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Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging

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https://read.qxmd.com/read/30771278/ct-attenuation-of-acute-subdural-hematomas-in-patients-with-anemia
#1
Lindsay Duy, Arwa Badeeb, Walter Duy, Eman Alqahtani, Walter Champion, Dae Hee Kim, Dann Martin, Vartan Vartanians, Phillip Coffin, Juan E Small
BACKGROUND AND PURPOSE: Isodense and hypodense acute subdural hematomas have been reported in the literature in anemic patients. The purpose of this study is to see if there is a statistically significant difference between the Hounsfield unit measurements of acute subdural hematomas in anemic and nonanemic patients. METHODS: A total of 109 patients were analyzed. We measured the most hyperdense component of the subdural hematoma and compared these measurements for both anemic and nonanemic patients...
February 16, 2019: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://read.qxmd.com/read/30761654/vessel-wall-mri-added-to-mr-angiography-in-the-evaluation-of-suspected-vasculopathies
#2
Jae W Song, Emmanuel C Obusez, Scott B Raymond, Samuel D Rafla, Pamela W Schaefer, Javier M Romero
BACKGROUND AND PURPOSE: We hypothesized that vessel wall MR imaging (VWI) with 3D-time-of-flight magnetic resonance imaging (3D-TOF-MRA) together increases the ability to detect abnormal intracranial vessel segments compared to 3D-TOF-MRA alone. METHODS: Ninety-three consecutive subjects with a clinical history of suspected vasculopathy imaged with both VWI and 3D-TOF-MRAs were retrospectively reviewed. The 3D-TOF-MRAs were reviewed by two independent neuroradiologists classifying arterial segments as normal or abnormal based on caliber changes...
February 13, 2019: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://read.qxmd.com/read/30748053/cerebrovascular-reactivity-impairment-in-preclinical-alzheimer-s-disease
#3
Mohammed Alwatban, Daniel L Murman, Greg Bashford
BACKGROUND AND PURPOSE: A substantial overlap exists between declines in cerebral vasoreactivity (CVR) and symptomatic Alzheimer's disease (AD). CVR can be quantified using transcranial Doppler (TCD) measurement of cerebral blood flow velocities (CBFV) in the middle cerebral artery (MCA) with CO2 as a vasodilatory stimulus. The breath-hold acceleration index (BHAI) is a new, more reliable measure of CVR developed recently in our laboratory. Our primary goal is to explore the possibility of using TCD for asymptomatic AD screening...
February 12, 2019: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://read.qxmd.com/read/30748043/myelinating-proteins-in-ms-are-linked-to-volumetric-brain-mri-changes
#4
Staley A Brod, John A Lincoln, Flavia Nelson
BACKGROUND AND PURPOSE: There is evidence of a relationship between promyelinating proteins and clinical multiple sclerosis (MS) activity during clinical relapse or recovery from clinical relapses. We examined the linkage between promyelinating biomarkers and volumetric changes in MS subjects during serial magnetic resonance imaging (MRI). METHODS: We enrolled 13 MS subjects with active brain MRI scans not on disease modifying therapies. Subjects underwent baseline MRI, serum, and cerebrospinal fluid (CSF) sampling...
February 12, 2019: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://read.qxmd.com/read/30714259/ultrasonography-monitoring-of-optic-nerve-sheath-diameter-and-retinal-vessels-in-patients-with-cerebral-hemorrhage
#5
Andrea Naldi, Emanuele Pivetta, Lorenzo Coppo, Roberto Cantello, Cristoforo Comi, Alessandro Stecco, Paolo Cerrato, Martin Lesmeister, Piergiorgio Lochner
BACKGROUND AND PURPOSE: Evaluation of the diagnostic accuracy of optic nerve sheath diameter (ONSD) and Doppler indices of central retinal arteries and veins for the detection of increased intracranial pressure (ICP) in intracerebral hemorrhage (ICH) and of the usefulness of a second assessment of these variables in the monitoring of ICH. METHODS: A total of 46 acute ICH patients with (group 1, n = 25) and without (group 2, n = 21) clinical and radiological computed tomography signs of raised ICP and 40 healthy controls were recruited...
