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Journals ASAIO Journal : a Peer-reviewe...

ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs

https://read.qxmd.com/read/38604137/management-of-left-ventricular-intramural-hematoma-an-unusual-complication-of-complete-atrioventricular-septal-defect-repair-in-a-child
#1
JOURNAL ARTICLE
Sandeep Karanam, Justin Wang, Barnabe Rocha, Thomas Semple, Sylvia Krupickova, Ajay Desai
Postoperative survival for complete atrioventricular septal defect (cAVSD) is excellent. Common complications of surgery include valvular stenosis/regurgitation, left ventricular outflow tract obstruction, arrythmias, and residual defects. We report a challenging case of a 7-month old girl with Trisomy 21, preoperative obstructive sleep apnea with severe pulmonary hypertension, who underwent AVSD repair and required veno-arterial extracorporeal membrane oxygenation (V-A ECMO) while unable to come off cardiopulmonary bypass and developed left ventricular intramural hematoma during the course...
April 12, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38595112/donor-age-more-than-20-years-greater-than-recipient-age-is-associated-with-worse-5-year-survival-in-young-adult-heart-transplantation
#2
JOURNAL ARTICLE
Bryan Lo, Taylor Nordan, Aaron Sparks, Lawrence Lee, Yong Zhan, Frederick Y Chen, Gregory S Couper, Masashi Kawabori
Prior studies indicate donor age-recipient age (DA-RA) difference may be of prognostic value in adolescents, although not adults. We aim to analyze the relationship between DA-RA difference and long-term survival of young adult heart transplantation (HTx) recipients. First-time, single-organ HTx recipients aged 18-30 who underwent HTx between 2010 and 2020 were analyzed from the United Network for Organ Sharing (UNOS) registry. Four cohorts were created based on DA-RA difference. The primary outcome was 5 year post-HTx survival...
April 9, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38595102/influence-of-the-outflow-graft-angular-position-on-the-outcomes-in-patients-with-a-left-ventricular-assist-device
#3
JOURNAL ARTICLE
Casper F Zijderhand, Jette J Peek, Jelena Sjatskig, Olivier C Manintveld, Jos A Bekkers, Ad J J C Bogers, Kadir Caliskan
This study aimed to explore the potential impact of the angular position of the outflow graft on thromboembolic events and aortic valve regurgitation in people with a left ventricular assist device (LVAD). We analyzed contrast computed tomography (CT) data of patients with LVAD implantation between 2016 and 2021. Three-dimensional reconstructions of the outflow graft and aortic arch were performed to calculate the horizontal (azimuth) angle and vertical (polar) angle, as well as the relative distance between the outflow graft, aortic valve, and brachiocephalic artery...
April 9, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38595096/is-infection-prevention-or-adhesion-prevention-the-ultimate-choice
#4
JOURNAL ARTICLE
Yukiharu Sugimura, Tomoyuki Suzuki, Arash Mehdiani, Payam Akhyari, Payam Akhyari
No abstract text is available yet for this article.
April 9, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38595100/an-unexpected-partnership-alexis-carrel-charles-lindbergh-and-normothermic-machine-perfusion
#5
JOURNAL ARTICLE
Ervin Y Cui, Doug A Gouchoe, Suhavi T Salmon-Rekhi, Bryan A Whitson, Sylvester M Black
Organ transplantation is a triumph of modern medicine which represents a culmination of science and imagination, saving thousands of lives a year. However, transplantation is severely limited by suitable donor allografts. To expand the donor pool and make transplantation achievable for all, normothermic machine perfusion (NMP) is being employed more frequently. Normothermic machine perfusion involves the utilization of a device to approximate the physiology of the human body, preserve organs outside of the donor, and provide a dynamic assessment platform to determine organ suitability for transplantation...
April 8, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38588597/steady-flow-left-ventricle-unloading-is-superior-to-pulsatile-pressure-augmentation-venting-during-venoarterial-extracorporeal-membrane-oxygenation-support
#6
JOURNAL ARTICLE
Efrat M Goffer, Kimberly K Lamberti, Anna-Maria Spognardi, Elazer R Edelman, Steven P Keller
Venoarterial extracorporeal membrane oxygenation (VA-ECMO) shunts venous blood to the systemic arterial circulation to provide end-organ perfusion while increasing afterload that may impede left ventricle (LV) ejection and impair cardiac recovery. To maintain flow across the aortic valve and reduce risk of lethal clot formation, secondary mechanical circulatory support (MCS) devices are increasingly used despite limited understanding of their effects on cardiac function. This study sought to quantify the effects of VA-ECMO and combined with either intraaortic balloon pump (IABP) or percutaneous ventricular assist device (pVAD) on LV physiologic state and perfusion metrics in a porcine model of acute cardiogenic shock...
