journal
Journals Colloids and Surfaces. B, Bioi...

Colloids and Surfaces. B, Biointerfaces

https://read.qxmd.com/read/38522285/emerging-application-of-nanomedicine-based-therapy-in-acute-respiratory-distress-syndrome
#1
REVIEW
Yitianhe Xu, Leyao Lv, Qian Wang, Qing Yao, Longfa Kou, Hailin Zhang
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are serious lung injuries caused by various factors, leading to increased permeability of the alveolar-capillary barrier, reduced stability of the alveoli, inflammatory response, and hypoxemia. Despite several decades of research since ARDS was first formally described in 1967, reliable clinical treatment options are still lacking. Currently, supportive therapy and mechanical ventilation are prioritized, and there is no medication that can be completely effective in clinical treatment...
March 21, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38522284/hawthorn-pectin-soybean-isolate-protein-hydrogel-bead-as-a-promising-ferrous-ion-embedded-delivery-system
#2
JOURNAL ARTICLE
Wenxian Sun, Kaixuan Bu, Huangmei Meng, Chuanhe Zhu
In this study, hydrogel beads [SPI/HP-Fe (II)] were prepared by cross-linking soybean isolate protein (SPI) and hawthorn pectin (HP) with ferrous ions as a backbone, and the effects of ultrasound and Fe2+ concentration on the mechanical properties and the degree of cross-linking of internal molecules were investigated. The results of textural properties and water-holding capacity showed that moderate ultrasonic power and Fe2+ concentration significantly improved the stability and water-holding capacity of the hydrogel beads and enhanced the intermolecular interactions in the system...
March 21, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38520950/lipid-coated-nanocrystals-of-paclitaxel-as-dry-powder-for-inhalation-characterization-in-vitro-performance-and-pharmacokinetic-assessment
#3
JOURNAL ARTICLE
Manish Kumar, Abhishek Jha, Kanchan Bharti, Manjit Manjit, Pradnya Kumbhar, Vividha Dhapte-Pawar, Brahmeshwar Mishra
BACKGROUND: Nanocrystals can be produced as a dry powder for inhalation (DPIs) to deliver high doses of drug to the lungs, owing to their high payload and stability to the shear stress of aerosolization force. Furthermore, lipid-coated nanocrystals can be formulated to improve the drug accumulation and retention in lung. OBJECTIVE: The present work involved the fabrication of paclitaxel nanocrystals using hydrophilic marine biopolymer fucoidan as a stabilizer. Thereafter, fabricated nanocrystals (FPNC) were surface-modified with phospholipid to give lipid-coated nanocrystals (Lipo-NCs)...
March 21, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38522283/interfacial-blending-in-co-axially-electrospun-polymer-core-shell-fibers-and-their-interaction-with-cells-via-focal-adhesion-point-analysis
#4
JOURNAL ARTICLE
Martyna Polak, Daniel P Ura, Krzysztof Berniak, Piotr K Szewczyk, Mateusz M Marzec, Urszula Stachewicz
Electrospun polymer scaffolds have gained prominence in biomedical applications, including tissue engineering, drug delivery, and wound dressings, due to their customizable properties. As the interplay between cells and materials assumes fundamental significance in biomaterials research, understanding the relationship between fiber properties and cell behaviour is imperative. Nevertheless, altering fiber properties introduces complexity by intertwining mechanical and surface chemistry effects, challenging the differentiation of their individual impacts on cell behaviour...
March 20, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38522282/an-antimicrobial-film-of-silver-nanocellulose-crystal-oxalic-acid-polyvinyl-alcohol-with-real-time-bactericidal-and-prevention-of-biofilm-formation-properties
#5
JOURNAL ARTICLE
Hui Li, Xianxiang Zeng, Ting Yao, Hengyi Xu
Silver nanoparticles (AgNPs) is an excellent antibacterial agent, which is widely used in medical, food, environmental and other fields, but AgNPs are easy to accumulate in aqueous solution, so their application in various fields is limited. Therefore, it is particularly important to propose a new application method or to prepare a new composite material. In this study, OA/PVA was obtained by cross-linking oxalic acid (OA) with polyvinyl alcohol (PVA). Then Ag/NCC was obtained by in situ reduction of AgNPs on nanocellulose crystals (NCC)...
