Journals European Journal of Cancer Pre...

European Journal of Cancer Prevention
Jingya Liu, Yingchun Man, Jianing Gao, Xinxin Wang, Lijie Zhang, Mingheng Li, Jiahan Yu
OBJECTIVE: The objective of this study is to evaluate the correlation between tumor proportionality scores (TPS) and the effectiveness of immune checkpoint inhibitors (ICIs) as the second or subsequent line therapies for individuals who received diagnoses of advanced non-small cell lung cancer (NSCLC). METHODS: The retrospective analysis was conducted on the medical records of a total of 143 patients who received diagnoses of stage IIIB/IV NSCLC and were admitted to our hospital from the beginning of 2019 to the end of September 2022...
February 23, 2024: European Journal of Cancer Prevention
Jeanne M Ward, Frances Hardin-Fanning
OBJECTIVE: The objective of this study was toidentify and appraise available sun protection self-efficacy instruments and synthesize information. DATA SOURCE: A systematic search of electronic databases from 2005 to 2023 included PubMed, CINAHL, Embase and PsycINFO. BACKGROUND: While instruments have been developed to evaluate sun-protective behaviors and self-efficacy separately, sun-protection self-efficacy instruments have yet to be widely studied...
February 20, 2024: European Journal of Cancer Prevention
Soyeoun Kim, Thi Xuan Mai Tran, Mi Kyung Kim, Min Sung Chung, Eun Hye Lee, Woojoo Lee, Boyoung Park
BACKGROUND: We investigated the association between established risk factors for breast cancer and mammographic breast density in Korean women. METHODS: This large cross-sectional study included 8 460 928 women aged >40 years, who were screened for breast cancer between 2009 and 2018. Breast density was assessed using the Breast Imaging Reporting and Data System. This study used multiple logistic regression analyses of age, BMI, age at menarche, menopausal status, menopausal age, parity, breastfeeding status, oral contraceptive use, family history of breast cancer, physical activity, smoking, drinking and hormone replacement therapy use to investigate their associations with mammographic breast density...
February 20, 2024: European Journal of Cancer Prevention
Yong Zhu
OBJECTIVE: The incidence of neuroendocrine tumors (NET) has been increasing globally for several decades. The objective of the study was to examine the most recent trend in the incidence of NET as well as disparities by sex and race/ethnicity in adults in the USA. METHODS: Patients with NET aged ≥20 years were identified from the SEER 22 Registries from 2000 to 2020. The age-adjusted incidence rate was calculated for overall NET and by primary site...
February 20, 2024: European Journal of Cancer Prevention
Claudio Pelucchi, Carlo La Vecchia, Rossella Bonzi, Eva Negri, Giovanni Corso, Stefania Boccia, Paolo Boffetta, M Constanza Camargo, Maria Paula Curado, Nuno Lunet, Jesus Vioque, Zuo-Feng Zhang
We updated to December 2023 the main findings of the stomach cancer pooling (StoP) project including about 13 000 cases and 31 000 controls from 29 case-control and 5 nested studies. The StoP project quantified more precisely than previously available the positive associations of tobacco smoking, high alcohol consumption, meat intake, selected occupations (e.g. agricultural and miners), gastric ulcer and family history with gastric cancer and the inverse associations with socioeconomic status and selected aspects of diet (fruits, including citrus fruits, vegetables, including allium and mushrooms, and polyphenols)...
February 20, 2024: European Journal of Cancer Prevention
Junwei Sun, Mingyu Wang, Zhisheng Kan
BACKGROUND: We aimed to develop tools that could predict the occurrence of distant metastases in melanoma and its prognosis based on clinical and pathological characteristics. MATERIALS AND METHODS: We obtained data from the Surveillance, Epidemiology, and End Results (SEER) database of melanoma patients diagnosed between 2010 and 2019. Logistic analyses were performed to identify independent risk factors associated with distant metastasis. Additionally, multivariate Cox analyses were conducted to determine independent prognostic factors for patients with distant metastasis...
January 23, 2024: European Journal of Cancer Prevention
Hung N Luu, Yen Thi-Hai Pham, Jian-Min Yuan, Randall E Brand, Tuyen Van Pham, Hang Viet Dao, Chung Kim Thi Le, Nhi Yen Ngoc Huynh, Hai Minh Nguyen, Ngoan Tran Le
BACKGROUND: Pancreatic cancer is a leading cause of cancer-related death worldwide. Tryptophan plays a vital role in cell growth and maintenance as a building block of protein and coordination of organismal responses to environmental and dietary cues. Animal model study showed that dietary tryptophan improved treatment response in those who received chemotherapy or immune checkpoint inhibitors. Limited data are available assessing the association between tryptophan intake and risk of pancreatic cancer...
