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Acta Dermatovenerologica Alpina, Panonica, et Adriatica

Sofia Lopes, Nuno Gomes, Eunice Trindade, Filomena Azevedo, Sofia Magina
Hidradenitis suppurativa (HS) is a chronic and recurrent inflammatory disease characterized by the presence of painful and deep inflammatory lesions usually located in intertriginous areas. It rarely occurs in children, especially in prepubertal age. Treatment for HS in this age group is challenging considering the scant data available and the risk of adverse effects in younger patients. We report the case of a 10-year-old girl with Hurley III HS, refractory to multiple topical and systemic therapies. After introducing adalimumab, there was significant improvement of the skin lesions and therefore in the child's quality of life...
September 2019: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Zofia Nevozinskaya, Iryna Korsunskaya, Luiza Sakaniya, Yury Perlamutrov, Vladimir Sobolev
Peutz-Jeghers syndrome is a rare autosomal dominant disorder. Approximately 1:25,000 to 1:280,000 cases are registered annually. The pathogenesis of the disease is based on the mutation of the STK 11 gene on chromosome 19. Peutz-Jeghers syndrome is characterized by several symptoms: the formation of multiple hamartomatous polyps primarily in the gastrointestinal tract and hyperpigmentation of the mucous membranes and skin. Patients with Peutz-Jeghers syndrome often develop various malignant neoplasms, mainly localized in the pancreas and colon...
September 2019: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Georgia Kyriakou, Maria Gkermpesi, Konstantinos Thomopoulos, Markos Marangos, Sophia Georgiou
Crohn's disease (CD) is a multi-systemic chronic granulomatous inflammatory disease with a constellation of extraintestinal manifestations affecting various organs, including the skin. Metastatic CD (MCD), defined as granulomatous lesions of the skin occurring at sites separate from the gastrointestinal (GI) tract in patients affected with CD, is the least common cutaneous manifestation, and it is occasionally the primary manifestation of the disease. It may precede any symptoms from the GI tract by months or even years, and it often remains undiagnosed...
September 2019: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Hossein Kavoussi, Reza Kavoussi
Revision of a depressed scar is more challenging because it does not follow the relaxed skin tension line (RSTL). Several measures have been suggested for revision of this type of scar, and they have a number of limitations, complications, advantages, and disadvantages. A 45-year-old woman presented with a depressed scar measuring approximately 45 × 2.5 mm across the chin area as a result of an accidental sharp trauma 17 years previously. She was subjected to several procedures to revise the scar, but none of them were satisfactory...
September 2019: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Nicolas Kluger
INTRODUCTION: It is not known whether tattoo-related complications are becoming more frequent and, if so, how quickly. METHODS: Data generated through Google Trends (GT) worldwide, from January 1st, 2004 to December 31st, 2018, were analyzed for the search volume indexes (SVIs) of selected symptoms ("swollen tattoo," "raised tattoo," "tattoo bumps," "itchy tattoo," "tattoo fading"), diagnosis ("infected tattoo," "tattoo allergy"), and control terms ("tattoo care," "tattoo healing")...
September 2019: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Ligi Isac, Song Jiquan
Psoriasis is a chronic inflammatory T cell-mediated immunological disease. It is found to be associated with an increased expression of T-helper 1 and T-helper 17 lymphocytes and decreased expression of T-helper 2 and T-regulatory lymphocytes. Interleukin 10 (IL-10) is an important immunosuppressive cytokine mainly produced by T-helper 2 and T regulatory cells. The main function of IL-10 is to terminate and control inflammatory processes and thereby maintain an immunological homeostasis. Because of its anti-inflammatory properties, IL-10 is a current focus of interest in research...
September 2019: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Mondana H Ghias, Norhan Shamloul, Amor Khachemoune
Several common practices and widely accepted principles implemented in dermatologic surgery are based on perpetuated beliefs not supported by evidence-based medicine. After evaluating the validity of misconceptions in dermatologic surgery, updated recommendations include restriction of antibiotic prophylaxis to patient-specific risk factors, continuation of anticoagulant therapy perioperatively, safe use of epinephrine for digital anesthesia, clean technique as an efficacious substitute for sterile, topical emollients and petroleum instead of antimicrobials to prevent surgical site infection, alternatives to elliptical excisions for decreasing scar length, wound eversion for areas of greater cosmetic concern, and cessation of systemic retinoids as an unnecessary prerequisite for most cutaneous procedures...
September 2019: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Hersha Patel, Susan M Sherman, Kristine Pčolkina, Kristīne Strazdiņa, Ilze Viberga, Charles W Redman, Jana Zodzika, Dace Rezeberga, Esther L Moss
INTRODUCTION: The incidence of cervical cancer (CC) in eastern European countries is high; however, uptake of available prevention strategies is suboptimal. We explored knowledge, behaviors, and attitudes toward CC prevention strategies in Latvian women. METHODS: A mixed-methods study of Latvian women, consisting of surveys and semi-structured interviews, was conducted in Riga, Latvia in September and October 2015. RESULTS: Altogether, 158 surveys were completed and 10 interviews were conducted...
September 2019: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Rune Kjærsgaard Andersen, Gregor Borut Ernst Jemec
INTRODUCTION: Teledermatology is a useful tool for underserved areas. However, because it is not without costs, knowledge of the burdens incurred by teledermatology treatment would be valuable for future types of management. METHODS: All specialist dermatology services in the Faroe Islands have been provided by our department through a mix of standard and teledermatology consultations. We performed a retrospective review of the teledermatology database from its inauguration in 2003 to November 2018...