March 20, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38520952/inhibition-of-platelet-adhesion-to-exposed-subendothelial-collagen-by-steric-hindrance-with-blocking-peptide-nanoparticles
#6
JOURNAL ARTICLE
Anqi Wang, Kai Yue, Xiaotong Yan, Weishen Zhong, Genpei Zhang, Lei Wang, Hua Zhang, Xinxin Zhang
The inhibition of platelet adhesion to collagen in exposed vessels represents an innovative approach to the treatment of atherosclerosis and thrombosis. This study aimed to engineer peptide-based nanoparticles that prevent platelet binding to subendothelial collagen by engaging with collagen with high affinity. We examined the interactions between integrin α2/ glycoprotein VI/ von Willebrand factor A3 domain and collagen, as well as between the synthesized peptide nanoparticles and collagen, utilizing molecular dynamics simulations and empirical assays...
March 20, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38520951/ucnps-labeled-electrospun-scaffolds-used-to-monitor-in-vivo-degradation-and-bone-tissue-regeneration
#7
JOURNAL ARTICLE
Danfang Sun, Xirao Sun, Dan Li, Meng Wang, Siyu Song, Chang Liu, Nan Ma, Xiumei Yin, Chengyue Wang
Biodegradable electrospun bone repair materials are effective means to treat bone defects. However, because the electrospun substrates are mostly organic polymer materials, there is a lack of real-time and intuitive monitoring methods for their degradation in vivo. Therefore, it is of great significance to develop in vivo traced electrospun bone repair materials for postoperative observation of their degradation. In this research, polycaprolactone/up-conversion nanoparticles/magnesium oxide (PCL/UCNPs/MgO) composite scaffolds were prepared by electrospun based on the luminescence characteristics of up-conversion nanoparticles (UCNPs) under near infrared excitation and the osteogenic ability of MgO...
March 20, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38518556/clozapine-laden-carbon-dots-delivered-to-the-brain-via-an-intranasal-pathway-synthesis-characterization-ex-vivo-and-in-vivo-studies
#8
JOURNAL ARTICLE
Hetal P Patel, Priya H Desai, Rikin V Patel, Sandesh N Lodha, Anil H Gore, Pravin O Patil, Bhargavi V Desai, Ditixa T Desai, Bhavin A Vyas, Mark D P Willcox, Furqan A Maulvi
Clozapine, which is widely used to treat schizophrenia, shows low bioavailability due to poor solubility and high first-pass metabolism. The study aimed to design clozapine-loaded carbon dots (CDs) to enhance availability of the clozapine to the brain via intranasal pathway. The CDs were synthesized by pyrolysis of citric acid and urea at 200 °C by hydrothermal technique and characterized by photoluminescence, transmission electron microscopy (TEM), X-ray Photoelectron Spectrometer (XPS), and Fourier transform infrared spectrum (FTIR)...
March 20, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38513298/a-silk-based-hydrogel-containing-dexamethasone-and-lipoic-acid-microcrystals-for-local-delivery-to-the-inner-ear
#9
JOURNAL ARTICLE
Haixia Xiong, Peili Zhang, Dongcheng Wang, Zhimin Zhou, Jianjun Sun, Mingfang Diao
Local drug delivery has been exploited recently to treat hearing loss, as this method can both bypass the blood-labyrinth barrier and provide sustained drug release. Combined drug microcrystals (MCs) offer additional advantages for sensorineural hearing loss treatment via intratympanic (IT) injection due to their shape effect and combination strategy. In this study, to endow viscous effects of hydrogels, nonspherical dexamethasone (DEX) and lipoic acid (LA) MCs were incorporated into silk fibroin (SF) hydrogels, which were subsequently administered to the tympanic cavity to investigate their pharmaceutical properties...
March 16, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38502974/carrageenan-films-as-promising-mucoadhesive-ocular-drug-delivery-systems
#10
JOURNAL ARTICLE
Aleksandra V Volod'ko, Elvira Yu Son, Valery P Glazunov, Viktoriya N Davydova, Elga I Alexander-Sinkler, Svetlana A Aleksandrova, Miralda I Blinova, Irina M Yermak
Polymer mucoadhesive films being developed for use in ophthalmology represent a new tool for drug delivery and are considered an alternative to traditional dosage forms. Due to their mucoadhesive properties, carrageenans (CRGs) are widely used in various forms for drug delivery. In this study, films based on CRGs of various structural types (κ/β, κ, x, and λ) for use in ophthalmology were studied. The films were loaded with the active substance echinochrome (ECH), a sea urchin pigment used in ophthalmology...
