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Journals European Archives of Psychiatr...

European Archives of Psychiatry and Clinical Neuroscience

https://read.qxmd.com/read/38935216/harm-reduction-strategies-for-cannabis-related-problems-a-literature-review-and-typology
#21
JOURNAL ARTICLE
Jonathan Pratschke
Measures that seek to minimise the health and social consequences of substance use are an integral part of national drug strategies in many European countries. Against the backdrop of a high prevalence of cannabis use in the economically advanced countries, and increasing demand for treatment for cannabis-related problems, a range of harm reduction measures have been implemented by peers, statutory bodies and third-sector organisations. Based on a systematic review of the literature, the author describes these different forms of intervention, identifies innovative strategies and presents a simple typology that can be used when exploring existing measures or seeking to develop new policies...
June 27, 2024: European Archives of Psychiatry and Clinical Neuroscience
https://read.qxmd.com/read/38935215/effects-of-cognitive-behavioural-therapy-and-exposure-response-prevention-on-brain-activation-in-obsessive-compulsive-disorder-patients-systematic-review-and-meta-analysis
#22
JOURNAL ARTICLE
Callum Stephenson, Aaron Philipp-Muller, Elnaz Moghimi, Joseph Y Nashed, Douglas J Cook, Amirhossein Shirazi, Roumen Milev, Nazanin Alavi
Current psychotherapeutic treatments for OCD, while effective, have complex outcomes with mixed efficacy. Previous research has observed baseline brain activation patterns in OCD patients, elucidating some of the implications of this disorder. Observing the effects of evidence-based psychotherapeutics for OCD on brain activation (through MRI) may provide a more comprehensive outline of pathology. This systematic review and meta-analysis evaluated the effects of cognitive behavioural therapy (CBT) with exposure-response prevention (ERP) on brain activation in OCD patients...
June 27, 2024: European Archives of Psychiatry and Clinical Neuroscience
https://read.qxmd.com/read/38916765/attenuated-neural-activity-in-processing-decision-making-feedback-in-uncertain-conditions-in-patients-with-mild-cognitive-impairment
#23
JOURNAL ARTICLE
Ying Zhang, Mang Zhang, Luchun Wang, Yaonan Zheng, Huizi Li, Yuhan Xie, Xiaozhen Lv, Xin Yu, Huali Wang
The present study aimed to explore the potential neural correlates during feedback evaluation during decision-making under risk and ambiguity in MCI. Nineteen individuals with MCI and twenty age-matched HCs were enrolled. Decision-making performance under risk and ambiguity was examined with the modified game of dice task (GDT) and an Iowa gambling task (IGT). Using task-related EEG data, reward positivity (RewP) and feedback P3 (fb-P3) were used to characterize participants' motivation and allocation of cognitive resources...
June 25, 2024: European Archives of Psychiatry and Clinical Neuroscience
https://read.qxmd.com/read/38914855/disorganization-in-individuals-at-clinical-high-risk-for-psychosis-psychopathology-and-treatment-response
#24
JOURNAL ARTICLE
Arianna Biancalani, Michele Occhionero, Emanuela Leuci, Emanuela Quattrone, Silvia Azzali, Giuseppina Paulillo, Simona Pupo, Pietro Pellegrini, Marco Menchetti, Lorenzo Pelizza
Disorganization is a nuclear dimension of psychosis, especially in schizophrenia. Despite its relevant association with poor prognosis and negative outcomes, it is still under-investigated compared to positive and negative symptoms, in particular at the onset of illness. This study explored disorganization in youth at Clinical High Risk for Psychosis (CHR-P) over a 2-year period. A sample of 180 CHR-P participants (50% males; 51.1% with baseline second-generation antipsychotic medication) recruited within a specialized CHR-P service completed the Positive and Negative Syndrome Scale (PANSS) and the Global Assessment of Functioning (GAF) scale...
