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American Journal on Addictions

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https://read.qxmd.com/read/30901127/rapid-micro-induction-of-buprenorphine-naloxone-for-opioid-use-disorder-in-an-inpatient-setting-a-case-series
#1
Sukhpreet Klaire, Rebecca Zivanovic, Skye Pamela Barbic, Raman Sandhu, Nickie Mathew, Pouya Azar
BACKGROUND AND OBJECTIVES: Buprenorphine/naloxone has been shown to be effective in the treatment of opioid use disorder. Due to its pharmacological properties, induction can be challenging, time-consuming, and result in sudden onset of withdrawal symptoms. METHODS: Retrospective case series (n = 2). RESULTS: Two patients with opioid use disorder were successfully started on buprenorphine/naloxone using a rapid micro-induction technique that did not cause precipitated withdrawal or require preceding cessation of other opioids...
March 22, 2019: American Journal on Addictions
https://read.qxmd.com/read/30901123/brief-report-characterization-of-marijuana-use-in-us-college-students-by-state-marijuana-legalization-status-as-reported-to-an-online-survey
#2
George Sam Wang, Colleen Haynes, Andrea Besharat, Marie-Claire Le Lait, Jody L Green, Richard C Dart, Genie Roosevelt
BACKGROUND AND OBJECTIVE: US college student marijuana use is the highest since 1980. The objective was to investigate use characteristics among college students. METHODS: The RADARS® System College Survey Program surveyed individuals in a university, technical or online school. This was a secondary analysis of existing data. RESULTS: Seven thousand one hundred five students were enrolled, <30% of students' perceived marijuana use a health risk...
March 22, 2019: American Journal on Addictions
https://read.qxmd.com/read/30802344/the-potency-of-social-versus-drug-rewards
#3
(no author information available yet)
No abstract text is available yet for this article.
February 25, 2019: American Journal on Addictions
https://read.qxmd.com/read/30724428/the-castro-study-unsafe-sexual-behaviors-and-illicit-drug-use-among-gay-and-bisexual-men-who-use-anabolic-steroids
#4
Eric J Ip, Shadi Doroudgar, Bijal Shah-Manek, Mitchell J Barnett, Michael J Tenerowicz, Marvin Ortanez, Harrison G Pope
BACKGROUND AND OBJECTIVES: The majority of anabolic androgenic steroid (AAS) studies have focused on the general male population. Approximately 15% of gay or bisexual men are seropositive for HIV and many AASs are administered via injection. Thus, AAS use among gay and bisexual men likely poses a greater risk of spreading infectious disease. Gay and bisexual men who use AAS were compared with non-users regarding self-reported seropositivity for HIV and hepatitis B and C, sexual behaviors and injection practices, illicit drug and alcohol use, and psychiatric disorders...
February 6, 2019: American Journal on Addictions
https://read.qxmd.com/read/30701618/preclinical-efficacy-of-an-anti-methamphetamine-vaccine-using-e6020-adjuvant
#5
Reetakshi Arora, Colin N Haile, Therese A Kosten, Yan Wu, Muthu Ramakrishnan, Lynn D Hawkins, Frank M Orson, Thomas R Kosten
BACKGROUND AND OBJECTIVE: Methamphetamine (MA) substance use disorder (SUD) does not have an efficacious pharmacotherapy. We developed a MA vaccine and investigated its potential to attenuate MA induced responses. METHODS: We examined a novel adjuvant, E6020, a Toll-like receptor-4 (TLR-4) agonist combined with tetanus-toxoid conjugated to succinyl-methamphetamine (TT-SMA) adsorbed on aluminum hydroxide (alum). Adult BALB/c female mice received the vaccine and booster injections at weeks 0, 3, and 6...
January 31, 2019: American Journal on Addictions
https://read.qxmd.com/read/30701615/review-article-effective-management-of-opioid-withdrawal-symptoms-a-gateway-to-opioid-dependence-treatment
#6
REVIEW
Thomas R Kosten, Louis E Baxter
BACKGROUND AND OBJECTIVES: The opioid crisis has taken an immense toll in the United States. On average, five lives are lost to an opioid overdose every hour of the day; estimated costs associated with opioid misuse exceed $500 billion annually. Illicit opioid discontinuation is the first step in the treatment of opioid use disorder (OUD), and transition to an opioid agonist may initiate treatment. However, discontinuation to abstinence from either OUD directly or following agonist treatment results in severely distressing opioid withdrawal symptoms (OWS)...
