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Ethnicity & Disease

Kristen M George, Aaron R Folsom, Lyn M Steffen, Lynne E Wagenknecht, Thomas H Mosley
Geographic differences in cardiovascular disease (CVD) mortality among African Americans (AAs) are well-established, but not well-characterized. Using the Minnesota Heart Survey (MHS) and Atherosclerosis Risk in Communities (ARIC) Study, we aimed to assess whether CVD risk factors drive geographic disparities in CVD mortality among AAs. ARIC risk factors were measured between1987-1989 from a population-based sample of AAs, aged 45 to 64 years, living in Jackson, MS and Forsyth County, NC. Similar measures were made at MHS baseline, 1985, in AAs from Minneapolis-St...
2019: Ethnicity & Disease
Gloria L Beckles, Kai McKeever Bullard, Sharon Saydah, Giuseppina Imperatore, Fleetwood Loustalot, Adolfo Correa
Objective: We examined whether life course socioeconomic position (SEP) was associated with incidence of type 2 diabetes (t2DM) among African Americans. Design: Secondary analysis of data from the Jackson Heart Study, 2000-04 to 2012, using Cox proportional hazard regression to estimate hazard ratios (HR) with 95% CI for t2DM incidence by measures of life course SEP. Participants: Sample of 4,012 nondiabetic adults aged 25-84 years at baseline...
2019: Ethnicity & Disease
Catherine Duggan, Yamile Molina, Elizabeth Carosso, Genoveva Ibarra, Beti Thompson
Objectives: Latinas are less likely than non-Latina Whites (NLW) to utilize mammographic screening and are more likely to be diagnosed with late-stage breast cancer. Here, we examine the effects of county-level factors on guideline-concordant breast-cancer screening behaviors in Latinas and NLWs. Design: Latinas (N=108) and NLW women (N=132) aged >40 years, residing in two adjacent rural, medically underserved counties in eastern Washington State, completed a baseline questionnaire on mammography utilization and demographics...
2019: Ethnicity & Disease
Monica Webb Hooper, Taghrid Asfar, Marina Unrod, Asha Dorsey, John B Correa, Karen O Brandon, Vani N Simmons, Michael A Antoni, Tulay Koru-Sengul, David J Lee, Thomas H Brandon
Objective: The exclusion criteria of tobacco cessation randomized clinical trials (RCTs) may have unintended consequences on inclusion and cessation disparities. We examined racial/ethnic differences in: a) exclusion from a group-based cessation RCT; and b) reasons for exclusion. Design: Quasi-experimental. Inclusion criteria were self-identification as African American/Black, non-Hispanic White, or Hispanic (any race), adults, minimum five cigarettes/day or carbon monoxide reading of ≥ 8 parts per million (ppm), interest in quitting, and spoke/read English...
2019: Ethnicity & Disease
Paul Archibald
No abstract text is available yet for this article.
2019: Ethnicity & Disease
Marino A Bruce, Keith C Norris, Bettina M Beech, Janice V Bowie, Roland J Thorpe
No abstract text is available yet for this article.
2019: Ethnicity & Disease
Samantha Enstad, Kristin Rankin, Carla Desisto, James W Collins
Objective: To ascertain the association between father's lifetime socioeconomic status (SES) and rates of small for gestational age (SGA, defined as weight for gestational age <10th percentile) and infant mortality (defined as <365 days). Methods: The study sample was limited to the singleton births of African American (n=8,331), non-Latina White (n=18,200), and Latina (n=2,637) women. Stratified and multilevel, multivariable logistic regression analyses were conducted on the Illinois transgenerational dataset of infants (1989-1991) and their Chicago-born parents (1956-1976) with appended US census income data (n=29,168)...
