journal
https://read.qxmd.com/read/36952531/hit-and-run-bilateral-massive-intraocular-lymphomatous-infiltration-after-car-t-therapy
#1
JOURNAL ARTICLE
Abdullah Abou-Samra, Sloane McTavish, Rachel Whitehair, Yevgeniy Eugene Shildkrot
PURPOSE: We report a case of bilateral intraocular infiltration of DLBCL after CAR-T therapy. METHODS: Retrospective case report. RESULTS: A 62-year-old Caucasian male with medical history of high-grade DLBCL presented with papillitis and vitritis upon completion of CAR-T therapy. Thorough infectious and diagnostic work-ups were performed. Diagnostic vitreous tap revealed intraocular lymphoma. The patient received external beam radiotherapy to both orbits with dramatic improvement in disc edema and vitritis...
March 23, 2023: Ocular Immunology and Inflammation
https://read.qxmd.com/read/36952513/acute-sterile-endophthalmitis-following-intravitreal-rituximab-injection-in-primary-vitreoretinal-lymphoma-case-series
#2
JOURNAL ARTICLE
Buse Guneri Beser, Hakan Demirci
OBJECTIVE OR PURPOSE: To describe sterile endophthalmitis following intravitreal rituximab (Rituxan, Genentech) injection for treatment of vitreoretinal lymphoma (VRL). DESIGN: Retrospective case series. SUBJECTS, PARTICIPANTS, AND/OR CONTROLS: Medical records of biopsy-proven VRL patients who received intravitreal rituximab (RTX) between January 2011 and December 2021 in Kellogg Eye Center, University of Michigan were reviewed. 3 patients presented with sterile endophthalmitis after the second dose of intravitreal RTX were included...
March 23, 2023: Ocular Immunology and Inflammation
https://read.qxmd.com/read/36952481/coincidence-of-candida-endophthalmitis-and-aspergillus-and-pneumocystis-jirovecii-pneumonia-in-a-covid-19-patient-case-report
#3
JOURNAL ARTICLE
Shabnam Tehrani, Sahba Fekri, Hakan Demirci, Amir Mohammad Nourizadeh, Alireza Kashefizadeh, Mohammad Amin Shahrbaf, Amirreza Keyvanfar, Fatemeh Maghsoudi Nejad
INTRODUCTION: Coronavirus disease 2019 (COVID-19) is associated with immune system dysfunction and makes patients vulnerable to opportunistic infections. This report presents a patient with a history of COVID-19, suffering from opportunistic infections. CASE DESCRIPTION: We reported a 64-year-old man complaining of progressive visual loss in his left eye, who had previously been hospitalized for three weeks due to COVID-19. In the ophthalmologic assessment, large foci of dense subretinal and intraretinal infiltrations involving the macula were observed (compatible with endogenous fungal endophthalmitis)...
March 23, 2023: Ocular Immunology and Inflammation
https://read.qxmd.com/read/36943728/serum-vitamin-d-levels-as-biomarkers-in-patients-with-autoimmune-uveitis-and-their-possible-correlation-with-disease-activity
#4
JOURNAL ARTICLE
Karine Koller, Kimble Matos Teixeira Fonseca, Kelsy N Areco, Yuslay Fernández-Zamora, Luci Meire Pereira Silva, Ricardo Pedro Casaroli-Marano, Cicero Galli Coimbra, Cristina Muccioli
This study investigated the correlation between serum vitamin D levels and intraocular inflammation in patients with autoimmune uveitis (AIU). We evaluated 67 patients with active and inactive AIU and measured their serum 25-hydroxyvitamin D [25(OH)D] concentration, sun exposure habits, number of relapses, and complications. Of the patients evaluated, 85% had significantly lower vitamin D levels, and patients with active uveitis had lower 25(OH)D levels than those with inactive uveitis. The odds of developing active uveitis decreased by 6% with each 1-unit increase in 25(OH)D...
March 21, 2023: Ocular Immunology and Inflammation
https://read.qxmd.com/read/36931285/risk-factors-associated-with-unexpected-refractive-outcomes-in-uveitic-cataract-surgery
#5
JOURNAL ARTICLE
Daniel J Lee, Steven Seto, Mark Banghart, Kelly Boyd, Catherine Thuruthumaly, Eric B Suhler, Laura J Kopplin
OBJECTIVE: Assess refractive outcomes following uveitic cataract surgery and identify factors associated with deviations from the target refractive goal. METHODS: A multicenter retrospective chart review was performed for 216 subjects with uveitis undergoing cataract surgery. Prediction error was calculated and tested for association with demographic and clinical characteristics using single variable and multiple regression analysis. RESULTS: 39...
