Journals International Journal of STD &...

International Journal of STD & AIDS
Zhidi Gao, Guangyong Xu, Su Wang, Na Guo, Yang Yu, Xiaoni Wang
This paper seeks to determine the effect of combination anti-PD-1 and antiretroviral therapy (ART) on people living with HIV (PLWH) with advanced gastric cancer. In our case, a PLWH with recurrent locally advanced gastric cancer was treated with anti-PD-1 inhibitor and ART. A significant reduction in tumor lesions (as demonstrated by contrast-enhanced CT imaging) and a better quality of life were achieved following treatment. There have been limited studies on the treatment of PLWH with advanced gastric cancer...
April 21, 2024: International Journal of STD & AIDS
Vanessa M McMahan, Dana L Atkins, Smitty Buckler, Lauren R Violette, Lisa Niemann, Noah Frank, Kimiam Waters, Luis Enrique Herrera Perales, Luis Viquez, Elyse Tung, Joanne D Stekler
BACKGROUND: Methamphetamine is associated with increased HIV risk and suboptimal adherence to pre-exposure prophylaxis (PrEP). Interventions to support PrEP adherence for people who use methamphetamine are needed. METHODS: We evaluated peer navigation to support adherence among people initiating PrEP who use methamphetamine. The <u>H</u>IV Prevention in <u>M</u>ethamphetamine <u>U</u>sers (HMU!) study enrolled participants from May 2018-January 2022 in Seattle, WA, and followed them for 6 months...
April 17, 2024: International Journal of STD & AIDS
Jaheersha Pakran, Amal Mohammed Alsaberi, Amani AlFalasi, Tarek Mohamed Karam Husein Ibrahim, Amel Abdalla Eisa Fadl Alnuaimi, Srikumar Goturu, Muneer Mohamed, Reena Mary Abraham, Vidya Lakshmi Sundaramurthi, Aneesh Kunnath Parambath, Beena Jose, Divya Kamat, Thencheri Cheriath Satish, Juwariya Tasneem Syeda, Lubna Gul, Rohini Mathias, Sajeela Rasheed Vattiyamveetil, Shaheela Backar, C Vijay Krishna, Laila Al Dhabal
BACKGROUND: MPOX (Monkeypox) viral infection, a zoonotic disease previously confined to the African sub-continent, has caught attention worldwide recently due to its resurgence in a new 'avatar' among urban communities. Dermatologists in the U. A. E. started to see patients with fever and a self-limiting pustular necrotic rash that was negative for all other infectious investigations. METHODS: We performed a prospective observational multicenter clinical study of the demographics, skin manifestations, and outcomes of patients presenting with necrotic pustular lesions and/or fever...
April 12, 2024: International Journal of STD & AIDS
Thibaut Vanbaelen, Irith De Baetselier, Sheeba Santhini Manoharan-Basil, Chris Kenyon
OBJECTIVE: Tetracycline and macrolide resistance are frequently linked in streptococci and other species. We aimed to assess the association between doxycycline use and azithromycin MICs in oral streptococci. METHODS: Linear regression was used to assess the association between doxycycline use in the prior year and the median MIC per participant of oral streptococcal colonies isolated at the baseline visit of the ResistAZM study. The analysis controlled for receipt of other antimicrobials as well as time since antimicrobial consumption...
April 12, 2024: International Journal of STD & AIDS
Daniel Augusto Barnabé Nobre, Mariela Dutra Gontijo Moura, José Alcides Almeida de Arruda, Fernanda Aragão Felix, Priscilla Barbosa Diniz, Eliza Carla Barroso Duarte, Lucas Guimarães Abreu, Ricardo Santiago Gomez, Ricardo Alves Mesquita
BACKGROUND: This study evaluated the presence of Epstein-Barr virus type 1 (EBV-1) DNA in patients living with HIV, before and after three different topical therapy protocols for oral hairy leukoplakia (OHL). METHODS: The sample consisted of five patients treated with topical solution of 25% podophyllin resin; six with 25% podophyllin resin plus 5% acyclovir cream; and four with 25% podophyllin resin plus 1% penciclovir cream. DNA was extracted from OHL scrapings and amplified by the PCR using specific primers for EBV-1 (EBNA-1)...
