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Revista Española de Enfermedades Digestivas

Rocío Aller, Beatriz Burgueño Gomez, Rebeca Sigüenza, Conrado Fernández-Rodríguez, Natalia Fernández, Beatriz Antolín, Miguel Durà, María Pina, Sara Lorenzo, Concepción García, Daniel de Luis Román
BACKGROUND AND AIMS: non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder in the western world. Although NAFLD prevalence is higher in patients with a BMI > 25 kg /m2, it is unclear if there are differences between overweight and obese patients. The associated biochemical, dietary and genetic parameters were compared between overweight and obese patients with NAFLD. METHODS: patients with biopsy-proven NAFLD (n = 203) were enrolled in a cross-sectional study...
February 11, 2019: Revista Española de Enfermedades Digestivas
Wei Zhang, Xinyan Zhao, Jian Huang, Xiaojuan Ou, Jidong Jia
Alagille syndrome (ALGS) is an autosomal-dominant multisystem disorder caused by mutations in Jagged 1 (JAG1) or NOTCH2. The penetrance is low but highly variable. It is almost exclusively diagnosed in children with cholestasis and, more rarely, in their adult relatives. Here, we report the case of a patient diagnosed with ALGS in adulthood. The patient was a 28-year-old male who presented with characteristic facial features, an eye abnormality, chronic cholestasis with bile duct paucity on liver biopsy, atrial defects and stenosis of the left internal carotid artery...
February 11, 2019: Revista Española de Enfermedades Digestivas
Maite Betés, Santiago González Vázquez, Alejandro Bojórquez, María Dolores Lozano, José Ignacio Echeveste, Laura García Albarrán, Miguel Muñoz Navas, Jose Carlos Súbtil
BACKGROUND AND OBJECTIVES: there are few published data on the use of EUS guided fine-needle aspiration in secondary pancreatic lesions. We describe the largest series published so far in a European country. PATIENTS AND METHODS: a retrospective review of the cases identified in our institution from 2004 to 2016 has been recorded. The clinical data are described, comparing the latency period from the primary tumor diagnosis to the detection of the pancreatic metastasis and the survival of patients according to the cytological diagnosis...
February 11, 2019: Revista Española de Enfermedades Digestivas
Mariana Tavecchia, Aurora Burgos García, Pedro de María Pallares
A colonoscopy was performed as part of a colorectal screening program on a 77-year-old female with positive fecal occult blood test. During withdrawal, two metallic elongated foreign bodies, around 20 mm in length were found pinned into the transverse colon and rectal wall. A computed tomography with multiplanar reconstruction showed two metallic density T-shaped foreign bodies that resembled intrauterine devices (IUDs) that penetrated the intestinal wall , which ruled out other complications. The patient confirmed a previous loss of an IUD device 35 years previously and underwent a second IUD insertion a few years later...
February 11, 2019: Revista Española de Enfermedades Digestivas
Carolina Moreno Márquez, María Dolores Galván Fernández, Xaira Cortés Sañudo, Ángel Caunedo Álvarez
We present a case of arcuate ligament syndrome diagnosed in a 23-year-old patient with epigastric pain, vomiting and weight loss, using Doppler ultrasound and CT-angiography, treated by surgical resection of the ligament with complete resolution of symptoms. In addition, incidentally the patient was diagnosed with a nutcracker syndrome, without clinical repercussions.
February 11, 2019: Revista Española de Enfermedades Digestivas
Pablo Sánchez Acedo, Guillermo Viteri Ramírez, Javier Herrera Cabezón, Antonio Tarifa Castilla
Pancreas divisum is a congenital anomaly present in 5-10% of the population and is usually asymptomatic. Pancreatic intraductal papillary mucinous neoplasms (IPMN) are mucinous cystic tumors that have malignant potential and are classified according to their location as IPMN of the main duct, branch duct or mixed type. Larger lesions and those originating in the main duct have an increased risk of malignancy. The real incidence is unknown as most lesions are asymptomatic.
February 11, 2019: Revista Española de Enfermedades Digestivas
Miguel Fraile López, Rodrigo Ugalde Herrá, Fernando Fernández Cadenas
Endoscopic full-thickness resection (EFTR) is a new technique for the resection of colonic lesions with limitations for other techniques such as endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD) due to fibrosis, the location of the lesion or invasion depth. In addition, techniques such as ESD require a long learning curve and unfortunately they are not fully implemented in Western countries. EFTR has numerous indications, which are expanding daily. The Full-Thickness Resection Device (FTRD) is a promising tool, although it has many limitations and is associated with some risks...
