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Ultrasound in Obstetrics & Gynecology | Page 2

Artur Ludwin, Inga Ludwin, Marcela A Coelho Neto, Carolina O Nastri, Bala Bhagavath, Steven R Lindheim, Wellington P Martins
OBJECTIVE: To estimate the differences in frequency of septate uterus diagnosis and the association with infertility and previous miscarriage using three different criteria. METHODS: Secondary data-driven analysis of data from prospective study was performed based on data-set of 261 consecutive women of reproductive age from daily clinical practice in private clinic focused on diagnosis and treatment of congenital uterine malformations. Re-analysis of datasets was performed using following definitions of septate uterus: ASRM-2016, ESHRE/ESGE-2016, and CUME-2018 (Congenital Uterine Malformation by Experts)...
April 11, 2019: Ultrasound in Obstetrics & Gynecology
Fred Ushakov, Adalina Sacco, Elena Andreeva, Stefania Tudorache, Thomas Everett, Anna L David, Pranav P Pandya
OBJECTIVES: To describe a new first trimester sonographic sign associated with open fetal spina bifida ("crash sign") where there is posterior displacement and deformation of the mesencephalon against the occipital bone in the axial view, and to evaluate its clinical usefulness in the first trimester diagnosis of spina bifida. METHODS: This was a retrospective review of patients referred to three fetal medicine centres in the first trimester (11-13+6 weeks) with suspected spina bifida...
April 11, 2019: Ultrasound in Obstetrics & Gynecology
Slavyana Galeva, María Del Mar Gil, Liountmila Konstantinidou, Ranjit Akolekar, Kypros H Nicolaides
OBJECTIVES: To examine factors affecting the failure rate to obtain a result from (cf) DNA testing of maternal blood for fetal trisomies 21, 18 and 13 in singleton and twin pregnancies in the first trimester of pregnancy. METHODS: This was a prospective study in 23,495 singleton and 928 twin pregnancies undergoing screening for fetal trisomies by targeted cfDNA testing at 10+0 -14+1 weeks' gestation. Multivariate regression analysis was used to determine significant predictors of failure to obtain a result after first sampling...
April 11, 2019: Ultrasound in Obstetrics & Gynecology
Ahmed A Nassr, Alireza A Shamshirsaz, Hadi Erfani, Jimmy Espinoza, Magdalena Sanz Cortes, Chester J Koh, David R Roth, Joseph R Angelo, George T Mandy, Michael C Braun, Rodrigo Ruano, Michael A Belfort
OBJECTIVE: Congenital lower urinary tract obstruction (LUTO) is a rare condition with high perinatal mortality and morbidity when associated with severe oligohydramnios or anhydramnios in the second trimester of pregnancy. Severe pulmonary hypoplasia and end-stage renal disease are the underlying causes of poor neonatal outcomes in these cases. However, little is known about the subset of fetal LUTO with a normal amount of amniotic fluid at mid-gestation. The objectives of the current study were to describe the natural history, underlying causes, survival and postnatal renal function outcomes of LUTO with normal amniotic fluid volume during the second trimester of pregnancy...
April 11, 2019: Ultrasound in Obstetrics & Gynecology
Stefano Guerriero, Silvia Ajossa, M Angela Pascual, Ignacio Rodriguez, Alba Piras, Maura Perniciano, Luca Saba, Anna Maria Paoletti, Valerio Mais, Juan Luis Alcazar
OBJECTIVES: Due to the reported high sensitivity and specificity of ultrasound in the detection rate of rectosigmoid (RS) endometriosis when performed by an ultrasonographic (US) expert, this test should be considered a gold standard comparable to laparoscopy. No information is available regarding US soft markers in this disease. The aim of this study was to evaluate the use of US soft markers as "first level" examination in the suspicion of RS endometriosis. METHODS: We included in this prospective study all patients with clinical suspicion of deep endometriosis submitted to ultrasonographic evaluation in our academic center for ultrasonographic diagnosis of endometriosis at the Academic Department of Obstetrics and Gynecology, University of Cagliari, Policlinico Universitario Duilio Casula, Monserrato, Cagliari, Italy from January 2016 to February 2017...
April 11, 2019: Ultrasound in Obstetrics & Gynecology
Ilan E Timor-Tritsch, Christine E Foley, Caroline Brandon, Esther Yoon, Jeannine Ciaffarrano, Ana Monteagudo, Kushbakhat Mittal, Leslie Boyd
OBJECTIVE: Accurate diagnosis of borderline ovarian tumors (BOTs) is important to ensure timely and appropriate management, especially in women desiring to preserve fertility. Transvaginal ultrasound (TVUS) is considered the best modality to diagnose adnexal tumors. Sonographic features of BOTs described in the literature include septa, solid components, mural nodules (papillae) and blood vessels within these structures. However, there is no single signature that differentiates BOTs from other adnexal masses...