2019: Ethnicity & Disease
Khadijah E Abdallah, Kathleen A Calzone, Jean F Jenkins, Melissa E Moss, Sherrill L Sellers, Vence L Bonham
Objective: The debate over use of race as a proxy for genetic risk of disease continues, but little is known about how primary care providers (nurse practitioners and general internal medicine physicians) currently use race in their clinical practice. Our study investigates primary care providers' use of race in clinical practice. Methods: Survey data from three cross-sectional parent studies were used. A total of 178 nurse practitioners (NPs) and 759 general internal medicine physicians were included...
2019: Ethnicity & Disease
(no author information available yet)
[This corrects the article on p. 60 in vol. 20, PMID: 20521387.].
October 18, 2018: Ethnicity & Disease
Lisa A Cooper
During August 30-31, 2017, the National Heart, Lung, and Blood Institute's Center for Translation Research and Implementation Science (CTRIS) hosted a two-day workshop with thought leaders and experts in the fields of implementation science, prevention science, health inequities research, and training and research workforce development. The workshop addressed critical challenges and compelling questions from the NHLBI Strategic Vision, as well as the Department of Health and Human Services' Action Plan to Reduce Racial and Ethnic Health Disparities...
2018: Ethnicity & Disease
Athena Starlard-Davenport, Alisa Rich, Titilope Fasipe, Eboni I Lance, Kehinde Adekola, Ariadna Forray, Mesia Steed, Ashley Fitzgerald, Scharri Walker, Betty S Pace
In this perspective, we describe our experience as women of color scientists from diverse backgrounds and similar struggles embarking upon the National Heart, Lung and Blood Institute-funded program called PRIDE (Programs to Increase Diversity among Underrepresented Minorities Engaged in Health-Related Research). Under the leadership of our mentor and friend, Betty Pace, MD, a renowned and successful African American physician-scientist, the PRIDE Program was designed to address the difficulties experienced by junior-level minority investigators in establishing independent research programs and negotiating tenure and full professor status at academic institutions...
2018: Ethnicity & Disease
Reina Haque, Xiaoqing Xu, Jiaxiao Shi, Marilyn L Kwan, Rowan T Chlebowski
Background: It is unknown how subsequent breast cancer outcomes vary by biologic subtype and race/ethnicity in a diverse cohort of breast cancer survivors. Methods: We conducted a prospective cohort study of 6,154 insured breast cancer survivors (AJCC TNM stages 0-IV) diagnosed between 1996-2007 and followed them through 1/1/2010 for subsequent breast cancer events (recurrence, contralateral breast cancer, metastasis, mortality). We compared subsequent breast cancer rates by race/ethnicity groups and biologic subtype (luminal A, luminal B, HER2-enriched, and triple negative)...
2018: Ethnicity & Disease
Dame Idossa, Narjust Duma, Katerina Chekhovskiy, Ronald Go, Sikander Ailawadhi
The use of race and ethnicity in biomedical research has been a subject of debate for the past three decades. Initially the two major race categories were: White and Black, leaving other minorities uncounted or inappropriately misclassified. As the science of health disparities evolves, more sophisticated and detailed information has been added to large databases. Despite the addition of new racial classifications, including multi-racial denominations, the quality of the data is limited to the data collection process and other social misconceptions...
2018: Ethnicity & Disease
Neomie C Congello, Deborah Koniak-Griffin
Objective: Global recommendations on physical activity for noncommunicable disease prevention can be promoted using partner support strategies among women of Mexican descent and other ethnicities. Design/Methods: This systematic review utilized a multifaceted ecological approach by focusing comprehensively on community, individual, and social factors influencing physical activity. PubMed, SAGE Publications, EBSCO, ResearchGate, the Cochrane Library and Google Scholar search engines were used to find research on physical activity, with inclusion criteria of Mexican American women, aged ≥ 18 years, comprising at least 50% of study population sizes...
2018: Ethnicity & Disease
Francine C Gachupin, Rene Harbaugh, Alex Amarillas, Frances Cupis, Jason Lockwood, Shanna J Tautolo
Objective: The objective was to identify and treat segments of the local population at greatest risk for viral hepatitis C (HCV) infections. Design: The tribal-based HCV initiatives included community involvement and outreach and HCV data were mined and analyzed. Medical records were reviewed, and new HCV tribal health policies and procedures were developed. Results: A total of 251 tribal members (63.7% male) were diagnosed with HCV and had a positive confirmatory test between the years 2009 and 2014...
