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Journals European Journal of Gastroente...

European Journal of Gastroenterology & Hepatology

https://read.qxmd.com/read/38874917/cardiovascular-complications-during-delivery-hospitalizations-in-patients-with-nonalcoholic-fatty-liver-disease-in-pregnancy
#21
JOURNAL ARTICLE
Chengu Niu, Jing Zhang, Nida Khalid, Kaiwen Zhu, Tausif Syed, Hongli Liu, Patrick I Okolo
OBJECTIVE: While the association between metabolic dysfunction-associated steatotic liver disease (MASLD) and long-term cardiovascular risks has been studied, the impact of MASLD on cardiovascular events during delivery hospitalizations remains relatively unexplored. This study aims to examine the prevalence of cardiovascular diseases (CVDs) and cardiac arrhythmias in pregnant patients with MASLD and identify potential risk factors. METHODS: A retrospective analysis of hospital discharge records from the National Inpatient Sample database between 2009 and 2019 was conducted to assess maternal cardiovascular outcomes...
June 6, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/38829959/clinicopathological-features-prognostic-factors-and-prognostic-survival-prediction-in-patients-with-extrahepatic-bile-duct-cancer-liver-metastasis
#22
JOURNAL ARTICLE
Xianyu Huang, Wenhui Chen, Jiaxin Liu, Yonghui Liao, Jia Cai, Dingwen Zhong
PURPOSE: Extrahepatic bile duct cancer (EBDC) is a compound malignant tumor mainly consisting of extrahepatic cholangiocarcinoma and gallbladder carcinoma. Most EBDC patients are diagnosed at an advanced stage characterized by distant metastases, and the liver is one of the common sites of metastasis. Hence, the purpose of this study is to investigate the clinicopathological features, identify prognostic risk factors, and assess the long-term prognosis of extrahepatic bile duct cancer liver metastasis (EBDCLM)...
May 31, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/38829950/metabolic-dysfunction-associated-steatotic-liver-disease-related-cirrhosis-and-incidence-of-portal-vein-thrombosis
#23
JOURNAL ARTICLE
Waseem Amjad, Zhenghui G Jiang, Michelle Lai
BACKGROUND: There is heterogeneous data on whether metabolic-associated steatohepatitis is an independent risk factor for portal vein thrombosis (PVT). We aim to compare the incidence of PVT in patients with cirrhosis with and without metabolic dysfunction-associated steatotic liver disease (MASLD). METHODS: This is a single-center retrospective study of patients with cirrhosis seen between 1 January 2016 and 31 January 2021. Patients with a history of hepatocellular cancer, liver transplant, Budd-Chiari syndrome, and intra-abdominal malignancies were excluded...
May 31, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/38829956/the-second-irish-helicobacter-pylori-working-group-consensus-for-the-diagnosis-and-treatment-of-helicobacter-pylori-infection-in-adult-patients-in-ireland
#24
JOURNAL ARTICLE
Sinéad M Smith, Breida Boyle, Martin Buckley, Conor Costigan, Maeve Doyle, Richard Farrell, M Syafiq Ismail, David Kevans, Sean Nugent, Anthony O'Connor, Colm O'Morain, Vikrant Parihar, Cristín Ryan, Deirdre McNamara
BACKGROUND: There has been an increase in resistance to many of the antimicrobials used to treat Helicobacter pylori (H. pylori) nationally and internationally. Primary clarithromycin resistance and dual clarithromycin and metronidazole resistance are high in Ireland. These trends call for an evaluation of best-practice management strategies. OBJECTIVE: The objective of this study was to revise the recommendations for the management of H. pylori infection in adult patients in the Irish healthcare setting...
May 30, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/38829948/the-impact-of-meld-exception-points-for-hydrothorax-on-posttransplant-mortality-a-propensity-score-matched-analysis
#25
JOURNAL ARTICLE
Sawsan Fathma, Sarpong Boateng, Ayesha Amatya, Prince Ameyaw, Bubu A Banini
BACKGROUND: Hepatic hydrothorax is a challenging complication of end-stage liver disease, and.patients with this complication can receive model for end-stage liver disease (MELD) exception points if they meet specific criteria as defined by United Network for Organ Sharing (UNOS). This research aimed to analyze the effect of receiving MELD exception points for hepatic hydrothorax on posttransplant mortality, using a national transplant database. METHODS: Patients >18 years in the UNOS database awaiting liver transplant between 2012 and 2023 were identified based on their petition for MELD exception points...
