Annalisa Boscolo, Tommaso Pettenuzzo, Nicolò Sella, Matteo Zatta, Michele Salvagno, Martina Tassone, Chiara Pretto, Arianna Peralta, Luisa Muraro, Francesco Zarantonello, Andrea Bruni, Federico Geraldini, Alessandro De Cassai, Paolo Navalesi
BACKGROUND: The effect of noninvasive respiratory support (NRS), including high-flow nasal oxygen, bi-level positive airway pressure and continuous positive airway pressure (noninvasive ventilation (NIV)), for preventing and treating post-extubation respiratory failure is still unclear. Our objective was to assess the effects of NRS on post-extubation respiratory failure, defined as re-intubation secondary to post-extubation respiratory failure (primary outcome). Secondary outcomes included the incidence of ventilator-associated pneumonia (VAP), discomfort, intensive care unit (ICU) and hospital mortality, ICU and hospital length of stay (LOS), and time to re-intubation...
June 30, 2023: European Respiratory Review: An Official Journal of the European Respiratory Society