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Journals European Journal of Gastroente...

European Journal of Gastroenterology & Hepatology

https://read.qxmd.com/read/39373637/frequency-of-hepatitis-d-virus-with-different-hepatitis-b-virus-serological-markers-and-coinfections-in-hospital-patients-from-argentina-synchronous-testing-of-anti-hdv-antibodies-and-hdv-rna
#1
JOURNAL ARTICLE
Marianela Giorgio, Kelly Alejandra Ramírez Ladino, Guido López, Maricel Sosa Rojas, Estela Outon, Cecilia María Delfino
BACKGROUND: Hepatitis D virus (HDV) RNA-positive cases with total anti-HDV antibodies nonreactive were documented. Moreover, HDV infection was observed in subjects with occult hepatitis B virus infection. The prevalence of HDV infection in Argentina is low; however, further research in different populations is needed. OBJECTIVE: This study aimed to perform synchronous HDV detection in reactive hepatitis B virus patients treated in a public hospital in the province of Buenos Aires, Argentina, some of whom were coinfected with hepatitis C virus and/or HIV...
October 8, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/39373626/optic-nerve-sheath-diameters-predict-mortality-and-severity-in-hepatic-encephalopathy
#2
JOURNAL ARTICLE
Cumali Kus, Selen Acehan, Salim Satar, Muge Gulen, Sarper Sevdimbas, Ali İlker Akdoganlar, Mehmet Gorur
OBJECTIVE: The aim of this study was to compare the predictive power of optic nerve sheath diameter (ONSD) measured by brain computed tomography (CT) in patients diagnosed with hepatic encephalopathy (HE) in the emergency department, with other factors for mortality and disease severity. MATERIALS AND METHODS: A total of 217 patients aged 18 years and older with acute decompensation of cirrhosis diagnosed with HE in the emergency department were included in the study...
October 1, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/39373628/interaction-between-trouble-sleeping-and-diabetes-on-metabolic-dysfunction-associated-fatty-liver-disease-and-liver-fibrosis-in-adults-results-from-the-national-health-and-nutrition-examination-survey-2017-2018
#3
JOURNAL ARTICLE
Cui Zhang, Lili Cao, Bo Xu, Wei Zhang
BACKGROUND: Metabolic dysfunction-associated fatty liver disease (MAFLD), trouble sleeping, and diabetes, as major public health problems, were closely related. The study examined the interaction between trouble sleeping and diabetes on MAFLD and liver fibrosis in adults with MAFLD. METHODS: The data were obtained from the National Health and Nutrition Examination Survey 2017-2018. Multivariate logistic regression model and subgroup analyses were conducted to assess the relationship between either trouble sleeping or diabetes on MAFLD and liver fibrosis...
September 27, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/39324897/hyperthyroidism-and-hypothyroidism-in-patients-with-autoimmune-pancreatitis
#4
JOURNAL ARTICLE
Kenji Hirano, Katsuyuki Sanga, Hisayoshi Natomi, Kazuhiro Niwa
OBJECTIVE: The objective of this study is to clarify the clinical features of thyroid dysfunction observed in patients with autoimmune pancreatitis (AIP). METHODS: We repeatedly examined thyroid function in 74 patients with type 1 AIP (58 males, 16 females; average onset age of AIP 67 years). Clinical and serological findings in patients with thyroid dysfunction were analyzed. RESULTS: During follow-up, clinical and subclinical hypothyroidism were observed in 3 and 17 patients, respectively...
September 26, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/39324945/pregnancy-outcomes-in-greek-women-with-inflammatory-bowel-disease-a-longitudinal-national-retrospective-study
#5
JOURNAL ARTICLE
Evgenia Papathanasiou, Georgios Kokkotis, Georgios Axiaris, Georgia Bellou, Konstantina Chalakatevaki, Angeliki Christidou, Dimitrios K Christodoulou, Kalliopi Foteinogiannopoulou, Anthia Gatopoulou, Olga Giouleme, Konstantinos Gkoumas, Maria Κalogirou, Pantelis Karatzas, Konstantinos Κarmiris, Konstantinos Κatsanos, Anastasia Κourikou, Ioannis E Κoutroubakis, Christos Liatsos, Gerassimos J Mantzaris, Nicoletta Μathou, George Michalopoulos, Aikaterini Μantaka, Penelope Nikolaou, Michael Oikonomou, George Papatheodoridis, Dimitrios Polymeros, Epameinondas Skouloudis, Konstantinos Soufleris, Evdoxia Stergiou, Aggelos Theodoulou, Angeliki Theodoropoulou, Georgios Theoxaris, Styliani Tsafaraki, Georgia Tsiolakidou, Eftychia Tsironi, Maria Tzouvala, Nikos Viazis, Spyridon Michopoulos, Giorgos Bamias, Evanthia Zampeli
BACKGROUND: Inflammatory bowel disease (IBD) commonly affects patients of reproductive age. The effect of disease activity on the outcome of pregnancy and its impact on neonatal health are areas of intense research. METHODS: Α national retrospective study of pregnancies in women with IBD between 2010 and 2020 was carried out in 22 IBD reference centers in Greece. RESULTS IN TOTAL: 223 pregnancies in 175 IBD patients [122 Crohn's disease (CD)] were included...
