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Clinical Oncology: a Journal of the Royal College of Radiologists

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https://read.qxmd.com/read/30782445/incidental-dose-to-ipsilateral-and-contralateral-internal-mammary-chain-by-partial-tangential-arc-technique-a-single-institutional-analysis-in-breast-cancer-patients
#1
LETTER
A Munshi, S Agrawal, B Sarkar, T Ganesh, B K Mohanti
No abstract text is available yet for this article.
February 16, 2019: Clinical Oncology: a Journal of the Royal College of Radiologists
https://read.qxmd.com/read/30744934/can-we-discharge-dynamically-risk-stratified-low-risk-excellent-response-to-treatment-thyroid-cancer-patients-after-5-years-of-follow-up
#2
K Seejore, G E Gerrard, V M Gill, R D Murray
AIMS: The 2014 British Thyroid Association thyroid cancer guidelines recommend lifelong follow-up of thyroid cancer patients. This is probably unnecessary, can cause patient anxiety, is time consuming and places significant demand on National Health Service resources. It has been suggested that low-risk differentiated thyroid cancer (DTC) patients could be discharged to primary care once they are 5 years from diagnosis and treatment. The aim of this study was to investigate the potential safety of this practice...
February 7, 2019: Clinical Oncology: a Journal of the Royal College of Radiologists
https://read.qxmd.com/read/30744933/serum-biomarkers-as-prognostic-factors-for-metastatic-sarcoma
#3
N Aggerholm-Pedersen, K Maretty-Kongstad, J Keller, A Safwat
AIMS: To investigate the prognostic value of combining inflammatory biomarkers in a prognostic index (Aarhus composite biomarker score: ACBS), adjusted for known confounders, including comorbidity, in patients with metastatic sarcoma. MATERIALS AND METHODS: All patients diagnosed with metastatic sarcoma from 1993 until 2008 were extracted from the Aarhus sarcoma database. The levels of serum albumin, C-reactive protein, serum sodium, haemoglobin, neutrophils and lymphocytes were collected...
February 7, 2019: Clinical Oncology: a Journal of the Royal College of Radiologists
https://read.qxmd.com/read/30738715/cutaneous-angiosarcoma-secondary-to-lymphoedema-or-radiation-therapy-a-systematic-review
#4
M Co, A Lee, A Kwong
AIMS: Secondary angiosarcoma is known to be associated with lymphoedema or radiation after cancer treatment. This systematic review aims to evaluate the clinical features and outcomes of secondary angiosarcoma commonly arising after breast cancer treatment. MATERIALS AND METHODS: A systematic review was carried out according to the PRISMA protocol. Medline, EMBASE, CINAHL and Cochrane databases were searched for English articles to April 2018 with predefined strategy...
February 6, 2019: Clinical Oncology: a Journal of the Royal College of Radiologists
https://read.qxmd.com/read/30737068/hypofractionated-radiotherapy-in-oesophageal-cancer-for-patients-unfit-for-systemic-therapy-a-retrospective-single-centre-analysis
#5
C M Jones, K Spencer, C Hitchen, T Pelly, B Wood, P Hatfield, A Crellin, D Sebag-Montefiore, R Goody, T Crosby, G Radhakrishna
AIMS: Chemoradiotherapy (CRT) is established as a superior treatment option to definitive radiotherapy in the non-surgical management of oesophageal cancer. For patients precluded from CRT through choice or comorbidity there is little evidence to guide delivery of single-modality radiotherapy. In this study we outline outcomes for patients unfit for CRT who received a hypofractionated radiotherapy (HRT) regimen. MATERIALS AND METHODS: A retrospective UK single-centre analysis of 61 consecutive patients with lower- or middle-third adenocarcinoma (OAC; 61%) or squamous cell carcinoma of the oesophagus managed using HRT with radical intent between April 2009 and 2014...
February 5, 2019: Clinical Oncology: a Journal of the Royal College of Radiologists
https://read.qxmd.com/read/30718089/endometrial-carcinoma-follow-up-time-for-a-change
#6
LETTER
H Saxby, A Tailor, S Essapen
No abstract text is available yet for this article.
February 1, 2019: Clinical Oncology: a Journal of the Royal College of Radiologists
https://read.qxmd.com/read/30718088/interim-18-f-fdg-positron-emission-tomography-computed-tomography-during-chemoradiotherapy-in-the-management-of-cancer-patients
#7
LETTER
C Garibaldi, M Ferrari, C M Grana, B A Jereczek-Fossa, M Cremonesi
No abstract text is available yet for this article.
