journal
https://read.qxmd.com/read/38595198/understanding-patterns-of-preserved-retinal-ganglion-cell-layer-in-advanced-glaucoma-as-seen-with-oct
#1
JOURNAL ARTICLE
Anna J Sun, Gabriel Gomide, Emmanouil Tsamis, Grace Mao, Ari Leshno, Sol La Bruna, Jeffrey M Liebmann, Gustavo De Moraes, Donald C Hood
PRECIS: Using OCT, eyes with advanced glaucoma were found to have a wide range of patterns of damage that were consistent with the natural history of progression based upon a model of macular progression. PURPOSE: To understand the patterns of preserved retinal ganglion cells in eyes with advanced glaucoma using OCT and a model of progression of the central macula. METHODS: OCT GCL thickness was measured in 94 eyes with advanced glaucoma, defined as glaucomatous eyes with a 24-2 MD (mean deviation) worse than -12 dB...
April 10, 2024: Journal of Glaucoma
https://read.qxmd.com/read/38595156/repeatability-of-online-circular-contrast-perimetry-compared-to-standard-automated-perimetry
#2
JOURNAL ARTICLE
Joshua Meyerov, Yang Chen, Lazar Busija, Catherine Green, Simon E Skalicky
PRCIS: Online circular contrast perimetry has good test repeatability and reliability that is comparable with standard automated perimetry. It holds promise for use in disease screening and surveillance to expand the provision of glaucoma care. PURPOSE: To evaluate the repeatability of online circular contrast perimetry (OCCP) compared to standard automated perimetry (SAP) in normal participants and patients with stable glaucoma over 18 weeks. METHODS: Thirty-six participants (13 normal controls and 23 patients with open angle glaucoma) were recruited...
April 10, 2024: Journal of Glaucoma
https://read.qxmd.com/read/38595151/breaking-barriers-in-behavioral-change-the-potential-of-ai-driven-motivational-interviewing
#3
JOURNAL ARTICLE
Areeba Abid, Sally L Baxter
Patient outcomes in ophthalmology are greatly influenced by adherence and patient participation, which can be particularly challenging in diseases like glaucoma where medication regimens can be complex. A well-studied and evidence-based intervention for behavioral change is Motivational Interviewing (MI), a collaborative and patient-centered counseling approach, which has been shown to improve medication adherence in glaucoma patients. However, there are many barriers to clinicians being able to provide motivational interviewing in-office, including short visit durations within high-volume ophthalmology clinics and inadequate billing structures for counseling...
April 10, 2024: Journal of Glaucoma
https://read.qxmd.com/read/38587450/the-pocket-technique-a-novel-surgical-technique-for-repair-of-glaucoma-drainage-device-tube-exposure
#4
JOURNAL ARTICLE
Tomas Mariano Grippo, Naomi E Gutkind, Carla Salina Indovinos, Matias Jesus Lopez Tomasella, Justina Candelaria Mutti, Agustina Limay Mena, Nicolas Monteros Alvi, Fernando Mayorga
Exposure of glaucoma tube shunts is an uncommon post-operative complication which poses a significant risk to the patient and may be difficult to repair. In this case series, the authors present two cases utilizing a novel surgical technique, the "pocket" technique, to place a scleral patch graft to address tube exposure. Patient 1 remained free of tube exposure at most recent follow up visit after 21 months, and patient 2 remained free of tube exposure at most recent follow up visit after 4 months. This technique offers an elegant surgical option that has multiple benefits; It allows for stability of the scleral patch graft even in cases of scarred down, thinned conjunctiva with minimal Tenons, allows for repair along the entire length of the tube shunt including perilimbal exposures, and allows for secondary healing when there is not enough conjunctiva to cover both the opening and the patch...
