Jacob J Crouse, Shin Ho Park, Daniel F Hermens, Jim Lagopoulos, Minji Park, Mirim Shin, Joanne S Carpenter, Elizabeth M Scott, Ian B Hickie
Protecting brain health is a goal of early intervention. We explored whether sleep quality or chronotype could predict white matter (WM) integrity in emerging mental disorders. Young people (N = 364) accessing early-intervention clinics underwent assessments for chronotype, subjective sleep quality, and diffusion tensor imaging. Using machine learning, we examined whether chronotype or sleep quality (alongside diagnostic and demographic factors) could predict four measures of WM integrity: fractional anisotropy (FA), and radial, axial, and mean diffusivities (RD, AD and MD)...
April 22, 2024: European Journal of Neuroscience