June 25, 2024: European Archives of Psychiatry and Clinical Neuroscience
https://read.qxmd.com/read/38914854/schizophrenia-and-risk-preference-a-bidirectional-two-sample-mendelian-randomization-study
#25
JOURNAL ARTICLE
Yixin Zhao, Weilong Guo, Jiansong Zhou, Xiaoping Wang
Increasing evidence shows that risk preference is associated with schizophrenia. However, the causality and direction of this association are not clear; Therefore, we used Mendelian randomization (MR) to examine the potential bidirectional relationship between risk preference and schizophrenia. Genome-wide association studies (GWAS) summary data on risk preference of 939,908 participants from the UK Biobank and 23andMe were used to identify general risk preference. Data from 320,404 subjects (76,755 cases and 243,649 controls) from The Psychiatric Genomics Consortium were used to identify schizophrenia...
June 25, 2024: European Archives of Psychiatry and Clinical Neuroscience
https://read.qxmd.com/read/38914853/diagnostic-value-of-regional-homogeneity-and-fractional-amplitude-of-low-frequency-fluctuations-in-the-classification-of-schizophrenia-and-bipolar-disorders
#26
JOURNAL ARTICLE
Giulia Cattarinussi, Fabio Di Camillo, David Antonio Grimaldi, Fabio Sambataro
Schizophrenia (SCZ) and bipolar disorders (BD) show significant neurobiological and clinical overlap. In this study, we wanted to identify indexes of intrinsic brain activity that could differentiate these disorders. We compared the diagnostic value of the fractional amplitude of low-frequency fluctuations (fALFF) and regional homogeneity (ReHo) estimated from resting-state functional magnetic resonance imaging in a support vector machine classification of 59 healthy controls (HC), 40 individuals with SCZ, and 43 individuals with BD type I...
June 25, 2024: European Archives of Psychiatry and Clinical Neuroscience
https://read.qxmd.com/read/38914852/headache-severity-in-patients-with-post-covid-19-condition-a-case-control-study
#27
JOURNAL ARTICLE
Mike Rueb, Michael Ruzicka, Gerardo Jesus Ibarra Fonseca, Elisabeth Valdinoci, Christopher Benesch, Anna Pernpruner, Max von Baum, Jan Remi, Tarek Jebrini, Florian Schöberl, Andreas Straube, Hans Christian Stubbe, Kristina Adorjan
Post COVID-19 conditions (PCC) present with a wide range of symptoms. Headache is one of the most frequently reported neurological symptoms by patients with PCC. We aimed to assess the prevalence of headache in patients with PCC who attended the Post-COVIDLMU outpatient department at LMU University Hospital in Munich. We hypothesized that headaches occur more frequently in patients with PCC than in the control group. Patients answered a questionnaire containing sociodemographic characteristics, their current symptoms, and prior psychiatric and somatic diagnoses, the WHO Quality of Life assessment (WHOQOL-BREF), 9-item Patient Health Questionnaire (PHQ-9), and the Fatigue Severity Scale (FSS)...
June 25, 2024: European Archives of Psychiatry and Clinical Neuroscience
https://read.qxmd.com/read/38914851/resting-state-functional-connectivity-correlates-of-brain-structural-aging-in-schizophrenia
#28
JOURNAL ARTICLE
Yana R Panikratova, Alexander S Tomyshev, Ekaterina G Abdullina, Georgiy I Rodionov, Andrey Yu Arkhipov, Denis V Tikhonov, Olga V Bozhko, Vasily G Kaleda, Valeria B Strelets, Irina S Lebedeva
A large body of research has shown that schizophrenia patients demonstrate increased brain structural aging. Although this process may be coupled with aberrant changes in intrinsic functional architecture of the brain, they remain understudied. We hypothesized that there are brain regions whose whole-brain functional connectivity at rest is differently associated with brain structural aging in schizophrenia patients compared to healthy controls. Eighty-four male schizophrenia patients and eighty-six male healthy controls underwent structural MRI and resting-state fMRI...
