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Seizure: the Journal of the British Epilepsy Association | Page 2

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https://read.qxmd.com/read/31288205/seeg-guided-radiofrequency-thermocoagulation-of-epileptic-foci-in-the-paediatric-population-feasibility-safety-and-efficacy
#21
Mathilde Chipaux, Delphine Taussig, Georg Dorfmuller, Nathalie Dorison, Martin M Tisdall, Stewart G Boyd, Rachel Thornton, Christin Eltze, Martine Fohlen, Helen J Cross, Sarah Ferrand-Sorbets
PURPOSE: Focal epilepsy in children may be refractory to pharmacological treatment and surgical resection may be an appropriate option. When invasive electroencephalogram is required in the presurgical evaluation, depth electrodes can be used to create focal lesions in the epileptogenic zone using radiofrequency thermocoagulation (RFTC), to disrupt the epileptogenic zone. METHODS: This study aimed to assess the efficacy and safety of RFTC in a paediatric population of 46 patients...
July 3, 2019: Seizure: the Journal of the British Epilepsy Association
https://read.qxmd.com/read/31306872/epilepsy-and-ultra-structural-heart-changes-the-role-of-catecholaminergic-toxicity-and-myocardial-fibrosis-what-can-we-learn-from-cardiology
#22
REVIEW
Guilherme L Fialho, Peter Wolf, Roger Walz, Katia Lin
In this article, we explore the interaction of brain and heart in patients with epilepsy (PWE), focusing on new insights into possible pathways from epilepsy, catecholaminergic toxicity, subtle cardiac changes and sudden death. Initial evidence and biological plausibility point to an interaction between autonomic dysfunction, higher sympathetic drive, myocardial catecholaminergic toxicity and cardiac fibrosis resulting in subtle myocardial changes in structure, function, arrhythmogenesis and/or a heart failure-like phenotype in PWE...
July 2, 2019: Seizure: the Journal of the British Epilepsy Association
https://read.qxmd.com/read/31280099/accuracy-of-expert-predictions-of-seizure-freedom-after-epilepsy-surgery
#23
Juri-Alexander Witt, Tamara Krutenko, Maria Gädeke, Rainer Surges, Christian E Elger, Christoph Helmstaedter
PURPOSE: To evaluate the accuracy of expert estimations of achieving seizure freedom after epilepsy surgery in the context of presurgical patient counseling. METHOD: The retrospective study comprised a random sample of 200 patients who underwent any type of resective epilepsy surgery at the University of Bonn Epilepsy Center and the routine 1-year postoperative control visit in the years from 2008-2016. The prediction by a team of epileptologists and the actual seizure outcome were extracted from the pre- and postsurgical medical files, respectively...
June 30, 2019: Seizure: the Journal of the British Epilepsy Association
https://read.qxmd.com/read/31279168/severe-early-onset-developmental-and-epileptic-encephalopathy-dee-associated-with-novel-compound-heterozygous-pathogenic-variants-in-slc25a22-case-report-and-literature-review
#24
Thea Giacomini, Livia Pisciotta, Giulia Prato, Irene Meola, Federico Zara, Chiara Fiorillo, Serena Baratto, Mariasavina Severino, Elisa De Grandis, Maria Margherita Mancardi
No abstract text is available yet for this article.
June 27, 2019: Seizure: the Journal of the British Epilepsy Association
https://read.qxmd.com/read/31252362/seizure-induced-shoulder-dislocations-case-series-and-review-of-the-literature
#25
Lisa Langenbruch, Carolin Rickert, Georg Gosheger, Dominik Schorn, Benedikt Schliemann, Tobias Brix, Christian E Elger, Sven G Meuth, Stjepana Kovac
PURPOSE: We aimed to identify clinical characteristics of patients with shoulder dislocations caused by an epileptic seizure. METHODS: In our retrospective analysis, we identified 15 patients, recorded over an 8-year period, who were diagnosed with shoulder dislocations in the setting of a bilateral tonic-clonic seizure. RESULTS: Patients were almost exclusively male (13/15) and drug-naïve patients suffering their first or second seizure (14/15)...
