European Journal of Cancer Care | Page 2

Lynnette M Jones, Lee Stoner, J Chris Baldi, Blair McLaren
OBJECTIVE: Cardiovascular disease is the leading cause of death in breast cancer survivors. While evidence shows circuit resistance training (CRT) is effective for improving muscle and cardiorespiratory fitness, whether CRT is an efficacious therapy for decreasing cardiovascular risk in cancer survivors is unclear. METHODS: Fifty-one breast cancer survivors were recruited to either 12 weeks CRT (n = 26), or a non-exercising wait-list control (n = 25). Two supervised 60 min CRT sessions per week were undertaken, comprising resistance and functional exercises, and aerobic exercise stations...
February 5, 2020: European Journal of Cancer Care
Humara Adnan, Sheikh Muhammad Adnan, Kui Deng, Chunyan Yang, Yan Hou, Victorine Raïssa Ngo Nkondjock, Kang Li
OBJECTIVE: Cancer patients exhibit disparity in mortality risks across demographic divisions as well as insurance groups. The effects of macroeconomic environment also vary for such strata. This study analyses the gaps between mortality risks for male and female cancer patients with and without insurance and examines how such gaps transform over time with macroeconomic shifts. METHODS: Demographic, clinical and treatment records of 45,750 melanoma and 91,157 lung cancer patients diagnosed in 2007-2009 and 2011-2013 were extracted from Surveillance, Epidemiology and End Results (SEER) database...
February 3, 2020: European Journal of Cancer Care
Christina M Stapelfeldt, Saskia F A Duijts, Trine A Horsboel, Anne-Mette H Momsen, Niels T Andersen, Finn B Larsen, Karina Friis, Claus V Nielsen
OBJECTIVES: To study whether educational attainment had less impact on work disability in cancer survivors than in individuals without cancer. To study whether comorbidity had a higher impact on work disability in low-educated cancer survivors than in high-educated and whether this impact differed when compared with individuals without cancer. METHODS: Linkage of population-based public health survey data and the Danish Cancer Registry formed two groups: cancer survivors (n = 3,514) and cancer-free individuals (n = 171,262)...
January 30, 2020: European Journal of Cancer Care
Chunfeng Wang, Jingyi Chen, Ying Wang, Rong Hu, Yong Wu
OBJECTIVE: To develop a communication prompt based on dignity therapy to facilitate effective conversations between patients with haematologic neoplasms and their family caregivers and to improve the programme and preliminarily explore the benefits and challenges of family participatory dignity therapy (FPDT). METHODS: A mixed-methods approach was applied to develop and revise the programme. The FPDT was developed and validated using the Delphi survey, and its further improvement was explored with a simple one-group pre- and post-trial and semi-structured in-depth interviews...
January 24, 2020: European Journal of Cancer Care
Ji-Su Kim, Ran Lee, Minhae Kim, Yeji Seo
OBJECTIVE: To identify oncology nurses' level of knowledge and awareness of metabolic syndrome (MetS) in cancer survivors and the perceived barriers to the provision of MetS-related care. METHODS: In this mixed-method study, 196 participants responded to a structured modified questionnaire that included items pertaining to MetS-related knowledge and awareness. Concurrently, 24 semi-structured interviews were conducted. A qualitative survey and quantitative interview were conducted between October 2018 and December 2018...
January 23, 2020: European Journal of Cancer Care
Haiying Ding, Xiaowei Zheng, Sisi Kong, Liyan Gong, Qunfang Ding, Ping Huang
OBJECTIVE: This study aims to investigate the impact of intervention of multidisciplinary team incorporating pharmacists for management of opioid-naïve patients with moderate to severe cancer pain. METHODS: A retrospective cohort study was conducted to compare pre- and post-multidisciplinary intervention groups in opioid-naïve patients with moderate to severe cancer pain. Primary outcome was the proportions of appropriate pain assessment and opioid titration. Secondary outcomes were pain intensity (PI), length of hospital stay, opioid escalation index percentage (OEI%) and incidences of opioid-related adverse events...
