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JOURNAL ARTICLE
Nazarul Hassan Jafry, Nausheen Butt, Muhammed Mubarak, Syed Fazal Akhtar
Acute kidney injury (AKI) is not uncommon during pregnancy but anti-glomerular basement membrane (anti-GBM) disease as a cause is rare. We report a case of a 30-year-old female, gravida 3, para 2, referred for impaired kidney function found during the investigation of anemia, around the 27th week of gestation. Kidney biopsy revealed crescentic glomerulonephritis secondary to anti-GBM antibodies. Aggressive therapy with intravenous pulse steroids, pulse cyclophosphamide, and plasma exchange was started...
September 28, 2024: Journal of Nephrology
#22
JOURNAL ARTICLE
Imre Demirhan, Mathijs van Oevelen, Zeinab Skalli, Carlijn G N Voorend, Simon P Mooijaart, Yvette Meuleman, Marianne C Verhaar, Willem Jan W Bos, Marjolijn van Buren, Alferso C Abrahams
BACKGROUND: Impaired cognition, poor health-related quality of life (HRQoL) and depressive symptoms are common in older patients with kidney failure. Understanding what influences HRQoL is important, as older patients regard HRQoL as a health priority. This study examines whether cognitive functioning is associated with HRQoL and whether depressive symptoms mediate this effect in older patients with kidney failure. METHODS: Outpatients aged ≥ 65 years from 35 Dutch and Belgian hospitals with eGFR 20-10 mL/min/1...
September 26, 2024: Journal of Nephrology
#23
EDITORIAL
Ekamol Tantisattamo, Umberto Maggiore
No abstract text is available yet for this article.
September 26, 2024: Journal of Nephrology
#24
JOURNAL ARTICLE
Ilyas Ozturk, Ozkan Gungor, Savas Ozturk, Refik Olmaz, Ayse Jini Gunes Keskin, Ismail Kocyigit, Murat Hayri Sipahioglu, Fatih Dede, Sena Ulu, Kenan Turgutalp, Dilek Torun, Tuncay Sahutoglu, Fatih Mehmet Erdur, Orcun Altunoren, Ramazan Danis, Gursel Yildiz, Ali Gurel, Mehmet Horoz, Mehmet Kucuksu, Suleyman Karakose, Tolga Yildirim, Mehmet Riza Altiparmak, Mehmet Deniz Ayli, Murat Tugcu, Zehra Eren, Eray Eroglu, Yasemin Coskun Yavuz, Esra Akcali, Dede Sit, Mehmet Polat, Saliha Yildirim, Selma Alagoz, Sibel Gokcay Bek, Irem Pembegul, Tahsin Karaaslan, Mustafa Keles, Funda Sari, Ustun Yilmaz, Numan Gorgulu, Gulizar Sahin, Zeki Aydin, Serap Yadigar, Ozkan Ulutas, Nedim Yilmaz Selcuk, Yavuz Ayar, Didem Turgut, Ozgur Akin Oto, Mehmet Koc, Alaattin Yıldız, Serhan Tuglular, Mehmet Sukru Sever
BACKGROUND: Each year, millions face natural disasters, encountering mass fatalities and severe medical issues such as crush injuries and crush syndrome. Crush syndrome, marked by acute kidney injury (AKI) and hyperkalemia, correlates with mortality. This study focuses on presenting epidemiological data on kidney disease resulting from the February 6, 2023 earthquakes centered in Kahramanmaras. METHODS: This retrospective analysis included patients diagnosed with crush syndrome after the 2023 Kahramanmaras earthquakes, treated in regional hospitals or referred elsewhere in Turkey...
September 25, 2024: Journal of Nephrology
#25
LETTER
Flavia Maria Borges Vigil, Pedro Alves Soares Vaz de Castro, Bruno Wilnes, Arthur Aguiar Amaral, Beatriz Castello-Branco, Ana Cristina Simões E Silva
No abstract text is available yet for this article.
September 24, 2024: Journal of Nephrology
#26
REVIEW
Mehmet Kanbay, Berk Mizrak, Sidar Copur, Carlo Basile
Chronic kidney disease (CKD) is among the leading causes of morbidity and mortality as it affects more than 10% of the global adult population. Cognitive impairment has a positive correlation with the stage of CKD. It has been recorded in more than half of CKD patients undergoing kidney replacement therapy. The assessment of cognitive function in dialysis patients presents challenges due to various patient limitations. Such a common debilitating comorbidity of CKD has no approved treatment option, highlighting the importance of preventive measures and screening modalities...
September 21, 2024: Journal of Nephrology
#27
LETTER
Federica Neve Vigotti
No abstract text is available yet for this article.