September 23, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/39324898/the-primary-cause-of-markedly-elevated-aminotransferases-in-hospitalized-patients-with-cirrhosis-in-ischemic-hepatitis
#6
JOURNAL ARTICLE
Jad Allam, Ahmed Ibrahim, Don C Rockey
BACKGROUND: Marked elevation in aminotransferases (≥1000 IU/l) is typically associated with acute liver injury. Here, we hypothesized that the cause of elevation in aminotransferases ≥1000 in patients with cirrhosis is likely due to a limited number of disorders and may be associated with poor outcomes. AIM: We aimed to investigate the most common etiologies of acute elevations in aminotransferases in patients with cirrhosis, and to examine their associated outcomes...
September 23, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/39324889/adherence-to-patient-blood-management-strategy-in-patients-with-gastrointestinal-bleeding-a-prospective-nationwide-multicenter-study
#7
JOURNAL ARTICLE
Javier Tejedor-Tejada, María Pilar Ballester, Francisco Jose Del Castillo-Corzo, Sandra García-Mateo, María Jose Domper-Arnal, Pablo Parada-Vazquez, Rosa M Saiz-Chumillas, Manuel Alfonso Jiménez-Moreno, Gadea Hontoria-Bautista, Belén Bernad-Cabredo, Concepción Gómez, María Capilla, Margarita Fernández-De La Varga, Lara Ruiz-Belmonte, Berta Lapeña-Muñoz, María Calvo Iñiguez, María Fraile-González, Pablo Flórez-Díez, Víctor Jair Morales-Alvarado, Pedro G Delgado-Guillena, Pablo Cañamares-Orbis, Esteban Saez-González, Natalia García-Morales, Miguel Montoro, Óscar Murcia-Pomares
INTRODUCTION: Patient blood management (PBM) adherence in clinical practice is unclear. This real-world practice study assessed the management of patients with gastrointestinal (GI) bleeding after the implementation of the PBM strategy. METHODS: This was a nationwide multicenter and prospective study involving consecutive adults with GI bleeding between March 2019 and March 2021. Patients were examined according to hemoglobin (Hb) level at admission (<7 g/dl, n = 93; 7-8 g/dl, n = 47; 8-9 g/dl, n = 61; and >9 g/dl, n = 249)...
September 23, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/39324963/long-term-real-world-data-of-ustekinumab-in-ulcerative-colitis-the-stockholm-ustekinumab-study-stocuste
#8
JOURNAL ARTICLE
Haider Sabhan, Francesca Bello, Samer Muhsen, Alexandra Borin, Fredrik Johansson, Charlotte Höög, Ole Forsberg, Christina Wennerström, Mikael Lördal, Sven Almer, Charlotte Söderman
BACKGROUND: Ustekinumab (UST) is an anti-interleukin-12/23 antibody used in the treatment of inflammatory bowel disease. This study includes patients treated at four hospitals in Stockholm to provide long-term real-world data. METHODS: Retrospective study including patients diagnosed with ulcerative colitis and treated with UST between the years 2019 and 2021. Patients were followed until withdrawal of treatment, or until a predefined end of study, 31 July 2021...
September 20, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/39324929/risk-factors-for-unclear-margin-in-cold-snare-polypectomy-for-colorectal-polyp
#9
JOURNAL ARTICLE
Ryosuke Ikeda, Hiroaki Kaneko, Hiroki Sato, Hideyuki Anan, Yuichi Suzuki, Aya Ikeda, Yoshihiro Goda, Soichiro Sue, Kuniyasu Irie, Shin Maeda
OBJECTIVES: Cold snare polypectomy (CSP) is a common, simple, and safe procedure; however, it has a high rate of unclear margins. We analyzed the risk factors for unclear margins of colorectal polyp. METHODS: We retrospectively investigated colorectal polyps treated with CSP between July 2021 and July 2022, excluding those that could not be retrieved or pathologically nonneoplastic and hyperplastic polyps without margin evaluation. The clinicopathological features and risk factors for unclear margins were analyzed...