May 30, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/38808872/sarcopenia-is-an-independent-risk-factor-for-short-term-mortality-in-patients-undergoing-transjugular-intrahepatic-portosystemic-shunt
#26
JOURNAL ARTICLE
Elina Stoffel, Soo Young Hwang, Xia Qian, Brian Geller, Giuseppe Morelli, Wei Zhang
BACKGROUND: Sarcopenia is common in patients with cirrhosis and is a risk factor for increased mortality. Transjugular intrahepatic portosystemic shunt (TIPS) placement has been utilized in cirrhosis patients with decompensation. We investigated the role of sarcopenia in predicting mortality in patients undergoing TIPS. METHODS: We conducted a single-center retrospective study of 232 patients with cirrhosis who underwent TIPS between January 2010 and December 2015...
May 27, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/38652516/nomogram-predicting-survival-in-patients-with-lymph-node-negative-hepatocellular-carcinoma-based-on-the-seer-database-and-external-validation
#27
JOURNAL ARTICLE
Ziqiang Li, Qingyong Hong, Kun Li
BACKGROUND: The relationship between lymph node (LN) status and survival outcome in hepatocellular carcinoma (HCC) is a highly controversial topic. The aim of this study was to investigate the prognostic factors in patients without LN metastasis (LNM) and to construct a nomogram to predict cancer-specific survival (CSS) in this group of patients. METHODS: We screened 6840 eligible HCC patients in the Surveillance, Epidemiology and End Results(SEER)database between 2010 and 2019 and randomized them into a training cohort and an internal validation cohort, and recruited 160 patients from Zhongnan Hospital of Wuhan University as an external validation cohort...
April 24, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/38652529/the-cost-implications-of-wilson-disease-among-hospitalized-patients-analysis-of-usa-hospitals
#28
JOURNAL ARTICLE
David Uihwan Lee, Ashton Harmacinski, Aneesh Bahadur, Ki Jung Lee, Hannah Chou, Mohammed Rifat Shaik, Harrison Chou, Gregory Hongyuan Fan, Jean Kwon, Reid Ponder, Kevin Chang, KeeSeok Lee, Zurabi Lominadze
BACKGROUND AND AIM: In this study, we used a national cohort of patients with Wilson's disease (WD) to investigate the admissions, mortality rates, and costs over the captured period to assess specific subpopulations at higher burden. METHODS: Patients with WD were selected using 2016-2019 National Inpatient Sample (NIS). The weighted estimates and patient data were stratified using demographics and medical characteristics. Regression curves were graphed to derive goodness-of-fit for each trend from which R2 and P values were calculated...
April 23, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/38652524/intestinal-ultrasound-scan-predicts-corticosteroid-failure-and-colectomy-risk-in-patients-with-ulcerative-colitis
#29
JOURNAL ARTICLE
Baisi Yuan, Pengfei Huang, Miaofang Yang, Guoxing Tang, Fangyu Wang
OBJECTIVE: Intestinal ultrasound (IUS) is an emerging modality for assessing disease activity, extent, and treatment response in ulcerative colitis. This study aimed to evaluate the potential of IUS in predicting severe flares, the need for rescue therapy (corticosteroid failure), and colectomy in patients with ulcerative colitis. METHODS: We conducted a retrospective review of medical records, collecting clinical and IUS data. The Milan Ultrasound Criteria (MUC) score was used to assess ulcerative colitis severity...
April 17, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/38652507/association-between-nonalcoholic-fatty-liver-disease-and-gallstone-risk-in-nonobese-and-lean-individuals
#30
JOURNAL ARTICLE
Nam Hee Kim, Ji Hun Kang, Hong Joo Kim
PURPOSE: The association between nonobese/lean nonalcoholic fatty liver disease (NAFLD) and gallstone formation remains unclear. We aimed to assess whether NAFLD is an independent risk factor for gallstones, even in nonobese or lean individuals. METHODS: We analyzed 265 353 asymptomatic adults who underwent abdominal ultrasonography. The risk of gallstone was assessed on the basis of obesity and NAFLD status. RESULTS: The overall prevalence rates of NAFLD and gallstones were 27...