March 17, 2023: Ocular Immunology and Inflammation
https://read.qxmd.com/read/36898006/surgical-glaucoma-treatment-in-patients-with-juvenile-idiopathic-arthritis-associated-uveitis-results-after-trabeculectomy-or-ahmed-glaucoma-valve-implantation
#6
JOURNAL ARTICLE
Karen Glandorf, Kai Rothaus, Karoline Baquet-Walscheid, Carsten Heinz, Arnd Heiligenhaus
PURPOSE: Patients with juvenile idiopathic arthritis (JIA) associated uveitis (JIAU) are at risk for secondary glaucoma, frequently requiring surgical management. We compared the success rates for trabeculectomy (TE) and Ahmed glaucoma valve (AGV) implantation. METHODS: We conducted a retrospective analysis of TE (45 eyes), primary AGV (pAGV) (7 eyes), or secondary AGV (sAGV) implantation after TE (11 eyes) in JIAU at the 2-year follow-up. RESULTS: All groups achieved significant pressure reduction...
March 10, 2023: Ocular Immunology and Inflammation
https://read.qxmd.com/read/36897992/clinical-features-long-term-outcomes-and-prognostic-factors-of-eales-disease-in-korean-patients
#7
JOURNAL ARTICLE
Seung Min Lee, Jae Hoon Jung, Junwon Lee, Eun Young Choi, Joo Youn Shin, Min Kim
PURPOSE: We studied Korean patients with Eales' disease to document clinical features, long-term outcomes, and explore its association with TB, given South Korea's high TB burden. METHODS: We retrospectively reviewed medical records of Eales' disease patients for clinical characteristics, long-term outcomes, and its association with TB. RESULTS: Among 106 eyes, the average age of diagnosis was 39.28 years, with 82.7% male and 58.7% having unilateral involvement...
March 10, 2023: Ocular Immunology and Inflammation
https://read.qxmd.com/read/36897959/penicillin-responsive-presumed-seronegative-ocular-syphilis-in-a-patient-with-human-immunodeficiency-virus-a-case-report-and-review-of-the-literature
#8
JOURNAL ARTICLE
Michael B Green, Joshua S Agranat, Samaneh Davoudi, Nedda Sanayei, Steven Ness
Ocular and systemic syphilis are well known to mimic other clinical entities making them challenging to diagnose in many cases. Syphilis testing plays an important role in diagnosis and timely treatment. Here we describe a patient with untreated human immunodeficiency virus (HIV) infection who presented with bilateral panuveitis with repeatedly negative syphilis serologies. In light of worsening retinitis while on aggressive anti-viral treatment and in consideration of the clinical suspicion for syphilitic uveitis, intravenous penicillin was initiated empirically...
March 10, 2023: Ocular Immunology and Inflammation
https://read.qxmd.com/read/36897931/retrolental-bullous-retinal-detachment-as-the-presenting-feature-of-vogt-koyanagi-harada-disease-in-an-elderly-indian-female-diagnostic-and-therapeutic-challenge
#9
JOURNAL ARTICLE
Nitin Kumar Menia, Reema Bansal, Vishali Gupta
PURPOSE: To report an atypical case of Vogt-Koyanagi-Harada (VKH) disease with retrolental bullous retinal detachment (RD). METHODS: A case report. CASE: A 67-year-old Indian woman with bilateral, gradual visual loss presented with both eyes light perception, keratic precipitates, 2+ cells and bullous RD, which was retrolental in right eye (RE). Systemic investigations were unremarkable. She received systemic corticosteroids, and underwent pars plana vitrectomy (PPV) in left eye (LE)...
March 10, 2023: Ocular Immunology and Inflammation
https://read.qxmd.com/read/36893445/dual-energy-x-ray-absorptiometry-scan-utilization-and-skeletal-fragility-among-non-infectious-uveitis-patients-exposed-to-oral-glucocorticoids
#10
JOURNAL ARTICLE
Nicholas J Butler, Devin Cohen, Yinxi Yu, John H Kempen, Lucia Sobrin, Brian L VanderBeek
INTRODUCTION: Currently, little is known regarding bone health surveillance for glucocorticoid-exposed non-infectious uveitis (NIU) patients or their baseline risks of skeletal fragility outcomes. METHODS: Using claims data, we calculated rates of dual-energy x-ray absorptiometry (DXA) screening for glucocorticoid-exposed NIU and rheumatoid arthritis (RA) patients. Separately, we compared risks of skeletal fragility metrics amongst NIU patients, RA patients, and controls, independent of glucocorticoid use...
