Freda Scheffler, Jonathan Ipser, Devarshi Pancholi, Alistair Murphy, Zhipeng Cao, Jonatan Ottino-González, Paul M Thompson, Steve Shoptaw, Patricia Conrod, Scott Mackey, Hugh Garavan, Dan J Stein
BACKGROUND AND AIMS: The brain age gap (BAG), calculated as the difference between a machine learning model-based predicted brain age and chronological age, has been increasingly investigated in psychiatric disorders. Tobacco and alcohol use are associated with increased BAG; however, no studies have compared global and regional BAG across substances other than alcohol and tobacco. This study aimed to compare global and regional estimates of brain age in individuals with substance use disorders and healthy controls...
August 21, 2024: Addiction