April 17, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/38625821/appraisal-of-a-newly-developed-albi-sarcopenia-score-as-a-prognostic-marker-in-patients-with-hepatocellular-carcinoma
#31
JOURNAL ARTICLE
Maha Elsabaawy, Hanaa Badran, Amr Ragab, Rasha Abdelwahab, Eman Sayed, Sameh Afify, Warda Othman
OBJECTIVE: This study aimed to evaluate the impact of the combined Albumin-bilirubin (ALBI)/sarcopenia score as a newly developed prognostic model for hepatocellular carcinoma (HCC), with a focus on its utility in predicting mortality. METHODS: This prospective study was conducted on HCC patients who were followed for 1 year or until death. Sarcopenia was assessed radiologically by computed tomography at the level of L3. The study consisted of two sets: a development set in which the new ALBI-sarcopenia score was created, comprising 262 HCC patients, followed by an internal validation set with 100 patients...
April 17, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/38973543/impacts-of-rifaximin-and-midodrine-on-morbidity-mortality-and-quality-of-life-in-patients-with-decompensated-liver-cirrhosis
#32
RANDOMIZED CONTROLLED TRIAL
Maha Mohammad Elsabaawy, Medhat Assem, Hanaa Badran, Asmaa Mahmoud, Dalia Elsabaawy, Amr Ragab
BACKGROUND: Vasodilatation and bacterial dislocation are the main contributors to the catastrophic events in patients with decompensated liver cirrhosis (DLC). AIM: The aim of this study was to evaluate the impacts of adding midodrine and rifaximin on morbidity, mortality, and quality of life in patients with DLC. METHODS: This interventional clinical study included 100 consecutively enrolled DLC patients randomized 1 : 1 into two groups...
August 1, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/38973542/assessing-seasonal-variations-of-biomarkers-in-inflammatory-bowel-disease
#33
JOURNAL ARTICLE
Lidia Neamți, Tudor Catalin Drugan, Cristina Drugan, Ciprian Silaghi, Lidia Ciobanu, Tamás Ilyés, Alexandra Crăciun
OBJECTIVE: Inflammatory bowel diseases are chronic pathologies characterized by a complex interplay of genetic and environmental factors, as well as aberrant immune responses. This study aimed to investigate inflammation markers' seasonality and association with disease exacerbation episodes in patients with Crohn's disease and ulcerative colitis. METHODS: 284 patients were classified based on clinical, endoscopic, and histopathological criteria. Systemic inflammation was evaluated using C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and chitotriosidase, while fecal calprotectin was measured to assess intestinal inflammation...
August 1, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/38973541/symptoms-of-functional-dyspepsia-and-irritable-bowel-syndrome-among-medical-students-in-slovakia-and-their-relation-to-diet-and-exercise
#34
MULTICENTER STUDY
Peter Liptak, Martin Duricek, Martin Schnierer, Ivana Liptak Ziaciková, Robert Rosolanka, Eva Baranovicova, Igor Sturdik, Peter Jackuliak, Eduard Veseliny, Alena Varady, Peter Banovcin
INTRODUCTION: There is a substantial lack of data regarding the prevalence of irritable bowel syndrome (IBS) and functional dyspepsia (FD) in the region of Central/Eastern Europe. It is a well-described and known fact that environmental, ethnic, dietary, and cultural factors can influence the reporting of symptoms. Therefore, we aim to provide the first data documenting the prevalence of specific disorders of gut-brain interaction in Slovakia. METHODS: This is a multicenter-based study...
August 1, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/38829946/coexistence-of-metabolic-associated-fatty-liver-disease-and-autoimmune-or-toxic-liver-disease
#35
JOURNAL ARTICLE
Oscar Danielsson, Tiina Vesterinen, Johanna Arola, Fredrik Åberg, Markku J Nissinen
Fatty liver disease (FLD) affects approximately 25% of global adult population. Metabolic-associated fatty liver disease (MAFLD) is a term used to emphasize components of metabolic syndrome in FLD. MAFLD does not exclude coexistence of other liver disease, but impact of coexisting MAFLD is unclear. We investigated prevalence and characteristics of MAFLD in patients with biopsy-proven autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC), or toxic liver disease. Liver histopathology and clinical data from Helsinki University Hospital district (1...
