Yunkyoung Oh, Youn-Joo Jung, Purja Sujata, Minji Kim, Dong Keon Yon, Seung Won Lee, Kyuyeon Cho, Ai Koyanagi, Zhaoli Dai, Eunyoung Kim, Jae Il Shin, Lee Smith
OBJECTIVES: Spin, defined as the misrepresentation of the results of a study, could negate the validity of scientific findings. We aimed to evaluate spin in early published RCTs on pharmacotherapy for COVID-19 with nonsignificant primary outcomes, explore the manifestation of spin, and identify the factors affecting spin in COVID-19 RCTs. METHODS: A systematic review was performed through a search of RCTs from PubMed/Medline, National Institutes of Health, EMBASE, Cochrane, and Web of Science...
October 11, 2023: Accountability in Research