February 1, 2019: Clinical Oncology: a Journal of the Royal College of Radiologists
https://read.qxmd.com/read/30718087/moderately-hypofractionated-radiotherapy-in-node-positive-prostate-cancer
#8
I Mallick, A Das, M Arunsingh
AIMS: Node-positive prostate cancer is a unique subgroup, with varied practice on locoregional treatment. Definitive treatment with hypofractionated radiotherapy has not been widely reported. We have routinely used standard regimens of hypofractionated radiotherapy for node-positive disease and report our results of toxicity, biochemical control and survival. MATERIALS AND METHODS: Medical records of patients diagnosed with prostate cancer between February 2011 and April 2016 with radiologically involved pelvic nodes on magnetic resonance imaging/computed tomography without distant metastases were analysed...
February 1, 2019: Clinical Oncology: a Journal of the Royal College of Radiologists
https://read.qxmd.com/read/30718086/clinical-outcomes-and-prognostic-features-of-angiosarcoma-significance-of-prior-radiation-therapy
#9
E Merfeld, P Gabani, M B Spraker, I Zoberi, H Kim, B Van Tine, J Chrisinger, J M Michalski
AIMS: Angiosarcoma is a rare and aggressive malignancy with a poor prognosis. There is limited literature describing prognostic factors and guidelines for treatment. We aim to describe outcomes in angiosarcoma, including the impact of patient-, tumour- and treatment-related factors on prognosis. MATERIALS AND METHODS: Patients with non-metastatic angiosarcoma diagnosed between 2008 and 2017 were retrospectively reviewed. Univariable and multivariable Cox proportional hazards methods were used to evaluate factors associated with locoregional recurrence, distant failure and overall survival...
February 1, 2019: Clinical Oncology: a Journal of the Royal College of Radiologists
https://read.qxmd.com/read/30683489/-indeed-cure-is-not-enough-a-reflection-on-paediatric-radiation-oncology
#10
EDITORIAL
T Ajithkumar, R D Kortmann
No abstract text is available yet for this article.
January 22, 2019: Clinical Oncology: a Journal of the Royal College of Radiologists
https://read.qxmd.com/read/30670336/pediatric-normal-tissue-effects-in-the-clinic-pentec-an-international-collaboration-to-analyse-normal-tissue-radiation-dose-volume-response-relationships-for-paediatric-cancer-patients
#11
L S Constine, C M Ronckers, C-H Hua, A Olch, L C M Kremer, A Jackson, S M Bentzen
With advances in multimodality therapy, childhood cancer cure rates approach 80%. However, both radiotherapy and chemotherapy can cause debilitating or even fatal late adverse events that are critical to understand, mitigate or prevent. QUANTEC (Quantitative Analysis of Normal Tissue Effects in the Clinic) identified radiation dose constraints for normal tissues in adults and pointed out the uncertainties in those constraints. The range of adverse events seen in children is different from that in adults, in part due to the vulnerability/characteristics of radiation damage to developing tissues, and in part due to the typical body sites affected by childhood cancer that lead to collateral irradiation of somewhat different normal tissues and organs compared with adults...
January 19, 2019: Clinical Oncology: a Journal of the Royal College of Radiologists
https://read.qxmd.com/read/30655168/radiotherapy-advances-in-paediatric-medulloblastoma-treatment
#12
L Padovani, G Horan, T Ajithkumar
Radiotherapy is an essential element in the multidisciplinary management of children with medulloblastoma and postoperative craniospinal axis radiotherapy is considered to be the cornerstone of curative treatment. With modern multidisciplinary management, more than 80% of children with standard-risk medulloblastoma and up to 70% of children with high-risk medulloblastoma are long-term survivors. Current clinical trials are evaluating risk-adapted radiotherapy in standard-risk medulloblastoma to reduce long-term sequelae, whereas the research approach in high-risk medulloblastoma is to improve clinical outcome with dose-intensification of chemotherapy and the use of hyperfractionated radiotherapy regimens...
January 14, 2019: Clinical Oncology: a Journal of the Royal College of Radiologists
https://read.qxmd.com/read/30639254/evolving-radiotherapy-techniques-in-paediatric-oncology
#13
T Steinmeier, S Schulze Schleithoff, B Timmermann
AIMS: Childhood cancer is rare and survival of childhood cancer has increased up to 80% at 5 years after diagnosis. Radiotherapy is an important element of the multimodal treatment concept. However, due to growing tissue, children are particularly sensitive to radiation-related side-effects and the induction of secondary malignancies. However, radiotherapy techniques have continuously progressed. In addition, modern treatment concepts have been improved in order to minimise long-term effects...
