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Journals Journal of Psychiatry & Neuros...

Journal of Psychiatry & Neuroscience : JPN

https://read.qxmd.com/read/37857415/does-serotonin-matter-in-depression
#21
EDITORIAL
Paul R Albert, Pierre Blier
No abstract text is available yet for this article.
2023: Journal of Psychiatry & Neuroscience: JPN
https://read.qxmd.com/read/37857414/correlation-of-the-methylomic-signature-of-smoking-during-pregnancy-with-clinical-traits-in-adhd
#22
JOURNAL ARTICLE
Boris Chaumette, Natalie Grizenko, Weam Fageera, Marie-Ève Fortier, Marina Ter-Stepanian, Aurelie Labbe, Ridha Joober
BACKGROUND: Attention deficit/hyperactivity disorder (ADHD) is a highly prevalent childhood disorder. Maternal smoking during pregnancy is a replicated environmental risk factor for this disorder. It is also a robust modifier of gene methylation during the prenatal developmental period. In this study, we sought to identify loci differentially methylated by maternal smoking during pregnancy and relate their methylation levels to various behavioural and physical outcomes relevant to ADHD...
2023: Journal of Psychiatry & Neuroscience: JPN
https://read.qxmd.com/read/37857413/should-perception-of-emotions-be-classified-according-to-threat-detection-rather-than-emotional-valence-an-updated-meta-analysis-for-a-whole-brain-atlas-of-emotional-faces-processing
#23
JOURNAL ARTICLE
Steve Lukito, Lydia Fortea, Federica Groppi, Ksenia Zuzanna Wykret, Eleonora Tosi, Vincenzo Oliva, Stefano Damiani, Joaquim Radua, Paolo Fusar-Poli
BACKGROUND: Human navigation of social interactions relies on the processing of emotion on faces. This meta-analysis aimed to produce an updated brain atlas of emotional face processing from whole-brain studies based on a single emotional face-viewing paradigm (PROSPERO CRD42022251548). METHODS: We conducted a systematic literature search of Embase, MEDLINE and PsycINFO from May 2008 to October 2021. We used seed-based d mapping with permutation of subject images to conduct a quantitative meta-analysis of functional neuroimaging contrasts between emotional (e...
2023: Journal of Psychiatry & Neuroscience: JPN
https://read.qxmd.com/read/37751919/changes-to-hypothalamic-volume-and-associated-subunits-during-gender-affirming-hormone-therapy
#24
JOURNAL ARTICLE
Melisande E Konadu, Murray B Reed, Ulrike Kaufmann, Patricia A Handschuh, Benjamin Spurny-Dworak, Manfred Klöbl, Clemens Schmidt, Godber, M Godbersen, Elisa Briem, René Seiger, Pia Baldinger-Melich, Georg S Kranz, Rupert Lanzenberger, Marie Spies
BACKGROUND: Among its pleiotropic properties, gender-affirming hormone therapy (GHT) affects regional brain volumes. The hypothalamus, which regulates neuroendocrine function and associated emotional and cognitive processes, is an intuitive target for probing GHT effects. We sought to assess changes to hypothalamus and hypothalamic subunit volumes after GHT, thereby honouring the region's anatomical and functional heterogeneity. METHODS: Individuals with gender dysphoria and cisgender controls underwent 2 MRI measurements, with a median interval of 145 days (interquartile range [IQR] 128...
2023: Journal of Psychiatry & Neuroscience: JPN
https://read.qxmd.com/read/37751918/history-of-abuse-is-not-predictive-of-eating-disorders-with-binge-eating-episodes-but-posttraumatic-stress-disorder-is
#25
LETTER
Timothy D Brewerton
No abstract text is available yet for this article.