April 12, 2024: International Journal of STD & AIDS
Malin Bergstrom, Anika Rahim, Jane Akodu, Gavin Marshall, Cora Harrison, Louisa Penrose, Marc Ci Lipman, Robert F Miller
Receipt of nebulised pentamidine in people with HIV was audited to identify if individuals were appropriately receiving nebulised pentamidine, and whether national guidelines were being followed when prophylaxis was commenced and discontinued. Of 76 people with who received nebulised pentamidine, the main indication for starting nebulised pentamidine was a co-trimoxazole adverse drug reaction. Co-trimoxazole desensitization was not attempted before starting nebulised pentamidine. The main indication for stopping nebulised pentamidine prophylaxis was when immune reconstitution occurred...
April 12, 2024: International Journal of STD & AIDS
Nina Yancheva-Petrova, Rusina Grozdeva, Daniel Ivanov, Dimitar Strashimirov
In the 1970s, human papillomaviruses (HPV) were ascertained as the aetiologic agents of cervical carcinoma. Subsequently, an association with HPV was established in other epithelial tumours, including squamous cell carcinoma of the head and neck (HNSCC). HPV has demonstrated a high potential for inducing oropharyngeal tumours, with HPV-16 infection posing a significant oncogenic risk. People living with HIV (PLWH) are identified as being at a higher risk of HPV infection and the subsequent development of HPV-associated tumours of the oropharynx...
April 11, 2024: International Journal of STD & AIDS
Akel Azzi, Carine Chartouni, Racha Ibrahim, Zeina Bou Chebel, Elie Haddad, Nabil Chehata, Jacques Choucair, Gebrael Saliba
BACKGROUND: In the evolving HIV landscape, the Middle East and Northern Africa (MENA) grapples with data gaps, hindering the 95-95-95 targets. Lebanon, despite progress, falls short. Our study addresses Pre-exposure Prophylaxis (PrEP) gaps for effective HIV prevention. METHODS: Surveying 410 participants via snowball sampling and an online questionnaire, we analyzed data with chi-square and regression over 5 months for insights into PrEP awareness and readiness...
March 27, 2024: International Journal of STD & AIDS
Bryony Broster, Amanda Clarke, Collins Iwuji, Suneeta Soni
INTRODUCTION: Possible resistance to recommended treatments for scabies has emerged recently. In response to anecdotal reports of a recent increase in treatment failure with permethrin, the British Association for Sexual Health and HIV (BASHH) released a statement alerting members to this. AIMS: To examine attendances and the treatment pathways for scabies cases seen at local sexual health clinics. METHODOLOGY: A case note review of scabies attendances between January 2017 and December 2023 was conducted...
March 27, 2024: International Journal of STD & AIDS
Patrick C Eustaquio, Corrina P Azarcon, J Carlo M Artiaga
No abstract text is available yet for this article.
March 27, 2024: International Journal of STD & AIDS
Thorsten M Leucker, Tarek Harb, Gary Gerstenblith, David D Celentano, Efthymios Ziogos, Glenn Treisman, Raul N Mandler, Jag Khalsa, Man Charurat, Shenghan Lai, Hong Lai
BACKGROUND AND AIMS: People with HIV (PWH) whose disease is controlled on anti-retroviral regimens remain at an increased risk for coronary artery disease (CAD). Traditional cardiovascular risk factors do not fully explain the residual risk in PWH suggesting contributions from nontraditional factors. Homocysteine (Hcy) may be one of these as prior work in adults without HIV demonstrate that Hcy may impair endothelial function by decreasing the availability of nitric oxide, promoting the development of atherosclerosis...
March 26, 2024: International Journal of STD & AIDS
Talent Maphosa, Kelsey Mirkovic, Rachel A Weber, Godfrey Musuka, Munyaradzi P Mapingure, Julia Ershova, Rebecca Laws, Trudy Dobbs, William Coggin, Charles Sandy, Tsitsi Apollo, Owen Mugurungi, Michael Melchior, Mansoor S Farahani
BACKGROUND: Tuberculosis remains the leading cause of death by an infectious disease among people living with HIV (PLHIV). TB Preventive Treatment (TPT) is a cost-effective intervention known to reduce morbidity and mortality. We used data from ZIMPHIA 2020 to assess TPT uptake and factors associated with its use. METHODOLOGY: ZIMPHIA a cross-sectional household survey, estimated HIV treatment outcomes among PLHIV aged ≥15 years. Randomly selected participants provided demographic and clinical information...