February 11, 2019: Revista Española de Enfermedades Digestivas
Maria Curieses Luengo, Claudia F Consiglieri, Manuel Puga, Joan B Gornals
INTRODUCTION: the appearance of the lumen-apposing metal stent (LAMS) has meant an authentic revolution. To date, the results are promising but it is necessary to note the technical incidents and LAMS-related complications. CASE REPORT: an EUS-transmural guided drainage using a HotAXIOS was planned for a 36-year-old man with oral intolerance due to a voluminous walled-off necrosis. The distal flange was left in the collection, but a total distal malposition occurred during the proximal flange delivery, despite correct apposition with visualization of the black mark...
February 11, 2019: Revista Española de Enfermedades Digestivas
Eduardo Espinet Coll, Gontrand López-Nava Breviere, Javier Nebreda Durán, Carlos Marra-López Valenciano, Román Turró Arau, José Miguel Esteban López-Jamar, Miguel Muñoz-Navas
During the last years we have been witnessing a significant increase in the number and type of bariatric endoscopic techniques: we have different types of balloons, suture systems, injection of substances and malabsorptive prosthesis, etc. Also, some endoscopic revisional procedures for patients with weight regain after bariatric surgery have been incorporated. This makes it necessary to protocolize, position and regularize all these techniques, through a consensus that allows their clinical application with the maximum medical rigor and scientific evidence available...
January 18, 2019: Revista Española de Enfermedades Digestivas
Felipe Martínez-Alcalá García, José Manuel Pérez Pozo, Felipe Martínez Alcalá
A 63-year-old female with a Nissen funduplication that was diagnosed nine years previously presented with abdominal pain, weight loss and occasional dysphagia of a few months duration. A computed tomography (CT) scan identified an extensive gastric tumor with a subtle curvature and cardia with distal esophagus circumferential enlargement. Gastroscopy identified gastric linitis plastica with many attached residues. The biopsy was compatible with inflammatory changes. A linear echoendoscopy identified an area at the cardia level that was compatible with a foreign body with a lineal hyperechoic irregular focus...
January 11, 2019: Revista Española de Enfermedades Digestivas
Javier A Cienfuegos, Enrique Perez-Cuadrado Martínez
At the beginning of 2019 we wish to inform our readers and share with them the achievements and objectives of the Editorial Board. With the gradual growth of the journal, and to be more efficient and better serve the scientific societies it represents (Spanish Society of Gastroenterology [SEPD], Spanish Society of Gastrointestinal Endoscopy [SEED] and Spanish Association of Digestive Ultrasonography [AEED]), we made the decision to progressively increase the number of papers per issue, and to adapt manuscript classification to the requirements of Web of Science...
December 21, 2018: Revista Española de Enfermedades Digestivas
Andrew Hart
The two predominant forms of inflammatory bowel disease (IBD) namely Crohn's disease (CD) and ulcerative colitis (UC) can have a significant impact on patients' quality of life and incur major costs in terms of time off work and for therapies. The precise aetiology of IBD is unknown, but is probably due to a combination of: genetic, immunological and environmental factors. The role for the latter is strongly supported by rises in the incidence of IBD in the 20th century, and emergence of both CD and UC in countries in the East...
December 20, 2018: Revista Española de Enfermedades Digestivas
Suxian Chen, Xiong Wang, Baoxin Zhang, Baijing Liu, Hui Pan
BACKGROUND: contrast-enhanced ultrasound (CEUS) is increasingly used to identify vascular complications in patients after liver transplantation. The present study aimed to evaluate the diagnostic accuracy of CEUS using all available data. MATERIALS AND METHODS: relevant studies published before February 2018 were retrieved from PubMed, EMBASE, ScienceDirect and Web of Science. Pooled sensitivity and specificity, diagnostic odds ratio (DOR) and summary receiver operating characteristic curve (SROC) were calculated to estimate the diagnostic performance of CEUS for vascular complications...