January 15, 2024: European Journal of Cancer Prevention
Yanyan Xu, Hao Che, Jiang Liu, Pingjiang Ye
BACKGROUND: Metformin and statins are commonly used globally for the treatment of type 2 diabetes mellitus and dyslipidemia, respectively. Recently, multiple novel pathways have been discovered, which may contribute to the treatment of various types of cancer. Several meta-analysis studies have reported that the use of metformin or statins is associated with a lower risk of colon cancer compared to nonusers. In this study, our aim was to perform a meta-analysis and investigate the prognostic roles of these two medications in colon cancer...
January 15, 2024: European Journal of Cancer Prevention
Alberto Puccini, Simone Nardin, Lucia Trevisan, Sonia Lastraioli, Viviana Gismondi, Ilaria Ricciotti, Azzurra Damiani, Giacomo Bregni, Roberto Murialdo, Alessandro Pastorino, Valentino Martelli, Annalice Gandini, Luca Mastracci, Liliana Varesco, Maria Dono, Linda Battistuzzi, Federica Grillo, Stefania Sciallero
BACKGROUND: Universal screening of colorectal cancer (CRC) patients for Lynch syndrome (LS) through MisMatch Repair (MMR) testing is recommended. BRAFV600E mutation and/or MLH1 promoter methylation (Reflex Testing, RefT)generally rule out LS in MLH1-deficient (dMLH1) patients. We estimated the impact of RefTon genetic counseling (GC) and on the diagnostic yield of genetic testing (GT). METHODS: Overall, 3199 CRC patients were referred to our center between 2011 and 2021...
January 9, 2024: European Journal of Cancer Prevention
Alaa Ahmed Elshanbary, Mohamed Sayed Zaazouee, Anas Zakarya Nourelden, Mohammed Al-Kafarna, Sajeda Ghassan Matar, Ahmed Saad Elsaeidy, Khaled Mohamed Ragab, Mahmoud M Elhady, Ghadeer M Albadrani, Ahmed E Altyar, Osama A Kensara, Mohamed M Abdel-Daim
BACKGROUND AND AIMS: Breast cancer is considered one of the most common neoplasms worldwide. Diabetes (DM) increases mortality among postmenopausal patients with breast cancer. Our study aims to identify the risk factors of DM-specific mortality and infiltrating ductal carcinoma (IDC) mortality in patients with IDC of the breast. MATERIALS AND METHODS: Data of IDC patients were obtained from the Surveillance, Epidemiology, and End Results database from 1975 to 2016...
December 27, 2023: European Journal of Cancer Prevention
Eliane Kellen, Zoi Meers, Lore Pil, Mathijs C Goossens
BACKGROUND: The total coverage of both the Flemish breast cancer and cervical screening program remain suboptimal, with approximately 63% for both. Of all the women invited to the breast cancer screening program, 14.1% never underwent any type of breast cancer screening (any type of mammogram, ultrasound, or clinical breast examination). For the cervical cancer screening, this proportion of 'never-screeners' is 12.1%. We conducted two randomized controlled trials to assess whether various communication and presentation styles in the invitation package, were effective at motivating women who had never participated to attend...
December 18, 2023: European Journal of Cancer Prevention
Alireza Bahrami, Karim Parastouei, Maryam Taghdir, Mojtaba Ghadyani
BACKGROUND: Regarding the role of insulin and insulin-inducing dietary factors in some cancers' etiology, we hypothesized that the risk of colorectal cancer may be lessened by following a lower carbohydrate and insulinogenic diet. Therefore, we performed this study to explore the association between a low-carbohydrate diet and insulin indices and the odds of colorectal cancer. METHOD: This hospital-based case-control study was conducted on 150 newly diagnosed colorectal cancer patients and 300 healthy age- and sex-matched hospitalized controls...
December 18, 2023: European Journal of Cancer Prevention
Guanhua Yu, Ran Wei, Hengchang Liu, Yixiao Liu, Xu Guan, Xishan Wang, Zheng Jiang
OBJECTIVES: Adjuvant chemotherapy benefits in elderly patients with stage II colon cancer (CC) remain controversial. We aimed to construct a nomogram to estimate the chemotherapy survival benefits in elderly patients. METHODS: The training and testing cohort were patients with stage II CC older than 70 years from the Surveillance, Epidemiology, and End Results (SEER) database, while the external validation cohort included patients from the National Cancer Center (NCC)...