March 16, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38492413/eudragit-s100-coated-nanodiamond-based-nanoparticles-as-an-oral-chemo-photothermal-delivery-system-for-local-treatment-of-colon-cancer
#11
JOURNAL ARTICLE
Yupei Su, Hao Pan, Jiahui Wang, Dandan Liu, Weisan Pan
Oral colonic nano-drug delivery system has received more and more attention in the treatment of colon cancer due to local precision treatment and reduction of drug system distribution. However, the complex and harsh gastrointestinal environment and the retention of nanoparticles in the colon limit its development. To this end, we designed Eudragit S100 (ES) coated nanoparticles (ES@PND-PEG-TPP/DOX). Polydopamine coated nanodiamond (PND) was modified with amino-functionalized polyethylene glycol (NH2 -PEG-NH2 ) and triphenylphosphine (TPP) successively...
March 13, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38508086/phyto-cosmeceutical-gel-containing-curcumin-and-quercetin-loaded-mixed-micelles-for-improved-anti-oxidant-and-photoprotective-activity
#12
JOURNAL ARTICLE
Monica Rp Rao, Pranjali Gaikwad, Poonam Misal, Santosh V Gandhi
Ultra Violet radiations induced skin damage and associated skin disorders are a widespread concern. The consequences of sun exposure include a plethora of dermal conditions like aging, solar urticaria, albinism and cancer. Sunscreens provide effective protection to skin from these damages. Besides FDA approved physical and chemical UV filters, phytoconstituents with their multi functionalities are emerging as frontrunners in Therapy of skin disorders. Objective of this study was to develop novel phyto-dermal gel (PDG) with dual action of sun protection and antioxidant potential using polymeric mixed micelles (PMMs) are nanocarriers...
March 12, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38492412/covalent-modification-of-%C3%AE-cyclodextrin-with-geraniol-an-antibacterial-agent-with-good-thermal-stability-solubility-and-biocompatibility
#13
JOURNAL ARTICLE
Xiaowei Ding, Xuerong Luo, Imran Mahmood Khan, Lin Yue, Yin Zhang, Zhouping Wang
Geraniol (Ger) is an essential oil molecule with excellent biological activity. High hydrophobicity and volatility limit its practical application. Cyclodextrins (CDs) are water-soluble cyclic oligosaccharides with hydrophobic cavities. Physical encapsulation of CDs to improve the solubility and stability of essential oil molecules is not satisfactory. Therefore, this study synthesized the γ-CD derivative (γ-CD-Ger) by grafting Ger onto γ-CD using a bromide-mediated method. Compared to the inclusion complexes (γ-CD/Ger) formed by both, the derivatives exhibit better solubility and thermal stability...
March 12, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38492411/surfactant-based-supramolecular-dye-assembly-a-highly-selective-and-economically-viable-platform-for-quantification-of-heparin-antidote
#14
JOURNAL ARTICLE
Soumyadeep Sarkar, Goutam Chakraborty, Haridas Pal
Herein, we have employed a supramolecular assembly of a cationic dye, LDS-698 and a common surfactant sodium dodecyl sulfate (SDS) as a turn-on fluorescent sensor for protamine (Pr) detection. Addition of cationic Pr to the solution of dye-surfactant complex brings negatively charged SDS molecules together through strong electrostatic interaction, assisting aggregation of SDS way before its critical micellar concentration (CMC). These aggregates encapsulate the dye molecules within their hydrophobic region, arresting non-radiative decay channels of the excited dye...
March 12, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38513299/promoting-effect-of-phosvitin-in-the-mineralization-of-eggshell-inner-membrane-with-the-application-in-osteogenic-induction-scaffold
#15
JOURNAL ARTICLE
Wei Liu, Qiancheng Zhao, Cuie Tang, Zhaoxia Cai, Yongguo Jin, Dong Uk Ahn, Xi Huang
Exploring affordable and easily prepared inorganic-organic hybrid membrane materials has attracted a great interest in the bone repair field. This study is based on biomimetic mineralization technique to study the role of phosvitin (PV) in the mineralized process of eggshell inner membrane. Results showed that PV promoted the formation of hydroxyapatite on the eggshell inner membrane surface, and the phosvitin content in the simulated body fluid was decreased during the mineralization process. Besides, in vitro preosteoblast experiments indicated that mineralized membrane with PV exhibited more conducive to cell proliferation and differentiation than that mineralized membrane without PV...