September 20, 2024: Journal of Nephrology
#28
REVIEW
Maulana Antiyan Empitu, Pranindya Rinastiti, Ika Nindya Kadariswantiningsih
Despite advances in diabetes management, there is an urgent need for novel therapeutic strategies since the current treatments remain insufficient in halting the progression of diabetic nephropathy-diabetic kidney disease (DN-DKD). This review is mainly addressed on the pivotal role of endothelin-1 in the pathophysiology of DN, with a specific focus on its effects on podocytes and the glomerular filtration barrier. Endothelin-1 promotes mesangial cell proliferation, sclerosis, and direct podocyte injury via the activation of endothelin type A and B receptors, that drive the progression of glomerulosclerosis in DN-DKD...
September 20, 2024: Journal of Nephrology
#29
JOURNAL ARTICLE
Wei Zhang, Xiaochun Zhou, Weikai Wang, Li Wang, Chuan Zhang, Jianqin Wang
BACKGROUND: Congenital anomalies of the kidney and urinary tract (CAKUT) are among the most common causes of kidney diseases in children. Previous studies on CAKUT etiologies have been predominantly focused on non-modifiable genetic risk factors. The existing nongenetic studies are limited by lack of comprehensive investigation of potentially modifiable risk factors and the inability to distinguish among various phenotypes of CAKUT. Therefore, this study aimed to comprehensively evaluate both maternal and fetal risk factors of CAKUT, sorted by disease phenotype...
September 20, 2024: Journal of Nephrology
#30
JOURNAL ARTICLE
Martha Spiteri, Sarah Camilleri, Nancy Formosa, Daniela Grima, Edith Said, Valerie Said Conti
No abstract text is available yet for this article.
September 19, 2024: Journal of Nephrology
#31
JOURNAL ARTICLE
Rashmi Joshi, Carmine Secondulfo, Alessandro Caputo, Pio Zeppa, Candida Iacuzzo, Luca Apicella, Margherita Borriello, Giancarlo Bilancio, Davide Viggiano
BACKGROUND: Kidney transplant recipients (KTRs) rely on immunosuppressants like mycophenolate to prevent organ rejection. However, mycophenolate often causes intestinal symptoms and inflammation in various organs, including the skin and the colon. While KTRs have an increased risk for skin cancer, the risk of colorectal cancer is not increased. Elucidating the histological alterations in the colon of KTRs and comparing these changes with known skin alterations would help understand how immunosuppressants influence cancer development and progression...
September 18, 2024: Journal of Nephrology
#32
JOURNAL ARTICLE
Gareth Murcutt, Rosie Hillson, Cate Goodlad, Andrew Davenport
BACKGROUND: Haemodialysis treatments generate greenhouse gas (GHG) emissions mainly as a result of the equipment, consumables and pharmaceuticals required. An internal audit demonstrated a 33% wastage of acid concentrate when using individual 5.0 L containers at a 1:44 dilution ratio. We therefore investigated whether changing the delivery system for acid concentrate would reduce wastage and any associated greenhouse gas emissions. METHODS: We calculated the difference for a 30-bed dialysis unit between receiving acid concentrate in single-use 5...
September 18, 2024: Journal of Nephrology
#33
JOURNAL ARTICLE
Takahide Iwasaki, Akihiro Kuma, Makoto Yoshida, Masataka Ikeda, Takahiro Kuragano
No abstract text is available yet for this article.
September 17, 2024: Journal of Nephrology
#34
REVIEW
Ka Chun Leung, Stephen Mahony, Edwina A Brown, Richard W Corbett
BACKGROUND: Intraperitoneal pressure measurement offers therapeutic and prognostic benefits in predicting leak risks and gastrointestinal symptoms in Peritoneal Dialysis (PD) patients. This systematic review aims to evaluate the prognostic utility of intraperitoneal pressure measurements and different estimated intraperitoneal pressure equations in predicting the risk of non-infectious complications in PD patients. METHODS: Databases including MEDLINE, EMBASE and Cochrane were searched up to July 2023...
September 16, 2024: Journal of Nephrology
#35
REVIEW
Anjay P Shah, William Snead, Anshul Daga, Rayon Uddin, Esra Adiyeke, Tyler J Loftus, Azra Bihorac, Yuanfang Ren, Tezcan Ozrazgat-Baslanti
BACKGROUND: Acute kidney injury (AKI) is a multifaceted disease characterized by diverse clinical presentations and mechanisms. Advances in artificial intelligence have propelled the identification of AKI subphenotypes, enhancing our capacity to customize treatments and predict disease trajectories. METHODS: We conducted a systematic review of the literature from 2017 to 2022, focusing on studies that utilized machine learning techniques to identify AKI subphenotypes in adult patients...
