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Journal of Investigational Allergology & Clinical Immunology

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https://read.qxmd.com/read/30977465/ebastine-in-the-treatment-of-allergic-rhinitis-and-urticaria-30-years-of-clinical-studies-and-real-world-experience
#1
REVIEW
J Sastre
Histamine, acting predominantly via the H1-receptor, is an important mediator of the symptoms of allergy, and H1-antihistamines, which stabilise the receptor in its inactive form, are the treatment of choice for some chronic allergic conditions. Ebastine is a well-established oral second-generation H1-antihistamine. It is administered once daily at a dose of 10-20 mg and is available as a standard tablet and also as a fast-dissolving tablet that disintegrates in the mouth. Ebastine has demonstrated to be efficacious at relieving symptoms in patients with allergic rhinitis or urticaria in multiple clinical trials...
April 12, 2019: Journal of Investigational Allergology & Clinical Immunology
https://read.qxmd.com/read/30969172/selection-of-biologics-in-severe-asthma-a-multifaceted-algorithm
#2
I Dávila, S Quirce, J M Olaguibel
No abstract text is available yet for this article.
April 10, 2019: Journal of Investigational Allergology & Clinical Immunology
https://read.qxmd.com/read/30957763/impact-of-low-dose-chlorine-inhalation-in-healthy-humans-a-pilot-study
#3
I Ojanguren, S Chaboillez, Y Cloutier, A Panariti, T K McGovern, J G Martin, C Lemiere
No abstract text is available yet for this article.
April 8, 2019: Journal of Investigational Allergology & Clinical Immunology
https://read.qxmd.com/read/30957762/der-p-23-clinical-relevance-of-molecular-monosensitisation-in-house-dust-mite-allergy
#4
F Matos Semedo, Y Dorofeeva, A P Pires, E Tomaz, L Taborda Barata, F Inácio, R Valenta
No abstract text is available yet for this article.
April 8, 2019: Journal of Investigational Allergology & Clinical Immunology
https://read.qxmd.com/read/30957761/angioedema-induced-by-nonsteroidal-anti-inflammatory-drugs-a-genotype-phenotype-correlation-in-a-brazilian-population
#5
L F Ensina, R P Martin, R Filippelli-Silva, C Lopes Veronez, D Sole, J Bosco Pesquero
No abstract text is available yet for this article.
April 8, 2019: Journal of Investigational Allergology & Clinical Immunology
https://read.qxmd.com/read/30957760/anaphylaxis-to-clavulanic-acid-seven-year-survey
#6
A M Silveira, A Gaspar, F Benito-Garcia, S Couto, J Matias, M Chambel, M Morais-Almeida
No abstract text is available yet for this article.
April 8, 2019: Journal of Investigational Allergology & Clinical Immunology
https://read.qxmd.com/read/30957759/a-reoccurring-drug-induced-liver-injury-dili-with-cetirizine-and-amoxicillin-clavulanate-potassium
#7
G Vilà-Nadal, R Lleonart Bellfill, J Martí Garrido, C Baliellas Comellas, M Corominas Sánchez
No abstract text is available yet for this article.
April 8, 2019: Journal of Investigational Allergology & Clinical Immunology
https://read.qxmd.com/read/30957758/occupational-asthma-caused-by-powder-paint-in-the-automotive-industry
#8
A Tiotiu, I Thaon, M Poussel, E Penven
No abstract text is available yet for this article.
April 8, 2019: Journal of Investigational Allergology & Clinical Immunology
https://read.qxmd.com/read/30957757/usefulness-of-omalizumab-and-sting-challenge-test-in-hymenoptera-venom-allergy-and-mastocytosis
#9
D González-de-Olano, M A Padial-Vilchez, B Núñez-Acevedo, M P de-Calzada-Bustingorri, A de-Andrés-Martín, C Caldas, M Piris-Villaespesa, B de-la-Hoz-Caballer
No abstract text is available yet for this article.
April 8, 2019: Journal of Investigational Allergology & Clinical Immunology
https://read.qxmd.com/read/30931919/diagnostic-approach-for-suspected-allergic-cutaneous-reaction-to-a-permanent-tattoo
#10
REVIEW
J F Silvestre, I González-Villanueva
The last few decades have seen a notable increase in the number of people who have a tattoo. This practice is not free from complications. Most adverse effects appear early and are temporary, although they can occasionally develop later and be permanent and serious. Recent research has generated new knowledge on the composition of inks, their degradation over time, the immune activity that is stimulated, and the various clinical disorders that can arise. This information enables better approaches to diagnosis and management when complications arise...