January 23, 2020: European Journal of Cancer Care
Sabine Schmid, Jorune Suipyte, Christian Herrmann, Mohsen Mousavi, Felicitas Hitz, Martin Früh
OBJECTIVE: Treatment options for non-small-cell lung cancer (NSCLC) have been evolving. The goal of our study was to evaluate whether novel therapeutics are used in the elderly population and improve outcomes to a similar extent as in young patients. METHODS: We enrolled patients registered in the Cancer Registry of Eastern Switzerland and grouped them into four cohorts: Elderly patients aged ≥70 years diagnosed 2005-2007 and 2015-2016 (elderly cohorts 1,2) were compared to cohorts of patients < 70 years diagnosed during the same time periods (young cohorts 1,2)...
January 21, 2020: European Journal of Cancer Care
Esther Baumann, Katharina Kuba, Heide Götze, Anja Mehnert-Theuerkauf, Peter Esser
OBJECTIVE: To date, no German instrument exists to assess subjective levels of cancer-related cognitive impairments (CRCI) in cancer survivors. We translated the validated Attentional Function Index (AFI) into German and explored its psychometric properties. METHODS: The validation sample consisted of 1,111 haematological cancer survivors mainly recruited from two cancer registries. Factorial structure was explored using principal component analysis, internal consistency via Cronbach's α, construct validity through correlational analyses (Pearson's r) and associations of patient characteristics with the AFI score via regression analyses...
January 20, 2020: European Journal of Cancer Care
Giada Danesi, Céline Bourquin, Friedrich Stiefel, Khalil Zaman, Michael Saraga
No abstract text is available yet for this article.
January 20, 2020: European Journal of Cancer Care
Lynn Calman, Eloise Radcliffe, Richard Berman, Sara Demain, Susan Restorick-Banks, Alison Richardson, Richard Wagland, Claire Foster
OBJECTIVE: Attention is turning to the needs of people living with treatable but incurable cancer, a group with complex needs, living with uncertainty over time. More research is needed to understand how this group self-manage the impact of cancer to strengthen the evidence base for interventions. This study aims to understand the value and outcomes of self-management support for people living with treatable but incurable cancer. METHODS: Qualitative longitudinal methods will examine how support needs change over time in relation to self-management and unpredictable disease trajectories...
January 20, 2020: European Journal of Cancer Care
Camilla Sødequist, Susanne S Pedersen, Ann Bøcher Secher Banke, Nina Rottmann
OBJECTIVE: Herceptin treatment improves survival and reduces the risk of recurrence in human epidermal growth factor receptor 2 (HER2)-positive breast cancer. Yet, it increases women's risk of developing burdensome cardiovascular complications. This study examines how women experience living with HER2-positive breast cancer and the risk of incident heart disease. METHODS: Danish women with breast cancer (n = 12; aged 32-75) participated in semi-structured interviews...
January 17, 2020: European Journal of Cancer Care
Emmanouil Kalampokas, Graham Macdonald, Helena Young, Antonina Bednarek, Ann-Marie Kennedy, Mary Cairns, David E Parkin
PURPOSE: To assess the recurrence pattern and survival in women treated with definitive chemoradiotherapy for cervical cancer. METHODS: A retrospective cohort study of women FIGO (2012) stage IB2 to IVA from the Grampian region of Scotland between February 2000 and March 2011. These women were followed up until April 2018. RESULTS: A total of 121 eligible women allocated with mean age at treatment 50.59 years (SD = 13.98, range 22-82). Tumours staged: IB2: n = 24 (19...
January 15, 2020: European Journal of Cancer Care
Laura Keaver, Helen Callaghan, Leah Walsh, Christine Houlihan
OBJECTIVE: To determine availability of nutrition information for cancer patients and survivors from Irish healthcare organisations, cancer charity and support groups and assess its quality and readability. DESIGN: Cross-sectional. SETTING: The National Health Service Executive websites were searched, as were the sites of the ten largest cancer charities/support groups identified through the Benefacts website. An additional internet search was conducted to ensure no large organisations/support groups were missed (February 2019)...
