Journal of Glaucoma

PRCIS: In this case-control study of the Japanese population, including 3207 glaucoma cases, alcohol consumption patterns such as frequency and quantity showed a positive association with glaucoma prevalence. PURPOSE: To examine the association between alcohol consumption patterns and glaucoma. PATIENTS AND METHODS: This case-control study evaluated 3207 cases with glaucoma and 3207 matched controls. Patients over 40 years of age were included from 1,693,611 patients admitted to 34 hospitals in Japan...

PRECIS: Biometric parameters, including binocular difference of anterior chamber depth, lens vault in affected eyes, and binocular difference of lens vault, had high efficiency in diagnosing acute angle closure with zonular laxity. PURPOSE: To investigate the ocular biometric characteristics of eyes with acute angle closure (AAC) with zonular laxity to further explore the sensitive parameters for preoperative diagnosis. METHODS: This study included 50 AAC patients with zonular laxity and 54 AAC patients without zonular laxity...

PRCIS: Capillary and neuronal tissue loss occur both globally and with regional specificity in pre-perimetric glaucoma patients at the level of the optic nerve and macula, with perifovea regions affected earlier than parafovea areas. PURPOSE: To investigate optic nerve head (ONH) and macular vessel densities (VD) and structural parameters assessed by optical coherence tomography angiography (OCTA) in pre-perimetric open-angle glaucoma (ppOAG) patients and healthy controls...

PRCIS: Use of the Ocular Response Analyzer (ORA) as a screening tonometer in clinical practice yielded reliable measurements in over 80% of eyes screened. Including corneal hysteresis (CH) data in screening may improve the accuracy of glaucoma detection. PURPOSE: To examine measurement reliability when the ORA is used as a screening tonometer, and to compare CH measurements in eyes with and those without glaucomatous changes in the fundus. PATIENTS AND METHODS: 1488 eyes of 747 patients (mean age: 53...

PRECIS: Juvenile open-angle glaucoma patients with thick central corneas and negative family history were more likely to undergo surgery, mainly trabeculectomy with half requiring additional surgery within 10 years. PURPOSE: To assess the characteristics and treatment outcomes of patients with juvenile open-angle glaucoma (JOAG) in Thailand. METHOD: This retrospective, multicenter study included all patients diagnosed with JOAG over 12 years from two tertiary hospitals in Bangkok, Thailand...

PRCIS: Significant reductions in IOP and number of medications are sustained up to 6 years postoperatively for eyes that underwent ab-interno canaloplasty using the iTrack microcatheter, either as a standalone procedure or combined with cataract surgery. PURPOSE: To evaluate the long-term effectiveness of iTrack (Nova Eye Medical, Inc.) ab-interno canaloplasty for reducing intraocular pressure (IOP) and number of glaucoma medications in patients with primary open-angle (POAG) and pseudoexfoliative (PEX) glaucoma...

PRECIS: XEN 45 Gel Stent is safe and effective for 3 years. The study results provide useful insight into the outcome of XEN 45 Gel Stent surgery over 5 years in daily clinical practice. PURPOSE: To evaluate 5-year outcomes of XEN 45 gel stent implantation (XEN) in patients with open-angle glaucoma. PATIENTS AND METHODS: This is a prospective, single-center, interventional study. XEN implantation either alone (XEN) or combined with phacoemulsification (Phaco + XEN) was performed on 170 consecutive eyes (126 patients) with uncontrolled intraocular pressure (IOP) or disease progression despite medical treatment...

PRCIS: Goniotomy is an alternative surgery for patients with prior failed surgery for glaucoma. PURPOSE: To evaluate the efficacy and safety of goniotomy (GT) in patients with prior failed surgery for glaucoma. MATERIALS AND METHODS: A prospective, observational multicentered study was performed for patients who underwent GT with prior single or multiple surgery for glaucoma. Outcome measures included intraocular pressure (IOP) change, best-corrected visual acuity (BCVA) change, ocular hypotensive medication use, and occurrence of adverse events through 12 months...

No abstract text is available yet for this article.

PRCIS: The current study highlights distinct choroidal alterations in primary open-angle and angle-closure glaucoma, underscoring the potential of choroidal vascularity index as a valuable indicator for understanding glaucoma pathogenesis. PURPOSE: To evaluate choroidal structural changes in patients with primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG) and healthy controls utilizing the choroidal vascularity index (CVI) and subfoveal choroidal thickness (SFCT) by enhanced depth imaging optical coherence tomography (EDI-OCT)...

No abstract text is available yet for this article.