April 1, 2019: Journal of Investigational Allergology & Clinical Immunology
https://read.qxmd.com/read/30931918/referral-criteria-for-asthma-consensus-document
#11
REVIEW
M Blanco Aparicio, J Delgado Romero, J Molina París, J Tomás Gómez, F Gómez Ruiz, F J Álvarez Gutiérrez, J Domínguez Ortega, S Núñez Palomo, A Hidalgo Requena, D A Vargas Ortega, M J Álvarez Puebla, J A Carretero Gracia
Asthma is one of the most prevalent chronic diseases in Spain. Current treatments ensure that the disease is controlled in most cases. However, disease is often uncontrolled in daily clinical practice, mainly owing to underdiagnosis, loss to follow-up, and poor adherence to therapy. In order to improve this situation, we must coordinate all those health professionals who intervene in patient care. Therefore, the Spanish Society of Allergology and Clinical Immunology (SEAIC), the Spanish Society of Primary Care Physicians (SEMERGEN), the Spanish Society of Family and Community Medicine (semFYC), the Spanish Society of General and Family Physicians (SEMG), and the Spanish Society of Pneumology and Thoracic Surgery (SEPAR) have drawn up a consensus document in which they establish criteria for referral and guidelines for the diagnosis, control, and follow-up of patients with asthma...
April 1, 2019: Journal of Investigational Allergology & Clinical Immunology
https://read.qxmd.com/read/30931917/omalizumab-s-effectiveness-in-severe-allergic-asthma-and-nasal-polyps-a-real-life-study
#12
A Tiotiu, J P Oster, P Roux, P L Nguyen Thi, G Peiffer, P Bonniaud, J C Dalphin, F de Blay
BACKGROUND AND OBJECTIVE: Omalizumab is a human anti-IgE antibody approved for the treatment of severe allergic asthma (SAA), but its effectiveness when a chronic rhinosinusitis with nasal polyposis (CRSNP+) is associated is less documented. Objective: The aim of this study was to evaluate in real-life the effectiveness of omalizumab in patients with SAA and CRSNP+ with or without aspirin intolerance. METHODS: A retrospective, observational, multicentric real-life study was realized including patients with SAA and CRSNP+ treated by omalizumab for 6 months...
April 1, 2019: Journal of Investigational Allergology & Clinical Immunology
https://read.qxmd.com/read/30741637/clinical-factors-associated-with-the-overuse-of-asthma-rescue-medication
#13
I Urrutia, J Delgado, J Domínguez-Ortega, E Mascarós, M Pérez, G Resler, V Plaza
BACKGROUND AND OBJECTIVE: Our aim was to evaluate the relationship between asthma clinical factors and use of relief medication. METHODS: This was an observational cross-sectional study conducted in Spain. The study recruited patients ≥ 12 years of age diagnosed with persistent asthma according to the GINA criteria and receiving maintenance treatment for at least 12 months. Use of relief medication was dichotomized: low use of rescue medication (LURM) (≤ twice/week) or high use of rescue medication (HURM) (≥ three times/week)...
February 11, 2019: Journal of Investigational Allergology & Clinical Immunology
https://read.qxmd.com/read/30741636/common-variable-immunodeficiency-epidemiology-pathogenesis-clinical-manifestations-diagnosis-classification-and-management
#14
REVIEW
R Yazdani, S Habibi, L Sharifi, G Azizi, H Abolhassani, P Olbrich, A Aghamohammadi
Common variable immunodeficiency (CVID) is a heterogeneous disorder characterized by hypogammaglobulinemia and increased susceptibility to recurrent bacterial infections. It is the most frequent symptomatic antibody deficiency with a wide variety of infectious and non-infectious complications. Numerous studies demonstrated that different immunological and genetic defects are involved in the pathogenesis of CVID. However, in most cases, the genetic background of the disease remains unidentified. This review aims to discuss different aspects of CVID including epidemiology, pathogenesis, symptoms, diagnosis, classifications and management of the disease...
