Yoshitaka Kawai, Yo Kishimoto, Hisanobu Tamaki, Takashi Fujiwara, Ryo Asato, Koji Ushiro, Shogo Shinohara, Shinpei Kada, Shinji Takebayashi, Tsuyoshi Kojima, Shuya Otsuki, Masakazu Miyazaki, Yohei Kumabe, Koichi Omori
The operative procedure in the surgical treatment of parathyroid carcinoma differs from that of benign hyperparathyroidism. However, preoperative differentiation is often difficult. This study elucidated how clinicians diagnose parathyroid carcinoma and the relationship between preoperative diagnosis and the operative course. Using a retrospective chart review, twenty cases of parathyroid carcinoma from nine participating centers were examined. In 11 cases with preoperative suspicion of malignancy, at least one of these three features was found: elevated serum calcium level (>14 mg/dL), palpable mass, and irregular margin on ultrasonography...
August 26, 2023: Endocrine Journal