September 16, 2024: Journal of Nephrology
#36
JOURNAL ARTICLE
Zi Wang, Xiaoying Ma, Shaomei Li, Huaying Pei, Jinghong Zhao, Ying Zhang, Zibo Xiong, Yumei Liao, Ying Li, Qiongzhen Lin, Wenbo Hu, Yulin Li, Zhaoxia Zheng, Liping Duan, Gang Fu, Shanshan Guo, Beiru Zhang, Rui Yu, Li Hao, Guiling Liu, Zhanzheng Zhao, Jing Xiao, Yulan Shen, Yong Zhang, Xuanyi Du, Tianrong Ji, Caili Wang, Lirong Deng, Yingli Yue, Shanshan Chen, Zhigang Ma, Yingping Li, Li Zuo, Huiping Zhao, Xianchao Zhang, Xuejian Wang, Yirong Liu, Xinying Gao, Xiaoli Chen, Hongyi Li, Shutong Du, Cui Zhao, Zhonggao Xu, Li Zhang, Hongyu Chen, Li Li, Lihua Wang, Yan Yan, Yingchun Ma, Yuanyuan Wei, Jingwei Zhou, Yan Li, Fuyun Sun, Jie Dong
BACKGROUND: Hypokalemia has been associated with an increased risk of peritoneal dialysis (PD)-associated peritonitis. However, hypokalemia is commonly associated with malnutrition, inflammation, and severe coexisting comorbidities, which thus are suspected of being potential confounders. This study was aimed at testing whether hypokalemia was independently associated with the occurrence and prognosis of PD-associated peritonitis. METHODS: A national-level dataset from the Peritoneal Dialysis Telemedicine-assisted Platform Cohort (PDTAP) Study was used to explore the independent association of serum potassium with PD-associated peritonitis...
September 15, 2024: Journal of Nephrology
#37
JOURNAL ARTICLE
Yifei Wu, Xiao Xu, Quan Wenxiang, Jie Dong
BACKGROUND: Carrying out dialysis at home brings non-medical factors, including social support, or caretaker relationship, and internal features relevant to personality into the forefront. In this study, we aimed to explore the relationship between coping strategies of patients undergoing continuous ambulatory peritoneal dialysis (CAPD) and health outcomes. METHODS: Our post-hoc analysis was based on one previous randomized controlled trial that enrolled 150 incident patients who started CAPD from December 2010 to June 2016...
September 14, 2024: Journal of Nephrology
#38
REVIEW
Giulia Chimenti, Anna Magli, Giulia Spanu, Giulia Santagati, Antioco Fois, Linda Njandjo, Cristina Adriana Popa, Massimo Torreggiani, Giorgina Barbara Piccoli
Contraception, pregnancy and fertility are seldom discussed with women receiving dialysis and the medical staff of dialysis centres. Since the majority of women on dialysis are past childbearing age, these themes are not always given proper consideration and this category of patients may be missing important information. Young women of childbearing age who are on dialysis frequently experience sexual dysfunction and hormonal disorders of the hypothalamic-pituitary-gonadal axis. In addition, dialysis often has a relevant psychological impact and affects the person's social role...
September 13, 2024: Journal of Nephrology
#39
JOURNAL ARTICLE
Yuri Battaglia, Federica Baciga, Francesca Bulighin, Maria Amicone, Giovanni Mosconi, Alda Storari, Rachele Brugnano, Marco Pozzato, Daria Motta, Claudia D'alessandro, Claudia Torino, Francesca Mallamaci, Adamasco Cupisti, Filippo Aucella, Alessandro Capitanini
The Italian Society of Nephrology has tasked its Working Group on Physical Exercise with developing a consensus statement document on physical activity and exercise in patients with chronic kidney disease (CKD). This paper consists of 16 points that were discussed, and approved using the mini-Delphi method by 15 members of the working group. Each statement is based on a comprehensive review of the literature, clinical experience, and expert opinions. Overall, the statements affirm that regular physical activity and exercise training offer numerous benefits to CKD patients, including improved physical function, enhanced cardiometabolic and neuromuscular function, cognitive benefits, and an overall improvement in quality of life...
September 13, 2024: Journal of Nephrology
#40
JOURNAL ARTICLE
Ivica Vrdoljak, Anja Pozaić, Martina Bituh, Ninoslav Leko, Tea Vrdoljak Margeta, Draško Pavlović, Ines Panjkota Krbavčić
BACKGROUND: Chronic kidney disease associated mineral bone disorder (CKD-MBD) is one of the major causes of excess morbidity and mortality in hemodialysis patients. The purpose of this study was to investigate whether education about dietary intakes and specific food processing methods affect serum calcium and PTH concentrations in hemodialysis patients. METHODS: Forty-seven hemodialysis patients were randomly divided into a control and an intervention group. All participants were on individualized phosphate binder therapy...
September 13, 2024: Journal of Nephrology
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