journal
https://read.qxmd.com/read/38445376/prevention-diagnosis-and-treatment-of-urolithiasis-in-geriatric-patients-differences-similarities-and-caveats-in-comparison-to-the-general-population
#1
JOURNAL ARTICLE
Tarek A Schrag, Danielle Diarra, Julian Veser
PURPOSE OF THE REVIEW: Purpose of the review is to address management and prevention of urolithiasis in elderly patients examining the dynamic interplay between general measures, dietary adjustments, lifestyle modifications, and targeted pharmacological and/ or surgical interventions. The goal is to provide understanding of the evolving strategies required for effective urolithiasis prevention in the geriatric population. RECENT FINDINGS: Age-specific diagnostic considerations are necessary because urolithiasis in the elderly population is characterized by bigger stones, greater peri-operative risks, and heightened symptom severity...
March 6, 2024: Current Opinion in Urology
https://read.qxmd.com/read/38445371/optimal-systemic-therapy-in-men-with-low-volume-prostate-cancer
#2
JOURNAL ARTICLE
Akshat Saxena, Jack Andrews, Alan Haruo Bryce, Irbaz Bin Riaz
PURPOSE OF REVIEW: Low-volume prostate cancer is an established prognostic category of metastatic hormone-sensitive prostate cancer. However, the term is often loosely used to reflect the low burden of disease across different prostate cancer states. This review explores the definitions of low-volume prostate cancer, biology, and current evidence for treatment. We also explore future directions, including the impact of advanced imaging modalities, particularly prostate-specific membrane antigen (PSMA) positron emission tomography (PET) scans, on refining patient subgroups and treatment strategies for patients with low-volume prostate cancer...
March 6, 2024: Current Opinion in Urology
https://read.qxmd.com/read/38440850/preoperative-geriatric-assessment-of-urological-patients-a-narrative-review
#3
JOURNAL ARTICLE
Marcus Köller
PURPOSE OF REVIEW: The proportion of older people is increasing disproportionately. The age between 60 and 65 years is seen as the transition to 'old age'. Frailty is a risk factor for morbidity, mortality, and complications in the context of medical interventions or adverse effects of drug therapies. One of the core components of frailty, the age-related loss of muscle mass, is sarcopenia. Is there an influence of frailty, as well as sarcopenia and some other aspects, i.e. malnutrition, on the outcome in elderly urologic patients? RECENT FINDINGS: These phenomena of aging correlate with the incidence postoperative complication, infections, readmission rates or mortality...
March 5, 2024: Current Opinion in Urology
https://read.qxmd.com/read/38426242/definitions-outcomes-and-perspectives-for-oligometastatic-bladder-cancer-towards-a-standardized-terminology
#4
JOURNAL ARTICLE
Giorgio Calleris, Markus von Deimling, Claudia Kesch, Francesco Soria, Paolo Gontero, Guillaume Ploussard, Ekaterina Laukhtina, Benjamin Pradère
PURPOSE OF REVIEW: Oligometastatic (om) cancer is considered as a transitional state in between locally confined disease and widespread metastases, accessible to a multimodal treatment, combining systemic and local therapy. In urothelial bladder cancer (BCa), the definitions and the approaches to this condition are poorly standardised and mainly based on retrospective data. We aim to portray the framework for uro-oncologic terminology in omBCa and go through the latest evidence and the future perspectives...
March 1, 2024: Current Opinion in Urology
https://read.qxmd.com/read/38426237/effect-of-increasing-age-and-ureteral-stent-implantation-on-urinary-tract-infections-after-kidney-transplantation-update-of-recent-literature
#5
JOURNAL ARTICLE
Haris Omic, Michael Eder
PURPOSE OF REVIEW: This review aims to present the recent literature regarding effects of aging and ureteral stent implantation (UrS) on the risk of urinary tract infections (UTIs) in kidney transplant (KTX) recipients. RECENT FINDINGS: UTIs in kidney transplant recipients remain a clinical challenge and represent a leading cause of morbidity, hospitalization rates, and mortality. Higher age was described as a significant risk factor for UTIs in several studies including a recent Brazilian analysis, indicating a 3...
March 1, 2024: Current Opinion in Urology
https://read.qxmd.com/read/38426229/metastasis-directed-therapy-in-oligometastatic-prostate-cancer
#6
JOURNAL ARTICLE
Marcin Miszczyk, Timo Soeterik, Giancarlo Marra, Akihiro Matsukawa, Shahrokh F Shariat
PURPOSE OF REVIEW: To summarize the recent findings on the subject of metastasis-directed therapy (MDT) in the treatment of oligometastatic prostate cancer (omPCa). RECENT FINDINGS: Evidence from two randomized clinical trials (RCTs) and a meta-analysis show favorable toxicity profiles, and the potential to delay androgen-deprivation therapy (ADT) for up to two years in nearly half of patients with metachronous hormone-sensitive omPCa. Another RCT showed promising results of MDT as treatment-escalation method combined with androgen receptor signaling inhibitors (ARSI) in first-line treatment for castration-resistant omPCa...