June 25, 2024: European Archives of Psychiatry and Clinical Neuroscience
https://read.qxmd.com/read/38914850/handedness-in-schizophrenia-and-affective-disorders-a-large-scale-cross-disorder-study
#29
JOURNAL ARTICLE
Annakarina Mundorf, Alexander Lischke, Jutta Peterburs, Nina Alexander, Linda M Bonnekoh, Katharina Brosch, Kira Flinkenflügel, Janik Goltermann, Tim Hahn, Andreas Jansen, Susanne Meinert, Igor Nenadić, Navid Nico Schürmeyer, Frederike Stein, Benjamin Straube, Katharina Thiel, Lea Teutenberg, Florian Thomas-Odenthal, Paula Usemann, Alexandra Winter, Udo Dannlowski, Tilo Kircher, Sebastian Ocklenburg
While most people are right-handed, a minority are left-handed or mixed-handed. It has been suggested that mental and developmental disorders are associated with increased prevalence of left-handedness and mixed-handedness. However, substantial heterogeneity exists across disorders, indicating that not all disorders are associated with a considerable shift away from right-handedness. Increased frequencies in left- and mixed-handedness have also been associated with more severe clinical symptoms, indicating that symptom severity rather than diagnosis explains the high prevalence of non-right-handedness in mental disorders...
June 25, 2024: European Archives of Psychiatry and Clinical Neuroscience
https://read.qxmd.com/read/38914849/crime-rates-in-wernicke-korsakoff-syndrome-and-alcohol-related-dementia-may-not-depend-solely-on-these-disorders
#30
LETTER
Josef Finsterer
No abstract text is available yet for this article.
June 25, 2024: European Archives of Psychiatry and Clinical Neuroscience
https://read.qxmd.com/read/38914848/neurobiological-similarities-and-clinical-differences-between-post-covid-and-depression-response-to-bonnet-and-kuhn-2024
#31
LETTER
Carla P Rus
No abstract text is available yet for this article.
June 25, 2024: European Archives of Psychiatry and Clinical Neuroscience
https://read.qxmd.com/read/38906983/correlation-of-altered-intrinsic-functional-connectivity-with-impaired-self-regulation-in-children-and-adolescents-with-adhd
#32
JOURNAL ARTICLE
Chia-Jui Tsai, Hsiang-Yuan Lin, Susan Shur-Fen Gau
BACKGROUND: Attention-deficit hyperactivity disorder (ADHD) has a high prevalence of co-occurring impaired self-regulation (dysregulation), exacerbating adverse outcomes. Neural correlates underlying impaired self-regulation in ADHD remain inconclusive. We aimed to investigate the impact of dysregulation on intrinsic functional connectivity (iFC) in children with ADHD and the correlation of iFC with dysregulation among children with ADHD relative to typically developing controls (TDC)...
June 22, 2024: European Archives of Psychiatry and Clinical Neuroscience
https://read.qxmd.com/read/38878077/genetics-of-suicide-ideation-a-role-for-inflammation-and-neuroplasticity
#33
JOURNAL ARTICLE
Fabrizio Turiaco, Fiammetta Iannuzzo, Antonio Bruno, Antonio Drago
Suicide is a leading cause of death worldwide. Suicide ideation (SI) is a known risk factor for suicide behaviour (SB). The current psychobiology and genetic predisposition to SI and SB are poorly defined. Despite convincing relevance of a genetic background for SI, there is no current implementable knowledge about the genetic makeup that identifies subjects at risk for it. One of the possible reasons for the absence of a clear-cut evidence is the polygenetic nature of SI along with the very large sample sizes that are needed to observe significant genetic association result...
June 15, 2024: European Archives of Psychiatry and Clinical Neuroscience
https://read.qxmd.com/read/38867084/treatment-demand-for-cannabis-use-problems-analyses-of-routine-data-from-30-european-countries
#34
JOURNAL ARTICLE
Jakob Manthey
Cannabis use and treatment demand has risen in the past decade. Previous analyses of treatment demand are limited by methodological constraints or are outdated. Cross-country differences and trends in cannabis treatment demand are described using data from the European Monitoring Centre for Drugs and Drug Addiction. Two novel indicators are employed: firstly, the cannabis-attributable treatment fraction (CATF) is obtained by dividing the number of treatment entrants for cannabis use problems by the number of treatment entrants for any substance use problem, accounting for possible changes in the reporting system...
June 12, 2024: European Archives of Psychiatry and Clinical Neuroscience
https://read.qxmd.com/read/38861240/interaction-of-childhood-trauma-with-bdnf-and-fkbp5-gene-polymorphisms-in-predicting-burnout-in-general-occupational-groups
#35
JOURNAL ARTICLE
Yuling Li, Haiying Jia, Xueqian Wei, Shiqian Zhen, Shu-Chang He, Xiang Yang Zhang
Both the BDNF gene rs6265 and the FKBP5 gene rs1360780 polymorphisms are independently associated with adult psychotic-like experiences, when exposed to high childhood abuse; however, it remains unclear whether the relationship between childhood abuse and burnout is moderated by these two single nucleotide polymorphisms (SNPs). Furthermore, there is an interaction between glucocorticoid receptor transcriptional activity and BDNF signaling. Therefore, we investigated the interaction of these two SNPs with childhood trauma in predicting burnout...
