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Journals Cellular Physiology and Bioche...

Cellular Physiology and Biochemistry

https://read.qxmd.com/read/39012386/is-salivary-%C3%AE-amylase-a-reliable-indicator-of-psychological-status-and-quality-of-life-in-patients-with-oral-lichen-planus-a-case-control-study
#1
JOURNAL ARTICLE
Ana Glavina, Antonija Zoranić, Antonija Tadin, Livia Cigić, Daniela Šupe-Domić, Liborija Lugović-Mihić
BACKGROUND/AIMS: The objectives of our study were to determine salivary α-amylase activity (stress biomarker) and its association with psychological status and quality of life (QoL), disease duration and intensity of symptoms (pain/burning) in patients with OLP. METHODS: A total of 50 subjects participated in this case-control study: 30 patients with oral lichen planus (OLP); 20 control subjects. Unstimulated whole saliva (UWS) was collected between 9 and 10 am to avoid diurnal fluctuations...
July 12, 2024: Cellular Physiology and Biochemistry
https://read.qxmd.com/read/38973197/role-of-piezo2-in-schwann-cell-volume-regulation-and-its-impact-on-neurotrophic-release-regulation
#2
JOURNAL ARTICLE
Chawapun Suttinont, Katsuyuki Maeno, Mamiko Yano, Kaori Sato-Numata, Tomohiro Numata, Moe Tsutsumi
BACKGROUND/AIMS: Tactile perception relies on mechanoreceptors and nerve fibers, including c-fibers, Aβ-fibers and Aδ-fibers. Schwann cells (SCs) play a crucial role in supporting nerve fibers, with non-myelinating SCs enwrapping c-fibers and myelinating SCs ensheathing Aβ and Aδ fibers. Recent research has unveiled new functions for cutaneous sensory SCs, highlighting the involvement of nociceptive SCs in pain perception and Meissner corpuscle SCs in tactile sensation...
July 8, 2024: Cellular Physiology and Biochemistry
https://read.qxmd.com/read/38958399/retraction
#3
(no author information available yet)
No abstract text is available yet for this article.
June 30, 2024: Cellular Physiology and Biochemistry
https://read.qxmd.com/read/38958398/retraction
#4
(no author information available yet)
No abstract text is available yet for this article.
June 30, 2024: Cellular Physiology and Biochemistry
https://read.qxmd.com/read/38958397/expression-of-concern
#5
EDITORIAL
(no author information available yet)
No abstract text is available yet for this article.
June 30, 2024: Cellular Physiology and Biochemistry
https://read.qxmd.com/read/38958396/expression-of-concern
#6
EDITORIAL
(no author information available yet)
No abstract text is available yet for this article.
June 30, 2024: Cellular Physiology and Biochemistry
https://read.qxmd.com/read/38881348/cardiotoxicity-induced-by-intratracheal-instillation-of-diesel-exhaust-particles-in-mice-and-the-protective-effects-of-carnosol-suppression-of-inflammation-and-oxidative-and-nitrosative-stress-via-modulation-of-nf-%C3%AE%C2%BAb-mapks-signaling-pathways
#7
JOURNAL ARTICLE
Nur Elena Zaaba, Sumaya Beegam, Ozaz Elzaki, Mohammad Albastaki, Majed Alhammadi, Abdallah Alsaadi, Abderrahim Nemmar
BACKGROUND/AIMS: Inhaled particulate air pollution is associated with cardiotoxicity with underlying mechanisms including oxidative stress and inflammation. Carnosol, commonly found in rosemary and sage, is known to possess a broad range of therapeutic properties such as antioxidant, anti-inflammatory and antiapoptotic. However, its cardioprotective effects on diesel exhaust particles (DEPs)-induced toxicity have not been studied yet. Hence, we evaluated the potential ameliorative effects of carnosol on DEPs-induced heart toxicity in mice, and the underlying mechanisms involved...
June 14, 2024: Cellular Physiology and Biochemistry
https://read.qxmd.com/read/38865588/curbing-breast-cancer-by-altering-v-atpase-action-on-f-actin-heterochromatin-etv7-and-mtorc2-signaling
#8
JOURNAL ARTICLE
Zeina S Khan, Fazle Hussain
BACKGROUND/AIMS: Motivated by the vacuolar proton pump's importance in cancer, we investigate the effects of proton pump inhibition on breast cancer cell migration and proliferation, F-actin polymerization, lamin A/C, heterochromatin, and ETV7 expressions, nuclear size and shape, and AKT/mTOR signaling. METHODS: Lowly metastatic MCF7 and highly metastatic MDA-MB-231 breast cancer cells were treated with 120 nM of proton pump inhibitor Bafilomycin A1 for 24 hours...
June 12, 2024: Cellular Physiology and Biochemistry
https://read.qxmd.com/read/38857359/adaptive-effects-of-intermittent-hypoxia-training-on-oxygen-dependent-processes-as-a-potential-therapeutic-strategy-tool
#9
JOURNAL ARTICLE
Natalia Kurhaluk, Oleksandr Lukash, Piotr Kamiński, Halina Tkaczenko
BACKGROUND/AIMS: Important benefits of intermittent hypoxic training (IHT) have emerged as an effective tool for enhancing adaptive potential in different pathological states, among which acute hypoxia dominates. Therefore, the aim of our study was to evaluate the mechanisms related to the effects of the nitric oxide system (nitrites, nitrates, carbamide, and total polyamine content) on ADP-stimulated oxygen consumption and oxidative phosphorylation in heart and liver mitochondria and biomarkers of oxidative stress in the blood, heart, and liver of rats exposed to the IHT method and acute hypoxia and treated with the amino acid L-arginine (600 mg/kg, 30 min) or the NO synthase inhibitor L-NNA (35 mg/kg, 30 min) prior to each IHT session...
June 10, 2024: Cellular Physiology and Biochemistry
https://read.qxmd.com/read/38852193/prazosin-potentiates-mast-cell-stabilizing-property-of-adrenaline
#10
JOURNAL ARTICLE
Nozomu Abe, Hiroaki Toyama, Yutaka Ejima, Kazutomo Saito, Tsutomu Tamada, Masanori Yamauchi, Itsuro Kazama
BACKGROUND/AIMS: Adrenaline quickly inhibits the release of histamine from mast cells. Besides β2-adrenergic receptors, several in vitro studies also indicate the involvement of α-adrenergic receptors in the process of exocytosis. Since exocytosis in mast cells can be detected electrophysiologically by the changes in the membrane capacitance (Cm), its continuous monitoring in the presence of drugs would determine their mast cell-stabilizing properties. METHODS: Employing the whole-cell patch-clamp technique in rat peritoneal mast cells, we examined the effects of adrenaline on the degranulation of mast cells and the increase in the Cm during exocytosis...
May 9, 2024: Cellular Physiology and Biochemistry
https://read.qxmd.com/read/38852191/significant-association-of-candidate-genes-agtr1-and-tgf-%C3%AE-1-polymorphism-with-diabetic-nephropathy-in-diabetes-mellitus-type-2-patients
#11
JOURNAL ARTICLE
Madeeha Ihsan, Najeeb Ullah Khan, Noreen Asim, Muhammad Ismail, Mikhlid H Almutairi, Ijaz Ali, Brian D Adams
BACKGROUND/AIMS: Diabetic nephropathy (DN) is one of the complications of diabetes mellitus (DM). This study aimed to investigate the association between genetic polymorphisms, specifically AGTR1 (rs5186) and TGF-β1 (rs1800470), and the risk of developing Diabetic nephropathy (DN) in type 2 diabetes mellitus patients, compared to those without DN and healthy controls. METHODS: A case-control study was conducted on 165 diabetic patients (59 with diabetic nephropathy (DN) and 54 without DN (DM)), and 52 healthy controls (HC)...
May 6, 2024: Cellular Physiology and Biochemistry
https://read.qxmd.com/read/38734962/retraction
#12
(no author information available yet)
No abstract text is available yet for this article.
April 30, 2024: Cellular Physiology and Biochemistry
https://read.qxmd.com/read/38734961/retraction
#13
(no author information available yet)
No abstract text is available yet for this article.
April 30, 2024: Cellular Physiology and Biochemistry
https://read.qxmd.com/read/38734960/retraction
#14
(no author information available yet)
No abstract text is available yet for this article.
April 30, 2024: Cellular Physiology and Biochemistry
https://read.qxmd.com/read/38734959/erratum
#15
(no author information available yet)
No abstract text is available yet for this article.
April 30, 2024: Cellular Physiology and Biochemistry
https://read.qxmd.com/read/38734958/erratum
#16
(no author information available yet)
No abstract text is available yet for this article.
April 30, 2024: Cellular Physiology and Biochemistry
https://read.qxmd.com/read/38734957/erratum
#17
(no author information available yet)
No abstract text is available yet for this article.
April 30, 2024: Cellular Physiology and Biochemistry
https://read.qxmd.com/read/38643508/acid-sensitive-outwardly-rectifying-cl-current-in-ov2944-mouse-ovarian-cancer-cells
#18
JOURNAL ARTICLE
Hajime Hirasawa, Kayo Aoba, Naofumi Miwa
BACKGROUND/AIMS: Extracellular acidic conditions impair cellular activities; however, some cancer cells drive cellular signaling to adapt to the acidic environment. It remains unclear how ovarian cancer cells sense changes in extracellular pH. This study was aimed at characterizing acid-inducible currents in an ovarian cancer cell line and evaluating the involvement of these currents in cell viability. METHODS: The biophysical and pharmacological properties of membrane currents in OV2944, a mouse ovarian cancer cell line, were studied using the whole-cell configuration of the patch-clamp technique...
April 20, 2024: Cellular Physiology and Biochemistry
https://read.qxmd.com/read/38639210/pancreas-%C3%AE-cells-in-type-1-and-type-2-diabetes-cell-death-oxidative-stress-and-immune-regulation-recently-appearing-changes-in-diabetes-consequences
#19
JOURNAL ARTICLE
Elena G Novoselova, Sergey M Lunin, Maxim O Khrenov, Olga V Glushkova, Tatyana V Novoselova, Svetlana B Parfenyuk
Diabetes mellitus type 1 (T1D) and type 2 (T2D) develop due to dysfunction of the Langerhans islet β-cells in the pancreas, and this dysfunction is mediated by oxidative, endoplasmic reticulum (ER), and mitochondrial stresses. Although the two types of diabetes are significantly different, β-cell failure and death play a key role in the pathogenesis of both diseases, resulting in hyperglycemia due to a reduced ability to produce insulin. In T1D, β-cell apoptosis is the main event leading to hyperglycemia, while in T2D, insulin resistance results in an inability to meet insulin requirements...
April 17, 2024: Cellular Physiology and Biochemistry
https://read.qxmd.com/read/38623065/brca2-polymorphisms-and-breast-cancer-susceptibility-a-multi-tools-bioinformatics-approach
#20
JOURNAL ARTICLE
Haris Jan, Najeeb Ullah Khan, Ayman M Al-Qaaneh, Munazzah Tasleem, Mikhlid H Almutairi, Ijaz Ali
BACKGROUND/AIMS: The main focus of this investigation is to identify deleterious single nucleotide polymorphisms (SNPs) located in the BRCA2 gene through in silico approach, thereby,providing an understanding of potential consequences regarding the susceptibility to breast cancer. METHODS: The GenomAD database was used to identify SNPs. To determine the potential adverse consequences, our study employed various prediction tools, including SIFT, PolyPhen, PredictSNP, SNAP2, PhD-SNP, and ClinVar...
March 24, 2024: Cellular Physiology and Biochemistry
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