Yuna Kim, Junbo Sim, Kyungeun Jeon, Dehun Ryu, Youngeun Ji, Youngseok Kim, Junoh Kim, Suwon Jeon, Deokhoon Park, Eunsun Jung
BACKGROUND: Continuous exposure of the skin to ultraviolet B (UVB) rays can cause inflammation and photodamage. In previous studies, we observed that the upregulation of nc886, a noncoding RNA (ncRNA), can alleviate UVB-induced inflammation through suppression of the protein kinase RNA (PKR) pathway. We aim to investigate the effect of fermented black ginseng extract (FBGE), which has been shown to increase the expression of nc886, on UVB-induced inflammation in keratinocytes. METHODS: To confirm the cytotoxicity of FBGE, MTT assay was performed, and no significant cytotoxicity was found on human keratinocytes...
November 14, 2023: Photodermatology, Photoimmunology & Photomedicine