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Journals Colloids and Surfaces. B, Bioi...

Colloids and Surfaces. B, Biointerfaces

https://read.qxmd.com/read/38762934/folic-acid-mediated-enhancement-of-the-diagnostic-potential-of-luminescent-europium-doped-hydroxyapatite-nanocrystals-for-cancer-biomaging
#1
JOURNAL ARTICLE
Gerardo Martin Quindoza, Rui Horimoto, Yasuhiro Nakagawa, Yuta Aida, Vincent Irawan, Jumpei Norimatsu, Hayato Laurence Mizuno, Yasutaka Anraku, Toshiyuki Ikoma
Early and accurate cancer diagnosis is crucial for improving patient survival rates. Luminescent nanoparticles have emerged as a promising tool in fluorescence bioimaging for cancer diagnosis. To enhance diagnostic accuracy, ligands promoting endocytosis into cancer cells are commonly incorporated onto nanoparticle surfaces. Folic acid (FA) is one such ligand, known to specifically bind to folate receptors (FR) overexpressed in various cancer cells such as cervical and ovarian carcinoma. Therefore, surface modification of luminescent nanoparticles with FA can enhance both luminescence efficiency and diagnostic accuracy...
May 16, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38761494/ikvav-functionalized-oriented-pcl-fe-3-o-4-scaffolds-for-magnetically-modulating-drg-growth-behavior
#2
JOURNAL ARTICLE
Yaqiong Liu, Hongxia Gao, Yuqing Shang, Shaolan Sun, Wenchao Guan, Tiantian Zheng, Linliang Wu, Meng Cong, Luzhong Zhang, Guicai Li
The re-bridging of the deficient nerve is the main problem to be solved after the functional impairment of the peripheral nerve. In this study, a directionally aligned polycaprolactone/triiron tetraoxide (PCL/Fe3 O4 ) fiber scaffolds were firstly prepared by electrospinning technique, and further then grafted with IKVAV peptide for regulating DRG growth and axon extension in peripheral nerve regeneration. The results showed that oriented aligned magnetic PCL/Fe3 O4 composite scaffolds were successfully prepared by electrospinning technique and possessed good mechanical properties and magnetic responsiveness...
May 16, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38759294/synergistic-enhancement-mediated-sensitive-sers-based-immunoassay-of-psa-using-versatile-pdms-agnps-zif-67-biomimetic-substrates
#3
JOURNAL ARTICLE
Hengwei Zhao, Zhihan Liu, Shijiao Fu, Tao Jiang, Kerong Wu
Among various biomimetic polymer materials, polydimethylsiloxane (PDMS) stands out as an ideal matrix for surface-enhanced Raman scattering (SERS) due to its unique intrinsic Raman signal and tenacity. In order to realize the precise detection of prostate-specific antigen (PSA), we proposed a sandwich-type SERS-active immunostructure composed of PDMS@silver nanoparticles (Ag NPs)@ZIF-67 biomimetic film as the immunosubstrate and gold nanorods (Au NRs) as immunoprobes. Due to the synergistic effect of electromagnetic enhancement facilitated by biomimetic surfaces and chemical enhancement achieved by ZIF-67, this structure enabled an ultrasensitive and selective detection of PSA across a broad range from 10-3 to 10-9 mg/mL...
May 16, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38761495/evaluating-the-biomolecular-interaction-between-delamanid-formulations-and-human-serum-albumin-by-fluorescence-cd-spectroscopy-and-spr-effects-on-protein-conformation-kinetic-and-thermodynamic-parameters
#4
JOURNAL ARTICLE
Krittawan Tongkanarak, Camille Loupiac, Fabrice Neiers, Odile Chambin, Teerapol Srichana
Delamanid is an anti-tuberculosis drug used for the treatment of drug-resistant tuberculosis. Since delamanid has a high protein bound potential, even patients with low albumin levels should experience high and rapid delamanid clearance. However, the interaction between delamanid and albumin should be better controlled to optimize drug efficacy. This study was designed to evaluate the binding characteristics of delamanid to human serum albumin (HSA) using various methods: fluorescence spectroscopy, circular dichroism (CD), surface plasmon resonance (SPR), and molecular docking simulation...