January 15, 2020: European Journal of Cancer Care
Ying Chen, Huimin Xiao, Jianwei Zheng, Xiaoling Zhang, Xiaoyan Lin
OBJECTIVES: To evaluate the effects of a mind map-based life review programme (MBLRP) on psychological distress, hope, meaning in life and self-transcendence in cancer patients undergoing chemotherapy. METHODS: Eighty-four cancer patients undergoing chemotherapy from a university-affiliated hospital in Fujian, China. The participants were randomly allocated to a MBLRP group (n = 40) or usual care group (n = 44). Data were collected at baseline (T0), on the second day (T1) and four weeks after the programme (T2) using the Distress Thermometer, Meaning in Life Questionnaire, Herth Hope Scale and Self-transcendence Scale...
January 7, 2020: European Journal of Cancer Care
Karin Bagni, Inna M Chen, Astrid Z Johansen, Christian Dehlendorff, Benny V Jensen, Carsten P Hansen, Jane Preus Hasselby, Niels H Holländer, Mette Nissen, Jon K Bjerregaard, Per Pfeiffer, Mette K Yilmaz, Louise S Rasmussen, Svend E Nielsen, Julia S Johansen
OBJECTIVES: Few studies have evaluated the impact of risk factors and comorbidity on overall survival (OS) in patients with pancreatic ductal adenocarcinoma (PDAC). The aim was to investigate the prognostic importance of Charlson's age-comorbidity index (CACI) and other risk factors on prognosis in a clinical real-world cohort of PDAC patients. METHODS: A total of 1,159 patients with PDAC who had received at least one cycle of adjuvant or palliative chemotherapy were included from the Danish BIOPAC study...
January 6, 2020: European Journal of Cancer Care
Flavia Faccio, Eleonora Mascheroni, Chiara Ionio, Gabriella Pravettoni, Fedro Alessandro Peccatori, Camilla Pisoni, Chiara Cassani, Sara Zambelli, Anna Zilioli, Giuseppe Nastasi, Nicola Giuntini, Lucia Bonassi
OBJECTIVE: Little is known about the process of becoming a mother in women who experienced a breast cancer diagnosis (BC). In this qualitative study, we investigated maternal representations in pregnant women with experience of BC and those with no oncological history. METHODS: A total of 38 women were recruited, 19 women who experienced a BC diagnosis and 19 who had not. To explore maternal representations, semi-structured interviews were conducted and analysed through thematic analysis...
January 6, 2020: European Journal of Cancer Care
Laura Cramond, Ian Fletcher, Claire Rehan
BACKGROUND: Compassion fatigue refers to the emotional and physical exhaustion felt by professionals in caring roles, whereas compassion satisfaction encompasses the positive aspects of helping others. Levels of compassion satisfaction and fatigue have been found to be inconsistent in palliative care professionals, which could have serious implications for patients, professionals and organisations. OBJECTIVES: This study explored the experiences of clinical psychologists working in palliative care, all worked with adults with cancer, to gain an understanding of the impact this work has on their self and how they manage this...
January 5, 2020: European Journal of Cancer Care
Emma G Hainsworth, Maryam Shahmanesh, Fiona Stevenson
OBJECTIVE: An increasing number of people living with HIV are living longer and experiencing a dual diagnosis of HIV and cancer. Little is known of their experience and quality of care. This paper presents the findings of a study exploring experiences of cancer care, from the perspectives of both patients and healthcare professionals. METHODS: Thematic analysis of participant narratives provided in longitudinal, semi-structured interviews with 17 people, recruited from three London sites between 2015 and 2017...
January 5, 2020: European Journal of Cancer Care
Vanessa Innao, Alessandro Allegra, Nicolina Pulvirenti, Andrea Gaetano Allegra, Caterina Musolino
BACKGROUND: The importance of the role of MicroRNAs (or miRNAs) has been emphasised by the large number of studies in human tumour cells, underlining the high impact of post-transcriptional processes in cancer onset, progression, invasion and metastatisation. Currently known as oncomiR, real databases are collecting all the smaller fragments of RNA capable of participating in the oncogenesis. AIMS: With the aim to collect for the first time the most important acquisitions in literature about antagomiRs in oncology, our narrative review is born with the purpose of showing that specific antisense oligonucleotides, capable to bind and antagonise single or multiple miRNAs, are effective as therapeutic compounds...
January 3, 2020: European Journal of Cancer Care
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