September 20, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/39292982/investigating-the-prevalence-burden-of-peptic-ulcer-disease-in-older-adults-aged-70-from-1990-to-2019-an-analysis-of-global-disease-burden-studies
#10
JOURNAL ARTICLE
Mingxing Zhuo, Meiling Fang, Ying Yin, Jin Wang, Zhaoxia Wei, Jiaming Lu, Yegui Jia
BACKGROUND: Peptic ulcer disease (PUD) affects individuals aged ≥70 years globally, exerting a significant impact on their health and well-being. Understanding its epidemiological evolution and associated factors is crucial for guiding interventions and improving management. METHODS: This study utilized Global Burden of Disease Study data to examine the prevalence and temporal changes of PUD in individuals aged 70 years and older between 1990 and 2019. The analysis included assessing estimated annual percentage changes (EAPCs) to investigate temporal trends and regional variations...
September 12, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/39292974/the-role-of-new-inflammatory-indices-in-the-prediction-of-endoscopic-and-histological-activity-in-inflammatory-bowel-disease-patients
#11
JOURNAL ARTICLE
Nicola Cesaro, Marco Valvano, Sabrina Monaco, Gianpiero Stefanelli, Stefano Fabiani, Filippo Vernia, Stefano Necozione, Angelo Viscido, Giovanni Latella
BACKGROUND AND AIM: Inflammatory indices are promising indicators that can be used to evaluate inflammation in inflammatory bowel diseases (IBDs). The present study aimed to investigate the test accuracy of several inflammatory indices to identify endoscopic, and histological activity in a cohort of IBD patients. STUDY: All IBD patients who underwent colonoscopy and blood examination (within 4 weeks and without therapeutic change) were included. For these patients, 10 different inflammatory biomarkers were collected...
September 12, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/39292973/systematic-review-with-meta-analysis-of-the-effectiveness-of-subcutaneous-biologics-versus-intravenous-biologics-in-inflammatory-bowel-diseases
#12
JOURNAL ARTICLE
Alexander T Elford, Rishni Heldt, Shahed Kamal, Britt Christensen, Jonathan P Segal
BACKGROUND: Biologic therapies are commonly used for inflammatory bowel disease (IBD) patients. Multiple biologic medicines can now be given both intravenously and subcutaneously. The different administration routes present provide different advantages regarding dose escalation, healthcare resource utilisation, pharmacokinetics, convenience and safety. Comparator effectiveness studies between intravenous and subcutaneous administration are lacking. AIM: Our primary outcome was to compare the effectiveness between intravenous and subcutaneous biologics in rates of clinical remission...
September 12, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/39292971/inflammatory-bowel-disease-and-pulmonary-embolism-a-nationwide-perspective
#13
JOURNAL ARTICLE
Mohammad Aldiabat, Laith Alhuneafat, Omar Al Ta'ani, Saba Altarawneh, Wesam Aleyadeh, Taimur Almuzamil, Ali Butt, Majd Alahmad, Mahmoud Y Madi, Khaled Alsabbagh, Malek Ayoub, Yassine Kilani, Saqr Alsakarneh, Fouad Jaber, Adee Alhamdani
OBJECTIVE: To examine the characteristics and outcomes of patients with inflammatory bowel disease (IBD) hospitalized with pulmonary embolism (PE). METHODS: This cross-sectional observational study analyzed data from the 2016 to 2019 National Inpatient Sample to investigate hospitalizations for PE in the USA, stratified by the presence or absence of IBD. Adult patients were selected using the International Classification of Diseases, Tenth Revision codes for PE, Crohn's disease, and ulcerative colitis...
September 12, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/39292981/diagnostic-model-for-spontaneous-bacterial-peritonitis-in-cirrhotic-patients-with-ascites-a-multicenter-cohort-study
#14
JOURNAL ARTICLE
Xuehong Yin, Enqiang Qin, Rui Song, Xuli Bao, Jinling Dong, Wei Hou, Wei Hua, Bo Tu, Yuening Zhang, Qinghua Meng
INTRODUCTION: Spontaneous bacterial peritonitis (SBP) is a potentially life-threatening complication of cirrhotic ascites. Early diagnosis and treatment of SBP are essential to improve the survival rates and prognosis of patients. We aimed to identify the predictors of SBP to establish a new noninvasive early diagnostic tool. METHODS: We screened 1618 patients who underwent paracentesis due to cirrhotic ascites between January 2017 and December 2018 in three hospitals...
September 11, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/39292969/clinical-and-biochemical-factors-for-bacteria-in-bile-among-patients-with-acute-cholangitis
#15
JOURNAL ARTICLE
Jin Zhao, Bin Wang, Meidan Zhao, Xinling Pan
BACKGROUND: Acute cholangitis is a clinical syndrome caused by a bacterial infection in the biliary system. The bacteria could exist in the bile before bile drainage despite empirical antibiotic treatment. METHODS: Patients with acute cholangitis admitted to a tertiary hospital in Southeastern China from August 2011 to September 2021 were involved when bile cultures were performed. Patient information before bile cultures and during hospitalization was extracted from the clinical record database...