May 14, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38759296/a-zn-2-cross-linked-sodium-alginate-epigallocatechin-gallate-hydrogel-scaffold-for-promoting-skull-repair
#5
JOURNAL ARTICLE
Huan Jing, Yun Wu, Yuntao Lin, Tingting Luo, Hongsheng Liu, Zhen Luo
The optimal material for repairing skull defects should exhibit outstanding biocompatibility and mechanical properties. Specifically, hydrogel scaffolds that emulate the microenvironment of the native bone extracellular matrix play a vital role in promoting osteoblast adhesion, proliferation, and differentiation, thereby yielding superior outcomes in skull reconstruction. In this study, a composite network hydrogel comprising sodium alginate (SA), epigallocatechin gallate (EGCG), and zinc ions (Zn2+ ) was developed to establish an ideal osteogenic microenvironment for bone regeneration...
May 14, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38749168/an-injectable-bone-paste-of-poly-lactic-acid-zinc-doped-nano-hydroxyapatite-composite-microspheres-for-skull-repair
#6
JOURNAL ARTICLE
Xinrui Du, Xiaoting Yuan, Si Lin, Xinyu Tan, Yingchao Han
In this study, poly (lactic acid)/zinc-doped nano hydroxyapatite (PLA/nano-ZnHA) composite microspheres were prepared and formed into injectable bone paste with sodium alginate (SA) and polyvinyl alcohol (PVA) for bone defect repair. The effect of component of bone paste on injectability and zinc doping content related biological properties were mainly discussed. An injectable bone paste of PLA/nano-ZnHA composite microspheres (CM) was formed in mass ratio of (2.5-25):(0.25-4): (0-2.5):(20-65) of CM, SA, PVA and water with the favorable injectability (average force:4...
May 13, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38749169/enhanced-breast-cancer-treatment-using-phototherapy-and-rns-therapy-with-macrophage-membrane-coated-liposomes
#7
JOURNAL ARTICLE
Feiran Wang, Chenhao Li, Xiaodong Xu, Wei Zhang, Zhixian He
Breast cancer, the predominant malignancy afflicting women, continues to pose formidable challenges despite advancements in therapeutic interventions. This study elucidates the potential of phototherapy, comprising both photothermal and photodynamic therapy (PTT/PDT), as a novel and promising modality. To achieve this goal, we devised liposomes coated with macrophage cell membranes including macrophage-associated membrane proteins, which have demonstrated promise in biomimetic delivery systems for targeting tumors while preserving their inherent tumor-homing capabilities...
May 11, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38749167/the-antibacterial-and-antialgal-enhancement-of-the-hydroquinone-acrylamide-polyurethane-coating-based-on-microphase-separation
#8
JOURNAL ARTICLE
Xu Chang, Shi Xiaohui, Zhang Zhijia, Zhou Wenjun, Zhang Songsong, Wang Guojun, Wang Qiang, Ma Teng, Wang Lin, Wei Hao, Mu Minhao
The undesirable and inevitable adhesion of marine organisms on submerged surfaces has seriously affect the environment, economy and society, so emerging and promising strategies for antifouling are required. Here, the novel and environmental strategy of the antibacterial and antialgal materials was proposed for the application of the antifouling coating without releasing harmful substances. The environment-friendly antifouling agent, the capsaicin derivative N-(2,5-dihydroxy-4-acrylamide meth-ylbenzyl)acrylamide (PHABA), was modified to the molecular chain of the polyurethane...
May 11, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38744080/ros-responsive-carboxymethyl-chitosan-nanoparticles-loaded-with-astaxanthin-for-alleviating-oxidative-damage-in-intestinal-cells
#9
JOURNAL ARTICLE
Xiaoting Yu, Yannan Chen, Mingqian Tan
The controlled release of antioxidant substances at the intestinal oxidative damage site is crucial for alleviating intestine-related diseases. Herein, the novel ROS-responsive carrier was synthesized through simple amidation reaction between carboxymethyl chitosan (CMC) and methionine (Met), a natural organic compound containing ROS-responsive linkages (thioether). Initially, astaxanthin (AXT) nanoparticles (AXT2 @CMT) with excellent stability and drug loading capacity (39.68 ± 0.23 μg/mL) were prepared by optimizing various reaction conditions...
May 10, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38729023/corrigendum-to-the-mechanism-of-self-assembled-mixed-micelles-in-improving-curcumin-oral-absorption-in-vitro-and-in-vivo-%C3%A2-colloids%C3%A2-surf-b-biointerfaces-133-2015-108-119
#10
Jinling Wang, Wenzhuan Ma, Pengfei Tu
No abstract text is available yet for this article.