February 3, 2019: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://read.qxmd.com/read/30714246/adaptive-identification-of-cortical-and-subcortical-imaging-markers-of-early-life-stress-and-posttraumatic-stress-disorder
#6
Lauren E Salminen, Rajendra A Morey, Brandalyn C Riedel, Neda Jahanshad, Emily L Dennis, Paul M Thompson
BACKGROUND AND PURPOSE: Posttraumatic stress disorder (PTSD) is a heterogeneous condition associated with a range of brain imaging abnormalities. Early life stress (ELS) contributes to this heterogeneity, but we do not know how a history of ELS influences traditionally defined brain signatures of PTSD. Here, we used a novel machine learning method - evolving partitions to improve classification (EPIC) - to identify shared and unique structural neuroimaging markers of ELS and PTSD in 97 combat-exposed military veterans...
February 3, 2019: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://read.qxmd.com/read/30714241/18f-florbetaben-pet-ct-to-assess-alzheimer-s-disease-a-new-analysis-method-for-regional-amyloid-quantification
#7
Pierpaolo Alongi, Davide Stefano Sardina, Rosalia Coppola, Salvatore Scalisi, Valentina Puglisi, Annachiara Arnone, Giorgio Di Raimondo, Elisabetta Munerati, Valerio Alaimo, Federico Midiri, Giorgio Russo, Alessandro Stefano, Rosalba Giugno, Tommaso Piccoli, Massimo Midiri, Luigi M E Grimaldi
BACKGROUND AND PURPOSE: While AD can be definitively confirmed by postmortem histopathologic examination, in vivo imaging may improve the clinician's ability to identify AD at the earliest stage. The aim of the study was to test the performance of amyloid PET using new processing imaging algorithm for more precise diagnosis of AD. METHODS: Amyloid PET results using a new processing imaging algorithm (MRI-Less and AAL Atlas) were correlated with clinical, cognitive status, CSF analysis, and other imaging...
February 3, 2019: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://read.qxmd.com/read/30702779/the-role-of-transcranial-doppler-monitoring-in-patients-with-multi-territory-acute-embolic-strokes-a-review
#8
REVIEW
Odysseas Kargiotis, Klearchos Psychogios, Apostolos Safouris, Georgios Magoufis, Paschalis D Zervas, Eleftherios Stamboulis, Georgios Tsivgoulis
Acute multi-territory, embolic cerebral infarctions are often associated with serious underlying clinical conditions including the presence of highly "active" emboligenic sources causing that in turn may result in high early recurrence rates. Prompt diagnosis, risk stratification, and treatment are substantial for the prevention of subsequent embolization that would result in further clinical deterioration. Among other clinical investigations, transcranial Doppler (TCD) monitoring is highly efficacious for the detection of microembolic signals (MES) that correspond to microthrombi entering the intracranial circulation...
January 31, 2019: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://read.qxmd.com/read/30702182/variability-of-resting-state-functional-mri-graph-theory-metrics-across-3t-platforms
#9
Ranliang Hu, Deqiang Qiu, Ying Guo, Yujie Zhao, Christopher Leatherday, Junjie Wu, Jason W Allen
BACKGROUND AND PURPOSE: Graph theory analysis of brain connectivity data is a promising tool for studying the function of the healthy and diseased brain. The consistency of resting-state functional MRI (rsfMRI) connectivity measures across multiple scanner types is an important factor in designing multi-institutional research studies and has important implications for the potential use of this technique in a heterogeneous clinical setting. We sought to quantitatively study the interscanner variability of rsfMRI graph theory metrics obtained from healthy volunteers scanned on three different scanner platforms...
January 31, 2019: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://read.qxmd.com/read/30681223/a-relative-noncontrast-ct-map-to-detect-early-ischemic-changes-in-acute-stroke
#10
Aditya Srivatsan, Søren Christensen, Maarten G Lansberg
BACKGROUND AND PURPOSE: Early ischemic changes on noncontrast computed tomography (NCCT) are often subtle. We developed a novel postprocessing technique that aids in detecting such changes. METHODS: NCCT maps were generated that display the relative density difference between corresponding voxels in contralateral hemispheres (ratio maps of the NCCT [rNCCT]). Voxels with a relative density difference below .95 were designated as infarct. We pilot tested the rNCCT for infarct segmentation on 6 consecutive subjects enrolled in the CT Perfusion to predict Response in Ischemic Stroke Project (CRISP) study and applied the inclusion criteria of an adequate quality NCCT and successful endovascular reperfusion This seems too complex for the abstract, specially since all the abbreviations are now spelled out...