January 31, 2019: American Journal on Addictions
https://read.qxmd.com/read/30701613/no-increased-pain-among-opioid-dependent-individuals-treated-with-extended-release-naltrexone-or-buprenorphine-naloxone-a-3-month-randomized-study-and-9-month-open-treatment-follow-up-study
#7
Zill-E-Huma Latif, Kristin K Solli, Arild Opheim, Nikolaj Kunoe, Jūratė Š Benth, Peter Krajci, Kamni Sharma-Haase, Lars Tanum
BACKGROUND AND OBJECTIVES: It is presently unclear whether extended-release naltrexone hydrochloride treatment induces pain or aggravates existing pain among individuals with opioid use disorders. We assessed changes in pain among individuals receiving treatment with either extended-release naltrexone hydrochloride or buprenorphine-naloxone hydrochloride. METHODS: This randomized prospective open-label clinical study included 143 participants (aged 18-60 years) with opioid dependencies, recruited from outpatient addiction clinics at five urban hospitals in Norway...
January 31, 2019: American Journal on Addictions
https://read.qxmd.com/read/30664303/impulsiveness-as-a-predictor-of-topiramate-response-for-cocaine-use-disorder
#8
Derek Blevins, Xin-Qun Wang, Sana Sharma, Nassima Ait-Daoud
BACKGROUND/OBJECTIVES: Topiramate has been studied in the treatment of substance use disorders and is often used off-label in the treatment of other disorders with impaired impulse control. We sought to determine whether impulsiveness could predict topiramate treatment response in individuals with cocaine use disorder (CUD). METHODS: In a post-hoc analysis of a 12-week, double-blind, randomized, placebo-controlled trial of topiramate for CUD, we examined the relationship between response to treatment and participants' baseline score on the Barrett Impulsiveness Scale (BIS-11)...
January 21, 2019: American Journal on Addictions
https://read.qxmd.com/read/30664299/buprenorphine-for-the-treatment-of-posttraumatic-stress-disorder
#9
Elizabeth P Lake, Brian G Mitchell, Darryl I Shorter, Thomas Kosten, Coreen B Domingo, Annette M Walder
BACKGROUND AND OBJECTIVES: The core pharmacological treatment of Post-Traumatic Stress Disorder (PTSD) is selective serotonin reuptake inhibitors (SSRIs), although remission is only around 30% with them. Many patients will self-treat with opioids and due to the opiate system involvement in dysphoric mood and anxiety/stress responses, it is likely that antagonism of the kappa opioid receptor (KOR) system represents a potential target for treatment of PTSD. The aim of this study is to compare response of PTSD symptoms when antagonizing KOR via buprenorphine/naloxone compared to SSRIs or opioid therapy...
January 21, 2019: American Journal on Addictions
https://read.qxmd.com/read/30664282/comparison-of-opioid-use-disorder-among-male-veterans-and-non-veterans-disorder-rates-socio-demographics-co-morbidities-and-quality-of-life
#10
Taeho Greg Rhee, Robert A Rosenheck
BACKGROUND AND OBJECTIVES: Amidst a surging national crisis of opioid use, concern has been expressed about its impact on veterans, but no study has presented a population-based comparison of opioid use disorder (OUD) among veterans and non-veterans. We analyzed national epidemiologic data to compare rates, correlates and impacts of the opioid crisis on male veterans and non-veterans. METHODS: Restricted data from 2012 to 2013 National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III) were used to compare veteran and non-veteran men on rates of OUD, as well as correlates of OUD including socio-demographic characteristics, psychiatric and substance use co-morbidities, and reductions in health-related quality of life (HRQOL)...
January 21, 2019: American Journal on Addictions
https://read.qxmd.com/read/30623502/the-association-of-tobacco-use-with-prescription-of-muscle-relaxants-benzodiazepines-and-opioid-analgesics-for-non-cancer-pain
#11
Hiroko Takaki, Ichiro Ieiri, Hidetoshi Shibuta, Daisuke Onozuka, Akihito Hagihara
BACKGROUND AND OBJECTIVES: Tobacco use and co-prescription of sedative hypnotics are risk factors for misuse of prescribed opioids among patients with non-cancer pain. However, the association between tobacco use and these co-prescriptions has not been clarified. We aimed to assess differences in the prescription and co-prescription rates of opioid analgesics with muscle relaxants and/or benzodiazepines between tobacco users and non-users. METHODS: Visit data were obtained from the 2006 to 2009 National Ambulatory Medical Care Survey, an annual cross-sectional survey of visits to office-based physicians in outpatient settings in the United States...