April 4, 2019: Ultrasound in Obstetrics & Gynecology
Erdogan Nohuz, Olivier Rivière, Karen Coste, Françoise Vendittelli
OBJECTIVE: To assess whether prenatal identification of small-for-gestational-age (SGA) fetuses would reduce the rates of the primary composite outcome of 'stillbirths and neonatal complications', and secondary outcomes of stillbirth and low 5-min Apgar score. METHODS: This historical cohort study was conducted with women who had singleton delivery (≥ 32 weeks), in 247 French maternity units. Medical terminations of pregnancy, infants with malformations, and women with missing delivery data were excluded...
April 4, 2019: Ultrasound in Obstetrics & Gynecology
Jaroslaw Beta, Naila Khan, Ahmed Khalil, Magdalena Fiolna, Ghada Ramadan, Ranjit Akolekar
OBJECTIVES: To determine accurate estimates of maternal and neonatal risks of fetal macrosomia by undertaking a systematic review and meta-analysis METHODS: A search of MEDLINE, EMBASE, CINHAL and The Cochrane Library was performed to review relevant citations reporting maternal and neonatal complications of pregnancies with macrosomia with birthweight (BW) >4,000g and >4,500g. We selected prospective and retrospective cohort and population studies that provided data regarding both, cases and controls...
April 2, 2019: Ultrasound in Obstetrics & Gynecology
Jaroslaw Beta, Naila Khan, Magdalena Fiolna, Ahmed Khalil, Ghada Ramadan, Ranjit Akolekar
OBJECTIVE: To estimate risks of maternal and neonatal complications in pregnancies with macrosomia. METHOD: This was a retrospective cohort study undertaken at a large maternity unit in United Kingdom between January 2009-December 2016. We compared the incidence of complications in pregnancies with macrosomia, defined by birthweight (BW)>4,000 g and severe macrosomia with BW>4,500 g, to those in pregnancies with normal BW 2,500-4,000 g. Regression analysis was undertaken to determine odds ratios (OR) [95% confidence interval (CI)] for pregnancy complications in macrosomic compared to normal BW group...
April 2, 2019: Ultrasound in Obstetrics & Gynecology
Maria Schøler Nørgaard, Ritu Mogra, Jason Pinner, Karl Oliver Kagan, Mette Warming Jørgensen, Vibike Gjørup, Olav Bjørn Petersen, Puk Sandager, Ida Vogel
This is a description of similar prenatal ultrasound findings in five cases of fetal Costello syndrome from 3 countries. We suggest that Costello syndrome (CS) may be recognizable prenatally, is more prevalent in utero than previously described, and that cases diagnosed prenatally have a more severe phenotype and a high risk of intrauterine death compared with cases diagnosed postnatally. This article is protected by copyright. All rights reserved.
April 2, 2019: Ultrasound in Obstetrics & Gynecology
Chris Abousleiman, Aurore Lismonde, Jacques C Jani
The high performance of cell-free DNA (cfDNA) analysis of maternal blood in screening for trisomies 21, 18 and 13 in high- and low-risk pregnancies in now well established.1 In May 2017, our Minister of Public Health announced the reimbursement of non-invasive prenatal testing (NIPT) as a first-line screening tool for all pregnant women in Belgium. Patients have to pay 8.68 € out of their pocket. The decision took effect on the 1st of July 2017. Prior to the above announcement, the National Advisory Committee on Bioethics was asked to give its opinion on ethical issues that NIPT could raise, notably in matters of informed consent and patient counseling...
April 2, 2019: Ultrasound in Obstetrics & Gynecology
B A Virgilio, I D E Blasis, P Sladkevicius, F Moro, G F Zannoni, D Arciuolo, F Mascilini, F Ciccarone, D Timmerman, Kaijser J, R Fruscio, C V A N Holsbeke, D Franchi, E Epstein, F P G Leone, S Guerriero, A Czekierdowski, G Scambia, A C Testa, L Valentin
OBJECTIVES: To describe the clinical and ultrasound characteristics of serous cystadenofibromas in the adnexa. METHODS: This is a retrospective study. From the International ovarian tumor analysis (IOTA) database we identified patients with a histological diagnosis of serous cystadenofibroma, who had undergone preoperative ultrasound examination by an experienced ultrasound examiner between 1999 and 2012. In the IOTA database containing prospectively collected data, the tumors were described using the terms and definitions of the International Ovarian Tumor Analysis (IOTA) group...
April 1, 2019: Ultrasound in Obstetrics & Gynecology
Agnieszka Glazewska-Hallin, Lisa Story, Natalie Suff, Andrew Shennan
Preterm deliveries have multiple aetiologies and management is dependent on cause. Recent studies have shown that caesarean sections performed late in labour have been associated with recurrent, early premature births and late miscarriages (Figure 1). Both the prediction and management of these under-recognised high-risk cases needs to be elucidated. This article is protected by copyright. All rights reserved.
April 1, 2019: Ultrasound in Obstetrics & Gynecology
W M Dooley, P Chaggar, L V De Braud, C Bottomley, E Jauniaux, D Jurkovic
OBJECTIVES: The aim of this study was to assess the overall accuracy of the transvaginal ultrasound scan (TVS) diagnosis of all types of extrauterine ectopic pregnancy (EUEP) in a large group of women who were managed surgically. We also examined the positive predictive value (PPV) of the different ultrasound morphological types of EUEP, using visual confirmation of ectopic pregnancy on surgery as the reference standard. METHODS: We performed a retrospective observational study of all pregnant women who underwent emergency surgery following ultrasound diagnosis of EUEP in a single Early Pregnancy Unit between January 2009 and December 2017...