September 2019: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Helena Klar, Nika Sotošek, Julij Šelb, Mitja Košnik
BACKGROUND: The aim of the study was to explore the frequency and the clinical and diagnostic characteristics of a single nonsteroidal anti-inflammatory drug-induced hypersensitivity (SNIUAA) subgroup. METHODS: In the hospital information system we identified patients who performed the oral provocation test (OPT) with analgesics between 2004 and 2016. We divided patients into phenotype groups based on clinical history and OPT results. RESULTS: Altogether, 248 patients (44...
September 2019: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
(no author information available yet)
In the original printed version of the case report (1), the order of authors within the author list was incorrect. Shruti S was incorrectly listed as the second author and should have been listed as the first author. The PDF has been corrected accordingly and can be accessed at
June 30, 2019: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Claudio Conforti, Roberta Vezzoni, Anna Moret, Chiara Retrosi, Paola Corneli, Giovanni Magaton-Rizzi, Iris Zalaudek, Nicola di Meo
The Koebner phenomenon is well described and well known in clinical practice. Sometimes it can take on a linear appearance, the diagnosis of which can be facilitated by the use of dermatoscopy. In this case, we present a comparison between a linear Koebner phenomenon on light and dark skin, reporting the salient dermatoscopic characteristics and relating them to histopathology.
June 2019: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Miroslav Nečas, Vladimír Vašků, Eva Březinová
The authors present two cases of severe atopic dermatitis with extremely elevated IgE levels treated with omalizumab. The effect of this treatment was completely unconvincing in both patients, most likely because of extremely elevated IgE values, which could not be eliminated by omalizumab. Our observation is consistent with earlier published literature reporting that omalizumab as a treatment for atopic dermatitis seems to work better in patients with lower levels of IgE antibodies.
June 2019: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Eva Klara Merzel Šabović, Olga Točkova, Tina Uršič, Borut Žgavec, Mateja Dolenc-Voljč
Hand, foot, and mouth disease is a highly contagious disease that predominantly affects children under the age of five. The illness is much less common in adults and often presents with atypical skin lesions. Here we describe the case of a 19-year-old healthy, immunocompetent male patient with atypical clinical presentation, with a macular rash on the scalp, palms, soles, and shins, and with minimal lesions in the oral cavity. The diagnosis of hand, foot, and mouth disease was confirmed by isolation of coxsackievirus A6 from a vesicle smearobtained on the right sole...
June 2019: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Clare A Goggins, Amor Khachemoune
Hyperbaric oxygen therapy (HBOT) is used in the management of a wide array of disease states, including acute thermal burn injuries, carbon monoxide poisoning, and decompression sickness, to name a few. Although HBOT is approved by the Undersea and Hyperbaric Medical Society for the treatment of only 14 conditions, it has been used "off-label" in the management of a variety of dermatological diseases. This review investigates the utilization of HBOT in dermatology and appraises the evidence behind its use...
June 2019: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Pavel V Chernyshov, Iryna Humenna
INTRODUCTION: The human papillomavirus (HPV) vaccination has not yet been integrated into the national immunization program in Ukraine, and the vaccination rate is low. The objectives of our study were to investigate HPV vaccination prevalence and knowledge, risk of HPV transmission, and HPV-related cervical cancer awareness in female medical students. METHODS: Female medical students at Bohomolets National Medical University in their 2nd through 6th years of the program completed an anonymous survey on HPV infection and vaccination...
June 2019: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Majda Troha, Anja Šterbenc, Martina Mlaker, Mario Poljak
INTRODUCTION: Human papillomavirus (HPV) vaccination was included in the national vaccination program in Slovenia in the 2009/2010 school year. It is recommended for girls attending the sixth grade of primary school only and is fully state funded. Based on the initiative of school medicine specialists, Idrija and Cerkno were the first two municipalities to offer municipally sponsored HPV vaccination to boys in the 2014/2015 school year, showing promising results. METHODS: Our aim was to evaluate HPV vaccination coverage among boys attending the sixth grade who received the municipally sponsored HPV vaccine...
June 2019: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Funda Tamer, Mehmet Eren Yuksel, Emine Avcı
INTRODUCTION: Isotretinoin is a commonly used systemic retinoid for treating acne. However, isotretinoin may lead to elevated serum levels of triglycerides and cholesterol, and it may affect liver function tests. Moreover, the effect of isotretinoin on hematological parameters remains controversial. This study examines changes in the blood chemistry panel, hematological parameters, and inflammation biomarkers of patients diagnosed with acne and treated with isotretinoin. METHODS: The study included 70 patients (59 females and 11 males, between ages 18 and 37) with moderate to severe acne vulgaris treated with isotretinoin...
June 2019: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Sofia Lopes, Júlia Vide, Miguel Costa-Silva, Filomena Azevedo, Sofia Magina
INTRODUCTION: Hidradenitis suppurativa (HS) is an unrecognized chronic inflammatory and debilitating disease with severe consequences for patients' quality of life. METHODS: A survey was performed among general practitioner (GP) residents and consultants in order to determine awareness, knowledge, and attitudes about HS. RESULTS: Among 372 respondents, 74% were GP residents in the first 2 years, 22% GP residents in the 3rd and 4th year, and 4% consultants...
June 2019: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Mustafa Tunca, Mehmet Gamsızkan, Aslan Yürekli, Berk Alp Göksel, Ali Ali Fuat Çiçek, Ercan Ercan Çalışkan
BACKGROUND: The rabbit ear hypertrophic scar model is a preferred animal model of excessive scarring for investigating the scarring process and novel treatment modalities. In this model, surgical removal of perichondrium can be challenging, and it is often insufficient or damages the underlying cartilage. It is hypothesized that cryosurgery would offer a more efficient alternative to conventional surgery. The objective of this study was to compare structural changes in scar tissues in two groups of the hypertrophic scar model: cryosurgery compared to standard conventional surgery...
June 2019: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
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