June 20, 2019: Seizure: the Journal of the British Epilepsy Association
https://read.qxmd.com/read/31238196/sustained-seizure-freedom-with-transcutaneous-vagal-nerve-stimulation-in-drug-resistant-epilepsy-caused-by-subcortical-band-heterotopias
#26
Randi von Wrede, Susanna Moskau-Hartmann, Theodor Rüber, Christoph Helmstaedter, Rainer Surges
No abstract text is available yet for this article.
June 20, 2019: Seizure: the Journal of the British Epilepsy Association
https://read.qxmd.com/read/31229856/predictive-performances-of-stess-and-emse-in-a-norwegian-adult-status-epilepticus-cohort
#27
Line Bédos Ulvin, Erik Taubøll, Ketil Berg Olsen, Kjell Heuser
PURPOSE: "Status Epilepticus Severity Score" (STESS) and "Epidemiology-based Mortality Score in Status Epilepticus" (EMSE) are two clinical scoring systems aiming to predict mortality in status epilepticus (SE). The objective of this study was to compare their predictive performances in a cohort of 151 SE-patients from Oslo University Hospital in the period 2001-2017. METHOD: Variables used to calculate STESS (age, previous seizures, worst SE-semiology, level of consciousness) and two different versions of EMSE, EMSE-EAC (etiology, age, comorbidities) and EMSE-EACE (etiology, age, comorbidities, EEG-pattern), as well as outcome were collected retrospectively...
June 20, 2019: Seizure: the Journal of the British Epilepsy Association
https://read.qxmd.com/read/31323566/the-onset-of-pediatric-refractory-status-epilepticus-is-not-distributed-uniformly-during-the-day
#28
Iván Sánchez Fernández, Marina Gaínza-Lein, Nicholas S Abend, Marta Amengual-Gual, Anne Anderson, Ravindra Arya, J Nicholas Brenton, Jessica L Carpenter, Kevin E Chapman, Justice Clark, Raquel Farias-Moeller, William Davis Gaillard, Tracy A Glauser, Joshua Goldstein, Howard P Goodkin, Réjean M Guerriero, Kurt Hecox, Michele Jackson, Kush Kapur, Sarah A Kelley, Eric H W Kossoff, Yi-Chen Lai, Tiffani L McDonough, Mohamad A Mikati, Lindsey A Morgan, Edward J Novotny, Adam P Ostendorf, Eric T Payne, Katrina Peariso, Juan Piantino, James J Riviello, Kumar Sannagowdara, Carl E Stafstrom, Robert C Tasker, Dmitry Tchapyjnikov, Alexis A Topjian, Alejandra Vasquez, Mark S Wainwright, Angus Wilfong, Korwyn Williams, Tobias Loddenkemper
PURPOSE: To evaluate whether the onset of pediatric refractory status epilepticus (rSE) is related to time of day. METHOD: We analyzed the time of day for the onset of rSE in this prospective observational study performed from June 2011 to May 2019 in pediatric patients (1 month to 21 years of age). We evaluated the temporal distribution of pediatric rSE utilizing a cosinor analysis. We calculated the midline estimating statistic of rhythm (MESOR) and amplitude...
June 18, 2019: Seizure: the Journal of the British Epilepsy Association
https://read.qxmd.com/read/31234050/surgical-outcomes-related-to-invasive-eeg-monitoring-with-subdural-grids-or-depth-electrodes-in-adults-a-systematic-review-and-meta-analysis
#29
Marton Toth, Kata Szilvia Papp, Noemi Gede, Kornelia Farkas, Sandor Kovacs, Jean Isnard, Koichi Hagiwara, Csilla Gyimesi, Diana Kuperczko, Tamas Doczi, Jozsef Janszky
PURPOSE: Resective epilepsy surgery based on an invasive EEG-monitors performed with subdural grids (SDG) or depth electrodes (stereo-electroencephalography, SEEG) is considered to be the best option towards achieving seizure-free state in drug-resistant epilepsy. The authors present a meta-analysis, due to the lack of such a study focusing on surgical outcomes originating from SDG- or SEEG-monitors. METHOD: English-language studies published until May 2018, highlighting surgical outcomes were reviewed...
