif, Mohammad Adil, Jaswinder Singh Sodhi, Iffat Hassan
INTRODUCTION: Systemic sclerosis (SSc) is a multisystem connective tissue disease characterized by immune-mediated activation of tissue fibroblasts and consequent fibrosis, vascular abnormalities, and inflammation. The skin and esophagus are the two most frequently involved organs in this disease. Data regarding the correlation between the severity of skin and esophageal involvement in SSc by objective measures are negligible so far. METHODS: Thirty-one patients with SSc were subjected to esophageal manometry...
December 2018: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Maša Vidič, Igor Bartenjev
Among several skin fillers developed in recent decades, hyaluronic acid (HA) fillers have become the material of choice. They are safe, long-lasting, not immunogenic, and cost effective, and they can be removed with hyaluronidase. Unfortunately, early and delayed complications can also occur following HA filler injection. Here we report the case of a hyaluronic filler-related complication in a 50-year-old female patient. The locations affected were the forehead, glabella, and nose. Three days after HA filler application in the upper lip, glabellar region, and nasal root, with no immediate diverse reaction at the time of application, an erythematous, livedoid rash with a well-defined border occurred at the site of the injection in the glabellar region, including the area from the nasal root to the scalp and left upper eyelid...
September 2018: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Pavel Skok, Kristjan Skok
Crohn's disease is a chronic inflammatory bowel disease. The disease is characterized by acute exacerbations with diarrhea, abdominal pain, fever, anorexia, intestinal bleeding, and weight loss. Immune-mediated diseases that are frequently associated with Crohn's disease include arthritis, ankylosing spondylitis, sacroiliitis, episcleritis, uveitis, and skin lesions, such as erythema nodosum and pyoderma gangrenosum. The authors present the case of a 22-year-old female patient that was admitted to their hospital due to diarrhea, fever, arthralgias, and diffuse erythematous papules and plaques with vesicles and pustules affecting the patient's face, lips, arms, trunk, and legs...
September 2018: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Miguel Costa-Silva, Artur César, Preto Gomes Nuno, Filomena Azavedo
Mycobacterium abscessus (M. abscessus) is a non-tuberculous mycobacterium widely present in the natural environment and is now being increasingly identified as a cause of human disease. However, it can cause skin and soft tissue infection following trauma or surgery. We report a case of a skin ulcer associated with M. abscessus in a spa worker. Frequently, contamination with atypical mycobacteria occurs through tap water. However, in most outbreaks the infection source remains unknown. For an early diagnosis, it is important to perform biopsies and mycobacterium cultures...
September 2018: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Anja Blejc Novak, Živa Zupančič, Domen Plut, Diana Gvardijančič, Matjaž Homan
Trichobezoars are gastric foreign bodies rarely found in children. They are mainly composed of swallowed hair. Rapunzel syndrome is a very rare form of trichobezoar characterized by extension of the ingested hair from the stomach into the small intestine or even beyond. Clinical presentation can range from an asymptomatic abdominal mass to severe symptoms: gastric outlet obstruction, perforation of the stomach, and acute pancreatitis. Trichobezoars are usually treated with surgical removal. Here we present the case of an 8-year-old girl in whom a firm non-tender mass in the epigastric region was palpated during a regular outpatient clinic visit...
September 2018: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Funda Tamer, Fatma Gülru Erdoğan, Didem Dinçer Rota, Dilsun Yıldırım
Behçet's disease is a rare disorder of unknown etiology that is classified as a systemic vasculitis. The prevalence of the disease is high in countries in the Far East, Mediterranean Basin, and East Asia. Thus, it is also known as the Silk Road Disease. Behçet's disease is characterized by recurrent oral aphthous ulcers, genital sores, and ocular lesions. However, it can present with severe clinical manifestations as a result of cardiovascular system, central nervous system, and gastrointestinal tract involvement...
September 2018: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Manoj Pawar, Mehak Singh
Sparfloxacin is an antibiotic in the quinolone group of antibacterial agents, which often induce photosensitive skin reactions, more often phototoxic reactions than photoallergic ones, and sometimes associated photo-onycholysis. We present a case of phototoxic dermatitis with photo-onycholysis in a 38-year-old man probably induced by sparfloxacin, which was prescribed to him along with rifampicin and clofazimine because he was suffering from borderline lepromatous leprosy. He developed exaggerated sunburn-like eruptions mainly on sun-exposed sites along with painful onycholysis of the fingernails...
September 2018: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Uwe Wollina
Livedoid vasculopathy is a rare disease related to a hypercoagulable state. It can lead to painful and chronic relapsing ulcerations. We report dermoscopic findings of early, non-ulcerated livedoid vasculopathy in five patients. A mixture of ivory-white atrophic areas with multiple erythematous papules in the center of the lesions is characteristic. With dermoscopy, these papules correspond to glomerular vessels. In the periphery of the lesions some telangiectatic linear vessels complete the picture, although they could be absent in some patients...
September 2018: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Nina Kmet Lunaček, Mario Poljak, Mojca Matičič
With an estimated 15 million infected persons in Europe, hepatitis B virus (HBV) infection is still one of the leading causes of chronic liver disease and associated mortality. The HBV infection prevalence in the general population depends on the region and ranges from 0.01% in Scandinavia to 10.3% in Kyrgyzstan. The prevalence of the 10 HBV genotypes (A-J) varies among different parts of the world, with genotypes A and D being most prevalent in Europe. Other HBV genotypes are mainly imported into Europe from other parts of the world and are rarely detected...
September 2018: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Sabrina Lichon, Amor Khachemoune
Lipomas are the most common soft tissue tumors of mesenchymal origin. They can appear anywhere on the body, and in rare cases they may present on the hands. Lipomas represent approximately 1% to 3.8% of all benign tumors in the hands. Typically, lipomas present in the fifth or sixth decade of life, occurring in both men and women. Lipomas may appear anywhere on the hand, often presenting as painless, slow-growing, and mobile masses. Symptoms may develop if local neurovascular structures are compressed. Differential diagnosis includes liposarcoma and fibrolipomatous hamartoma...
September 2018: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
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