journal
https://read.qxmd.com/read/36959163/changes-in-the-long-noncoding-rna-expression-profile-in-the-development-of-the-embryonic-external-ear-after-bmp5-gene-mutation
#1
JOURNAL ARTICLE
Wei Liu, Shengyang Jin, Lin Lin, Qinghua Yang, Haiyue Jiang
To understand the role of long noncoding RNA (lncRNA) gene regulation and changes in expression in mouse external ear embryonic development, a BMP5 short ear mouse model was used to measure changes in the lncRNA expression in the outer ear tissues of mouse embryos developed to E15.5 and E17.5 using high-throughput sequencing. The changes in lncRNA expression were identified using find_circ and CIRI2 software, and functional analyses were performed using gene ontology and the Kyoto encyclopedia of genes and genomes annotations of differentially expressed lncRNAs...
March 24, 2023: Journal of Craniofacial Surgery
https://read.qxmd.com/read/36959120/modelling-brain-in-a-chip
#2
JOURNAL ARTICLE
Nureddin Ashammakhi, Rohollah Nasiri, Christopher H Contag, Anna Herland
No abstract text is available yet for this article.
March 24, 2023: Journal of Craniofacial Surgery
https://read.qxmd.com/read/36959116/cosmetic-open-rhinoplasty-in-acute-nasal-bone-fracture-with-pre-existing-deformity
#3
JOURNAL ARTICLE
Yong-Ha Kim, Won Seob Lee, Jae-Won Kim, Kyu-Jin Chung
The simultaneous reduction of nasal bone fracture and cosmetic rhinoplasty is a challenging procedure, because of fracture severity and skeletal instability. Our aim was to investigate the surgical strategy and outcomes of cosmetic rhinoplasty according to the pre-existing nasal deformity when performing simultaneous reduction of nasal bone fracture and cosmetic rhinoplasty. In total, 71 patients who underwent cosmetic rhinoplasty were included. All patients were categorized according to pre-existing deformity, dorsal hump and irregularities, and deviation of the nose, wide nose, and flat nasal dorsum...
March 24, 2023: Journal of Craniofacial Surgery
https://read.qxmd.com/read/36949038/a-22-year-experience-of-cleft-lip-and-palate-surgery-in-suburban-indonesia
#4
JOURNAL ARTICLE
Melia Bogari, Agus S Budi
No abstract text is available yet for this article.
March 23, 2023: Journal of Craniofacial Surgery
https://read.qxmd.com/read/36949035/subjective-and-objective-evaluation-of-speech-in-adult-patients-with-repaired-cleft-palate
#5
JOURNAL ARTICLE
Qun Lou, Xudong Wang, Yang Chen, Guomin Wang, Liping Jiang, Qiong Liu
OBJECTIVE: To explore the speech outcomes of adult patients with repaired cleft palate through subjective perception evaluation and objective acoustic analysis, and to compare the differences in pronunciation characteristics between speakers with complete velopharyngeal closure (VPC) and velopharyngeal insufficiency (VPI) patients. PARTICIPANTS AND INTERVENTION: Subjective evaluation indicators included speech intelligibility, nasality and consonant missing rate, for objective acoustic analysis, we used speech sample normalization and objective acoustic parameters included normalized vowel formants, voice onset time and the analysis of 3-dimensional spectrogram and spectrum, were carried out on speech samples produced by 3 groups of speakers: (a) speakers with velopharyngeal competence after palatorrhaphy (n=38); (b) speakers with velopharyngeal incompetence after palatorrhaphy (n=70), (c) adult patients with cleft palate (n=65) and (d) typical speakers (n=30)...
March 23, 2023: Journal of Craniofacial Surgery
https://read.qxmd.com/read/36944605/evaluation-of-facial-trauma-scars-after-treating-by-refining-plastic-surgery-techniques-a-follow-up-study
#6
JOURNAL ARTICLE
Yibing Wu, Zuguang Hua, Yang Xiang, Shengqian Zhu, Weiwei Chen, Peng Wei
BACKGROUND: Although early debridement and refining plastic surgery techniques have been shown to be effective in the treatment of facial scars after trauma, their postoperative outcomes have not been quantitatively evaluated by the relevant Scar Cosmesis Assessment and Rating (SCAR) Scale. This study was designed to provide a fair assessment of the appearance and local symptoms of scars after treatment by refining plastic surgery techniques and to share the operational skills of surgical repairs...