June 18, 2019: Seizure: the Journal of the British Epilepsy Association
https://read.qxmd.com/read/31394367/efficacy-of-phenobarbital-and-sodium-valproate-in-treating-convulsive-epilepsy-in-rural-northeast-china
#30
Jing Li, Dan Yang, Danyang Zhao, Nan Li, Weihong Lin
PURPOSE: Phenobarbital and sodium valproate are broad spectrum and inexpensive antiepileptic drugs that are used to treat convulsive epilepsy. We examined the therapeutic effects of phenobarbital and sodium valproate in patients with convulsive epilepsy in the rural northeast China, and discuss our efforts to ensure patients' compliance. METHODS: Patients with convulsive epilepsy were screened by trained township health center doctors. Patients in the phenobarbital group were enrolled between January 2011 and December 2012, and followed up until December 2017...
June 15, 2019: Seizure: the Journal of the British Epilepsy Association
https://read.qxmd.com/read/31247399/two-chinese-siblings-with-two-novel-kctd7-mutations-have-dystonia-or-seizures-and-epileptic-discharge-on-electroencephalograms
#31
Lifang Dai, Changhong Ding, Fang Fang
No abstract text is available yet for this article.
June 15, 2019: Seizure: the Journal of the British Epilepsy Association
https://read.qxmd.com/read/31323565/epidemiology-of-children-with-epilepsy-at-a-tertiary-referral-centre-in-south-africa
#32
Sally Ackermann, Stanzi Le Roux, Jo M Wilmshurst
PURPOSE: This retrospective observational hospital-based study assessed the characteristics of children with epilepsy in a sub-Saharan African tertiary service over a 10-year period. METHODS: Children with a primary or secondary diagnosis of epilepsy seen during the study period were identified from the departmental database. Demographic and clinical data were collected from the database and available medical records. RESULTS: Of 4701 children managed in the neurology service, 2407 children (51%) had epilepsy...
June 12, 2019: Seizure: the Journal of the British Epilepsy Association
https://read.qxmd.com/read/31226566/the-prevalence-and-clinical-features-of-epileptic-seizures-in-a-memory-clinic-population
#33
John Baker, Tina Libretto, William Henley, Adam Zeman
PURPOSE: To determine the prevalence and clinical features of epileptic seizures occurring in a memory clinic population. METHOD: We recruited patients receiving a diagnosis of dementia or mild cognitive impairment (MCI) at a regional memory clinic. We interviewed patients and informants using a proforma designed to elicit symptoms suggestive of epilepsy. Informants also completed the Clinical Dementia Rating Scale (CDR) and the Cambridge Behavioural Inventory- Revised (CBI-R)...
June 12, 2019: Seizure: the Journal of the British Epilepsy Association
https://read.qxmd.com/read/31212191/post-ictal-cotard-delusion-in-focal-epilepsy-patients
#34
Young Eun Gil, Jun Young Choi, Tae Joon Kim, Sun Ah Park, Kyoon Huh
No abstract text is available yet for this article.
June 12, 2019: Seizure: the Journal of the British Epilepsy Association
https://read.qxmd.com/read/31207395/head-first-review-of-epilepsy-head-injury-risk-and-protection
#35
REVIEW
Caryn Jory, Katy Oak, Catriona Organ, Brendan Mclean, Rohit Shankar
INTRODUCTION: The causes of falls and resultant head injuries in people with epilepsy are complex and represent important clinical issues significantly impacting on safety, quality of life and long-term prognosis. A general solution for many years has been to provide helmets for head protection. There is poor understanding of the influencing risk factors and solutions to give person-centred clinical advice. METHODS: A focused narrative review was conducted to investigate the risk factors for seizure-related head injuries and evidence of current helmets to offer protection...
