Michael K Leuchter, Cole Citrenbaum, Andrew C Wilson, Tristan D Tibbe, Nicholas J Jackson, David E Krantz, Scott A Wilke, Juliana Corlier, Thomas B Strouse, Gil D Hoftman, Reza Tadayonnejad, Ralph J Koek, Aaron R Slan, Nathaniel D Ginder, Margaret G Distler, Hewa Artin, John H Lee, Adesewa E Adelekun, Evan H Einstein, Hanadi A Oughli, Andrew F Leuchter
Clinical outcomes of repetitive transcranial magnetic stimulation (rTMS) for treatment of treatment-resistant depression (TRD) vary widely and there is no mood rating scale that is standard for assessing rTMS outcome. It remains unclear whether TMS is as efficacious in older adults with late-life depression (LLD) compared to younger adults with major depressive disorder (MDD). This study examined the effect of age on outcomes of rTMS treatment of adults with TRD. Self-report and observer mood ratings were measured weekly in 687 subjects ages 16-100 years undergoing rTMS treatment using the Inventory of Depressive Symptomatology 30-item Self-Report (IDS-SR), Patient Health Questionnaire 9-item (PHQ), Profile of Mood States 30-item, and Hamilton Depression Rating Scale 17-item (HDRS)...
March 25, 2024: International Psychogeriatrics