March 1, 2024: Current Opinion in Urology
https://read.qxmd.com/read/38410848/the-histomorphology-of-the-senescent-kidney-the-clinical-relevance-of-specimen-and-biopsy-findings-in-the-elderly-native-kidneys
#7
JOURNAL ARTICLE
Nicolas Kozakowski
PURPOSE OF THE REVIEW: Renal pathology is crucial in diagnosing the ageing kidney. Recent technological advances enabled high-resolution molecular investigations into the complex mechanisms of ageing and senescence. RECENT FINDINGS: The pathological analysis of large kidney tissue collections coupled with computer-assisted morphometry contributed to the establishment of age-related reference values for glomerular or vascular sclerosis, interstitial fibrosis, and tubular atrophy...
February 27, 2024: Current Opinion in Urology
https://read.qxmd.com/read/38305430/testicular-cancer-with-small-metastatic-burden-optimal-approach-in-2024
#8
JOURNAL ARTICLE
Kit L Yuen, Kshitij Pandit, Dhruv Puri, Nuphat Yodkhunnatham, Aditya Bagrodia
PURPOSE OF REVIEW: Recent advancements in the management of clinical stage II (CS II) testicular cancer have transformed it into a predominantly curable condition. This success in treatment advancements has markedly extended patient survival. However, these treatments carry risks and morbidities, which is important to consider given the disease's impact on young men and the emerging understanding of long-term treatment consequences. RECENT FINDINGS: Emerging data support primary retroperitoneal lymph node dissection (RPLND) for select CS II seminoma patients, with similar short-term outcomes to chemotherapy but less treatment intensity...
February 3, 2024: Current Opinion in Urology
https://read.qxmd.com/read/38305293/current-evidence-on-local-therapy-in-oligometastatic-prostate-cancer
#9
JOURNAL ARTICLE
Spyridon P Basourakos, Grant Henning, R Jeffrey Karnes
PURPOSE OF REVIEW: Metastatic prostate cancer (PCa) continues to be an invariably fatal condition. While historically, de-novo metastatic PCa was primarily treated with androgen deprivation therapy (ADT) and systemic therapy, there is a growing trend toward incorporating local treatments in the early management of the disease. This is particularly applicable to men with oligometastatic PCa (OMPC), which represents an 'intermediate phase' between localized and disseminated metastatic disease...
February 2, 2024: Current Opinion in Urology
https://read.qxmd.com/read/38240477/beyond-the-knife-strategic-patient-selection-for-cytoreductive-nephrectomy
#10
JOURNAL ARTICLE
Stephan Brönimann, Yasser Ged, Nirmish Singla
PURPOSE OF REVIEW: To evaluate the current role of cytoreductive nephrectomy (CN) in metastatic renal cell carcinoma (mRCC) within the context of evolving treatment paradigms, focusing on implications for patient selection. RECENT FINDINGS: Two randomized trials failed to show significant benefits from CN for intermediate and poor-risk patients undergoing targeted therapy. Despite this, subgroup analysis and retrospective data suggest potential benefits for a subset of good and intermediate-risk patients...
January 19, 2024: Current Opinion in Urology
https://read.qxmd.com/read/38321978/endo-technology-and-its-future-where-are-we-heading
#11
JOURNAL ARTICLE
Bhaskar K Somani, Jens Rassweiler
No abstract text is available yet for this article.
March 1, 2024: Current Opinion in Urology
https://read.qxmd.com/read/38321977/pelvic-pain-syndromes
#12
JOURNAL ARTICLE
John Heesakkers, Dick Janssen
No abstract text is available yet for this article.
March 1, 2024: Current Opinion in Urology
https://read.qxmd.com/read/38168016/what-is-in-the-pipeline-for-new-treatments-for-bladder-pain-syndrome-interstitial-cystitis
#13
REVIEW
Diogo Dias, Pedro Abreu Mendes, Paulo Dinis Oliveira, Rui Almeida Pinto
PURPOSE OF REVIEW: Despite available treatments, many bladder pain syndrome/interstitial cystitis (BPS/IC) patients continue to have poor quality of life. Thus, there is an urge for new therapies. Our manuscript aims to review papers about BPS/IC treatments published in the last 2 years. RECENT FINDINGS: During this period, several treatments were tested, most of them new and others combining treatments already used. Pentosan polysulfate, interleukin 1 antagonist, low energy shock wave, physical therapy, hypnosis, acupuncture, clorpactin, dimethyl sulfoxide and hyaluronic acid plus botulinum toxin-A showed positive results...