March 22, 2023: Journal of Craniofacial Surgery
https://read.qxmd.com/read/36944601/using-a-new-deep-learning-method-for-3d-cephalometry-in-patients-with-cleft-lip-and-palate
#7
JOURNAL ARTICLE
Meng Xu, Bingyang Liu, Zhaoyang Luo, Hengyuan Ma, Min Sun, Yongqian Wang, Ningbei Yin, Xiaojun Tang, Tao Song
Deep learning algorithms based on automatic 3-dimensional (D) cephalometric marking points about people without craniomaxillofacial deformities has achieved good results. However, there has been no previous report about cleft lip and palate. The purpose of this study is to apply a new deep learning method based on a 3D point cloud graph convolutional neural network to predict and locate landmarks in patients with cleft lip and palate based on the relationships between points. The authors used the PointNet++ model to investigate the automatic 3D cephalometric marking points...
March 22, 2023: Journal of Craniofacial Surgery
https://read.qxmd.com/read/36944600/nasal-construction-in-congenital-arhinia-due-to-novel-smchd1-gene-variant
#8
JOURNAL ARTICLE
Marie Bargiela, Janina Kueper, Arman T Serebrakian, MaKenna R Browne, Susan Brogna, Zachary S Peacock, Branko Bojovic, Natalie D Shaw, Eric C Liao
Arhinia, or congenital absence of the nose, is an exceedingly rare anomaly caused by pathogenic variants in the gene SMCHD1. Arhinia exhibits unique reconstructive challenges, as the midface is deficient in skeletal and soft tissue structures. The authors present 2 related patients with arhinia who harbor a novel SMCHD1 gene variant and illustrate their surgical midface and nasal construction. Targeted sequencing was carried out on DNA samples from the 2 affected patients, 1 anosmic and 1 healthy parent, to identify variants in exons 3 to 13 of SMCHD1...
March 22, 2023: Journal of Craniofacial Surgery
https://read.qxmd.com/read/36944599/application-of-vacuum-formed-cyst-plug-in-conservative-treatment-of-jaw-cyst-in-children
#9
JOURNAL ARTICLE
Qichao Zhao, Shanshan Du, Jingwen Wang, Yi Zhao
Fenestration decompression, which can protect important anatomic structures and reduce surgical risk is the most preferred way for the treatment of jaw cysts in children, and wearing a cyst plug after the operation is the key to success. To enhance the retention of the cyst plug and promote the healing of the cyst, our team designed the vacuum-formed cyst plug to replace the classic one. This article presents a case of a jaw cyst in a 6-year-old girl who wore the vacuum-formed cyst plug after the fenestration decompression...
March 22, 2023: Journal of Craniofacial Surgery
https://read.qxmd.com/read/36941242/differences-in-the-osseous-ultrastructure-in-2-differing-etiologies-of-eagle-syndrome-a-micro-ct-study
#10
JOURNAL ARTICLE
Nils Heim, Felix B Warwas, Lamia Singer, Franz-Josef Kramer, Christoph Bourauel, Werner Götz
OBJECTIVES: Eagle syndrome is a rare disease caused by an elongated styloid process (type I) or ossified stylohyoid ligament (type II) and causes a heterogeneous symptom complex, ranging from pain in the throat and neck to neurological symptoms and neurovascular entrapment. The 2 different types present differing shapes and ultrastructures and cause different symptoms. This study aimed to distinguish the 2 types by investigating the structures by micro-computed tomography. METHODS: Micro-computed tomography was performed and evaluated in n=10 resected styloid processes from patients diagnosed with Eagle syndrome...
March 21, 2023: Journal of Craniofacial Surgery
https://read.qxmd.com/read/36941237/transillumination-of-an-anterior-fontanelle-dermoid-cyst
#11
JOURNAL ARTICLE
Darshan Shastri, Wilson A M Fisher, Jeyhan Wood, Carolyn Quinsey
Dermoid cysts are slowly growing benign lesions of ectodermal tissue that often occur in the anterior fontanelle. Clinicians often rely on a negative transillumination test to begin the process of correctly diagnosing a dermoid cyst. However, here the authors present a case of a 7-month-old girl who presents with a transilluminating dermoid cyst.
March 21, 2023: Journal of Craniofacial Surgery
https://read.qxmd.com/read/36941235/extraordinary-complication-of-covid-19-swab-testing-csf-rhinorrhea
#12
JOURNAL ARTICLE
Uzdan Uz, Kivanç Günhan, Yüksel Pabuşcu, Sabri Mutlu, Uğur Kamiloğlu
Coronavirus disease 2019 (COVID-19) is a highly contagious disease that has reached pandemic status. The diagnosis of COVID-19 is made using the polymerase chain reaction test to evaluate a swab taken from the naso/oro-pharyngeal area. Since COVID-19 is still a pandemic, it is thought that the use of this diagnostic test will be on the agenda for a while. A patient with COVID-19 symptoms presented with unilateral cerebrospinal fluid rhinorrhea after a nasopharyngeal swab test. Although nasopharyngeal swabs are taken very frequently, the complication rate is very low...
March 21, 2023: Journal of Craniofacial Surgery
https://read.qxmd.com/read/36941233/bilateral-transient-dilated-and-fixed-pupils-after-microvascular-decompression-rare-clinical-experience
#13
JOURNAL ARTICLE
Linkai Wang, Haonan Fan, Xiaohui Xu, Sheng Su, Weijian Feng, Chunlai Wu, Yili Chen
Microvascular decompression (MVD) has a satisfactory safety, and it is the only surgical treatment for neurovascular compression diseases, such as hemifacial spasm, trigeminal neuralgia, and glossopharyngeal neuralgia, from the perspective of etiology. Bilateral dilated and fixed pupils have long been regarded as a sign of life threatening, which is common in patients with cerebral herniation due to cranial hypertension. However, transient dilated pupils after MVD have not been previously reported. Here, we presented 2 patients with bilateral transient dilated and fixed pupils after MVD and discussed the possible etiologies through the literature review...
March 21, 2023: Journal of Craniofacial Surgery
https://read.qxmd.com/read/36941231/prelamination-of-anterolateral-thigh-osseocutaneous-flap-with-fibula-for-the-reconstruction-of-zygomatic-arch-defects-after-facial-trauma
#14
JOURNAL ARTICLE
Zhongkai Ma, Grace Paka Lubamba, Chunjie Li
Complex facial trauma usually results in significant physical, esthetical, functional, and psychological damage. Nowadays, tissue flap transfer is the most effective and common treatment for the reconstruction of facial defects. Among them, the prelaminated flap has a bigger role in reconstructing massive facial defects. In this report, the authors have described a case of a 48-year-old man who presented a complex defect of tissue and deformity in the oral and maxillofacial region because of traffic accident trauma...
March 21, 2023: Journal of Craniofacial Surgery
https://read.qxmd.com/read/36939920/facial-asymmetry-phenotypes-in-adult-patients-with-unilateral-cleft-lip-and-palate-and-skeletal-class-iii-malocclusion-using-principal-component-analysis-and-cluster-analysis
#15
JOURNAL ARTICLE
Mihee Hong, Haeddeuri Kim, Il-Hyung Yang, Jin-Young Choi, Jong-Ho Lee, Myung-Jin Kim, Jee Hyeok Chung, Sukwha Kim, Seung-Hak Baek
The purpose of this study was to classify and characterize facial asymmetry (FA) phenotypes in adult patients with unilateral cleft lip and palate (UCLP) and skeletal class III malocclusion. The samples comprised 52 adult UCLP patients (36 men and 16 women; mean age, 22.43 y) who had undergone orthognathic surgery for correction of class III malocclusion. After measurement of 22 cephalometric parameters in posteroanterior cephalograms taken 1 month before orthognathic surgery, principal component analysis was performed to obtain 5 representative parameters [deviation (mm) of ANS (ANS-dev), maxillary central incisor contact point (Mx1-dev), and menton (Me-dev); cant (degree) of the maxillary anterior occlusal plane (MxAntOP-cant) and mandibular border (MnBorder-cant)]...
March 20, 2023: Journal of Craniofacial Surgery
https://read.qxmd.com/read/36939862/fusion-of-lateral-calvarial-sutures-on-volume-rendered-computed-tomography-reconstructions-in-patients-with-known-craniosynostosis
#16
JOURNAL ARTICLE
C Corbett Wilkinson, Katherine Belanger, Rasha Elbadry, Jessa Hoffman, Megan Ryan, Nicholas V Stence, Sarah J Graber, Thomas Ridder, Ligia Batista, Brooke M French
INTRODUCTION: After treating a child with familial sagittal craniosynostosis, clinocephaly, and bilateral parietomastoid/posterior squamosal suture fusion, the authors wondered if major-suture synostosis and clinocephaly were associated with abnormal fusion of minor lateral calvarial sutures. METHODS: The authors reviewed all preoperative volume-rendered head computed tomography reconstructions performed for craniosynostosis at their institution from 2010 through 2014 and determined whether the sphenoparietal, squamosal, and parietomastoid sutures were open, partially fused, or fused...