January 9, 2019: American Journal on Addictions
https://read.qxmd.com/read/30829439/erratum-positive-and-negative-affect-in-cocaine-use-disorder-treatment-change-across-time-and-relevance-to-treatment-outcome
#12
Suzanne E Decker, Kelly Serafini, Kristen P Morie, Bo Malin-Mayo, Charla Nich, Kathleen M Carroll
No abstract text is available yet for this article.
February 2019: American Journal on Addictions
https://read.qxmd.com/read/30829438/issue-information-editorial-board
#13
(no author information available yet)
No abstract text is available yet for this article.
February 2019: American Journal on Addictions
https://read.qxmd.com/read/30829437/issue-information-toc
#14
(no author information available yet)
No abstract text is available yet for this article.
February 2019: American Journal on Addictions
https://read.qxmd.com/read/30829436/cannabis-legislation-and-substance-use-disorder-treatment
#15
Maria K D Schwartz, Hilary Connery
No abstract text is available yet for this article.
February 2019: American Journal on Addictions
https://read.qxmd.com/read/30701620/prescription-opioid-misuse-and-comorbid-substance-use-past-30-day-prevalence-correlates-and-co-occurring-behavioral-indicators-in-the-2016-national-survey-on-drug-use-and-health
#16
Timothy J Grigsby, Jeffrey T Howard
BACKGROUND AND OBJECTIVES: Prescription opioid misuse has not been well examined in the context of comorbid substance use in representative samples of substance users. Past 30-day comorbid prescription opioid misuse and recreational substance use (eg, alcohol, marijuana, cocaine, etc.) was studied in a representative sample of substance users in the United States using the 2016 National Survey on Drug Use and Health (NSDUH). METHODS: Prevalence of prescription opioid misuse with and without comorbid substance use was estimated with the 2016 NSDUH...
February 2019: American Journal on Addictions
https://read.qxmd.com/read/30578727/issue-information-toc
#17
(no author information available yet)
No abstract text is available yet for this article.
January 2019: American Journal on Addictions
https://read.qxmd.com/read/30578726/issue-information-editorial-board
#18
(no author information available yet)
No abstract text is available yet for this article.
January 2019: American Journal on Addictions
https://read.qxmd.com/read/30576034/substance-use-disorder-and-posttraumatic-stress-disorder-symptomology-on-behavioral-outcomes-among-juvenile-justice-youth
#19
Rahissa D Winningham, Devin E Banks, Marcy R Buetlich, Matthew C Aalsma, Tamika C B Zapolski
BACKGROUND AND OBJECTIVES: Substance use behaviors have been identified as a risk factor that places juveniles at greater risk for engaging in delinquent behaviors and continual contact with the juvenile justice system. Currently, there is lack of research that explores comorbid factors associated with substance use, such as post-traumatic stress disorder (PTSD) symptoms, that could help identify youth who are at greatest risk. The aim of the present study was to examine if PTSD symptomology moderated the relationship between substance use disorder (SUD) symptoms and externalizing behaviors and commission of a violent crime; hypothesizing that risk would be heightened among youth with elevated SUD and PTSD symptomology compared to those with elevated SUD symptoms but lower PTSD symptoms...
January 2019: American Journal on Addictions
https://read.qxmd.com/read/30548526/expectations-about-alcohol-cocaine-and-benzodiazepine-abstinence-following-inpatient-heroin-withdrawal-management
#20
Shannon R Kenney, Bradley J Anderson, Genie L Bailey, Michael D Stein
BACKGROUND AND OBJECTIVES: Polysubstance use is associated with relapse and poor treatment outcomes among people dependent on heroin. Despite the high prevalence of polysubstance use among patients detoxifying from heroin, little is known about patients' expectations to abstain or use non-opiate substances. The current study examined factors associated with expectations about abstaining from alcohol, cocaine, and benzodiazepines (BZDs) following heroin withdrawal management. METHODS: Between May and December of 2015, we surveyed 417 patients (71...
December 12, 2018: American Journal on Addictions
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