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European Journal of Ophthalmology

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https://read.qxmd.com/read/30757919/the-use-of-bevacizumab-in-pediatric-retinal-and-choroidal-disease-a-review
#1
Peter J Belin, Andrew C Lee, Giovanni Greaves, Jennifer Kosoy, Ronni M Lieberman
The use of intravitreal bevacizumab in pediatric retinal and uveitic disease has become more widespread over the past decade. This article serves to outline the rationale underlying the use of intravitreal bevacizumab, and which disease entities it should be appropriately thought of as a primary or solo therapy, as opposed to an adjuvant one. Also presented is the relevant literature regarding each of these retinopathies.
February 13, 2019: European Journal of Ophthalmology
https://read.qxmd.com/read/30757913/comparison-of-aflibercept-and-ranibizumab-in-diabetic-macular-edema-associated-with-subretinal-detachment
#2
Abdullah Ozkaya, Gokhan Demir, Asli Kirmaci
PURPOSE: To compare the efficacy of ranibizumab and aflibercept in the treatment of diabetic macular edema associated with subfoveal retinal detachment. METHODS: This is a retrospective, comparative study. The treatment-naïve diabetic macular edema patients who had diabetic macular edema associated with subfoveal retinal detachment and underwent intravitreal aflibercept or intravitreal ranibizumab treatment were included. The patients were treated on a pro re nata treatment regimen after a loading dose of 3-monthly injections and the follow-up time was 12 months...
February 13, 2019: European Journal of Ophthalmology
https://read.qxmd.com/read/30755034/the-effect-of-alternate-occlusion-on-control-of-intermittent-exotropia-in-children
#3
Mohammad Reza Akbari, Ali Mirzajani, Mohammad Reza Moeinitabar, Arash Mirmohammadsadeghi, Masoud Khorrami-Nejad, Leila Sharbatoghli
PURPOSE: The aim is to investigate the effect of alternate occlusion on control of intermittent exotropia in children 3 to 8 years old. METHODS: The ability of 28 children to control of the deviation at far and near was evaluated based on 3-point and 6-point control scales. Stereopsis and fusion were assessed using the Titmus and Worth 4-dot tests, respectively. Two-hour alternate daily occlusion was prescribed for children with no dominancy. For children with a dominant eye, 2-h occlusion of the dominant eye for 5 days and the non-dominant eye for 2 days...
February 12, 2019: European Journal of Ophthalmology
https://read.qxmd.com/read/30747005/delays-in-uptake-of-surgery-for-childhood-cataract-at-a-child-eye-health-tertiary-facility-in-sub-saharan-africa
#4
M O Ugalahi, B A Olusanya, O O Fagbemi, A M Baiyeroju
BACKGROUND: Timely uptake of surgery is vital in the control of childhood blindness due to cataract. The aim of this study is to determine the uptake of surgery as well as the frequency and reasons for rescheduling of surgery for childhood cataract in a tertiary hospital in southwest Nigeria. METHODS: A retrospective study of children with childhood cataract seen at the Paediatric Ophthalmology unit of the University College Hospital, Ibadan between 2011 and 2015...
February 12, 2019: European Journal of Ophthalmology
https://read.qxmd.com/read/30739479/comparison-of-visual-and-optical-quality-of-monofocal-versus-multifocal-intraocular-lenses
#5
Irene Altemir-Gomez, Maria S Millan, Fidel Vega, Francisco Bartol-Puyal, Galadriel Gimenez-Calvo, Jose M Larrosa, Vicente Polo, Luis E Pablo, Elena Garcia-Martin
OBJECTIVE: To compare visual quality in patients implanted with Tecnis® monofocal (ZCB00) and multifocal (ZMB00) intraocular lenses taking into account their optical quality measured in vitro with an eye model. METHODS: In total, 122 patients participated in this study: 44 implanted with monofocal and 78 with multifocal intraocular lenses. Measurements of visual acuity and contrast sensitivity were performed. The optical quality of the intraocular lenses was evaluated in three image planes (distance, intermediate and near) using an eye model on a test bench...