April 1, 2019: Ultrasound in Obstetrics & Gynecology
Yiu Man Chan, Kwok Ming Law, Liona Chiu Yee Poon, Ho Ming Luk, Yvonne Kwun Yue Cheng, Tak Yeung Leung
Retroesophageal (RE) left brachiocephalic vein (LBCV) is rare. It takes an anomalous route to run posteriorly behind the trachea and esophagus before draining into the superior vena cava via the azygos vein (Figure 1). Isolated RELBCV causes no symptoms. Seven postnatal and six prenatal cases have been reported1,2,3,4,5 , and here we add four more prenatal cases to the list (Table 1). Among the 17 reported cases of RELBCV, five had genetic anomalies, including three RASopathies (Case 2,4,8), one 22q11.2 microdeletion syndrome (Case 1) and one complex chromosomal abnormality (Case 9)...
April 1, 2019: Ultrasound in Obstetrics & Gynecology
Raigam Jafet Martinez-Portilla, Jana Lopez-Felix, Ameth Hawkins-Villareal, Jose Rafael Villafan-Bernal, Fernanda Paz Y Miño, Francesc Figueras, Antoni Borrell
OBJECTIVE: To evaluate the performance of Doppler studies using the middle cerebral artery peak systolic velocity (MCA-PSV) for the prediction of moderate-severe fetal anemia, in untransfused and transfused fetuses. METHODS: A systematic search was performed to identify relevant observational studies evaluating the performance of MCA-PSV using a 1.5 MoM threshold for the prediction of fetal anemia reported in the 2008-2018 period. The reference standard was the diagnosis of fetal anemia by blood sampling...
April 1, 2019: Ultrasound in Obstetrics & Gynecology
Anca Ciobanu, Christos Anthoulakis, Argyro Syngelaki, Ranjit Akolekar, Kypros H Nicolaides
OBJECTIVE: To assess the additive value of fetal growth velocity between 32 and 36 weeks' gestation on the performance of ultrasonographic estimated fetal weight (EFW) at 35+0 - 36+6 weeks' gestation for prediction of small for gestational age (SGA) neonates and adverse perinatal outcome. METHODS: This was a prospective study of 14,497 singleton pregnancies that had undergone routine ultrasound examination at 30+0 - 34+6 and at 35+0 - 36+6 weeks' gestation. Multivariable logistic regression analysis was used to determine whether addition of growth velocity, defined by a difference in EFW and abdominal circumference (AC) Z-scores between the early and late third trimester scans divided by the time interval between them, improved the performance of EFW at 35+0 - 36+6 weeks in the prediction of first, delivery of SGA neonates with birthweight <10th and <3rd percentiles within two weeks and at any stage after assessment and second, composite of adverse perinatal outcome defined as stillbirth, neonatal death or admission to the neonatal unit for ≥48 hours...
March 26, 2019: Ultrasound in Obstetrics & Gynecology
M Ludovisi, F Moro, T Pasciuto, S Di Noi, S Giunchi, L Savelli, M A Pascual, P Sladkevicius, J L Alcazar, D Franchi, R Mancari, M C Moruzzi, D Jurkovic, V Chiappa, S Guerriero, C Exacoustos, E Epstein, P Frühauf, D Fischerova, R Fruscio, F Ciccarone, G F Zannoni, G Scambia, L Valentin, A C Testa
OBJECTIVE: To describe the clinical and ultrasound characteristics of uterine sarcomas. METHODS: This is a retrospective multicenter study. From the databases of 13 ultrasound centers, we identified patients with a histological diagnosis of uterine sarcoma with available ultrasound reports and ultrasound images who had undergone preoperative ultrasound examination between 1996 and 2016. As a first step, each author collected information from the original ultrasound reports on predefined ultrasound features of the tumors from his/her own center and by checking the ultrasound images to find information on variables not described in the original report...
March 25, 2019: Ultrasound in Obstetrics & Gynecology
Jennifer Cohen, Stéphanie Levasseur, Lynn Simpson, Russell Miller, Lindsay Freud
INTRODUCTION: Lower urinary tract obstruction (LUTO) in the fetus may result in massive bladder distention, renal dysfunction, oligohydramnios, and lung hypoplasia. The hemodynamic impact of this pathophysiology has not been well-described. METHODS: We included fetuses diagnosed with severe LUTO with giant bladder and with at least one fetal echocardiogram performed at our center from January 2005 to May 2018. Fetuses with major congenital heart disease were excluded...
March 25, 2019: Ultrasound in Obstetrics & Gynecology
D Paladini, G Donarini, A Rossi
Fetal isolated mild ventriculomegaly (IMV) is a relatively common condition, complicating 1% of all pregnancies. This article is protected by copyright. All rights reserved.
March 25, 2019: Ultrasound in Obstetrics & Gynecology
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