April 8, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38588589/sex-related-differences-in-utilization-and-outcomes-of-extracorporeal-cardio-pulmonary-resuscitation-for-refractory-cardiac-arrest
#7
JOURNAL ARTICLE
Clotilde Balucani, Joseph K Canner, Joseph E Tonna, Heidi Dalton, Riccardo Bianchi, Mais N G Al-Kawaz, Chun Woo Choi, Eric Etchill, Bo Soo Kim, Glenn J Whitman, Sung-Min Cho
Sparse data exist on sex-related differences in extracorporeal cardiopulmonary resuscitation (ECPR) for refractory cardiac arrest (rCA). We explored the role of sex on the utilization and outcomes of ECPR for rCA by retrospective analysis of the Extracorporeal Life Support Organization (ELSO) International Registry. The primary outcome was in-hospital mortality. Exploratory outcomes were discharge disposition and occurrence of any specific extracorporeal membrane oxygenation (ECMO) complications. From 1992 to 2020, a total of 7,460 adults with ECPR were identified: 30...
April 8, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38587868/innovative-percutaneous-3-stitch-suture-technique-for-site-closure-in-venoarterial-extracorporeal-membrane-oxygenation-decannulation-without-direct-artery-repair-a-case-series
#8
JOURNAL ARTICLE
Kaiyi Peng, Linhui Hu, Xiangwei Huang, Yuemei He, Xinxin Wu, Huihua Li, Wentao Zhang, Hengling Zhu, Zheng Wang, Chunbo Chen
No previous studies have reported the use of a percutaneous suture technique performed by bedside intensivists for site closure during decannulation without direct artery repair in venoarterial extracorporeal membrane oxygenation (VA-ECMO) cases. Thus, the objective of this study was to evaluate the safety and effectiveness of this alternative approach. This retrospective study included 26 consecutive patients who underwent percutaneous VA-ECMO decannulation at Maoming People's Hospital. Bedside percutaneous suture technique performed by intensivists facilitated cannula site closure...
April 5, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38574389/damage-associated-molecular-patterns-as-mediators-of-thrombus-formation-on-dialyzer-membrane-in-critically-ill-patients
#9
JOURNAL ARTICLE
Kaori Okamoto, Takashi Ito, Sara Sato, Masahiro Yamamoto, Masaki Takahashi, Yuki Takahashi, Takumi Tsuchida, Asumi Mizugaki, Mineji Hayakawa
This prospective study investigated the relationship between inflammation, damage-associated molecular patterns (DAMPs), and thrombus formation on dialyzer membranes in critically ill patients undergoing renal replacement therapy (RRT) from July 2020 to August 2022, identifying mechanisms and interventions to prevent clotting. The patients were divided into two groups: inflammatory (n = 56, serum C-reactive protein >10 mg/dl) and noninflammatory control (n = 45, serum C-reactive protein <5 mg/dl)...
April 5, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38569187/the-impact-of-rotor-axial-displacement-variation-on-simulation-accuracy-of-fully-magnetic-levitation-centrifugal-blood-pump
#10
JOURNAL ARTICLE
Yuan Li, Yifeng Xi, Hongyu Wang, Anqiang Sun, Xiaoyan Deng, Zengsheng Chen, Yubo Fan
The rotor axial displacement of the full magnetic levitation blood pump varies with the operating conditions. The effect of rotor axial displacement on simulation results is unclear. This study aimed to evaluate the effect of rotor axial displacement on the predicted blood pump flow field, hydraulic performance, and hemocompatibility through simulation. This study used the CentriMag blood pump as a model, and conducted computational fluid dynamics simulations to assess the impact of rotor displacement. Considering rotor axial displacement leads to opposite results regarding predicted residence time and thrombotic risk compared with not considering rotor axial displacement...