May 9, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38733647/novel-biomimetic-macromolecules-system-for-highly-efficient-lubrication-ros-scavenging-and-osteoarthritis-treatment
#11
JOURNAL ARTICLE
Xiaoduo Zhao, Lumin Yang, Licheng Zhang, Le Ji, Shuanhong Ma, Feng Zhou
The early stages of osteoarthritis (OA) in the joints are typically characterized by two key factors: the dysfunction of articular cartilage lubrication and inflammation resulting from the excessive production of reactive oxygen species (ROS). Synthetic injectable macromolecular materials present great potential for preventing the progression of early OA. In this study, to mimic the excellent lubricity of brush-like aggregates found in natural synovial fluid, we develop a novel macromolecular biolubricant (CS-PS-DA) by integrating adhesion and hydration groups onto backbone of natural biomacromolecules...
May 8, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38733646/a-novel-treatment-modality-for-rheumatoid-arthritis-inflammation-targeted-multifunctional-metal-organic-frameworks-with-synergistic-phototherapy-and-chemotherapy
#12
JOURNAL ARTICLE
Hejie Zhao, Jun Wei, Yangjingwan He, Yiqun Wu, Liang Ge, Chunli Zheng
Rheumatoid arthritis (RA) is an autoimmune inflammatory disease with complex pathogenesis. Single chemotherapy struggles to eliminate the disease permanently and reduce the pain owing to drug resistance and inadequate delivery to target cells. This study developed hyaluronic acid (HA)-modified and methotrexate (MTX)-load metal-organic frameworks (denoted as FT-HA-MTX NPs), combining photothermal therapy (PTT), photodynamic therapy (PDT), and chemotherapy to inhibit the progression of RA. In vitro experiments proved that the obtained NPs exhibited good biocompatibility and commendable photothermal conversion efficiency of 36...
May 8, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38759295/harnessing-extracellular-vesicle-membrane-for-gene-therapy-evs-biomimetic-nanoparticles
#13
JOURNAL ARTICLE
Erik Briffault, Patricia Garcia-Garcia, Rebeca Martinez-Borrajo, Carmen Evora, Araceli Delgado, Patricia Diaz-Rodriguez
One of the main concerns in oligonucleotide-based therapeutics is achieving a successful cell targeting while avoiding drug degradation and clearance. Nanoparticulated drug delivery systems have emerged as a way of overcoming these issues. Among them, membrane-coated nanoparticles are of increasing relevance mainly due to their enhanced cellular uptake, immune evasion and biocompatibility. In this study, we designed and elaborated a simple and highly tuneable biomimetic drug delivery nanosystem based on a polymeric core surrounded by extracellular vesicles (EVs)-derived membranes...
May 7, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38754200/swelling-kinetics-of-mixtures-of-soybean-phosphatidylcholine-and-glycerol-dioleate
#14
JOURNAL ARTICLE
Jenni Engstedt, René In 't Zandt, Justas Barauskas, Vitaly Kocherbitov
Lipid-based drug delivery systems offer the potential to enhance bioavailability, reduce dosing frequency, and improve patient adherence. In aqueous environment, initially dry lipid depots take up water and form liquid crystalline phases. Variation of lipid composition, depot size and hydration-induced phase transitions will plausibly affect the diffusion in and out of the depot. Lipid depots of soybean phosphatidylcholine (SPC) and glycerol dioleate (GDO) mixtures were hydrated for varying time durations in a phosphate-buffered saline (PBS) buffer and then analyzed with Karl Fischer titration, magnetic resonance imaging (MRI) and gravimetrically...
May 7, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38744078/nucleus-targeted-carbon-dots-as-peroxidase-nanozyme-for-photoacoustic-imaging-and-phototherapy-of-tumor
#15
JOURNAL ARTICLE
Shanshan Liu, Jianfeng Wang, Xuemin Wang, Yimin Guo, Shaokang Guan, Tao Zhang
High-purity carbon dots (CDs) with a highly π-conjugated sp2 -hybridized graphite structure were prepared by the pulse electrolysis method using the graphite plate as raw material. Photoacoustic signal together with photothermal effect was found in the CDs-dispersed suspensions under near-infrared (NIR) irradiation. For the suspension with the CDs concentration of 500 μg/mL, the photothermal conversion efficiency is high up 64.3% and the solution's temperature can be increased to 82.2 °C under NIR irradiation...