March 11, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38508085/giant-vesicles-form-in-physiological-saline-and-encapsulate-pdna-by-the-modified-electroformation-method
#16
JOURNAL ARTICLE
Dingshan Zhang, Yangruizi Zhang, Yao Xiao, Yiting Wang, Yong Shen, Zhibiao Wang, Hai Qiao
Giant vesicles (GVs) are used to study the structures and functions of cells and cell membranes. Electroformation is the most commonly used method for GV preparation. However, the electroformation of GVs is hindered in highly concentrated ionic solutions, limiting their application as cell models for research under physiological conditions. In this study, giant multilayer vesicles were successfully generated in physiological saline using a modified electroformation device by adding an insulating layer between the two electrode plates...
March 11, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38484445/advances-in-self-assembled-nanotechnology-in-tumor-therapy
#17
REVIEW
Yanting Kuang, Zhaokai Li, Hang Chen, Xinyu Wang, Yan Wen, Jianming Chen
The emergence of nanotechnology has opened up a new way for tumor therapy. Among them, self-assembled nanotechnology has received extensive attention in medicine due to its simple preparation process, high drug-loading capacity, low toxicity, and low cost. This review mainly summarizes the preparation methods of self-assembled nano-delivery systems, as well as the self-assembled mechanism of carrier-free nanomedicine, polymer-carried nanomedicine, polypeptide, and metal drugs, and their applications in tumor therapy...
March 11, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38479261/calcium-based-mofs-as-scaffolds-for-shielding-immobilized-lipase-and-enhancing-its-stability
#18
JOURNAL ARTICLE
Lili Xu, Xinyue Geng, Qi Li, Moju Li, Shu Chen, Xiangnan Liu, Xusheng Dai, Xiuhuan Zhu, Xuekun Wang, Hongbo Suo
The enzyme immobilization technology has become a key tool in the field of enzyme applications; however, improving the activity recovery and stability of the immobilized enzymes is still challenging. Herein, we employed a magnetic carboxymethyl cellulose (MCMC) nanocomposite modified with ionic liquids (ILs) for covalent immobilization of lipase, and used Ca-based metal-organic frameworks (MOFs) as the support skeleton and protective layer for immobilized enzymes. The ILs contained long side chains (eight CH2 units), which not only enhanced the hydrophobicity of the carrier and its hydrophobic interaction with the enzymes, but also provided a certain buffering effect when the enzyme molecules were subjected to compression...
March 9, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38479260/evaluating-the-hypolipidemic-effect-of-garlic-essential-oil-encapsulated-in-a-novel-double-layer-delivery-system
#19
JOURNAL ARTICLE
Xueli Zhang, Xu Guo, Jinyue Sun, Yingying Chen, Mengqi Zhang, Xiaozhen Tang, Wenliang Wang, Jesus Simal-Gandara, Huiying Xu, Ningyang Li, Chao Liu
The limited application of garlic essential oil (GEO) is attributed to its pungent taste, poor water solubility and low bioavailability. Liposomes are nontoxic, biodegradable and biocompatible, and β-cyclodextrin can inhibit undesirable odors and improve the stability and bioavailability. Thus a promising dual-layer GEO β-cyclodextrin inclusion compound liposome (GEO-DCL) delivery system with both advantages was designed and prepared in this study. Experimental results indicated that the encapsulation efficiency of GEO-DCLs was 5% higher than that of GEO liposomes (GEO-CLs), reaching more than 88%...
March 7, 2024: Colloids and Surfaces. B, Biointerfaces
https://read.qxmd.com/read/38479259/facile-synthesis-of-manganese-hafnium-nanocomposites-for-multimodal-mri-ct-imaging-and-in-vitro-photodynamic-therapy-of-colon-cancer
#20
JOURNAL ARTICLE
Mingyue Cui, Zhe Tang, Zahoor Ahmad, Chunshu Pan, Yuguang Lu, Kamran Ali, Shuqi Huang, Xiaoqing Lin, Abdul Wahab, M Zubair Iqbal, Xiangdong Kong
Precise diagnosis of complex and soft tumors is challenging, which limits appropriate treatment options to achieve desired therapeutic outcomes. However, multifunctional nano-sized contrast enhancement agents based on nanoparticles improve the diagnosis accuracy of various diseases such as cancer. Herein, a facile manganese-hafnium nanocomposites (Mn3 O4 -HfO2 NCs) system was designed for bimodal magnetic resonance imaging (MRI)/computed tomography (CT) contrast enhancement with a complimentary function of photodynamic therapy...
March 6, 2024: Colloids and Surfaces. B, Biointerfaces
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