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Journals Current Opinion in Obstetrics ...

Current Opinion in Obstetrics & Gynecology

https://read.qxmd.com/read/38597457/gender-affirming-care-for-the-minimally-invasive-gynecologic-surgeon
#21
JOURNAL ARTICLE
Sarah Simko, Otilia Popa, Mallory Stuparich
PURPOSE OF REVIEW: Given the current political climate and the release of an updated version of the World Professional Association for Transgender Health's guidelines, this review assesses recent updates in the care of transgender and gender diverse (TGD) patients, specifically related to care provided by gynecologists. RECENT FINDINGS: The number of people identifying as TGD and pursuing gender affirming care is increasing. Contraception for these patients is underdiscussed and high rates of pelvic pain and irregular bleeding were identified...
April 5, 2024: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/38572581/embryology-with-precision-effective-quality-control-in-the-in-vitro-fertilization-laboratory
#22
JOURNAL ARTICLE
Murat Basar, Evrim Unsal, Yagmur Ergun
The purpose of this review is to address the critical need for standardization and clarity in the use of key performance indicators (KPIs) within the realm of in vitro fertilization (IVF), particularly emphasizing the integration of preimplantation genetic testing (PGT) processes. This review is timely and relevant given the persistently modest success rates of IVF treatments, which stand at approximately 30%, and the growing complexity of IVF procedures, including PGT practices. The review synthesizes recent findings across studies focusing on technical and clinical KPIs in embryology and genetic laboratories, identifying gaps in current research and practice, particularly the lack of standardized KPIs and terminology...
April 4, 2024: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/38597425/current-applications-of-artificial-intelligence-in-assisted-reproductive-technologies-through-the-perspective-of-a-patient-s-journey
#23
JOURNAL ARTICLE
Zoran J Pavlovic, Victoria S Jiang, Eduardo Hariton
PURPOSE OF REVIEW: This review highlights the timely relevance of artificial intelligence in enhancing assisted reproductive technologies (ARTs), particularly in-vitro fertilization (IVF). It underscores artificial intelligence's potential in revolutionizing patient outcomes and operational efficiency by addressing challenges in fertility diagnoses and procedures. RECENT FINDINGS: Recent advancements in artificial intelligence, including machine learning and predictive modeling, are making significant strides in optimizing IVF processes such as medication dosing, scheduling, and embryological assessments...
April 2, 2024: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/38431872/editorial-maternal-fetal-medicine-old-foes-and-new-weapons
#24
JOURNAL ARTICLE
Martha Rode, Mark Boddy, Charlotte Conturie
No abstract text is available yet for this article.
April 1, 2024: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/38193300/pharmacotherapy-for-opioid-use-disorder-in-pregnancy
#25
REVIEW
Cassandra J Trammel, Julia Whitley, Jeannie C Kelly
PURPOSE OF REVIEW: Opioid use disorder (OUD) in pregnancy has significantly increased in the last decade, impacting 8.2 per 1000 deliveries. OUD carries significant risk of morbidity and mortality for both the birthing person and neonate, but outcomes for both are improved with opioid agonist treatment (OAT). Here, we describe the recommended forms of OAT in pregnancy, updates to the literature, and alternate OAT strategies, and share practical peripartum considerations for patients on OAT...
April 1, 2024: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/38597510/poor-ovarian-response-classification-systems-in-the-clinical-setting-time-for-an-update
#26
JOURNAL ARTICLE
Andres Reig, Emre Seli
PURPOSE OF REVIEW: Poor ovarian response (POR) remains a key challenge to the success of assisted reproductive technology. Here, we offer a comprehensive review of the two main classification systems for POR, discussing their promises and pitfalls, evaluating their performance, and exploring potential avenues for improving upon these definitions of POR. RECENT FINDINGS: The Bologna criteria represented the first meaningful attempt to create a universal POR definition...