April 4, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38569184/hemodynamical-evaluation-of-a-new-surgically-implanted-pulsatile-right-ventricular-assist-device-driven-by-a-conventional-intra-aortic-balloon-pump-console
#11
JOURNAL ARTICLE
Sara Knigge, Günes Dogan, Ezin Deniz, Youseph Ismail, Jörg Optenhöfel, Liam Schana, Ali S Merzah, Jasmin S Hanke, Issam Ismail, Oren Malchin, Marcelo Bastos, Aron F Popov, Alexander Weymann, Arjang Ruhparwar, Bastian Schmack, Jan D Schmitto
Severe right heart failure, often overlooked and challenging to manage, has prompted a growing interest in innovative approaches to provide functional support. This study uses experimentation in large porcine models to introduce a novel prototype of a pulsatile mechanical circulatory support device and document its effects when deployed as a right ventricular assist device (RVAD). The pulsatile ventricular assist platform (pVAP), featuring a membrane pump driven by an intra-aortic balloon pump console, actively generates pulsatile flow to propel right ventricular blood into the pulmonary artery...
April 4, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38552179/volume-displacement-pulsatile-veno-arterial-extracorporeal-membrane-oxygenation-preliminary-data-from-in-vitro-tests
#12
JOURNAL ARTICLE
Silver Heinsar, Clayton Semenzin, Samia M Farah, John F Fraser
No abstract text is available yet for this article.
March 30, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38557701/anatomical-and-hemodynamic-characterization-of-totally-artificial-hearts
#13
JOURNAL ARTICLE
Gretel Monreal, Steven C Koenig, Jiapeng Huang, Mark S Slaughter
We characterize the anatomy and function of never before studied total artificial hearts (TAHs) using established methods for testing mechanical circulatory support (MCS) devices. A historical review of TAHs is also presented to aid in benchmarking performance metrics. Six TAHs, ranging from spooky Halloween beating hearts to a cute colorful plush heart, were imaged, instrumented (mock flow loops) to measure their pressure, volume, and flow, and qualitatively evaluated by 3rd party cardiac surgeons for anatomical accuracy and surgical considerations...
March 28, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38552178/deceased-donor-kidney-transplant-outcome-prediction-using-artificial-intelligence-to-aid-decision-making-in-kidney-allocation
#14
JOURNAL ARTICLE
Hatem Ali, Mahmoud Mohamed, Miklos Z Molnar, Tibor Fülöp, Bernard Burke, Arun Shroff, Sunil Shroff, David Briggs, Nithya Krishnan
In kidney transplantation, pairing recipients with the highest longevity with low-risk allografts to optimize graft-donor survival is a complex challenge. Current risk prediction models exhibit limited discriminative and calibration capabilities and have not been compared to modern decision-assisting tools. We aimed to develop a highly accurate risk-stratification index using artificial intelligence (AI) techniques. Using data from the UNOS database (156,749 deceased kidney transplants, 2007-2021), we randomly divided transplants into training (80%) and validation (20%) sets...
March 28, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38537074/development-of-the-psu-child-pump
#15
JOURNAL ARTICLE
Christopher Scheib, Raymond Newswanger, Joshua Cysyk, Karl Bohnenberger, Branka Lukic, Lichong Xu, Eric Yeager, Kirby Bletcher, Patrick Leibich, Quandashia Jackson, Heidi Flory, Mindy Tillinger, William Weiss, Gerson Rosenberg, Choon-Sik Jhun
The Pennsylvania State University (PSU) Child Pump, a centrifugal continuous-flow ventricular assist device (cf-VAD), is being developed as a suitable long-term implantable device for pediatric heart failure patients between 10 and 35 kg, body surface area (BSA) of 0.5-1.2 m2, 1-11 years of age, and requiring a mean cardiac output of 1.0-3.5 L/min. In-vitro hydraulic and hemodynamic performances were evaluated on a custom mock circulatory loop with ovine blood. Normalized index of hemolysis (NIH) was evaluated under four conditions: 1) 8,300 rpm, 3...
March 28, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38537063/impella-as-bridge-to-durable-left-ventricular-assist-device-in-acute-myocardial-infarction-cardiogenic-shock-patients
#16
JOURNAL ARTICLE
Silvia Ajello, Marina Pieri, Sara Dormio, Luca Baldetti, Savino Altizio, Filippo Consolo, Pasquale Nardelli, Alessandro Ortalda, Anna Mara Scandroglio
Implantation of durable left ventricular assist device (LVAD) in cardiogenic shock (CS) patients after acute myocardial infarction (AMI) poses specific challenges (small left ventricular size, acute infarct area, need for antithrombotic therapy, status Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) 1 with impaired organ function and derangements in coagulation and inflammatory parameters) which may affect outcomes. We reviewed data of all AMI-CS patients who were implanted LVAD after Impella support at a referral center with the aim to analyze feasibility, timing, and outcomes of durable LVAD implantation after tMCS with Impella due to AMI-CS...