March 9, 2023: Ocular Immunology and Inflammation
https://read.qxmd.com/read/36892932/surgical-outcomes-of-penetrating-canaloplasty-in-patients-with-uncontrolled-posner-schlossman-syndrome-a-prospective-study
#11
JOURNAL ARTICLE
Wenqing Ye, Lin Fu, Jinxin Li, Shuqing Zhu, Shaodan Zhang, Juan Gu, Yi Jiang, Yuanbo Liang
PURPOSE: To evaluate the surgical outcomes in patients with Posner-Schlossman syndrome (PSS) at one year. METHODS: A prospective interventional study in PSS patients with penetrating canaloplasty. Main outcome measure was success rate (6 mmHg≤ intraocular pressure (IOP) ≤ 21 mmHg) with or without medications. RESULTS: Thirteen eyes in 13 patients with PSS underwent complete catheterization. The mean IOP and medications (Meds) were reduced to 16...
March 9, 2023: Ocular Immunology and Inflammation
https://read.qxmd.com/read/36892911/panuveitis-by-coinfection-with-toxoplasma-gondii-and-epstein-barr-virus-should-we-use-antiviral-therapy-a-case-report
#12
JOURNAL ARTICLE
Laura Zarate-Pinzon, Luisa Fernanda Peña-Pulgar, Carlos Cifuentes-González, William Rojas-Carabali, María José Salgar, Alejandra de-la-Torre
BACKGROUND: To report the atypical presentation and treatment in a case of Toxoplasma gondii (Tg) and Epstein Barr Virus ( EBV ) intraocular coinfection. CASE PRESENTATION: A 60-year-old male patient who presented anterior hypertensive uveitis followed by a new finding of a yellowish-white fluffy retinochoroidal lesion in the superior-temporal quadrant. He was initially treated with antiviral therapy without improvement. Next, due to the Tg infection suspicion, anti-toxoplasmic treatment was added, and therapeutic and diagnostic vitrectomy was performed along with intravitreal clindamycin...
March 9, 2023: Ocular Immunology and Inflammation
https://read.qxmd.com/read/36888981/beaded-pearls-appearance-in-syphilitic-chorioretinitis
#13
JOURNAL ARTICLE
Anup Kelgaonkar, Anamika Patel, Mudit Tyagi, Tapas Ranjan Padhi, Soumyava Basu, Peter McCluskey
PURPOSE: To report an atypical case of bilateral syphilitic chorioretinitis. METHODS: A case report. RESULTS: A young male presented with bilateral pigmentary retinal changes along with multifocal chorioretinal lesions along the blood vessels giving a "beaded pearl" appearance. He was a hitherto undiagnosed case of human immunodeficiency virus infection and was diagnosed to have syphilis. He had a favourable visual and anatomical outcome following treatment...
March 8, 2023: Ocular Immunology and Inflammation
https://read.qxmd.com/read/36888980/bilateral-retinal-artery-occlusions-and-uveitis-as-the-first-manifestation-of-crohn-s-disease
#14
JOURNAL ARTICLE
Li-An Wu, Yi-Ching Chu, Jia-Kang Wang, Yung-Ray Hsu
PURPOSE: To present a case of newly diagnosed Crohn's disease, in which retinal artery occlusion (RAO) with uveitis was the first clinical manifestation. CASE DESCRIPTION: A 55-year-old man presented with bilateral blurred vision, with decreased best corrected visual acuity (BCVA) to light perception (right eye, RE) and 20/40 (left eye, LE). Ophthalmological examination revealed bilateral iritis, vitritis, disc edema, and retinal vascular occlusions. Because of concurrent fever and leukocytosis, a systemic infection was highly suspected...
March 8, 2023: Ocular Immunology and Inflammation
https://read.qxmd.com/read/36888977/idiopathic-hypertrophic-cranial-pachymeningitis-with-scleritis-and-optic-disc-involvement-a-case-report-and-literature-review
#15
JOURNAL ARTICLE
Xuecheng Cai, Nan Hong, Huiyan Li, Bo Jiang, Jianxia Fang, Jiechao Shao, Hui Liang, Ye Shen
This report describes a case of idiopathic hypertrophic cranial pachymeningitis (IHCP) with scleritis and optic disc involvement. The patient was a 56-year-old woman with chief complaints of fever, headache, binocular pain, and redness. Biochemical and immunological indicators, cranial magnetic resonance imaging, and relevant ophthalmological examinations were employed for evaluation. Infectious and neoplastic causes were excluded. Typical meningeal thickening and enhancement on magnetic resonance imaging revealed IHCP...