June 11, 2024: European Archives of Psychiatry and Clinical Neuroscience
https://read.qxmd.com/read/38861239/characterization-of-cannabis-users-and-products-and-the-experience-of-negative-mental-emotions-following-cannabis-use
#36
JOURNAL ARTICLE
Nir Treves, Noa Yakirevich-Amir, Wiessam Abu Ahmad, Omer Bonne, Elyad Davidson, Keenan Keeling, Branden Hall, Tyler Dautrich, Ilan Matok
There is a potential link between cannabis and mental disorders. Cannabis exposure involves in many cases negative mental emotions, which are unpleasant sensations or thoughts. Whereas mild cases of negative mental emotions inflict patient's quality of life, more severe cases lead to therapy discontinuations, or even hospitalizations and death. This study characterizes cannabis users who experienced negative mental emotions after cannabis exposure. The Releaf App database was utilized to evaluate the association between personal and cannabis use characteristics on reporting a negative mental emotion during cannabis exposure...
June 11, 2024: European Archives of Psychiatry and Clinical Neuroscience
https://read.qxmd.com/read/38851655/naturalistic-comparison-of-clomethiazole-and-diazepam-treatment-in-alcohol-withdrawal-effects-on-oxidative-stress-inflammatory-cytokines-and-hepatic-biomarkers
#37
JOURNAL ARTICLE
David Strischewski, Amira Kalmar, Paul C Guest, Henrik Dobrowolny, Gabriela Meyer-Lotz, Conrad J Schiffner, Wolfgang Jordan, Ulf J Müller, Katrin Borucki, Michael Böttcher, Borna Relja, Johann Steiner
Ethanol is metabolized by alcohol dehydrogenase to acetaldehyde and induces cytochrome P450 2E1 (CYP2E1), which generates reactive oxygen species that cause inflammatory liver damage. Clomethiazole, a drug approved for alcohol withdrawal treatment (AWT) in some European countries, inhibits CYP2E1. We hypothesized that clomethiazole would lead to a faster reduction in oxidative stress, inflammatory cytokines, and liver enzymes compared to diazepam treatment. We analysed respective biomarkers in 50 patients undergoing AWT and 25 healthy individuals but found no statistical difference between the two medication groups over 3-5 days...
June 8, 2024: European Archives of Psychiatry and Clinical Neuroscience
https://read.qxmd.com/read/38839710/how-to-assess-response
#38
LETTER
Steffen Zitzmann, Christoph Lindner
No abstract text is available yet for this article.
June 5, 2024: European Archives of Psychiatry and Clinical Neuroscience
https://read.qxmd.com/read/38829442/post-covid-depression-and-anxiety-are-multicausal-and-not-necessarily-due-to-sars-cov-2-infection
#39
LETTER
Josef Finsterer
No abstract text is available yet for this article.
June 3, 2024: European Archives of Psychiatry and Clinical Neuroscience
https://read.qxmd.com/read/38824476/associations-of-tau-a%C3%AE-and-brain-volume-of-the-papez-circuit-with-cognition-in-alzheimer-s-disease
#40
JOURNAL ARTICLE
Yuxue Feng, Azka Laraib, Xiuqi Lin, Qin Li, Jiehong Zhan, Xiaofeng Li
This study aimed to investigate the cross-sectional associations between regional Alzheimer's disease (AD) biomarkers, including tau, β-amyloid (Aβ), and brain volume, within the Papez circuit, and neuropsychological functioning across the preclinical and clinical spectrum of AD. We utilized data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database, including 251 Aβ-positive participants. Participants were categorized into three groups based on the Clinical Dementia Rating (CDR): 73 individuals with preclinical AD (CDR = 0), 114 with prodromal AD (CDR = 0...
June 2, 2024: European Archives of Psychiatry and Clinical Neuroscience
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