December 20, 2018: Revista Española de Enfermedades Digestivas
Sara Andrés Lasheras, Inma Martín Burriel, Carmen Aspiroz, Raúl Carlos Mainar Jaime, Pilar Robres, Eloísa Sevilla, Ed Kuijper, Manuel Chirino Trejo, Rosa Bolea
INTRODUCTION: Clostridium difficile (C. difficile) is a major nosocomial infectious agent in hospitals. Previous studies have addressed the high proportion of infection episodes that are overlooked in health care facilities. OBJECTIVE: the main aim of this study was to characterize C. difficile clinical cases that occurred in a secondary care hospital during a five-month period. MATERIAL AND METHODS: for this purpose, a total of 137 stool samples from the same number of patients with diarrhea were analyzed for the presence of C...
December 20, 2018: Revista Española de Enfermedades Digestivas
Eduardo Valdivielso Cortázar, Javier Redondo Martínez, Pedro Alonso Aguirre
Giant fibrovascular polyps are very ucommon benign lesions. Due its size, they can be lethal, so an early diagnosis is important. A case report and diagnostic - therapeutic issues are described.
December 18, 2018: Revista Española de Enfermedades Digestivas
Noe Quesada-Vázquez
Liraglutide is a long-acting glucagon-like peptide-1 (GLP-1) analog. GLP-1 analogues are used as a second option treatment for type 2 diabetes and weight management in obese patients. Data in the literature suggests an association between GLP-1 agonist use and acute pancreatitis (AP). Furthermore, it has been suggested that acute pancreatitis is a potential complication of liraglutide therapy and liraglutide should be used cautiously in patients at risk of pancreatitis. This case reported herein was a 44-year-old female diagnosed with acute pancreatitis based on 2 of 3 criteria when she presented to the Emergency Department with epigastric pain, which radiated to her back...
December 18, 2018: Revista Española de Enfermedades Digestivas
Tiago Leal, Sofia Carvalho, Juliana M Costa
We read with interest the article by Sevilla Ribota et al1 that described an unexpected finding of a granular cell tumour (GCT) of the rectum, which was removed by band ligation-assisted mucosectomy. We present a similar case of a GCT of the cecum, which was resected using a different endoscopic procedure.
December 18, 2018: Revista Española de Enfermedades Digestivas
Javier Crespo, José María Eiros Bouza, Antonio Javier Blasco Bravo, Pablo Lázaro de Mercado, Antonio Aguilera Guirao, Federico García, Javier García-Samaniego Rey, José Luis Calleja Panero
BACKGROUND: implementing one-step strategies for hepatitis C diagnosis would help shorten the time to treatment access. Thus avoiding disease progression and complications, while facilitating hepatitis C virus (HCV) elimination. OBJECTIVE: to assess the validity and safety of potential one-step strategies for the diagnosis of HCV infection and their associated cost and efficiency. METHODS: the study design is an economic appraisal of efficiency (cost/efficacy) using decision trees and deterministic sensitivity analysis...
December 18, 2018: Revista Española de Enfermedades Digestivas
Irene Jiménez, Miguel Ángel Pacha, David Pares, María Esteve, José Troya, Josep Roca, Jaume Canet, Joan-Francesc Julián, Jaume Fernández-Llamazares
BACKGROUND: the aim of this study was to analyze the clinical results of the multidisciplinary management of elderly patients with colorectal cancer in a single center and to describe postoperative quality of life. METHODS: a comparative study was designed to compare the results and quality of life of patients treated in our center for colon cancer, aged from 80 to 84 years (study group) compared to a control group (aged form 75 to 79 years of age). Morbidity, mortality, oncological results and quality of life were analyzed...
December 14, 2018: Revista Española de Enfermedades Digestivas
Salvador Machlab, Mireia Miquel, Mercedes Vergara, María Rosa Escoda, Meritxell Casas
The use of new oral anticoagulants such as apixaban is increasing. We present the case of an 85-year-old patient who was diagnosed with mixed profile toxic hepatitis due to apixaban use. An etiological study was negative, except for anti-smooth muscle antibodies, and a liver biopsy ruled out autoimmune hepatitis. The patient was assigned a score of 7 on the CIOMS/RUCAM scale, indicating a probable causality. The liver injury improved after the withdrawal of apixaban. A previous meta-analysis reported that the risk of hepatotoxicity does not increase with the use of apixaban, nor were any cases reported in registry studies...
December 10, 2018: Revista Española de Enfermedades Digestivas
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