April 9, 2024: Journal of Glaucoma
https://read.qxmd.com/read/38587449/a-prospective-comparison-of-180-versus-360-degree-gonioscopy-assisted-transluminal-trabeculotomy-outcomes-in-pseudoexfoliation-glaucoma
#5
JOURNAL ARTICLE
Murat Gunay, Irem Berfu Cigiltepe, Adem Turk, Dilek Uzlu, Busra Kose
PRECIS: Analysis of surgical success and intraocular pressure (IOP), best-corrected visual acuity (BCVA) and antiglaucomatous medication (AGM) changes between segmental 180-degree and 360-degree gonioscopy-assisted transluminal trabeculectomy (GATT) in patients with pseudoexfoliation glaucoma (PEXG) showed no significant difference. PURPOSE: To compare surgical outcomes of segmental 180-degree and 360-degree GATT in PEXG patients. MATERIALS AND METHODS: Prospective, comparative study of 65 PEXG eyes, who underwent segmental 180-degree GATT (GATT 180° group, 31 eyes) and 360-degree GATT (GATT 360° group, 34 eyes) in a tertiary academic center over a 12-month of follow-up...
April 9, 2024: Journal of Glaucoma
https://read.qxmd.com/read/38573956/missed-opportunities-in-screening-for-glaucoma
#6
JOURNAL ARTICLE
Anja Tuulonen, Sanna Leinonen, Gauti Jóhannesson
PURPOSE: To create a holistic and realistic view regarding current knowledge, understanding, and challenges of screening in general and in glaucoma. METHODS/RESULTS: Based upon available literature, all systems suffer from the same challenges: huge variability of care practices (despite guidelines), simultaneous under-care and over-care, as well as the unsustainable increase of costs. While the magnitude of these challenges differs immoderately between well-off and developing countries, the Western world has already demonstrated that simply doing more than what we currently do is not the solution...
April 5, 2024: Journal of Glaucoma
https://read.qxmd.com/read/38573908/zonulopathy-and-its-relation-to-primary-angle-closure-disease-a-narrative-review
#7
JOURNAL ARTICLE
Jie Huang, Chukai Huang
UNLABELLED: The increasing lens vault (LV) and lens thickness (LT) is a recognized mechanism for primary angle closure glaucoma (PACG). Zonulopathy, causing the abnormal lens position, is an important factor in this mechanism. Several anatomically distinct sets of zonular fibers are present in primate eyes, including ciliary zonules, vitreous zonules and attachments between the posterior insertion zone of the vitreous zonules and the posterior lens equator (PVZ INS-LE strands). Zonulopathy, as a clinical diagnosis, exhibits zonular laxity and loss, long anterior lens zonules (LAZ)...
April 5, 2024: Journal of Glaucoma
https://read.qxmd.com/read/38573897/the-effect-of-phacoemulsification-on-the-intraocular-pressure-of-patients-with-open-angle-glaucoma-a-systematic-review-and-meta-analysis
#8
JOURNAL ARTICLE
Konstantinos Benekos, Andreas Katsanos, Anna-Bettina Haidich, Anna Dastiridou, Anna Nikolaidou, Anastasios G Konstas
PRECIS: There is evidence that cataract surgery can reduce intraocular pressure in patients with primary open angle-, normal tension-, or exfoliative glaucoma. The complete effect of phacoemulsification is masked by topical intraocular pressure-lowering medications. PURPOSE: To assess the impact of phacoemulsification and intraocular lens implantation on intraocular pressure (IOP) level in individuals with primary open-angle glaucoma (POAG), exfoliative glaucoma (XFG), exfoliation syndrome (XFS), normal tension glaucoma (NTG), ocular hypertension (OH) or healthy controls 12 months after the surgery...
