Daysiane de Oliveira, Gabriel Paulino Luiz, Rahisa Scussel, Mirian Ivens Fagundes, Nathália Coral Galvani, Jessica da Silva Abel, Rubya Pereira Zaccaron, Gustavo de Bem Silveira, Thiago Antônio Moretti de Andrade, Paulo Cesar Lock Silveira, Ricardo Andrez Machado-de-Ávila
Introduction: The search for fast and efficient treatment for dermonecrotic lesions caused by the venom of the spider from the Loxosceles simillis , is a demand in health. Prednisolone is one of the most used drugs, however it has side effects. In this context, addictionally gold nanoparticles (GNPs) have anti-inflammatory, antioxidant, and antibacterial properties. The use of photobiomodulation has show to be efficient in the process of tissue repair. Therefore, the purpose of this study was to investigate the anti-inflammatory effect of photobiomodulation and GNPs associated or not with a low concentration of prednisolone in animal models of dermonecrotic lesion...
December 28, 2023: Journal of Drug Targeting