Yintao Chang, Qianyu Han, Xiaochen Bao, Mingdong Wang, Yuxiang Jin, Siang Zhang, Xuewei Zhao, Yiqun Fang, Lei Xue
BACKGROUND: This study sought to investigate therapeutic effects of hydrogen-rich saline (HRS) combined with hyperbaric oxygen (HBO2) in an experimental rat model of acute lung injury (ALI). METHOD: Forty male Sprague-Dawley rats were randomly divided into sham, LPS, LPS + HBO2, LPS + HRS, and LPS + HBO2 + HRS groups. After an intratracheal injection of LPS-induced ALI, the rats were given a single-agent HBO2 or HRS or HBO2 + HRS treatment. The treatments were continued for three days in this experimental rat model of ALI...
2023: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc