Boukje C Eveleens Maarse, Hannah M Eggink, Ines Warnke, Sabina Bijlsma, Tim J van den Broek, Johanneke E Oosterman, Martien P M Caspers, Wilbert Sybesma, Pim Gal, Sebastiaan J W van Kraaij, Frank H J Schuren, Matthijs Moerland, Femke P M Hoevenaars
BACKGROUND AND AIMS: The gut microbiome exerts important roles in health, e.g., functions in metabolism and immunology. These functions are often exerted via short-chain fatty acid (SCFA) production by gut bacteria. Studies demonstrating causal relationships between interventions targeting the microbiome and clinical outcomes are limited. This study aimed to show a causal relationship between microbiome modulation through fibre intervention and health. METHODS AND RESULTS: This randomized, double-blind, cross-over study included 65 healthy subjects, aged 45-70 years, with increased metabolic risk (i...
February 6, 2024: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD