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Journals Current Opinion in Obstetrics ...

Current Opinion in Obstetrics & Gynecology

https://read.qxmd.com/read/37387695/an-update-and-review-of-nontubal-ectopic-pregnancy-management
#21
REVIEW
Katherine Kostroun, Virginia-Arlene Go, Randal D Robinson
PURPOSE OF REVIEW: Nontubal ectopic pregnancies appear to be increasing in prevalence. Increasingly, minimally invasive methods for management are being utilized. A current literature review and recommendations for management of nontubal ectopic pregnancy is presented in this review. RECENT FINDINGS: Nontubal ectopic pregnancies are less common than tubal ectopic pregnancies but present a unique and significant threat to patient's health and are optimally managed by specialists familiar with the condition...
August 1, 2023: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/37387694/editorial-introductions
#22
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
August 1, 2023: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/37266579/vitamin-d-and-infertility
#23
REVIEW
Samantha Simpson, Lubna Pal
PURPOSE OF REVIEW: Vitamin D deficiency has been implicated as a contributing factor to a spectrum of reproductive health burden, including difficulty conceiving, pathogenesis of gynaecological disorders such as uterine fibroids and endometriosis, to metabolic and endocrine burden of polycystic ovarian syndrome (PCOS). RECENT FINDINGS: There have been recent publications showing that in infertile women who are supplemented with vitamin D, there are higher pregnancy rates; there are improved ovarian reserve parameters in women with diminished ovarian reserve; curtailed fibroid growth in those with uterine myomas; lessened dysmenorrhea in endometriosis patients; and improved menstrual regularity, lowered testosterone, AMH and insulin levels in women with PCOS...
August 1, 2023: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/37266575/diagnostic-and-surgical-approaches-to-congenital-uterine-anomalies-for-the-minimally-invasive-gynecologic-surgeon
#24
REVIEW
Colleen Murphy, Annemieke Wilcox, Alla Vash-Margita
PURPOSE OF REVIEW: Congenital uterine anomalies (CUAs) impact the physical and psychosocial wellbeing of affected patients. Managing these conditions depends on the clinical scenario, and in some cases, can involve the use of minimally invasive surgical techniques. The purpose of this review is to provide an update of the diagnosis, perioperative considerations, and treatment of CUAs. RECENT FINDINGS: The American Society for Reproductive Medicine (ASRM) updated the guidelines for classification of CUAs to provide practitioners with a standardized classification system and have created an interactive tool designed for provider use...
August 1, 2023: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/37144584/new-treatment-options-for-nonsurgical-management-of-uterine-fibroids
#25
REVIEW
SiWon Lee, Elizabeth A Stewart
PURPOSE OF REVIEW: Uterine fibroids is a common problem in reproductive-age individuals, frequently causing abnormal uterine bleeding, bulk symptoms, and adverse reproductive outcomes. Traditionally, almost half of the women with symptomatic fibroids received surgery for definitive treatment. There are a growing number of nonsurgical options for treatment that have become available for patients who desire conservative treatment or those with contraindications to surgery. RECENT FINDINGS: The introduction of oral gonadotropin-releasing hormone antagonists in combination with low-dose physiologic hormonal therapy demonstrated improvement in heavy menstrual bleeding, pain, and quality of life with preservation of bone density and a modest reduction in uterine volume with few hypogonadal side effects...
August 1, 2023: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/37144571/noninvasive-preimplantation-genetic-testing-using-the-embryo-spent-culture-medium-an-update
#26
REVIEW
Belen Lledo, Ruth Morales, Jose Antonio Ortiz, Andrea Bernabeu, Rafael Bernabeu
PURPOSE OF REVIEW: The presence of cell-free DNA (cf-DNA) in the embryo spent culture medium allows to develop a noninvasive PGT-A (niPGTA). Noninvasive PGT-A may provide a simpler, safer and less costly approach to preimplantation genetic testing of aneuploidy (PGT-A). Furthermore, niPGTA would provide wider access to embryo genetic analysis and circumvent many legal and ethical considerations. However, the concordance rate between the results obtained by PGT-A and niPGTA varies among studies and, their clinical utility has not been already demonstrated...