PRECIS: In a diverse nationwide cohort, lower education and income levels, cost saving on medications, fewer past-year medical/specialist visits, and concerns regarding dissimilarity with healthcare providers were risk factors for ophthalmic visit non-adherence among glaucoma patients. PURPOSE: To characterize social and healthcare utilization factors associated with non-adherence with ophthalmic visits among patients with glaucoma. METHODS: Glaucoma patients in the All of Us database who completed the Healthcare Access and Utilization Survey were included and categorized into "visit" and "non-visit" groups based on visit adherence, defined by self-reported past-year encounters with eyecare providers (yes/no)...

PRCIS: Drive-through IOP measurement using iCare tonometry is a promising method of low-contact, high-throughput IOP monitoring. However, owing to its vulnerability to variable measurement technique and local air currents, the iCare may overestimate IOPs. PURPOSE: During the COVID-19 pandemic, a drive-through intraocular pressure (IOP) measurement protocol using the iCare tonometer was established to facilitate low-contact monitoring of select glaucoma patients...

PRCIS: The iCare HOME2 tonometer generally can be considered reliable for most eyes and clinical settings, although it may produce slightly overestimated or underestimated intraocular pressure readings in thicker and thinner corneas, respectively. PURPOSE: To evaluate the accuracy, correlation, and analysis of differences in intraocular pressure (IOP) measurements between the gold standard Goldmann applanation tonometer (GAT) and the new, self-measurement iCare HOME2 tonometer (icare, Vantaa, Finland)...

PRCIS: Transcorneal transillumination aided transscleral cyclophotocoagulation for intraocular pressure control of refractory pediatric glaucoma was found to be effective at 1 year. PURPOSE: To study one-year outcomes of diode laser transscleral cyclophotocoagulation (TSCPC) with trans-corneal transillumination using a novel low-cost torchlight method in refractory paediatric glaucoma. METHODS: This prospective interventional study included children with refractory glaucoma who underwent TSCPC with the Oculight® laser system (IRIS Medical Instruments) with trans-corneal transillumination (TSCPC-TI) using a novel low-cost torchlight method...

PRECIS: Primary trabeculectomy was safe and effective at lowering intraocular pressure in patients with primary open angle glaucoma and high myopia. PURPOSE: To investigate the efficacy and safety of trabeculectomy in patients with glaucoma and high myopia. PATIENT AND METHODS: Retrospective case control study. Glaucomatous patients with high myopia undergoing primary trabeculectomy surgery with at least one year of follow-up were compared to an age-matched control group without high myopia undergoing the same procedure...

PRCIS: Participant surveys taken after using tablet-based and smart visual function analyzer perimetry tests suggest that patients may prefer novel perimetry tests over traditional visual-field machines. PURPOSE: Compare patient experience using the IMOvifa smart visual function analyzer and the tablet-based Melbourne Rapid Fields visual field tests to the Humphrey Field 24-2 Swedish Interactive Threshold Algorithm Standard. PATIENTS AND METHODS: Prospective observational cohort study on adult participants with diagnoses of glaucoma suspect, ocular hypertension, or glaucoma...

PRCIS: There was a significant inverse linear relationship between age at menopause and open-angle glaucoma (OAG). Late menarche (≥13 y) and a history of 5 or more deliveries were significantly associated with increased risk of OAG. PURPOSE: To determine the association between reproductive factors including age at menarche, age at menopause, reproductive period, parity and the risk of open-angle glaucoma (OAG) in women. METHODS: PubMed, Embase, Cochrane Library and Web of Science were searched until February 9, 2022...

PRCIS: Among children with unilateral glaucoma associated with Sturge-Weber syndrome, 7 of 47 demonstrated involvement in the fellow eye, and that group had had earlier first-eye surgery relative to the non-involvement group. PURPOSE: To determine the incidence of and risk factors for fellow-eye involvement in children with unilateral Sturge-Weber Syndrome (SWS)-associated glaucoma. METHODS: Children diagnosed with unilateral facial port-wine stain (PWS) and ipsilateral glaucoma before the age of five and followed up for at least 5 years were enrolled...

PURPOSE: To analyze utilization rates of glaucoma surgeries and MIGS among United States Medicare beneficiaries between 2021-2022. DESIGN: Retrospective comparative analysis of 68,118 unique patients. METHODS: National claims data from a 5% sample of all Medicare beneficiaries were utilized to compare glaucoma procedure counts between the first quarter of 2021 and the first quarter of 2022. Duplicate claims were excluded, and 50 modifiers were counted as two distinct procedures...