2018: Ethnicity & Disease
Gildete Barreto Lopes, Sherman A James, Marcelo Barreto Lopes, Carolina Cartaxo Penalva, Camila Tavares Joau E Silva, Cacia Mendes Matos, Márcia Tereza Silva Martins, Antonio Alberto Lopes
Purpose: John Henryism (JH) is a strong behavioral predisposition to engage in high-effort coping with difficult socioenvironmental stressors. We investigated associations between JH and perceived general health (GH) among maintenance hemodialysis (MHD) patients in a multiracial Brazilian population. Design: The 12-item John Henryism Acting Coping (JHAC) Scale was completed by 525 patients enrolled in The Prospective Study of the Prognosis of Hemodialysis Patients (PROHEMO) in Salvador (Bahia) Brazil...
2018: Ethnicity & Disease
Sina Kianoush, Andrew P DeFilippis, Carlos J Rodriguez, Mahmoud Al Rifai, Emelia J Benjamin, Michael E Hall, Pamela Ouyang, Matthew A Allison, Michael J Blaha
Objective: Smoking is a well-known cardiovascular risk factor associated with weight loss. We aimed to evaluate the association between smoking, serum leptin levels, and abdominal fat. Design: Cross-sectional. Setting: Data from examinations 2 or 3 (2002-2005) of the Multi-Ethnic Study of Atherosclerosis (MESA). Participants: 1,875 asymptomatic, community-dwelling adults. Main Outcome Measures: We used multivariable linear regression models to assess the race/ethnicity-specific associations between smoking, serum loge leptin levels, and computed tomography ascertained abdominal fat...
2018: Ethnicity & Disease
Lovejeet Kaur, Priyanka Rani Garg, Pradeep Kumar Ghosh, Kallur Nava Saraswathy
Background: Impaired homocysteine metabolism (IHM; hyperhomocysteinemia) has been linked with many complex disorders like cardiovascular diseases and immunological disturbances. However, studies understanding IHM in light of pro- and anti- atherogeneic markers like Interleukin-17A & -10 (IL-17A & IL-10) and Forkhead box p3 (Foxp3, a master transcription factor) are scarce. Aim: In our present study, we aimed to understand the relation of IHM with plasma IL-17A and IL-10 levels and Foxp3 mRNA expression in peripheral blood mononuclear cells (PBMCs) from an endogamous population (Jats of Haryana, North India) with high prevalence of IHM without the concurrence of significant adverse cardiovascular outcomes...
2018: Ethnicity & Disease
Samuel W Reinhardt, Adefolakemi Babatunde, Eric Novak, David L Brown
Objective: To examine racial differences in outcomes with coronary computed tomographic angiography (CCTA) vs standard emergency department (ED) evaluation for chest pain. Design: Retrospective analysis of the prospective, randomized, multicenter Rule Out Myocardial Ischemia/Infarction by Computer Assisted Tomography (ROMICAT-II) trial. Setting: ED at nine hospitals in the United States. Participants: 940 patients who were Caucasian or African American (AA) presenting to the ED with chest pain...
2018: Ethnicity & Disease
Gregory A Harshfield, Coral D Hanevold, Allison Jasti, Santu Ghosh, Jennifer Pollock, David Pollock, Frank A Treiber, Yanbin Dong, Varghese George
Objective: To test the hypothesis that Angiotensin II (Ang II) is a contributing factor to the response pattern in African Americans (AAs) who retain rather than excrete sodium during mental stress. Design/Study Participants: Double-blind, randomized, cross-over trial of 87 healthy AAs aged 18 to 50 years. Interventions: The study participants received either a placebo or irbesartan, (150 mg PO), an Ang II receptor antagonist, for seven days prior to stress testing...
2018: Ethnicity & Disease
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