August 1, 2023: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/37696520/editorial-introductions
#27
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
June 1, 2023: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/37266679/the-minimally-invasive-approach-to-abdominal-cerclage-indications-complications-and-techniques-for-placement
#28
JOURNAL ARTICLE
Caitlin Waters, Gabriella Pinho, Sara Kim, Jennifer Blaber, Xun Lian
PURPOSE OF REVIEW: Laparoscopic abdominal cerclage placement has become the favored approach for management of refractory cervical insufficiency. There are special considerations with respect to surgical method, management of pregnancy loss, and delivery following placement. This review addresses current literature on transabdominal cerclage with a focus on up-to-date minimally invasive techniques. RECENT FINDINGS: Recent literature on abdominal cerclage has compared laparoscopic and open approaches, evaluated the effect of preconception placement on fertility, and explored the upper gestational limit for dilation and evacuation with an abdominal cerclage in situ...
June 1, 2023: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/37185354/how-effective-are-lifestyle-interventions-for-overweight-women-trying-to-conceive
#29
REVIEW
Roman Alexander Friedrich Hiller, Georg Griesinger
PURPOSE OF REVIEW: To summarize and critically review the current knowledge on the effectiveness of lifestyle modifications for overweight women trying to conceive. RECENT FINDINGS: Overweight is associated with a wide spectrum of disorders, which may directly or indirectly affect fertility [from menstrual cycle irregularities to a lower chance of live birth after assisted reproductive technology (ART) treatment]. Weight loss through nonpharmaceutical lifestyle interventions is achievable...
June 1, 2023: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/37185353/does-pgt-a-affect-cumulative-live-birth-rate
#30
REVIEW
Serin Seckin, Eric J Forman
PURPOSE OF REVIEW: Preimplantation genetic testing for the purpose of aneuploidy screening (PGT-A) has increased in use over the last decade. RECENT FINDINGS: Whether PGT-A benefits all of the patients that choose to employ it has been a concern, as recent studies have highlighted a potential decrease in cumulative live birth rate (CLBR) for younger patients undergoing embryo transfer. However, there are limitations to many of these studies and the intended benefit of PGT-A, which is to aid as a selection tool, thus increasing the live birth rate per transfer, must not be ignored...
June 1, 2023: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/37185352/the-future-of-frozen-thawed-embryo-transfer-in-hormone-replacement-therapy-cycles
#31
REVIEW
Kristine Løssl, Anne Lærke Spangmose, Louise Laub Asserhøj, Tine Vrist Dam, Anja Pinborg
PURPOSE OF REVIEW: This review focuses on the efficacy of letrozole stimulated frozen-thawed embryo transfer (FET) compared to hormone replacement therapy (HRT) FET in women with polycystic ovarian syndrome (PCOS) and/or oligo-anovulation. Further, obstetric and perinatal risks in HRT FET are summarized. RECENT FINDINGS: The presence of a corpus luteum seems to reduce the risk of pregnancy-related hypertension and preeclampsia after FET. As a natural cycle (NC) FET is not an option for women with oligo-/amenorrhea these women may benefit from FET with mild stimulation compared to HRT FET...
June 1, 2023: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/37185351/getting-closer-to-the-truth
#32
JOURNAL ARTICLE
Juan A Garcia-Velasco, Emre Seli
No abstract text is available yet for this article.
June 1, 2023: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/37185350/editorial-introductions
#33
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
June 1, 2023: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/36943690/the-importance-of-follicular-flushing-in-optimizing-oocyte-retrieval
#34
REVIEW
George Lainas, Tryfon Lainas, Efstratios Kolibianakis
PURPOSE OF REVIEW: To critically evaluate the use of follicular flushing during oocyte retrieval. RECENT FINDINGS: The latest meta-analysis evaluating follicular flushing does not favour its use over single aspiration. The randomized controlled trials (RCTs) included, however, are characterized by significant heterogeneity regarding the population analysed, the needle type and lumen used, the aspiration pressure applied and the number of flushing attempts performed...
June 1, 2023: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/36943683/treatment-options-for-molecular-subtypes-of-endometrial-cancer-in-2023
#35
REVIEW
Hannah C Karpel, Brian Slomovitz, Robert L Coleman, Bhavana Pothuri
PURPOSE OF REVIEW: This article reviews treatment strategies in endometrial cancer by molecular subtype. RECENT FINDINGS: The Cancer Genome Atlas (TCGA) classifies four molecular subtypes of endometrial cancer - mismatch repair-deficient (dMMR)/microsatellite instability-high (MSI-H), copy number high (CNH)/p53abn, copy number low (CNL)/no specific molecular profile (NSMP), and POLEmut - which are validated and highly prognostic. Treatment consideration by subtype is now recommended...