February 10, 2019: European Journal of Ophthalmology
https://read.qxmd.com/read/30732462/multimodal-imaging-of-torpedo-maculopathy-including-adaptive-optics
#6
Juliette Hugo, Marie Beylerian, Eric Denion, Aurore Aziz, Pierre Gascon, Danièle Denis, Frédéric Matonti
PURPOSE: The etiology of torpedo maculopathy remains unknown, but it has been recently suggested that it could represent a persistent defect in the development of the retinal pigment epithelium. As retinal pigment epithelium and photoreceptors form a functional unit, an alteration of photoreceptor distribution or function is predictable. The aim of this study is to describe multimodal imaging, including adaptive optics, in three cases of torpedo maculopathy, and discuss its pathogenesis...
February 8, 2019: European Journal of Ophthalmology
https://read.qxmd.com/read/30722695/remote-hydrodissection
#7
Eytan Z Blumenthal, Michael Mimouni
We describe a technique for performing hydrodissection in which the cannula tip is not advanced beyond the capsulorhexis edge, nor embedded into the cortex, but instead is placed within the capsulorhexis boundaries, pointing to the capsulorhexis edge, and angled slightly posterior to it. The fluid stream squirted from the cannula creates a cleavage plane between the capsule and cortex (hydrodissection), with a distinct wave dissecting the posterior capsule off the overlying cortex. By later rotating the angle slightly more posteriorly, hydrodelineation occurs, with the resultant "golden ring," and often, multiple "golden rings...
February 5, 2019: European Journal of Ophthalmology
https://read.qxmd.com/read/30722692/early-scatter-laser-photocoagulation-promotes-the-formation-of-collateral-vessels-in-branch-retinal-vein-occlusion
#8
Seoung Hyun An, Woo Jin Jeong
PURPOSE: To investigate the effect of early-scatter laser photocoagulation on the formation of collateral vessels in branch retinal vein occlusion. METHODS: The medical records of 40 cases (40 patients) of branch retinal vein occlusion with macular edema were retrospectively reviewed. Of them, 23 patients were treated with intravitreal bevacizumab injection and 17 patients underwent intravitreal bevacizumab injection with additional laser treatment. Early-scatter laser photocoagulation was applied for capillary non-perfusion areas, regardless of retinal neovascularization...
February 5, 2019: European Journal of Ophthalmology
https://read.qxmd.com/read/30712383/visual-prognosis-of-posterior-and-combined-persistent-fetal-vasculature
#9
Veronique Promelle, Sophie Bryselbout, Solange Milazzo
INTRODUCTION: The persistent fetal vasculature refers to congenital anomalies of the globe resulting from the abnormal persistence of the hyaloid vascular system. It can present as anterior, posterior, or combined form. The aim of this study was to report the visual outcomes of posterior and combined forms of persistent fetal vasculature. METHODS: This retrospective, single-center study included every patient referred to our outpatient clinic with a posterior or combined form of persistent fetal vasculature...
February 4, 2019: European Journal of Ophthalmology
https://read.qxmd.com/read/30696257/vision-utilities-in-italy-and-the-united-states-comparison-of-time-tradeoff-vision-utilities
#10
Gabriella De Salvo, Gary C Brown, Melissa M Brown
BACKGROUND/AIMS: To compare time tradeoff vision utilities from two developed Western countries to ascertain whether these vision-related, quality-of-life preferences are similar. METHODS: Time tradeoff utilities were acquired from ophthalmology patient populations with ophthalmic pathologic conditions by personal interview in Italy and the United States using a reliable and previously validated, standardized questionnaire. RESULTS: Data from 47 consecutive Italian participants and 325 consecutive American participants were compared...