January 10, 2019: Clinical Oncology: a Journal of the Royal College of Radiologists
https://read.qxmd.com/read/30616927/management-of-ependymoma-in-children-adolescents-and-young-adults
#14
N Thorp, L Gandola
Paediatric ependymomas are rare, malignant tumours arising throughout the central nervous system, but most frequently (in children) the posterior fossa. The standard of care for localised disease is gross total resection and focal radiotherapy, resulting in overall survival rates of up to 85%. Despite improvements in survival, treatment remains challenging, with persistently high rates of (rarely curable) relapse alongside risks of significant tumour and treatment-related toxicity. Systemic therapy is currently used to delay radiotherapy in very young children and in the management of metastatic or recurrent disease...
January 4, 2019: Clinical Oncology: a Journal of the Royal College of Radiologists
https://read.qxmd.com/read/30600192/simultaneous-integrated-boost-improving-the-patient-journey-during-breast-cancer-radiotherapy-safely
#15
LETTER
S Chatterjee, A Mahata, S Mandal, S Chakraborty
No abstract text is available yet for this article.
December 29, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://read.qxmd.com/read/30594342/good-practice-guide-for-paediatric-radiotherapy
#16
EDITORIAL
M N Gaze
No abstract text is available yet for this article.
December 26, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://read.qxmd.com/read/30594341/survival-outcomes-from-concurrent-chemoradiation-for-lung-cancer-in-indian-patients-are-comparable-with-reported-uk-outcomes
#17
LETTER
M Arunsingh, R K Shrimali, S Chakraborty, B Arun, S Prasath, S Chatterjee
No abstract text is available yet for this article.
December 26, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://read.qxmd.com/read/30583927/is-there-a-role-for-an-18f-fluorodeoxyglucose-derived-biological-boost-in-squamous-cell-anal-cancer
#18
A Sabbagh, C Jacobs, R Cooke, K-Y Chu, S M Ng, V Y Strauss, P S Virdee, M A Hawkins, M C Aznar, R Muirhead
AIMS: To investigate the potential role for a biological boost in anal cancer by assessing whether subvolumes of high 18F-fluorodeoxyglucose (FDG) avidity, identified at outset, are spatially consistent during a course of chemoradiotherapy (CRT). MATERIALS AND METHODS: FDG-positron emission tomography (FDG-PET) scans from 21 patients enrolled into the ART study (NCT02145416) were retrospectively analysed. In total, 29 volumes including both primary tumours and involved nodes >2 cm were identified...
December 21, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://read.qxmd.com/read/30580905/a-psychosexual-rehabilitation-booklet-increases-vaginal-dilator-adherence-and-knowledge-in-women-undergoing-pelvic-radiation-therapy-for-gynaecological-or-anorectal-cancer-a-randomised-controlled-trial
#19
F P Lubotzky, P Butow, C Hunt, D S J Costa, R Laidsaar-Powell, S Carroll, S R Thompson, M Jackson, A Tewari, K Nattress, I Juraskova
AIMS: Women treated with pelvic radiation therapy (PRT) for gynaecological or anorectal cancer report a high number of sexual problems and unmet post-treatment psychosexual information needs. Currently, there is suboptimal adherence to recommended rehabilitation aids, such as vaginal dilators, and a paucity of resources to facilitate post-radiation rehabilitation and reduce distress in this population. This randomised controlled trial aimed to evaluate the effectiveness of a study-developed psychosexual rehabilitation booklet in this setting...
December 20, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://read.qxmd.com/read/30553580/accuracy-of-response-assessment-positron-emission-tomography-computed-tomography-following-definitive-radiotherapy-without-chemotherapy-for-head-and-neck-squamous-cell-carcinoma
#20
M Arunsingh, S Vaidyanathan, K E Dyker, M Sen, A F Scarsbrook, R J D Prestwich
AIM: There are few data to inform on the use of response assessment 2-[fluorine-18]-fluoro-2-deoxy-d-glucose (FDG) positron emission tomography-computed tomography (PET-CT) following radical radiotherapy without chemotherapy for head and neck squamous cell carcinoma (HNSCC). This retrospective study evaluated the accuracy of PET-CT in HNSCC following radical radiotherapy. MATERIALS AND METHODS: In total, 138 patients with HNSCC treated with radical radiotherapy without chemotherapy who underwent a baseline and response assessment FDG PET-CT were identified...
December 12, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
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