July 1, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/38829945/hematological-ratios-in-patients-with-acute-decompensation-and-acute-on-chronic-liver-failure-prognostic-factors
#36
JOURNAL ARTICLE
Sameh A Lashen, Perihan Salem, Esraa Ibrahim, Dalia Abd Elmoaty, Walid I Yousif
BACKGROUND AND AIMS: Acute-on-chronic liver failure (ACLF) is the most severe form of acutely decompensated cirrhosis and is characterized by the presence of intense systemic inflammation. Leucocyte quantification can serve as an indirect indicator of systemic inflammation. In our study, we investigated the predictive value of hematological ratios (neutrophils to lymphocytes, monocyte to lymphocytes, platelets to lymphocytes, lymphocytes to C-reactive protein, and neutrophils to lymphocytes and platelets) in acute decompensation (AD) and ACLF patients and their relation to disease severity and early mortality...
July 1, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/38829944/development-and-validation-of-risk-prediction-model-for-bacterial-infections-in-acute-liver-failure-patients
#37
JOURNAL ARTICLE
Huimin Liu, Xiaoli Xie, Yan Wang, Xiaoting Wang, Xiaoxu Jin, Xiaolin Zhang, Yameng Wang, Zongyi Zhu, Wei Qi, Huiqing Jiang
Infections significantly increase mortality in acute liver failure (ALF) patients, and there are no risk prediction models for early diagnosis and treatment of infections in ALF patients. This study aims to develop a risk prediction model for bacterial infections in ALF patients to guide rational antibiotic therapy. The data of ALF patients admitted to the Second Hospital of Hebei Medical University in China from January 2017 to January 2022 were retrospectively analyzed for training and internal validation...
July 1, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/38829943/short-chain-fatty-acid-levels-in-stools-of-patients-with-inflammatory-bowel-disease-are-lower-than-those-in-healthy-subjects
#38
JOURNAL ARTICLE
Ozlem Ozturk, Gurkan Celebi, Umut Goktan Duman, Erhan Kupcuk, Metin Uyanik, Erdim Sertoglu
OBJECTIVE: Short-chain fatty acids (SCFAs) are produced when the microbiota in the large intestine cause fermentation of dietary carbohydrates and fibers. These fatty acids constitute the primary energy source of colon mucosa cells and have a protective effect in patients suffering from inflammatory bowel disease (IBD). This study aimed to compare the SCFA levels in the stools of patients with IBD and healthy controls. METHOD: Healthy controls and patients with IBD aged 18 and over were included in the study...
July 1, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/38829942/application-of-small-bowel-capsule-endoscopy-in-children-with-meckel-s-diverticulum
#39
JOURNAL ARTICLE
Lin Li, Xue Zhan, Yuxia Chen, Jun Li, Yuting Wang
BACKGROUND: Meckel diverticulum (MD) is an important cause of gastrointestinal bleeding in children. Small bowel capsule endoscopy (SBCE) is a first-line examination method applied to patients with obscure gastrointestinal bleeding, but there are few studies on its application in children with MD. This article aims to provide evidence in favor of the auxiliary diagnosis of MD in children by analyzing its characteristics using SBCE. METHODS: We retrospectively collected the clinical data of patients with suspected MD...
July 1, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/38829941/proton-pump-inhibitors-are-not-associated-with-fundic-gland-polyps-a-systematic-review-that-takes-into-consideration-all-known-confounders
#40
JOURNAL ARTICLE
Shiu Kum Lam, George Ka Kit Lau
Sporadic fundic gland polyps (FGPs) progress, albeit rarely, to dysplasia and cancer. Two meta-analyses, including 8 and 11 studies, concluded that proton pump inhibitors (PPIs) were associated with FGPs. Intervention is considered unnecessary when FGPs have a background of PPIs use. Both meta-analyses, however, disregarded known confounders: age, sex, endoscopy indications, study design (prospective or retrospective), duration of PPI use, and H. pylori infection. Confounders are known to invalidate meta-analyses...
July 1, 2024: European Journal of Gastroenterology & Hepatology
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