September 11, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/39248087/a-novel-computed-tomography-enterography-radiomics-combining-intestinal-and-creeping-fat-features-could-predict-surgery-risk-in-patients-with-crohn-s-disease
#16
JOURNAL ARTICLE
Jinfang Du, Fangyi Xu, Xia Qiu, Xi Hu, Liping Deng, Hongjie Hu
OBJECTIVE: The objective of this study is to segment creeping fat and intestinal wall on computed tomography enterography (CTE) and develop a radiomic model to predict 1-year surgery risk in patients with Crohn's disease. METHODS: This retrospective study included 135 Crohn's disease patients who underwent CTE between January and December 2021 (training cohort) and 69 patients between January and June 2022 (test cohort). A total of 1874 radiomic features were extracted from the intestinal wall and creeping fat respectively on the venous phase CTE images, and radiomic models were constructed based on the selected features using the Boruta and extreme gradient boosting algorithms...
August 23, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/39166409/subcutaneous-versus-intravenous-infliximab-therapy-a-real-world-study-toward-higher-drug-concentrations
#17
JOURNAL ARTICLE
Ana Isabel Ferreira, Tiago Lima Capela, Cátia Arieira, Sofia Xavier, José Cotter
BACKGROUND: Recently, a formula of subcutaneous infliximab (SC-IFX) has been approved for inflammatory bowel disease (IBD), demonstrating a better pharmacokinetic and immunogenic profiles, compared to intravenous infliximab (IV-IFX), with similar efficacy and safety. AIM: The aim of this study is to evaluate the clinical, biochemical, and pharmacological outcomes of IBD patients in clinical remission, who switched from IV-IFX to SC-IFX, with a follow-up period of 6 months...
August 19, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/39166402/elucidating-the-non-genetic-risk-factors-for-celiac-disease-an-umbrella-review-of-meta-analyses
#18
JOURNAL ARTICLE
Lampriani Tsali, Evangelos Evangelou, Evangelia Ntzani, Konstantinos Katsanos, Georgios Markozannes, Panagiotis Filis, Konstantinos Tsilidis
OBJECTIVE: The breadth and validity of the associations of nongenetic risk factors with celiac disease (CeD) are elusive in the literature. We aimed to evaluate which of these associations have strong epidemiological credibility and assessed presence and extent of potential literature biases. METHODS: We systematically searched PubMed until April 2024 for systematic reviews and meta-analyses of studies examining associations between putative risk factors and CeD...
August 19, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/39166415/reproductive-and-pregnancy-control-in-wilson-disease-patients-in-spain
#19
JOURNAL ARTICLE
Marta Romero-Gutiérrez, Pablo Alonso, Marina Berenguer, Antonio Olveira, María Luisa González-Diéguez, Paula Iruzubieta, Helena Masnou, Manuel Delgado, Manuel Hernández-Guerra, Sara Lorente, María Lázaro, José María Moreno-Planas, Concepción González, Paula Fernández-Álvarez, Francisca Cuenca, Judith Gómez, Luis García-Villareal, Olga Rodríguez, Zoe Mariño
BACKGROUND AND AIM: Recommendations on pregnancy, lactation, and contraception in women with Wilson disease are briefly stated in international guidelines but are not entirely homogeneous. Data regarding the management of these special events among patients with Wilson disease in Spain are lacking. We used the Wilson Registry platform of the Spanish Association for the Study of the Liver to question patients on their reproductive and gestational lives. METHODS: This was a multicentre ambispective study including adult women with Wilson disease in the Spanish Wilson Registry interviewed about their contraception, childbearing, pregnancy, and lactation experiences...
August 14, 2024: European Journal of Gastroenterology & Hepatology
https://read.qxmd.com/read/39083053/patients-with-cardinal-symptoms-of-eosinophilic-esophagitis-prejudice-affects-clinical-practice%C3%A2
#20
JOURNAL ARTICLE
Theodoros Voulgaris, Theodoros Alexopoulos, Jiannis Vlachogiannakos, Dimitrios Kamberoglou, Andreas Koutsoumbas, Kostantinos Papaxoinis, Paraskeyi Fytily, George Papatheodoridis, George P Karamanolis
INTRODUCTION: Dysphagia and bolus impaction are the cardinal manifestations of eosinophilic esophagitis (EoE). Esophageal biopsy sampling is mandatory for EoE diagnosis, data though suggest that clinician do not always obtain biopsies from patients with cardinal EoE symptoms during upper gastrointestinal endoscopy even if no other entity than EoE can explain patients symptoms. We aimed to search for the esophageal biopsy procurement rate as also for factors that drive clinicians to obtain esophageal biopsies among patients with cardinal EoE symptoms...
July 31, 2024: European Journal of Gastroenterology & Hepatology
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