Shankar Tumati, Nathan Herrmann, Jaime Perin, Paul B Rosenberg, Alan J Lerner, Jacobo Mintzer, Prasad R Padala, Olga Brawman-Mintzer, Christopher H van Dyck, Anton P Porsteinsson, Suzanne Craft, Allan Levey, David Shade, Krista L Lanctôt
OBJECTIVES: Among participants with Alzheimer's disease (AD) we estimated the minimal clinically important difference (MCID) in apathy symptom severity on three scales. DESIGN: Retrospective anchor- and distribution-based analyses of change in apathy symptom scores. SETTING: Apathy in Dementia Methylphenidate Trial (ADMET) and ADMET 2 randomized controlled trials conducted at three and ten clinics specialized in dementia care in United States and Canada, respectively...
September 19, 2024: International Psychogeriatrics