June 1, 2023: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/36912320/treatment-options-for-endometrial-hypoproliferation
#36
REVIEW
Yigit Cakiroglu, Bulent Tiras, Jason Franasiak, Emre Seli
PURPOSE OF REVIEW: Endometrial hypoproliferation refers to the failure of the endometrium to reach optimal thickness during fresh or frozen embryo transfer cycles in women undergoing infertility treatment with in-vitro fertilization (IVF). This review discusses the treatment options for endometrial hypoproliferation. RECENT FINDINGS: Apart from factors related to the embryo quality, ultrasonographic findings associated with the endometrium, such as endometrial thickness, endometrial pattern and subendometrial blood flow, are considered key factors associated with the outcome of assisted reproductive treatment...
June 1, 2023: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/37266690/the-genetic-background-of-female-reproductive-disorders-a-systematic-review
#37
JOURNAL ARTICLE
Triada Doulgeraki, Maria Papageorgopoulou, Stamatina Iliodromiti
PURPOSE OF REVIEW: Reproductive function is the interplay between environmental factors and the genetic footprint of each individual. The development in genetic analysis has strengthened its role in the investigation of female reproductive disorders, potential treatment options and provision of personalized care. Despite the increasing requirement of genetic testing, the evidence of the gene-disease relationships (GDR) is limited. We performed a systematic review exploring the associations between the most frequent female reproductive endocrine disorders associated with subfertility [including polycystic ovaries syndrome (PCOS), premature ovarian failure (POI) and hypogonadotropic hypogonadism] and their genetic background in order to summarize current knowledge...
May 30, 2023: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/37266701/pelvic-abscess-to-drain-or-not-to-drain
#38
JOURNAL ARTICLE
Sophie Michelle Strong, Stylianos Michail Lazanakis, Elizabeth Ball
PURPOSE OF REVIEW: Pelvic abscess is a common gynaecological condition, particularly during and after the Covid-19 pandemic, possibly resulting from obstacles to accessing care during this time. To date, no consensus guideline on management exists with a lack of applicable randomized controlled trials (RCTs) comparing medical management with antibiotics alone, image-guided drainage and surgical management, despite this being a potentially life-threatening condition. RECENT FINDINGS: We present the current literature assessing risks, which contribute to failure of medical therapy, predictive models to guide management and reports of long-term sequelae...
May 29, 2023: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/37266568/take-it-or-leave-it-oophorectomy-at-the-time-of-benign-hysterectomy
#39
JOURNAL ARTICLE
Hilary R Haber, Hannah M French, Peter R Movilla, Keith B Isaacson, Stephanie N Morris
PURPOSE OF REVIEW: Previous modeling data suggest ovarian conservation up to age 65 for women without adnexal disease and at average risk of ovarian cancer because of an increase in mortality associated with ovarian removal. Recent modeling data challenges this practice. This review of recent literature will update providers regarding consideration for oophorectomy at time of benign hysterectomy. RECENT FINDINGS: Oophorectomy at time of hysterectomy for women less than 50 years with estrogen supplementation and greater than 50 years without estrogen supplementation is not associated with increased mortality...
May 29, 2023: Current Opinion in Obstetrics & Gynecology
https://read.qxmd.com/read/37266567/the-impact-of-the-dobbs-decision-on-in-vitro-fertilization-and-fertility-care
#40
JOURNAL ARTICLE
Ashley Ulker, M Blake Evans, LaTasha B Craig
PURPOSE OF REVIEW: The 2022 Supreme Court ruling in Dobbs vs Jackson marks a frightening new reality in America. Physicians and patients have been left confused and concerned regarding the broader implications of this ruling. Now that the constitutional right to an abortion has been overturned and the power has been relinquished to individual states, there is justifiable concern regarding the impact on in-vitro fertilization (IVF). This review explores the ways IVF and fertility care are at risk in the context of our new reality...
May 24, 2023: Current Opinion in Obstetrics & Gynecology
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