2023: Journal of Psychiatry & Neuroscience: JPN
https://read.qxmd.com/read/37751917/heritability-of-amygdala-reactivity-to-angry-faces-and-its-replicable-association-with-the-schizophrenia-risk-locus-of-mir-137
#26
JOURNAL ARTICLE
Tiziana Quarto, Annalisa Lella, Pasquale Di Carlo, Antonio Rampino, Vittoria Paladini, Marco Papalino, Raffaella Romano, Leonardo Fazio, Daniela Marvulli, Teresa Popolizio, Giuseppe Blasi, Giulio Pergola, Alessandro Bertolino
BACKGROUND: Among healthy participants, the interindividual variability of brain response to facial emotions is associated with genetic variation, including common risk variants for schizophrenia, a heritable brain disorder characterized by anomalies in emotion processing. We aimed to identify genetic variants associated with heritable brain activity during processing of facial emotions among healthy participants and to explore the impact of these identified variants among patients with schizophrenia...
2023: Journal of Psychiatry & Neuroscience: JPN
https://read.qxmd.com/read/37673436/common-and-disorder-specific-cortical-thickness-alterations-in-internalizing-externalizing-and-thought-disorders-during-early-adolescence-an-adolescent-brain-and-cognitive-development-study
#27
JOURNAL ARTICLE
Gechang Yu, Zhaowen Liu, Xinran Wu, Benjamin Becker, Kai Zhang, Huaxin Fan, Songjun Peng, Nanyu Kuang, Jujiao Kang, Guiying Dong, Xing-Ming Zhao, Gunter Schumann, Jianfeng Feng, Barbara J Sahakian, Trevor W Robbins, Lena Palaniyappan, Jie Zhang
BACKGROUND: A growing body of neuroimaging studies has reported common neural abnormalities among mental disorders in adults. However, it is unclear whether the distinct disorder-specific mechanisms operate during adolescence despite the overlap among disorders. METHODS: We studied a large cohort of more than 11 000 preadolescent (age 9-10 yr) children from the Adolescent Brain and Cognitive Development cohort. We adopted a regrouping approach to compare cortical thickness (CT) alterations and longitudinal changes between healthy controls ( n = 4041) and externalizing ( n = 1182), internalizing ( n = 1959) and thought disorder ( n = 347) groups...
2023: Journal of Psychiatry & Neuroscience: JPN
https://read.qxmd.com/read/37673435/transcript-levels-of-4-genes-in-umbilical-cord-blood-are-predictive-of-later-autism-development-a-longitudinal-follow-up-study
#28
JOURNAL ARTICLE
Qingzheng Jia, Huilin Li, Min Wang, Chongxia Wei, Lichao Xu, Lin Ye, Chunjun Wang, Shaofeng Ke, Ling Li, Paul Yao
BACKGROUND: Over recent decades, autism spectrum disorder (ASD) has been of increasing epidemiological importance, given the substantial increase in its prevalence; at present, clinical diagnosis is possible only after 2 years of age. In this study, we sought to develop a potential predictive model for ASD screening. METHODS: We conducted a longitudinal follow-up study of newborns over 3 years. We measured transcript levels of 4 genes (superoxide dismutase-2 [ SOD2 ], retinoic acid-related orphan receptor-α [ RORA ], G protein-coupled estrogen receptor-1 [ GPER ], progesterone receptor [ PGR ]), 2 oxidative stress markers and epigenetic marks at the RORA promoter in case-control umbilical cord blood mononuclear cell (UCBMC) samples...
2023: Journal of Psychiatry & Neuroscience: JPN
https://read.qxmd.com/read/37673434/favourable-cognitive-changes-observed-with-metabolic-improvements-in-a-patient-with-severe-mental-illness
#29
JOURNAL ARTICLE
Emma A van Reekum, Nicolette Stogios, Leah Burton, Harold Spivak, Margaret Hahn, Sri Mahavir Agarwal
No abstract text is available yet for this article.
2023: Journal of Psychiatry & Neuroscience: JPN
https://read.qxmd.com/read/37643803/clusters-of-psychosis-compensation-as-a-contributor-to-the-heterogeneity-of-schizophrenia
#30
EDITORIAL
Lena Palaniyappan
No abstract text is available yet for this article.