March 1, 2024: European Journal of Cancer Prevention
Petra Kriķe, Meret Sophia Appel, Zakera Shums, Inese Poļaka, Ilona Kojalo, Dace Rudzīte, Ivars Tolmanis, Arnis Kiršners, Inga Bogdanova, Ilona Aleksandravica, Gary L Norman, Mārcis Leja
The role of autoimmunity in the pathogenesis of gastric cancer remains controversial. We studied antiparietal cell antibody (anti-PCA) and anti-intrinsic factor antibody (anti-IFA) levels and their associations with pepsinogen I/pepsinogen II levels in patients with gastric adenocarcinoma compared to a control group with mild or no atrophy of the stomach mucosa. Plasma levels of anti-PCA and anti-IFA were measured by ELISA (Inova Diagnostics Inc, San Diego, California, USA). The cutoff value for anti-PCA and anti-IFA positivity was ≥25 units...
January 1, 2024: European Journal of Cancer Prevention
Wenqiang Liao, Yuxiang Wang, Wenpeng Zhang
BACKGROUND: A meta-analysis was performed in this study to evaluate the association between serum uric acid and the risk of colorectal cancer (CRC). METHODS: Relevant observational studies observing the relationship between uric acid and the incidence of CRC were obtained by the search of electronic databases, including Medline, Embase, Cochrane Library and Web of Science . A randomized-effects model was selected to pool the data by incorporating the influence of potential heterogeneity...
January 1, 2024: European Journal of Cancer Prevention
Taja Lozar, Kyungmann Kim, Thomas C Havighurst, Gary S Wood, Jill M Kolesar, Howard H Bailey
BACKGROUND: Here we report clinical risk factors and event rates for the development of new non-melanoma skin cancer (NMSC) in a randomized, double-blind, placebo-controlled trial of the irreversible ornithine decarboxylase (ODC) inhibitor, difluromethylornithine (DFMO), over a 3-5-year follow-up. METHODS: 147 placebo patients (white; mean age 60.2 years; 60% male) were evaluated for event rates and association of initial skin biomarkers and baseline patient characteristics with the development of squamous cell (SCC) and basal cell (BCC) carcinomas...
January 1, 2024: European Journal of Cancer Prevention
Dominika Trojnarska, Robert Jach
OBJECTIVES: This study aimed to assess the knowledge of human papillomavirus (HPV) and attitudes toward HPV vaccination (HPVv) among female patients in Poland, investigating the impact of sociodemographic factors on these aspects. The study also explored awareness of state-funded bivalent vaccination and gauged willingness to vaccinate children, especially in the aspect of the newly introduced nonavalent vaccine. MATERIAL AND METHODS: An 11-question questionnaire was administered to newly referred patients at a dysplasia consultation center in Kraków University Hospital between February and December 2022...
November 30, 2023: European Journal of Cancer Prevention
Francesco Di Bello, Ernesto di Mauro, Giovanni Maria Fusco, Alfonso Falcone, Gabriele Pezone, Claudia Collà Ruvolo, Gianluigi Califano, Agostino Fraia, Francesco Passaro, Francesco Pepillo, Alessandro Ranieri, Pierluigi Alvino, Francesco Mastrangelo, Carmine Turco, Luigi Cirillo, Corrado Aniello Franzese, Roberto La Rocca, Massimiliano Creta, Nicola Longo, Luigi Napolitano
OBJECTIVE: To evaluate the quality of apps for prostate cancer antigen (PSA) dosage, available for downloading on the iOS and Android platforms, discussing the potential role of mobile health applications (MHAs) in update the screening protocol. METHODS: An observational cross-sectional descriptive study of all smartphone apps for PSA dosage was performed through the most used platforms (iOS and Android). On 10 February 2023, a total of 457 apps were found according to the search criteria...
November 30, 2023: European Journal of Cancer Prevention
Bowen Li, Xiaopeng Zhang
BACKGROUND: There is currently a shortage of effective diagnostic tools that are used for identifying long-term survival among non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations. This research utilized the development of a prognostic model to assist clinicians in forecasting the survival over 24 months. METHODS: In Phase III and IV those patients who were diagnosed with EGFR mutation from January 2018 to June 2022 were enrolled into the lung cancer group of Thoracic Surgery Department of Hebei Provincial People's Hospital...
November 28, 2023: European Journal of Cancer Prevention
Silvia Mignozzi, Claudia Santucci, Matteo Malvezzi, Fabio Levi, Carlo La Vecchia, Eva Negri
OBJECTIVE: Anal cancer is a rare disease, affecting more frequently women than men, mainly related to human papillomavirus infection (HPV). Rising incidence and mortality have been reported over the past four decades in different countries. METHODS: To provide an up-to-date overview of recent trends in mortality from anal cancer, we analysed death certification data provided by the WHO in selected countries worldwide over the period from 1994 to 2020. We also analysed incidence derived from Cancer Incidence in Five Continents from 1990 to 2012 for all histologies as well as for anal squamous cell carcinoma (SCC)...
November 27, 2023: European Journal of Cancer Prevention
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