January 30, 2019: European Journal of Ophthalmology
https://read.qxmd.com/read/30678489/long-term-observation-of-graft-thickness-and-shape-in-descemet-stripping-and-automated-endothelial-keratoplasty
#11
Yi-Ching Hsieh, Chun-Chi Chiang, Yi-Yu Tsai
PURPOSE: To evaluate the thickness and shape of the posterior lamellar graft in Descemet stripping and automated endothelial keratoplasty after long-term observation. METHODS: All patients who underwent Descemet stripping and automated endothelial keratoplasty including simple and triple Descemet stripping and automated endothelial keratoplasty between August 2009 and May 2014 were enrolled in this retrospective study. To assess postoperative thickness and shape of the Descemet stripping and automated endothelial keratoplasty graft, images of the graft taken at the center (C), mid-periphery at 4 mm optical zone (P1), and periphery at 6 mm optical zone (P2) at 1, 2, and 3 years postoperatively were obtained using anterior segment optical coherence tomography...
January 24, 2019: European Journal of Ophthalmology
https://read.qxmd.com/read/30644317/predictors-of-visual-impairment-in-primary-and-secondary-glaucoma-in-a-tertiary-institute-in-north-india
#12
Srishti Raj, Laxmi Prabhavathi Savla, Faisal Thattaruthody, Natasha Gautam Seth, Sushmita Kaushik, Surinder Singh Pandav
AIM: To find out and compare various predictors of glaucoma-related visual impairments in primary and secondary glaucoma. METHODS: A prospective observational study of patients, who were above 30 years of age. They were diagnosed as primary/secondary glaucoma with visual acuity <20/200 Snellen's/visual field showing less than 20° isopter in at least one eye, with a minimum follow-up of one year at a tertiary center. Patients were classified into advanced and end-stage glaucoma and outcome was assessed according to visual acuity and visual fields to see predictors of visual impairments...
January 15, 2019: European Journal of Ophthalmology
https://read.qxmd.com/read/30642195/silicone-oil-droplets-in-repackaged-anti-vascular-endothelial-growth-factors-for-intravitreal-injections-in-search-of-the-main-source-of-contamination
#13
José Luis Olea, María Gómez-Resa, María Mercedes Cervera-Peris, Juan Antonio Aragón
INTRODUCTION: Repackaging of anti-vascular endothelial growth factors in polypropylene syringes lubricated with silicone oil for intravitreal use is associated with the presence of intravitreal silicone oil droplets. The objective of this study is to assess how the use of silicone-free syringes (for storage and/or administration) would reduce the amount of silicone oil droplets in the product to be administered. METHODS: Two 16 mL vials of bevacizumab were repackaged at the compounding pharmacy to obtain four sets of product, each consisting of three 1...
January 15, 2019: European Journal of Ophthalmology
https://read.qxmd.com/read/30642193/igg4-related-dacryocystitis-and-aortitis-a-new-association
#14
Enrique España-Gregori, Miriam Rahhal-Ortuño, Véronique Benavent-Corai, Alex Samir Fernández-Santodomingo, Marina Aguilar-González
A 73-year-old woman with a history of muscular weakness and dyspnoea of unknown etiology was referred to our Ophthalmology Department for dacryocystitis. Lacrimal sac biopsy revealed IgG4 plasma cell infiltration and systemic diagnosis was done based on this, allowing an appropriate treatment to be established. To our knowledge, this is the first reported case of IgG4-related dacryocystitis associated to aortitis.
January 15, 2019: European Journal of Ophthalmology
https://read.qxmd.com/read/30638059/tadeusz-krwawicz-md-the-inventor-of-cryosurgery-in-ophthalmology
#15
Andrzej Grzybowski, Piotr Kanclerz
Tadeusz Krwawicz (1910-1988) pioneered the use of cryosurgery in, as ophthalmology. The idea arose in 1959 while experimenting because on lyophilization to store corneas and lenses for transplantation it was difficult to remove the lens without damage the capsule was usually torn. Subsequent experiments on rabbits revealed that touching the lens with a wire cooled to 203°K (-70°C) resulted in firm attachment of the lens capsule and subcapsular masses. A cryoextractor was developed and employed for clinical use in cataract extraction, likewise in intumescent cataracts and lens subluxation...