March 28, 2024: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/38597577/gnrh-agonist-trigger-in-poor-prognosis-patients-undergoing-a-multicycle-approach-through-duostim-or-consecutive-stimulations-a-swot-analysis
#27
JOURNAL ARTICLE
Alberto Vaiarelli, Alessandro Ruffa, María Cerrillo, Juan Antonio García-Velasco
PURPOSE OF REVIEW: Identify the most recent and significant evidence regarding the ovulation trigger within the framework of a multicycle approach through DuoStim, providing valuable insights for improving treatment strategies in patients with a poor prognosis. RECENT FINDINGS: The trigger method plays a pivotal role in optimizing in-vitro fertilization (IVF) stimulation, influencing oocyte retrieval and maturation rates, as well as follicle recruitment in consecutive ovarian stimulations such as double stimulation...
March 27, 2024: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/38572695/walking-on-thin-endometrium
#28
JOURNAL ARTICLE
Baris Ata, Begum Mathyk, Savci Telek, Erkan Kalafat
PURPOSE OF REVIEW: Endometrial thickness has been regarded a predictor of success in assisted reproductive technology cycles and it seems a common practice to cancel embryo transfer when it is below a cut-off. However, various cut-offs have been proposed without a causal relationship between endometrial thickness and embryo implantation being established, casting doubt on the current dogma. RECENT FINDINGS: Methodological limitations of the available studies on endometrial thickness are increasingly recognized and better designed studies do not demonstrate a cut-off value which requires cancelling an embryo transfer...
March 21, 2024: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/38324593/not-all-platelet-rich-plasma-are-created-equal
#29
JOURNAL ARTICLE
Manuel Muñoz Cantero
PURPOSE OF REVIEW: This review aims to elucidate potential variations in clinical outcomes resulting from the use of different types of platelet-rich plasma (PRPs) in reproductive medicine. It seeks to explore the reasons behind the diverse results reported in various studies and assess the general features distinguishing different PRP formulations. RECENT FINDINGS: PRPs have found applications across diverse medical fields, generating controversy due to the variability in outcomes...
February 6, 2024: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/38295060/an-update-on-the-current-indications-for-in-vitro-maturation
#30
JOURNAL ARTICLE
Vu N-A Ho, Tuong M Ho, Lan N Vuong, Juan García-Velasco
PURPOSE OF REVIEW: In vitro maturation has become a significant component of modern assisted reproductive techniques. Published data have been supported for the safety and effectiveness of in vitro maturation treatment. In recent years, potential indications for in vitro maturation (IVM) have been a topic of interest and investigation. RECENT FINDINGS: Significant improvements in technique enhancement and data publication for evaluating the efficacy of IVM have been achieved...
February 1, 2024: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/38295043/ideal-frozen-embryo-transfer-regime
#31
JOURNAL ARTICLE
Juan Castillo, Shahar Kol
PURPOSE OF REVIEW: This review aims to compare evidence on four criteria (embryo implantation, obstetric outcomes, patient convenience, and IVF-unit efficiency) by analyzing published research on different endometrial preparation methods for frozen embryo transfer (FET). RECENT FINDINGS: While the artificial-FET cycle provides advantages in scheduling and implantation, it falls short in ensuring optimal obstetric outcomes. In contrast, natural-FET ensures embryo implantation conditions if ovulation is correctly identified...
February 1, 2024: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/38170553/the-treatment-of-endometriosis-associated-infertility-erratum
#32
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
February 1, 2024: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/38170552/updates-in-the-treatment-of-hr-her2-breast-cancer
#33
REVIEW
Nikita V Baclig, Kelly E McCann
PURPOSE OF REVIEW: Breast cancer (BC) is the most common cancer among women in the United States and the second leading cause of cancer death. BC research, diagnostics, drug development, and expansion of therapies for novel indications advances so rapidly that BC treatment standards change month-by-month. Herein we discuss notable advancements in the past year for hormone receptor positive (HR+) HER2 negative (HER2-) BC. RECENT FINDINGS: Radiolabeled estradiol imaging and circulating tumor DNA (ctDNA) have changed our approach to metastatic BC (mBC) detection...