June 12, 2019: Seizure: the Journal of the British Epilepsy Association
https://read.qxmd.com/read/31207393/pediatric-onset-psychogenic-nonepileptic-seizures-a-retrospective-international-multicenter-study
#36
Ali A Asadi-Pooya, Lorna Myers, Kette Valente, Tyson Sawchuk, Anilu Daza Restrepo, Maryam Homayoun, Jeffrey Buchhalter, Zahra Bahrami, Firas Taha, Lorraine M Lazar, Angélica Aroni Paytan, Luciana D' Alessio, Silvia Kochen, Rudá Alessi, Susannah Pick, Timothy R Nicholson
PURPOSE: We compared various clinical characteristics of pediatric-onset psychogenic nonepileptic seizures (PNES) between patients from five countries. The purpose of this study was to advance our understanding of pediatric-onset PNES cross-culturally. METHODS: In this retrospective study, we compared consecutive patients with PNES with an age at onset of 16 years and younger from epilepsy monitoring units in Iran, Brazil, the USA, Canada, and Venezuela. Age, gender, age at seizure onset, seizure semiology, predisposing factors, and video-EEG recordings of all patients were extracted...
June 12, 2019: Seizure: the Journal of the British Epilepsy Association
https://read.qxmd.com/read/31207394/valproate-decreases-vitamin-d-levels-in-pediatric-patients-with-epilepsy
#37
REVIEW
Zejun Xu, Xia Jing, Guizhou Li, Jieyu Sun, Hongli Guo, Yahui Hu, Fang Sun, Xiaoyi Wen, Feng Chen, Tengfei Wang, Xiao-Peng Lu
PURPOSE: To compare Vitamin D (Vit D) levels in children with epilepsy on valproate monotherapy with healthy controls. METHODS: A meta-analysis performed on articles identified from PubMed and Web of Science online databases evaluated using National Institute of Health National Heart, Lung, and Blood Institute Study Quality Assessment Tools. Subgroup analyses and publication bias assessments were also performed. RESULTS: Eleven publications were eligible based on inclusion/exclusion criteria for the meta-analysis...
June 11, 2019: Seizure: the Journal of the British Epilepsy Association
https://read.qxmd.com/read/31238195/clinical-features-of-campylobacter-associated-benign-convulsions-with-mild-gastroenteritis-compared-with-rotavirus-convulsions
#38
Hui Chen, Jian Zha, Jian Min Zhong, Yong Chen, Xiong Ying Yu, Ji Hua Xie
PURPOSE: The aim of the present study was to compare the clinical features of campylobacter-associated benign convulsions with mild gastroenteritis (BCWG) with rotavirus-associated BCWG in China. METHODS: The medical records of BCWG patients admitted to Children's Hospital of Jiangxi Province in China between January 2015 and January 2017 were reviewed in this retrospective study. RESULTS: Ultimately, 318 patients were diagnosed with BCWG...
June 10, 2019: Seizure: the Journal of the British Epilepsy Association
https://read.qxmd.com/read/31207392/the-effect-of-early-midazolam-infusion-on-the-duration-of-pediatric-status-epilepticus-patients
#39
Emel Ulusoy, Murat Duman, Hüsne Didem Türker, Aykut Çağlar, Anıl Er, Fatma Akgül, Hale Çitlenbik, Ali Öztürk, Durgül Yılmaz
PURPOSE: Status epilepticus is one of the most common neurological emergencies in pediatric emergency departments. Although there are different approaches to treatment in the literature, early control of seizure activity is the most important factor determining prognosis. The purpose of this study was to evaluate the effect of early midazolam infusion on seizure duration. METHOD: This retrospective study included 150 episodes of 135 patients aged one month to 18 years old with status epilepticus...
June 10, 2019: Seizure: the Journal of the British Epilepsy Association
https://read.qxmd.com/read/31203026/supporting-and-empowering-people-with-epilepsy-contribution-of-the-epilepsy-specialist-nurses-sense-study
#40
Agnes Higgins, Carmel Downes, Jarleth Varley, Colin P Doherty, Cecily Begley, Naomi Elliott
PURPOSE: To explore how Epilepsy Specialist Nurses in the Republic of Ireland enacted their clinical role. METHODS: Qualitative descriptive design that involved individual and focus group interviews, observation and documentary analysis. Data were collected from 12 Epilepsy Specialist Nurses working in five hospital-based epilepsy services in Ireland, 24 multidisciplinary team members, and 35 people with epilepsy and their family members were involved. Data were analysed in NVivo using an inductive and deductive approach...
June 10, 2019: Seizure: the Journal of the British Epilepsy Association
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