March 1, 2024: Current Opinion in Urology
https://read.qxmd.com/read/37962176/chatgpt-in-urology-practice-revolutionizing-efficiency-and-patient-care-with-generative-artificial-intelligence
#14
REVIEW
Carlotta Nedbal, Nitesh Naik, Daniele Castellani, Vineet Gauhar, Robert Geraghty, Bhaskar Kumar Somani
PURPOSE OF REVIEW: ChatGPT has emerged as a potentially useful tool for healthcare. Its role in urology is in its infancy and has much potential for research, clinical practice and for patient assistance. With this narrative review, we want to draw a picture of what is known about ChatGPT's integration in urology, alongside future promises and challenges. RECENT FINDINGS: The use of ChatGPT can ease the administrative work, helping urologists with note-taking and clinical documentation such as discharge summaries and clinical notes...
March 1, 2024: Current Opinion in Urology
https://read.qxmd.com/read/38054212/editorial-introductions
#15
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
January 1, 2024: Current Opinion in Urology
https://read.qxmd.com/read/37909886/simulation-training-in-urology
#16
REVIEW
J Everett Knudsen, Runzhuo Ma, Andrew J Hung
PURPOSE OF REVIEW: This review outlines recent innovations in simulation technology as it applies to urology. It is essential for the next generation of urologists to attain a solid foundation of technical and nontechnical skills, and simulation technology provides a variety of safe, controlled environments to acquire this baseline knowledge. RECENT FINDINGS: With a focus on urology, this review first outlines the evidence to support surgical simulation, then discusses the strides being made in the development of 3D-printed models for surgical skill training and preoperative planning, virtual reality models for different urologic procedures, surgical skill assessment for simulation, and integration of simulation into urology residency curricula...
January 1, 2024: Current Opinion in Urology
https://read.qxmd.com/read/38117118/latest-insights-into-the-pathophysiology-of-bladder-pain-syndrome-interstitial-cystitis
#17
JOURNAL ARTICLE
Jure Tornic, Daniel Engeler
PURPOSE OF REVIEW: Bladder pain syndrome/interstitial cystitis (BPS/IC) is a common medical problem in both sexes affecting people of all ages. Patients might report overactive bladder symptoms with additional bladder pain at maximum bladder filling, during and after micturition. This review aims to highlight pathophysiological mechanisms associated with this disease. RECENT FINDINGS: Latest literature exposes different pathophysiological mechanisms such as impaired urothelial barrier function, alteration of urothelial factors and cytokines, chronic inflammation, vascular lesions, neurogenic inflammation and processes in the central nervous system leading to central sensitization...
December 21, 2023: Current Opinion in Urology
https://read.qxmd.com/read/38038411/digital-health-innovations-in-urology-telemedicine-wearables-and-mobile-applications-a-systematic-review-of-literature
#18
JOURNAL ARTICLE
Nithesh Naik, Ali Talyshinskii, Jens Rassweiler, B M Zeeshan Hameed, Bhaskar K Somani
PURPOSE OF REVIEW: There are enough publications on the use of telemedicine, wearable devices, and mobile applications in urology; however, their collective impact on urological care has not been adequately studied. This review seeks to address this deficiency by providing a descriptive analysis of the recent use of telemedicine, wearable technology, and mobile applications in urology as well as elucidating their associated challenges. RECENT FINDINGS: There are studies that were dedicated to the use of telemedicine, wearables, and mobile apps in urology according to inclusion criteria, respectively...
December 4, 2023: Current Opinion in Urology
https://read.qxmd.com/read/37975427/bladder-pain-syndrome-aka-interstitial-cystitis-a-condition-with-severe-unmet-medical-need-an-exploration-of-brimapitide-as-a-potential-treatment-opportunity
#19
JOURNAL ARTICLE
Erich Taubert, Frank van de Aa, John Heesakkers
PURPOSE OF REVIEW: The purpose of this article is to present recent findings of KU002 (brimapitide) as a novel treatment option for interstitial cystitis/bladder pain syndrome (IC/BPS). RECENT FINDINGS: IC/BPS is a complex and poorly understood heterogeneous syndrome, with many burdensome symptoms that severely affect patients' quality of life. Treatment options beyond conservative and nonpharmacologic approaches remain limited, and there is an unmet medical need for effective medical treatments...
November 20, 2023: Current Opinion in Urology
https://read.qxmd.com/read/37962372/single-use-flexible-ureteroscopes-a-review-of-current-technologies-and-cost-effectiveness-analysis
#20
JOURNAL ARTICLE
Ali Talyshinskii, Vineet Gauhar, Daniele Castellani, Thomas Knoll, Kaushikkumar Shah, Shaw P Wan, Bhaskar K Somani
PURPOSE OF REVIEW: Flexible ureteroscopy (fURS) has evolved into both diagnostic and therapeutic modalities. Our review discusses the cost-effectiveness of single use flexible ureteroscopes (su-fURS) and the use of these instruments in routine urological practice. RECENT FINDINGS: There are studies which support the use of su-fURS with an argument of both cost and clinical utility over reusable flexible ureteroscopes (ru-fURS). However, the cost may vary across countries, hence is difficult to compare the results based on the current literature...
November 15, 2023: Current Opinion in Urology
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