2023: Journal of Psychiatry & Neuroscience: JPN
https://read.qxmd.com/read/37643802/brain-network-structural-connectome-abnormalities-among-youth-with-attention-deficit-hyperactivity-disorder-at-varying-risk-for-bipolar-i-disorder-a-cross-sectional-graph-based-magnetic-resonance-imaging-study
#31
JOURNAL ARTICLE
Ziyu Zhu, Du Lei, Kun Qin, Xiuli Li, Wenbin Li, Maxwell J Tallman, L Rodrigo Patino, David E Fleck, Veronica Aghera, Qiyong Gong, John A Sweeney, Robert K McNamara, Melissa P DelBello
BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is highly prevalent among youth with or at familial risk for bipolar-I disorder (BD-I), and ADHD symptoms commonly precede and may increase the risk for BD-I; however, associated neuropathophysiological mechanisms are not known. In this cross-sectional study, we sought to investigate brain structural network topology among youth with ADHD, with and without familial risk of BD-I. METHODS: We recruited 3 groups of psychostimulant-free youth (aged 10-18 yr), namely youth with ADHD and at least 1 biological parent or sibling with BD-I (high-risk group), youth with ADHD who did not have a first- or second-degree relative with a mood or psychotic disorder (low-risk group) and healthy controls...
2023: Journal of Psychiatry & Neuroscience: JPN
https://read.qxmd.com/read/37643801/classifying-youth-with-bipolar-disorder-versus-healthy-youth-using-cerebral-blood-flow-patterns
#32
JOURNAL ARTICLE
Nicholas J Luciw, Anahit Grigorian, Mikaela K Dimick, Guocheng Jiang, J Jean Chen, Simon J Graham, Benjamin I Goldstein, Bradley J MacIntosh
BACKGROUND: Clinical neuroimaging studies often investigate group differences between patients and controls, yet multivariate imaging features may enable individual-level classification. This study aims to classify youth with bipolar disorder (BD) versus healthy youth using grey matter cerebral blood flow (CBF) data analyzed with logistic regressions. METHODS: Using a 3 Tesla magnetic resonance imaging (MRI) system, we collected pseudo-continuous, arterial spin-labelling, resting-state functional MRI (rfMRI) and T 1 -weighted images from youth with BD and healthy controls...
2023: Journal of Psychiatry & Neuroscience: JPN
https://read.qxmd.com/read/37607825/decreased-gaba-ratios-referenced-to-creatine-and-phosphocreatine-in-the-left-dorsolateral-prefrontal-cortex-of-females-of-reproductive-age-with-major-depression
#33
JOURNAL ARTICLE
Kim H Tran, Jessica Luki, Sarah Hanstock, Christopher C Hanstock, Peter Seres, Katherine Aitchison, Jean-Michel Le Melledo
BACKGROUND: It has been suggested that the dorsolateral prefrontal cortex (DLPFC), especially the left DLPFC, has an important role in the pathophysiology and the treatment of major depressive disorder (MDD); furthermore, the contributory and antidepressant role of γ-aminobutyric acid (GABA) is increasingly recognized. Given that most female patients with MDD are of reproductive age, we sought to assess in vivo baseline GABA levels in the left DLPFC among unmedicated females of reproductive age with depression...
2023: Journal of Psychiatry & Neuroscience: JPN
https://read.qxmd.com/read/37437921/abnormal-cerebral-metabolism-and-metabolic-connectivity-in-individuals-with-heroin-dependence-an-integrated-resting-state-pet-fmri-study-in-large-scale-networks
#34
JOURNAL ARTICLE
Long Jin, Menghui Yuan, Jiajie Chen, Wei Zhang, Lei Wang, Yixin Wei, Yunbo Li, Zhirui Guo, Wei Wang, Longxiao Wei, Qiang Li
BACKGROUND: Increasing evidence suggests that heroin addiction may be related to the dysfunction among the triple brain network (default mode network [DMN], salience network [SN] and executive control network [ECN]). However, the characteristics of glucose metabolism and metabolic connectivity among core regions of the triple brain network remain unknown. Therefore, we hypothesized that individuals with heroin dependence would show abnormal glucose metabolism and accompanied abnormal metabolic connectivity within the triple brain network...