May 7, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38744076/ph-responsive-drug-loaded-peptides-enhance-drug-accumulation-and-promote-apoptosis-in-tumor-cells
#16
JOURNAL ARTICLE
Zhongying Gong, Hongxia Zhao, Jingkun Bai
The efficacy of chemotherapeutic drugs in tumor treatment is limited by their toxicity and side effects due to their inability to selectively accumulate in tumor tissue. In addition, chemotherapeutic agents are easily pumped out of tumor cells, resulting in their inadequate accumulation. To overcome these challenges, a drug delivery system utilizing the amphiphilic peptide Pep1 was designed. Pep1 can self-assemble into spherical nanoparticles (PL/Pep1) and encapsulate paclitaxel (PTX) and lapatinib (LAP). PL/Pep1 transformed into nanofibers in an acidic environment, resulting in longer drug retention and higher drug concentrations within tumor cells...
May 7, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38729021/microfluidic-chemistry-assisted-synthesis-of-cobalt-quantum-dot-embedded-nitrogen-doped-carbon-with-oxidase-like-properties-toward-ascorbic-acid-detection
#17
JOURNAL ARTICLE
Jiaqi Chen, Yiqian Su, Weitai Yu, Huiqin Li, Tao Yin, Pengcheng Lin
Ascorbic acid (AA) is a powerful antioxidant in food safety and disease treatment. It is of great significance to develop a low-cost, high-stability, and easy-to-operate colorimetric method for quantitative detection of AA in food or human body. Although various nanozymes have been developed for the colorimetric detection of AA, the size regulation of the catalytic center of nanozymes remains a challenge. In this work, we propose a combined strategy of flow chemistry synthesis and pyrolysis to realize the controllable adjustment of the catalytic center size of nanozymes...
May 7, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38744079/electrostatic-interactions-mediated-defibrillation-of-%C3%AE-lactoglobulin-fibrils-using-keggin-polyoxometalates
#18
JOURNAL ARTICLE
Ritu Zende, Ashim Jyoti Bharati, Mounish Reddy Mannem, Priya Bhatt, Somenath Garai, Santosh Kumar Upadhyay, Kamatchi Sankaranarayanan
The whey protein β-lactoglobulin (βLG) forms fibrils similar to the amyloid fibrils in the neurodegenerative diseases due to its higher predisposition of β-sheets. This study shed light on the understanding different inorganic Keggin polyoxometalates (POMs) interaction with the protein βLG fibrils. POMs such as Phosphomolybdic acid (PMA), silicomolybdic acid (SMA), tungstosilicic acid (TSA), and phosphotungstic acid (PTA) were used due to their inherent higher anionic charges. The interaction studies were monitored with fluorescence spectra and Thioflavin T assay for both the βLG monomers and the fibrils initially to elucidate the binding ability of the POMs...
May 6, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38729022/research-and-application-of-hydrogel-encapsulated-mesenchymal-stem-cells-in-the-treatment-of-myocardial-infarction
#19
REVIEW
Haien Guan, Yuehua Chen, Xuanyu Liu, Li Huang
Myocardial infarction (MI) stands out as a highly lethal disease that poses a significant threat to global health. Worldwide, heart failure resulting from MI remains a leading cause of human mortality. Mesenchymal stem cell (MSC) therapy has emerged as a promising therapeutic approach, leveraging its intrinsic healing properties. Nevertheless, pervasive issues, including a low cell retention rate, suboptimal survival rate, and incomplete differentiation of MSCs, present formidable challenges for further research...
May 6, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38749166/natural-melanin-nanoparticles-mnps-extracted-from-sepia-officinalis-a-cost-effective-chemo-photothermal-synergistic-nanoplatform-for-osteosarcoma-treatment
#20
JOURNAL ARTICLE
Mariana Caldas, Ana I Barbosa, Mrinal Bhattacharya, Rui L Reis, Vitor M Correlo
Osteosarcoma conventional chemotherapeutics are known for their side effects, limited options, and induction of drug resistance. This creates the need to develop new therapeutics capable of effectively destroying cancer cells with low toxicity, improving patient survival rate and their life quality. This work reports a novel drug delivery nanoplataform made of Natural Melanin Nanoparticles (MNPs), obtained from Sepia officinalis ink, with 99% incorporation efficiency of doxorubicin (Dox) without the use of non-toxic solvents...
May 3, 2024: Colloids and Surfaces. B, Biointerfaces
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