March 28, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38551498/interaction-of-a-ventricular-assist-device-with-patient-specific-cardiovascular-systems-in-silico-study-with-bidirectional-coupling
#17
JOURNAL ARTICLE
Mario Hahne, Vincenz Crone, Inga Thomas, Calvin Wolfgramm, Frieder Kurt Peter Liedtke, Frank-Hendrik Wurm, Benjamin Torner
Ventricular assist devices (VADs) are used to assist the heart function of patients with advanced heart failure. Computational fluid dynamics in VADs are widely applied in the development and optimization, for example, to evaluate blood damage. For these simulations, the pulsating operating conditions, in which the VAD operates, should be included accurately. Therefore, this study aims to evaluate the flow in a VAD by interacting with patient-specific cardiovascular systems of heart failure patients. A numeric method will be presented, which includes a patient-specific cardiovascular system model that is bidirectionally coupled with a three-dimensional (3D) flow simulation of the HeartMate 3...
March 27, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38531093/intraoperative-use-of-intra-aortic-balloon-pump-to-generate-pulsatile-flow-during-heart-transplantation-a-single-center-experience
#18
JOURNAL ARTICLE
Les James, Michael P Dorsey, Sumner E Kilmarx, Sallie Yassin, Shashwat Shrivastava, Neil Menghani, Vikram Bajaj, Eugene A Grossi, Aubrey C Galloway, Nader Moazami, Deane E Smith
The physiologic impact of pulsatile flow (PF) on end-organ perfusion during cardiopulmonary bypass (CPB) is controversial. Using an intra-aortic balloon pump (IABP) to maintain PF during CPB for patients undergoing heart transplantation (HT) may impact end-organ perfusion, with implications for postoperative outcomes. A single-center retrospective study of 76 patients bridged to HT with IABP was conducted between January 2018 and December 2022. Beginning in May 2022, patients received IABP-generated PF during CPB at an internal rate of 80 beats/minute...
March 27, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38527077/body-mass-index-and-mortality-in-cardiogenic-shock
#19
JOURNAL ARTICLE
Maya Guglin, Elric Zweck, Manreet Kanwar, Shashank S Sinha, Arvind Bhimaraj, Borui Li, Jacob Abraham, Saraschandra Vallabhajosyula, Jaime Hernandez-Montfort, Rachna Kataria, Daniel Burkhoff, Navin K Kapur
We explored the association of body mass index (BMI) with mortality in cardiogenic shock (CS). Using the Cardiogenic Shock Working Group registry, we assessed the impact of BMI on mortality using restricted cubic splines in a multivariable logistic regression model adjusting for age, gender, and race. We also assessed mortality, device use, and complications in BMI categories, defined as underweight (<18.5 kg/m2), normal (18.5-24.9 kg/m2), overweight (25-29.9 kg/m2), obese (30-39.9 kg/m2), and severely obese (>40 kg/m2) using univariable logistic regression models...
March 25, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://read.qxmd.com/read/38513112/comparison-of-mixed-venous-oxygen-saturation-and-premembranous-venous-oxygen-saturation-in-patients-on-peripheral-venous-arterial-extracorporeal-membrane-oxygenation
#20
JOURNAL ARTICLE
Kevin J John, Dinesh J Belani, Navin K Kapur, Leslie Lussier, Haval Chweich
In patients on veno-arterial extracorporeal membrane oxygenation (ECMO) premembranous venous oxygen saturation (Spm-vO2) is continuously displayed on the ECMO console. However, the concordance between Spm-vO2 and mixed venous oxygen saturation (SvO2) remains largely unexplored. Our single-center retrospective study included adult patients who had paired SvO2 and Spm-vO2 readings within 15 minutes of each other, on peripherally cannulated Vf ivc-A ECMO and a pulmonary artery using catheter (PAC). The 82 pairs of observations showed a mean difference of 11...
March 22, 2024: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
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