Rui Ma, Xuemeng Zhou, Xiaohui Zhai, Chuyue Wang, Rong Hu, You Chen, Liyang Shi, Xing Fang, Yuan Liao, Lifeng Ma, Mengmeng Jiang, Junqing Wu, Renying Wang, Jiao Chen, Taiyuan Cao, Ge Du, Yingying Zhao, Weili Wu, Haide Chen, Shanshan Li, Qizhou Lian, Guoji Guo, Jian Xiao, Andrew P Hutchins, Ping Yuan
Highly aggressive gastric cancer (HAGC) is a gastric cancer characterized by bone marrow metastasis and disseminated intravascular coagulation (DIC). Information about the disease is limited. Here we employed single-cell RNA sequencing to investigate peripheral blood mononuclear cells (PBMCs), aiming to unravel the immune response of patients toward HAGC. PBMCs from seven HAGC patients, six normal advanced gastric cancer (NAGC) patients, and five healthy individuals were analysed by single-cell RNA sequencing...
February 6, 2024: Cell Proliferation