January 25, 2019: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://read.qxmd.com/read/30663173/the-role-of-ct-perfusion-in-defining-the-clinically-relevant-core-infarction-to-guide-thrombectomy-selection-in-patients-with-acute-stroke
#11
Hussam Shaker, Muhib Khan, Todd Mulderink, Tracy J Koehler, Raymond Scurek, Tricia Tubergen, Laurel Packard, Justin Singer, Paul Mazaris, Jiangyong Min, Nabil Wees, Nadeem Khan, Tamer Abdelhak
BACKGROUND AND PURPOSE: Infarct core assessment on presentation is important to evaluate salvageable tissue to select patients for thrombectomy. Our study aims to evaluate the correlation between infarct core volume measured by computed tomography (CT) perfusion (CTP) and magnetic resonance diffusion-weighted imaging (MR-DWI) in patients with acute large-vessel occlusion. METHODS: We studied patients who underwent CTP on presentation to the emergency department for stroke symptoms...
January 20, 2019: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://read.qxmd.com/read/30648771/functional-mri-task-comparison-for-language-mapping-in-neurosurgical-patients
#12
Prashin Unadkat, Luca Fumagalli, Laura Rigolo, Mark G Vangel, Geoffrey S Young, Raymond Huang, Srinivasan Mukundan, Alexandra Golby, Yanmei Tie
BACKGROUND AND PURPOSE: Language task-based functional MRI (fMRI) is increasingly used for presurgical planning in patients with brain lesions. Different paradigms elicit activations of different components of the language network. The aim of this study is to optimize fMRI clinical usage by comparing the effectiveness of three language tasks for language lateralization and localization in a large group of patients with brain lesions. METHODS: We analyzed fMRI data from a sequential retrospective cohort of 51 patients with brain lesions who underwent presurgical fMRI language mapping...
January 16, 2019: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://read.qxmd.com/read/30648770/accuracy-of-at-risk-tissue-predictions-using-ct-perfusion-in-acute-large-vessel-occlusions
#13
Songmi Lee, Albert J Yoo, Henk A Marquering, Olvert A Berkhemer, Charles B Majoie, Diederik W J Dippel, Sunil A Sheth
BACKGROUND AND PURPOSE: The validity of CT perfusion (CTP) predictions of expected infarction volume ("at risk" tissue) without rapid recanalization remains poorly characterized. METHODS: From the MR CLEAN trial, we included patients who underwent CTP without successful recanalization. "At risk" volume was defined as Tmax > 6 seconds and ischemic core as relative CBF < 30 (Olea Sphere). Coprimary outcomes were follow-up infarct volume (FIV) on CT at 1-5 days and 90-day mRS...
January 16, 2019: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://read.qxmd.com/read/30644143/mri-features-associated-with-tert-promoter-mutation-status-in-glioblastoma
#14
Jana Ivanidze, Mark Lum, David Pisapia, Rajiv Magge, Rohan Ramakrishna, Ilhami Kovanlikaya, Howard A Fine, Gloria C Chiang
BACKGROUND AND PURPOSE: Telomerase reverse transcriptase (TERT) promoter mutations are associated with worse prognosis in glioblastoma. The purpose of this study was to evaluate whether TERT mutation status was associated with specific morphologic and quantitative imaging features. METHODS: Twenty-nine patients with isocitrate dehydrogenase 1/2-wildtype glioblastoma (13 TERT-wildtype, 16 TERT-mutated), who underwent preoperative magnetic resonance (MR) imaging were included in this retrospective study...
January 15, 2019: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://read.qxmd.com/read/30640412/semiautomated-assessment-of-the-anterior-cingulate-cortex-in-alzheimer-s-disease
#15
Flora Jung, Samaneh Kazemifar, Robert Bartha, Nagalingam Rajakumar
BACKGROUND AND PURPOSE: The anterior cingulate cortex (ACC) is involved in several cognitive processes including executive function. Degenerative changes of ACC are consistently seen in Alzheimer's disease (AD). However, volumetric changes specific to the ACC in AD are not clear because of the difficulty in segmenting this region. The objectives of the current study were to develop a precise and high-throughput approach for measuring ACC volumes and to correlate the relationship between ACC volume and cognitive function in AD...