January 14, 2019: European Journal of Ophthalmology
https://read.qxmd.com/read/30638053/psoriasis-associated-progressive-necrotizing-posterior-scleritis-a-6-year-follow-up
#16
Radgonde Amer, Nadav Levinger
PURPOSE: Posterior scleritis is the least frequent form of scleritis accounting for around 2%-8% of all scleritis cases. We aim to present the 6-year clinical course of a 62-year-old female patient with bilateral progressive necrotizing posterior scleritis who suffered from concurrent active psoriasis and psoriatic arthritis. METHODS: Descriptive case report. RESULTS: A middle-aged female patient was referred to our clinic because of left eye peripheral progressively enlarging white retinochoroidal lesions...
January 14, 2019: European Journal of Ophthalmology
https://read.qxmd.com/read/30632407/self-measurement-with-icare-home-tonometer-patients-feasibility-and-acceptability
#17
Barbara Cvenkel, Makedonka Atanasovska Velkovska, Vesna Dimovska Jordanova
PURPOSE: To evaluate and compare the accuracy of self-measurement of intraocular pressure using Icare Home rebound tonometer with Goldmann applanation tonometer and assess acceptability of self-tonometry in patients with glaucoma and ocular hypertension. METHODS: In the study, 117 subjects were trained to use Icare Home for self-measurement. Icare Home tonometer readings were compared with Goldmann applanation tonometer, including one eye per patient. Agreement between the two methods of measurement was evaluated by Bland and Altmann analysis...
January 11, 2019: European Journal of Ophthalmology
https://read.qxmd.com/read/30618282/intravitreal-bevacizumab-treatment-for-neovascular-age-related-macular-degeneration-and-thromboembolic-events
#18
Orly Weinstein, Muhammad Abu Tailakh, Tova Lifshitz, Victor Novack, Jaime Levy
BACKGROUND: Systemic complications of intravitreal anti-vascular endothelial growth factor agents are relatively uncommon but highly significant. OBJECTIVES: Primary objective: To assess the risk for thromboembolic events following intravitreal bevacizumab injection in neovascular age-related macular degeneration patients by a large population-based study. Secondary objective: To analyze the association between injection frequency and the risk for thromboembolic events, the time interval between the injection and the thromboembolic events, and the influence of chronic diseases on complications rate...
January 8, 2019: European Journal of Ophthalmology
https://read.qxmd.com/read/30618278/ex-press-mini-shunt-implanted-in-a-pregnant-patient-with-iridocorneal-endothelial-syndrome
#19
Teresa Colás-Tomás, Elena López Tizón
INTRODUCTION: The failure rate of both filtration surgery and of aqueous shunt implantation is higher for iridocorneal endothelial syndrome than in other scenarios, due to the continuous proliferation of abnormal endothelial cells over the trabecular meshwork and the filtration area and also due to the more pronounced cicatrizing response shown by these young patients. We present the first case ever described in the literature of a pregnant patient with iridocorneal endothelial syndrome and uncontrolled ocular hypertension who was implanted an Ex-PRESS mini-shunt...
January 8, 2019: European Journal of Ophthalmology
https://read.qxmd.com/read/30585497/ocular-manifestations-of-hydroa-vacciniforme-in-a-black-child
#20
Roland Höllhumer
PURPOSE: To report the clinical presentation (systemic and ocular) of hydroa vacciniforme in a Black South African child. METHODS: Case report. RESULTS: A 14-year-old Black boy was seen at the corneal service with cutaneous erosions, varioliform scarring, corneal scarring, cicatricial conjunctivitis and central crystalline corneal opacity. CONCLUSION: We report the first case in the literature of ocular hydroa vacciniforme in a young Black South Africa boy...
December 26, 2018: European Journal of Ophthalmology
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