March 22, 2024: International Journal of STD & AIDS
Blanca Santos-Latasa, Francisco-Javier Bru-Gorraiz, Alejandro Martin-Gorgojo
The occurrence of cysts and papulopustules along the midline penile raphe, as a complication of gonococcal urethritis, is considered an exceptional presentation. These lesions are related to developmental abnormalities in the fusion of the lower portion of the ventral abdominal wall during embryogenesis, which create small pathways along the raphe of the penis, prone to secondary infection in the presence of gonococcal urethritis. We present the case of a 25-year-old male who experienced these lesions twice, coinciding with two separate episodes of gonococcal urethritis following unprotected sex...
March 20, 2024: International Journal of STD & AIDS
Guoxi Cai, Yufen Liu, Jinman Zhuang, Zishan Chen, Yixiao Lu, Jiwen Wu, Zhijian Hu, Jianping Zhang, Fei He
BACKGROUND: Heterosexual contact is the primary mode of HIV transmission in China and commercial sex is thought to play a crucial role in China's epidemic. Female sex workers (FSWs) in China tend to be either brothel-based (BSWs) or street-based (SSWs), but few studies have investigated the differences between these important segments of this difficult-to-reach, high-risk population. Our aim was to explore the differences between SSWs and BSWs in terms of socio-demographic characteristics, sexual and risky practices, HIV/STI-related knowledge, health services, HIV/STI prevalence and other aspects...
March 20, 2024: International Journal of STD & AIDS
Thibaut Vanbaelen, Sheeba S Manoharan-Basil, Chris Kenyon
BACKGROUND: Selective mass treatment of STIs may lead to a durable reduction in the prevalence of STIs or a temporary reduction associated with an increased probability of antimicrobial resistance emerging. METHODS: We searched PubMed and Google Scholar for studies evaluating the impact of mass STI treatment on the long-term prevalence of chlamydia, gonorrhoea, syphilis and chancroid. The primary outcomes were the long term (≥3 months post the intervention) impact of the intervention on prevalence/incidence of the STI and on antimicrobial resistance...
March 20, 2024: International Journal of STD & AIDS
Iris Harrison, Kathryn DeSear, Barbara A Santevecchi, Veena Venugopalan, Kartikeya Cherabuddi, Nicole Iovine, Nila Radhakrishnan
A man with advanced HIV presented with verrucous plaques 2-3 months after initial mpox infection. He received two courses of tecovirimat without resolution of initial mpox lesions and development of new lesions raising concern for resistance. He was treated with two doses of brincidofovir and demonstrated improvement 6 months later.
March 19, 2024: International Journal of STD & AIDS
Luca Valtellini, Stefano Ramoni, Susanna Benardon, Francesco Rogari, Andrea Licandro, Carlo G Carrera, Angelo V Marzano
No abstract text is available yet for this article.
March 16, 2024: International Journal of STD & AIDS
Handan Wand, Jayajothi Moodley, Tarylee Reddy, Sarita Naidoo
BACKGROUND: South African women have the highest burden of HIV infections globally. We investigated the temporal trends and the impact of key factors associated with HIV diagnosis among a nationally representative cohort of South African women. METHODS: Total of 24,657 women who participated in the National HIV, Behaviour and Health Surveys conducted from 2002-to-2017. RESULTS: Despite decades-long prevention efforts, we observed a significant increase in HIV prevalence over time (22% in 2002 to 21% in 2005-2008 and 29% in 2012-2017)...
March 16, 2024: International Journal of STD & AIDS
Putri L Karim, Inda A Aryani, Suroso A Nugroho, Irsan Saleh, Lisa Dewi, Yuli Kurniawati, Fitriani Fitriani
BACKGROUND: Syphilis infection can be asymptomatic and difficult to diagnose based on clinical symptoms. Early detection and treatment are critical for preventing and controlling syphilis as well as long-term serious complications. A serological examination based on the diagnostic algorithm was used to confirm the diagnosis of syphilis. Syphilis is frequent in high-risk groups, such as men who have sex with men (MSM). Treponema pallidum (TP) rapid can be used for early syphilis detection...
March 13, 2024: International Journal of STD & AIDS
Izuchukwu Ezeh, Andrew Tomkins
We report the case of a young man who has never had any sexual contact presenting with a large scrotal lump with secondary bacterial infection. He reported no prior warts - genital or cutaneous. On examination, he had a large pink cauliform mass on the scrotum with four smaller but similar satellite lesions. Appearances were thought to be consistent with giant condyloma of Buschke and Lowenstein. Once superinfection was treated with oral antibiotics, he had a trial of imiquimod without success and was then referred to urology...
March 8, 2024: International Journal of STD & AIDS
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