March 8, 2023: Ocular Immunology and Inflammation
https://read.qxmd.com/read/36884356/scleritis-and-episcleritis-following-coronavirus-disease-covid-19-vaccination
#16
JOURNAL ARTICLE
Srinivasan Sanjay, Ashit Handa, Ankush Kawali, Rohit Shetty, Sai Bhakti Mishra, Padmamalini Mahendradas
INTRODUCTION: Coronavirus disease (COVID-19) vaccines have been reported to have ocular side effects including scleritis and episcleritis. PURPOSE: To report scleritis and episcleritis within a month following administration of COVID-19 vaccine. METHODS: Retrospective case series. RESULTS: 15 eyes of 12 consecutive patients with scleritis and episcleritis from March 2021 to September 2021 were included. The mean time of onset of symptoms in patients with scleritis was 15...
March 8, 2023: Ocular Immunology and Inflammation
https://read.qxmd.com/read/36881580/comparison-of-retinal-structure-using-optical-coherence-tomography-angiography-between-persons-with-and-without-hiv-infection
#17
JOURNAL ARTICLE
Luana Nogueira Brandão, Rodrigo Pessoa Cavalcanti Lira, Tiago Eugênio Faria E Arantes, Candice Carolina de Mesquita Costa, Emídio Dias da Silva Neto, Paulo Sérgio Ramos de Araújo, Vasco Bravo-Filho
HIV retinal microangiopathy is an important predictor for increased risk of mortality. Optical coherence tomography angiography (OCTA) can investigate microvascular changes resulting from retinal diseases. Study included 25 persons with HIV and 25 healthy persons. OCTA evaluated the vascularization of retinal layers, choriocapillary, and optic disk. HIV group had lower vessel flow density (VFD) in superficial plexus. No difference was observed in the deep plexus. VFD of the optic disk and peripapillary region showed no difference between the groups...
March 7, 2023: Ocular Immunology and Inflammation
https://read.qxmd.com/read/36867863/corticosteroids-decrease-the-incidence-and-activity-of-choroidal-neovascularization-in-patients-with-punctuate-inner-choroidopathy-or-multifocal-choroiditis
#18
JOURNAL ARTICLE
Aliénor Vienne-Jumeau, Antoine P Brézin, Marie Seminel, Florence Ribeaudeau-Saindelle, Elodie Bousquet
PURPOSE: To assess the effect of corticosteroids (CS) on choroidal neovascularization (CNV) occurrence and recurrence of activity over 2 years in patients with punctate inner choroidopathy (PIC) or multifocal choroiditis (MFC). METHODS: Retrospective longitudinal study. Previous use of CS was analyzed between group without CNV and group with CNV occurrence and recurrence. RESULTS: Thirty-six patients were included. Patients with CNV were less likely to have received CS in the 6 months following PIC or MFC diagnosis (17% versus 65%, p-value = 0...
March 3, 2023: Ocular Immunology and Inflammation
https://read.qxmd.com/read/36867862/comparison-of-clinical-characteristics-between-rubella-virus-and-cytomegalovirus-associated-chronic-unilateral-anterior-uveitis
#19
JOURNAL ARTICLE
Klio I Chatzistefanou, Ioannis Halkiadakis, Stelios Maselos, Nikolaos N Markomichelakis
PURPOSE: To identify the clinical characteristics that may predict the diagnosis of Rubella virus (RV) or Cytomegalovirus (CMV) among cases of chronic treatment resistant or steroid dependent unilateral anterior uveitis (AU). METHODS: Thirty-three consecutive patients with a diagnosis of CMV and 32 patients with RV chronic AU were enrolled. The respective frequency of certain demographic and clinical characteristics was compared between the two groups. RESULTS: The presence of abnormal vessels in the anterior chamber angle (75% and 6...
March 3, 2023: Ocular Immunology and Inflammation
https://read.qxmd.com/read/36867499/refractory-candida-dubliniensis-retinitis-in-an-immunocompetent-patient
#20
JOURNAL ARTICLE
Fahmeeda Murtaza, Austin Pereira, H Nida Sen, Henry E Wiley, Panos G Christakis
BACKGROUND: Fungal endophthalmitis is an intraocular infection that rarely develops in immunocompetent individuals. CASE: A 35-year-old healthy, immunocompetent male presented with a 1-week history of pain and redness in the left eye. Visual acuity was 20/50. Dilated fundus examination revealed focal chorioretinitis in the posterior pole with associated vitritis, suspicious for a fungal etiology. He was started empirically on oral voriconazole and valacyclovir. A comprehensive systemic workup returned negative...
March 3, 2023: Ocular Immunology and Inflammation
journal
journal
31419
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.