April 5, 2024: Journal of Glaucoma
https://read.qxmd.com/read/38573889/social-determinants-of-health-and-glaucoma-screening-and-detection-in-the-sight-studies
#9
JOURNAL ARTICLE
Paula Anne Newman-Casey, Lisa A Hark, Ming-Chen Lu, Van Thi Ha Nghiem, Thomas Swain, Gerald McGwin, Saloni Sapru, Christopher Girkin, Cynthia Owsley
PURPOSE: To describe the neighborhood-level social risk factors across the three SIGHT Study sites and assess potential characteristics of these populations to help other researchers effectively design and implement targeted glaucoma community-based screening and follow-up programs in high-risk groups. METHODS/RESULTS: In 2019, Columbia University, University of Michigan, and University of Alabama at Birmingham each received 5 years of CDC funding to test a wide spectrum of targeted telehealth delivery methods to detect glaucoma in community-based health delivery settings among high-risk populations...
April 5, 2024: Journal of Glaucoma
https://read.qxmd.com/read/38557952/the-efficacy-of-fibrin-sealant-in-sutureless-deep-sclerectomy-preliminary-outcomes
#10
JOURNAL ARTICLE
Alina-Dana Baxant, Martin Pencak, Jana Vranova, Magdalena Netukova, Katarina Urbaniova, Lucie Holubova, Patrik Pluhovsky, Jozef Rosina, Pavel Studeny
PRCIS: Deep sclerectomy with fibrin adhesive can constitute a safe alternative to the classic procedure using sutures, providing non-allergenic, non-toxic and secure adhesion with no sign of aqueous humor outflow obstruction postoperatively. PURPOSE: To evaluate short- and medium-term postoperative results of deep sclerectomy (DS) with a fibrin sealant. PATIENTS AND METHODS: This prospective, noncomparative, interventional case-series involves 12 eyes of 12 patients with uncontrolled open-angle glaucoma (OAG) who underwent DS with Esnoper (Clip or V2000) implant between February 2021 and March 2022...
April 1, 2024: Journal of Glaucoma
https://read.qxmd.com/read/38551403/proportion-of-angle-closure-glaucoma-in-tamale-ghana
#11
JOURNAL ARTICLE
Catherine K Liu, Omair Ali, Ian Murdoch, Judith Simon
PRCIS: In the largest clinic-based study to date, our review of 588 patients presenting with glaucoma in Northern Ghana revealed 36% of these had primary angle closure glaucoma. PURPOSE: Glaucoma is the second leading cause of blindness worldwide. In Africa, glaucoma is an established public health problem, and primary angle-closure glaucoma (PACG) is not commonly discussed. Recognizing it is important because of its negative impact on visual morbidity, and also because its treatment is different from primary open angle glaucoma (POAG)...
April 1, 2024: Journal of Glaucoma
https://read.qxmd.com/read/38546234/recognition-of-glaucomatous-fundus-images-using-machine-learning-methods-based-on-optic-nerve-head-topographic-features
#12
JOURNAL ARTICLE
Chao-Wei Wu, Tzu-Yu Huang, Yeong-Cheng Liou, Shih-Hsin Chen, Kwou-Yeung Wu, Han-Yi Tseng
PURPOSE: The aim was to compare the effectiveness of clinical discriminant rules and machine learning classifiers in identifying glaucomatous fundus images based on optic disc topographic features. DESIGN: Retrospective case-control study. METHODS: The study used a total of 800 fundus images, half of which were glaucomatous cases and the other half non- glaucomatous cases obtained from an open database and clinical work. The images were randomly divided into training and testing sets with equal numbers of glaucomatous and non-glaucomatous images...
March 29, 2024: Journal of Glaucoma
https://read.qxmd.com/read/38546240/optical-coherence-tomography-versus-optic-disc-photo-assessment-in-glaucoma-screening
#13
JOURNAL ARTICLE
Luiz Arthur F Beniz, Veronica P Campos, Felipe A Medeiros
PURPOSE: This review article examines the strengths and limitations of optical coherence tomography (OCT) and optic disc photography in glaucoma screening. METHODS/RESULTS: A comprehensive literature review was conducted, focusing on the accuracy, feasibility, cost-effectiveness, and technological advancements in OCT and optic disc photography for glaucoma screening. OCT is highly accurate and reproducible but faces limitations due to its cost and less portable nature, making widespread screening challenging...