January 14, 2019: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://read.qxmd.com/read/30623511/cytotoxic-edema-in-pediatric-abusive-head-trauma-adopting-a-common-nomenclature
#16
LETTER
Ligia Batista Silverman, Daniel M Lindberg, Brent R O'Neill
No abstract text is available yet for this article.
January 8, 2019: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://read.qxmd.com/read/30600871/neurosonography-after-mechanical-thrombectomy-for-acute-stroke-treatment
#17
Benno Ikenberg, Benjamin Scharsich, Sebastian Mönch, Silke Wunderlich, Kathleen Bernkopf, Tobias Boeckh-Behrens, Benjamin Friedrich, Christian Maegerlein, Holger Poppert, Christian L Seifert
BACKGROUND AND PURPOSE: Mechanical thrombectomy has been shown to be effective for acute stroke treatment, but lesions of cerebral vessels can develop thereafter. Such lesions of recanalized vessels and altered cerebral hemodynamics after mechanical thrombectomy are poorly investigated. In particular for neurosonography, data are sparse. We aimed to describe hemodynamic changes and incidence of de-novo stenosis after mechanical thrombectomy with neurosonography. METHODS: Retrospective analysis of patients after successful mechanical thrombectomy for acute stroke therapy who received one neurosonography at baseline and during follow up...
January 2, 2019: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://read.qxmd.com/read/30582252/gray-vs-white-matter-segmentation-of-the-conus-medullaris-reliability-and-variability-in-healthy-volunteers
#18
Marios C Yiannakas, Martina D Liechti, Nuttakarn Budtarad, Patrick Cullinane, Xixi Yang, Ahmed T Toosy, Jalesh N Panicker, Claudia A M Gandini Wheeler-Kingshott
BACKGROUND AND PURPOSE: Magnetic resonance imaging (MRI)-derived spinal cord (SC) gray and white matter (GM/WM) volume are useful indirect measures of atrophy and neurodegeneration over time, typically obtained in the upper SC. Neuropathological evidence suggests that in certain neurological conditions, early degeneration may occur as low as the sacral SC. In this study, the feasibility of GM/WM segmentation of the conus medullaris (CM) was assessed in vivo. METHODS: Twenty-three healthy volunteers (11 female, mean age 47 years) underwent high-resolution 3T MRI of the CM using a 3-dimensional fast field echo sequence...
December 24, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://read.qxmd.com/read/30582247/ultrasound-derived-nerve-cross-sectional-area-in-extremes-of-height-and-weight
#19
Emilie H Lothet, Timothy J Bishop, Francis O Walker, Michael S Cartwright
BACKGROUND AND PURPOSE: There is a lack of consensus in the literature as to which body habitus parameter most influences nerve cross-sectional area (CSA). This study was specifically designed to determine if height or weight is more influential. METHODS: Fifteen young healthy participants, 8 extremely tall and 7 heavy, with no peripheral nerve symptoms were recruited. The tall cohort consisted of males who were 74 inches or taller and females who were 68 inches or taller...
December 24, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
https://read.qxmd.com/read/30537408/brain-mri-lesions-are-related-to-bowel-incontinence-in-multiple-sclerosis
#20
Kilian Fröhlich, Ralf A Linker, Tobias Engelhorn, Arnd Dörfler, De-Hyung Lee, Konstantin Huhn, Stefan Schwab, Max J Hilz, Frank Seifert, Klemens Winder
BACKGROUND AND PURPOSE: Bowel incontinence in multiple sclerosis might be associated with specific lesion sites. This study intended to determine associations between bowel incontinence and cerebral multiple sclerosis lesions using a voxel-wise lesion symptom mapping analysis. METHODS: We conducted a retrospective study of multiple sclerosis patients with self-reported bowel incontinence and matched controls. Lesions were manually outlined on T2-weighted MRI scans and transformed into stereotaxic space...
December 11, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
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