March 20, 2023: Journal of Craniofacial Surgery
https://read.qxmd.com/read/36935403/infants-with-trigonocephaly-treated-with-fronto-orbital-remodelling-and-endocortical-positioning-of-resorbable-plates-a-retrospective-cohort-study-including-101-patients
#17
JOURNAL ARTICLE
Sven Zittel, Oliver Ristow, Julius Moratin, Thomas Rückschloß, Jürgen Hoffmann, Ahmed El Damaty, Christian Freudlsperger, Michael Engel
PURPOSE: Fronto-orbital remodeling is the gold standard for surgical treatment of metopic synostosis in many craniofacial centers. For fixation, resorbable materials are widely used. Because of swelling during resorption, the positioning of the plates can be relevant. Therefore, the goal of this study was to investigate whether there are limitations to endocortical positioning of resorbable plates. METHODS: In this retrospective study, all patients with metopic craniosynostosis resulting in trigonocephaly, who were treated with a standardized fronto-orbital remodeling and endocortical positioning of resorbable plates, between February 2012 and December 2019 were included...
March 20, 2023: Journal of Craniofacial Surgery
https://read.qxmd.com/read/36935402/the-assessment-of-intermaxillary-fixation-and-open-reduction-using-skeletal-anchorage-system-compared-with-arch-bar-in-mandible-fracture-based-on-ct-image
#18
JOURNAL ARTICLE
Han Ick Park, Young-Jin Choi, Jee-Ho Lee
BACKGROUND: There are many different techniques to achieve intermaxillary fixation (IMF) for open reduction of mandible fractures. The arch bar has long been used as the gold standard of IMF to assist open reduction. However, owing to its long operating time, risk of needle stick injury, and gingival trauma, surgeons looked into different treatment options for IMF, such as the skeletal anchorage system (SAS). Therefore, this study aimed to compare the stability between IMF with arch bar and IMF with SAS based on computed tomography image...
March 20, 2023: Journal of Craniofacial Surgery
https://read.qxmd.com/read/36935399/investigation-of-flaviviruses-emerging-in-brazil-as-etiology-factor-in-nonsyndromic-orofacial-cleft
#19
JOURNAL ARTICLE
Kaique C P Silva, Thiago S Messias, Simone Soares
Brazil has one of the largest forest areas on the planet and the potential for the emergence of new diseases. In turn, orofacial clefts, especially cleft lip and or palate (CL/P), are characterized as congenital malformations and may be associated with genetic and environmental factors. The present study aimed to investigate in silico the flavivirus's potential to emerge in Brazil as an etiology of CL/P. A scoring method was created based on literature and nucleotide similarity analysis. An integrative analysis of the literature was performed to answer the questions through the databases PubMed/MEDLINE, SciELO, LILACS, and Google Scholar to have a more significant number of results...
March 20, 2023: Journal of Craniofacial Surgery
https://read.qxmd.com/read/36935396/an-optimizing-surgical-procedures-for-correcting-severe-constricted-ears-helix-costal-cartilage-scaffold-combined-with-v-y-advanced-flap
#20
JOURNAL ARTICLE
Huanhuan Wu, Guoxuan Dong, Tun Liu, Jin Qian, Bingqing Wang, Yue Wang
PURPOSE: A constricted ear is a deformity that is distinguished by curling of the upper portion of the ear, which includes the helix, scapha, and antihelix. The treatment for severely constricted ears seems to be quite invasive. To reduce invasiveness and fully utilize the folded cartilage, the authors used a helix costal cartilage scaffold combined with a single V-Y advanced flap in the correction of Tanzer type IIB constricted ear deformity to investigate the clinical effect. MATERIALS AND METHODS: From 2020 to 2021, autologous costal cartilage helix stent combined with local V-Y advanced flap was applied to correct the constricted ear malformation in 18 patients admitted to the Plastic Surgery Hospital of the Chinese Academy of Medical Sciences...
March 20, 2023: Journal of Craniofacial Surgery
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