March 28, 2024: Journal of Glaucoma
https://read.qxmd.com/read/38546238/intraluminal-suture-placement-for-management-of-hypotony-after-glaucoma-drainage-device-surgery
#14
JOURNAL ARTICLE
Minjia Tang, Anupama R Anchala, Angelo P Tanna
PRCIS: Intraluminal 3-0 Supramid stent placement can be an effective long-term solution for hypotony after glaucoma drainage device surgery. This procedure may obviate the need for conjunctival dissection. In some cases, additional procedures are required. PURPOSE: To describe the utility of implantation of a multifilament polyamide suture (Supramid) in the tube lumen to reverse hypotony after glaucoma drainage device (GDD) surgery. PATIENTS: Patients who underwent tube revision with intraluminal placement of a 3-0 Supramid stent, with or without external ligature, to manage hypotony following GDD surgery between January 2010-October 2020...
March 28, 2024: Journal of Glaucoma
https://read.qxmd.com/read/38536150/screening-for-glaucoma-is-challenging-but-should-be-actively-pursued
#15
JOURNAL ARTICLE
David Friedman
No abstract text is available yet for this article.
March 28, 2024: Journal of Glaucoma
https://read.qxmd.com/read/38536128/drug-induced-liver-injury-during-a-glaucoma-neuroprotection-clinical-trial
#16
JOURNAL ARTICLE
Aakriti Garg Shukla, George A Cioffi, Jeffrey M Liebmann
There are several ongoing, worldwide clinical trials with a cumulative target enrollment of over 1300 participants on the role of nicotinamide (a specific form of vitamin B3) as a therapeutic neuroprotective treatment for glaucoma. We describe a serious adverse event of drug-induced liver injury (DILI) likely related to the use of 3 grams/day nicotinamide in a glaucoma clinical trial (clinicaltrials.gov identifier: NCT05695027) based in the United States. This report is important to share with the medical community, as other participants in glaucoma nicotinamide trials globally may have similar adverse events and many patients are using nicotinamide as a health supplement without medical supervision...
March 28, 2024: Journal of Glaucoma
https://read.qxmd.com/read/38536124/metformin-in-glaucoma-treatment
#17
JOURNAL ARTICLE
Qëndresë Daka, Burim Neziri, Ewald Lindner, Augusto Azuara Blanco
PURPOSE: The objective of this study was to evaluate the potential beneficial impact of metformin on glaucoma risk factors and explore the underlying mechanisms. The goal is to contribute to the development of novel treatment strategies for glaucoma. METHODS: We searched for studies that assessed the effects of metformin on glaucoma risk factors and the associated underlying mechanisms. Our search included electronic databases such as PUBMED, EMBASE, and clinicaltrials...
March 28, 2024: Journal of Glaucoma
https://read.qxmd.com/read/38536121/glaucoma-screening-in-the-primary-care-setting-practical-and-innovative-approaches
#18
JOURNAL ARTICLE
Aakriti Garg Shukla, George A Cioffi
No abstract text is available yet for this article.
March 28, 2024: Journal of Glaucoma
https://read.qxmd.com/read/38536120/fixed-high-energy-versus-standard-titrated-energy-settings-for-selective-laser-trabeculoplasty
#19
JOURNAL ARTICLE
Sunayana N Murthy, Priyasha Goel, Suneeta Dubey, Monica Gandhi
No abstract text is available yet for this article.
March 28, 2024: Journal of Glaucoma
https://read.qxmd.com/read/38536115/obstacles-to-screening-today
#20
JOURNAL ARTICLE
Harry A Quigley
PURPOSE: To introduce a discussion of glaucoma screening. METHODS/RESULTS: Glaucoma screening faces challenges including not satisfying important ethical principles for medical screening. CONCLUSIONS: Approaches that would better provide care for glaucoma patients include eliminating loss to follow-up and identification of glaucoma among family members of known glaucoma patients.
March 28, 2024: Journal of Glaucoma
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