2023: Journal of Psychiatry & Neuroscience: JPN
https://read.qxmd.com/read/37437920/involvement-of-nucleus-accumbens-d2-medium-spiny-neurons-projecting-to-the-ventral-pallidum-in-anxiety-like-behaviour
#35
JOURNAL ARTICLE
Raquel Correia, Bárbara Coimbra, Ana Verónica Domingues, Marcelina Wezik, Natacha Vieitas-Gaspar, Rita Gaspar, Nuno Sousa, Luísa Pinto, Ana João Rodrigues, Carina Soares-Cunha
BACKGROUND: The nucleus accumbens (NAcc) is a crucial brain region for emotionally relevant behaviours. The NAcc is mainly composed of medium spiny neurons (MSNs) expressing either dopamine receptor D1 (D1-MSNs) or D2 (D2-MSNs). The D1-MSNs project to the ventral tegmental area (VTA) and the ventral pallidum (VP), whereas the D2-MSNs project only to the VP. The D1- and D2-MSNs have been associated with depression-like behaviours, but their contribution to anxiety remains to be determined...
2023: Journal of Psychiatry & Neuroscience: JPN
https://read.qxmd.com/read/37402580/collaborative-discontinuation-of-antipsychotics-after-the-first-episode-of-psychosis
#36
JOURNAL ARTICLE
Theo Korchia, Hani Abdelhafez, Alice Bretelle, Ridha Joober, Lena Palaniyappan
No abstract text is available yet for this article.
2023: Journal of Psychiatry & Neuroscience: JPN
https://read.qxmd.com/read/37402579/characterizing-and-detecting-delirium-with-clinical-and-computational-measures-of-speech-and-language-disturbance
#37
JOURNAL ARTICLE
Sunny X Tang, Yan Cong, Gwenyth Mercep, Mutahira Bhatti, Grace Serpe, Valeria Gromova, Sarah Berretta, Majnu John, Mark Y Liberman, Liron Sinvani
BACKGROUND: Delirium is a critically underdiagnosed syndrome of altered mental status affecting more than 50% of older adults admitted to hospital. Few studies have incorporated speech and language disturbance in delirium detection. We sought to describe speech and language disturbances in delirium, and provide a proof of concept for detecting delirium using computational speech and language features. METHODS: Participants underwent delirium assessment and completed language tasks...
2023: Journal of Psychiatry & Neuroscience: JPN
https://read.qxmd.com/read/37402578/improving-causality-perception-judgments-in-schizophrenia-spectrum-disorder-via-transcranial-direct-current-stimulation
#38
JOURNAL ARTICLE
Rasmus Schülke, Christina V Schmitter, Benjamin Straube
BACKGROUND: Deficient causality perception and attribution may underlie key symptoms of schizophrenia spectrum disorder (SSD), such as delusions and ideas of reference. Although transcranial direct current stimulation (tDCS) can increase the influence of spatial information on perceptual causality judgments among healthy participants, its effect among patients with SSD remains unknown. We sought to determine whether tDCS modulates the contribution of stimulus characteristics to perceptual causality judgments among patients with SSD; we predicted that right parietal tDCS would increase the influence of spatial stimulus characteristics on patients' causality perception...
2023: Journal of Psychiatry & Neuroscience: JPN
https://read.qxmd.com/read/37339818/from-research-of-mental-disorders-to-clinical-application-lessons-from-diabetes
#39
EDITORIAL
Georg Northoff
No abstract text is available yet for this article.
2023: Journal of Psychiatry & Neuroscience: JPN
https://read.qxmd.com/read/37339817/real-time-functional-magnetic-resonance-imaging-neurofeedback-training-of-amygdala-upregulation-increases-affective-flexibility-in-depression
#40
JOURNAL ARTICLE
Laurie Compère, Greg J Siegle, Sair Lazzaro, Marlene Strege, Gia Canovali, Scott Barb, Theodore Huppert, Kymberly Young
BACKGROUND: Decreased affective flexibility is associated with depression symptoms, and it has been suggested that common interventions may target this mechanism. To explore this hypothesis, we evaluated whether real-time functional magnetic resonance imaging neurofeedback (rtfMRI-nf) training to increase the amygdala responses during positive memory recall resulted in both symptom improvements, as has been observed previously, and flexibility to decrease amygdala reactivity in response to a cognitive task among patients with major depressive disorder (MDD)...
2023: Journal of Psychiatry & Neuroscience: JPN
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