February 11, 2019: Journal of Investigational Allergology & Clinical Immunology
https://read.qxmd.com/read/30741635/what-we-know-about-fish-allergy-by-the-end-of-the-decade
#15
REVIEW
E Kourani, F Corazza, O Michel, V Doyen
Fish allergy is one of the most common food allergies. It is usually considered to be immunoglobulin (Ig) E-mediated and correlated well with diagnostic tests such as prick tests and/or specific IgE. Recommended treatment is avoidance, generally extended to all fishes. However, new clinical presentations have been described, including non-IgE-mediated disease, mono-sensitization, and new syndromes that are sometimes associated with surprising cross-reactivity. Advances in molecular allergy have provided insights into new allergens and have increased our understanding of cross-reactivity...
February 11, 2019: Journal of Investigational Allergology & Clinical Immunology
https://read.qxmd.com/read/30676321/relevance-of-th2-markers-in-the-assessment-and-therapeutic-management-of-severe-allergic-asthma-a-real-life-perspective
#16
M Caminati, A Vianello, F Chieco Bianchi, G Festi, G Guarnieri, M R Marchi, C Micheletto, M Olivieri, S Tognella, M Guerriero, G Senna
BACKGROUND: Although blood eosinophils are currently recognized as the main clinical marker of Th2 inflammation, their relevance in identifying asthma severity is still matter of debate. METHODS: Our retrospective real-life study on severe asthmatics included in the NEONet Italian database, aimed at investigating the relevance of blood eosinophil count and FeNO in severe asthma clinical assessment and their role as a potential predictor of responsiveness to anti-IgE therapy...
January 24, 2019: Journal of Investigational Allergology & Clinical Immunology
https://read.qxmd.com/read/30676320/incidence-and-risk-factors-of-low-osmolar-iodinated-contrast-media-related-immediate-hypersensitivity-reactions-a-longitudinal-study-based-on-a-real-time-monitoring-system
#17
L Suh-Young, K Dong Yoon, K Ju-Young, Y Soon Ho, C Young-Hoon, L Whal, C Sang Heon, K Hye-Ryun
BACKGROUND: We investigated the incidence of immediate hypersensitivity reaction (HSR) focusing on the types of low osmolar contrast media (LOCM) and accumulated exposures to LOCM. METHODS: This cohort study included all consecutive patients who underwent LOCM-enhanced computed tomography scan from 2012 through 2014. Five LOCMs (iobitridol, iohexol, iomeprol, iopamidol, and iopromide) were used. All patients were monitored for adverse events and new symptoms and signs were recorded in the Contrast Safety Monitoring and Management System (CoSM2oS) in real-time...
January 24, 2019: Journal of Investigational Allergology & Clinical Immunology
https://read.qxmd.com/read/30676319/ige-mediated-sensitization-to-galactose-alpha-1-3-galactose-%C3%AE-gal-in-urticaria-and-anaphylaxis-in-spain-geographical-variations-and-risk-factors
#18
M B Mateo-Borrega, B Garcia, C Hernando Larramendi, J Azofra, E González-Mancebo, M I Alvarado, M D Alonso Díaz de Durana, R Núñez-Orjales, M C Diéguez, M Guilarte, A M Soriano-Galarraga, G Sosa, A Ferrer, A García-Moral, A M Beristain, J Bartra
BACKGROUND: The aims of this study were to investigate the prevalence of sIgE to galactose-alpha-1,3-galactose (α-gal) in individuals with acute urticaria or anaphylaxis from different geographical areas of Spain and to evaluate the relevance of demographics and lifestyle as risk factors for this immune response. METHODS: Participants were recruited from allergy departments at 14 Spanish hospitals. Patients aged 18 years or older presenting with urticaria or anaphylaxis were enrolled into one of two arms: cases and controls...
January 24, 2019: Journal of Investigational Allergology & Clinical Immunology
https://read.qxmd.com/read/30785115/hypothesized-epitope-localization-in-hypersensitivity-reactions-to-iodinated-contrast-media
#19
J Borras, D El-Qutob, R Lopez, E Enrique
No abstract text is available yet for this article.
February 2019: Journal of Investigational Allergology & Clinical Immunology
https://read.qxmd.com/read/30785114/severe-eosinophilic-allergic-asthma-responsive-to-mepolizumab-after-failure-of-2-consecutive-biologics
#20
M Sánchez-Jareño, P Barranco, D Romero, J Domínguez-Ortega, S Quirce
No abstract text is available yet for this article.
February 2019: Journal of Investigational Allergology & Clinical Immunology
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