Alberto Gabrieli, Caterina Barberi, Caterina Compostella, Michela Azzolini, Andrea Butturini, Gabriele Larger, Lara Boldo, Matteo Paganini, Roberta Levato, Andrea Ventura
Local anesthetic systemic toxicity (LAST) is a potentially life-threatening complication that may occur after local anesthetic injection. After reaching the systemic circulation, cardiovascular and central nervous system derangements may appear, with potentially fatal complications if left untreated. The pillars for LAST treatment are advanced life support measures, airway and seizure management, and a 20% lipid emulsion intravenous administration. When occurring in the prehospital setting, LAST is difficult to recognize, mostly because of its features overlapping with other acute conditions...
2024: Air Medical Journal