February 1, 2024: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/38170551/new-strategies-for-the-management-of-triple-negative-breast-cancer
#34
REVIEW
Fauzia Riaz
PURPOSE OF REVIEW: This review highlights important changes in our understanding of triple-negative breast cancer. It highlights important novel approaches in treatment and reviews predicts potential challenges facing the treatment of triple-negative breast cancer. RECENT FINDINGS: There is a clear shift away from chemotherapy-centric approaches to the treatment of breast cancer, and instead, a move towards incorporating immune checkpoint inhibitors, antibody-drug conjugates, and other targeted therapies...
February 1, 2024: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/38170550/new-approaches-for-human-epidermal-growth-factor-receptor-2-low-and-human-epidermal-growth-factor-receptor-2-overexpressing-metastatic-breast-cancer
#35
REVIEW
Karissa Britten, Nicholas McAndrew
PURPOSE OF REVIEW: In recent years, there has been a flurry of activity in the human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer space. New, powerful drugs like trastuzumab deruxtecan have challenged our fundamental definition of what HER2 expression means as a predictive biomarker. RECENT FINDINGS: Recent approvals of multiple agents in the second line-metastatic setting have given patients access to a variety of new agents, but also raise questions with regard to optimal sequencing...
February 1, 2024: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/38170549/a-review-of-racial-disparities-in-ovarian-cancer-and-clinical-trials
#36
REVIEW
Maryam Ali, Krishnansu S Tewari
PURPOSE OF REVIEW: Ovarian cancer ranks fifth in mortality among women with cancer and accounts for more death compared to any other gynecological cancers. This review summarizes the most recent literature on disparities in ovarian cancer as well as within recent clinical trials. RECENT FINDINGS: Recent studies have identified a notable disparity in genetic testing utilization, disease stage at the time of diagnosis, and adherence to treatment guidelines between Black women and their White counterparts, ultimately leading to increased mortality rates among Black women from ovarian cancer...
February 1, 2024: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/38170548/maintenance-therapy-for-newly-and-recurrent-epithelial-ovarian-cancer-current-therapies-and-future-perspectives
#37
REVIEW
Vanda Salutari, Elena Giudice, Domenica Lorusso
PURPOSE OF REVIEW: Epithelial ovarian cancer (EOC) is the fifth cause of cancer death among women, and 70-80% of patients relapse within 2 years from the last cycle of first-line chemotherapy despite a complete response to chemotherapy and optimal debulking surgery. In this context, the goal of the maintenance treatment strategy is to prolong the time to recurrence. The recent development of targeted molecular therapies resulted in a broader spectrum of maintenance therapeutic options with consequent higher clinical benefit but less toxicity...
February 1, 2024: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/38170547/editorial-introduction
#38
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
February 1, 2024: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/37873756/a-review-of-the-state-of-cervical-cancer-updates-from-prevention-to-recurrent-disease
#39
REVIEW
Sarah M Crafton, Puja S Venkat, Ritu Salani
PURPOSE OF REVIEW: To summarize the recent updates in cervical cancer from prevention and early detection to the management of early stage and recurrent disease as well as future areas of exploration. RECENT FINDINGS: The importance of the human papilloma virus vaccine and screening continue to make an impact in reducing the global burden of cervical cancer. In early-stage, low risk disease, new studies have demonstrated the role of less radical surgery with similar disease related outcomes...
February 1, 2024: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/37792525/latest-advances-in-immuno-oncology-for-endometrial-cancer-single-agent-and-combination-regimens
#40
REVIEW
Michael Richardson, Dana M Chase
PURPOSE OF REVIEW: The scope of immuno-oncology in endometrial cancer has changed rapidly in the last several years, requiring up-to-date knowledge for those who treat these patients. RECENT FINDINGS: This article will focus on molecular profiling, recent trials, and FDA approvals of targeted immuno-oncology medications in endometrial cancer. These include immune checkpoint inhibitors alone or with combination treatment. SUMMARY: The publication of the TCGA has led to significant focus on molecular subgroupings into POLEm, MMRd, NSMP, and p53m groups...
February 1, 2024: Current Opinion in Obstetrics & Gynecology
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