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AIDS Care | Page 2

Jiaying Qiao, Yan Guo, Yajing Zhu, Y Alicia Hong, Zhimeng Xu, Chengbo Zeng, Hanxi Zhang, Weiping Cai, Linghua Li, Cong Liu, Debra K Kellstedt
Few studies have examined the relationship between inconsistent condom use and sexual partnership characteristics among people living with HIV (PLWH). The current study focused on such association and its gender differences. The study was conducted in a large hospital in South China in 2013. A total of 320 dyads (PLWH indexes and their sexual partners) were recruited from an outpatient clinic using convenience sampling. The proportion of inconsistent condom use in the last six months among female indexes was higher than that among male indexes (52...
June 10, 2019: AIDS Care
Joi D Anderson, Xiaoming Li, Shan Qiao, Yuejiao Zhou, Zhiyong Shen
The purpose of this study was to examine the effect of social support as a buffer between traumatic life events and HRQOL. We hypothesized that social support would mediate the effect of traumatic life events on HRQOL. A total of 2987 PLHIV participated in this study. The sample included 1876 (62.8%) males, and 1111 (37.2%) females. Data were collected using survey instruments measuring exposure to traumatic life events, functions of social support and HRQOL. The Structural Equation Model (SEM) produced a chi-square ( χ 2  = 486...
June 7, 2019: AIDS Care
Reuben N Robbins, R Zimmerman, R Korich, J Raymond, C Dolezal, C J Choi, C S Leu, N Nguyen, K Malee, A Wiznia, E J Abrams, C A Mellins
There are an estimated 2.1 million youth less than 15 years of age living with HIV globally (the majority perinatally HIV-infected [PHIV]) and millions more perinatally HIV-exposed uninfected (PHEU) youth who are expected to survive through adolescence and into adulthood. Transitioning from adolescence to young adulthood requires adaptation to more demanding social interactions, academic pressures, and individual responsibilities which place distinct demands on neurocognitive functions. This study examined longitudinal trajectories of neurocognitive test performance in the domains of processing speed (PS), working memory (WM), and executive functioning (EF) among PHIV and demographically similar PHEU from adolescence through young adulthood...
June 7, 2019: AIDS Care
Karen L Cropsey, Madelyne C Bean, Louise Haynes, Matthew J Carpenter, Lauren E Richey
Compared to the general population, persons living with HIV (PLWH) have higher rates of tobacco use and an increased risk of morbidity from tobacco-related diseases. We conducted a single-arm pilot study of the real-world feasibility of integrating a smoking cessation decisional algorithm within routine clinic visits to engage non-treatment-seeking smokers in smoking cessation therapies. Smokers had an initial study visit during routine care followed by phone contacts at one and three months. Participants completed a baseline survey, followed by the algorithm which resulted in a recommendation for a smoking cessation medication, which was prescribed during the visit...
June 7, 2019: AIDS Care
Kevin P Fiori, Hayley M Belli, Molly E Lauria, Lisa R Hirschhorn, Jennifer Schechter, Emily Hansman, Nandita Rajshekhar, Venance Katin, Sesso Gbeleou, Meskerem Grunitsky-Bekele, Vincent Palokinam Pitche
To disseminate lessons learned from the implementation experience of a public-private sector partnership, we describe a comprehensive HIV/AIDS program including 5-year survival outcomes for individuals who initiated antiretroviral therapy (ART) treatment in Togo from 2010 to 2015. A retrospective case study analysis was conducted from a cohort of patients receiving ART at an HIV/AIDS care clinic in Kara Region, Togo. Kaplan-Meier curves with Log rank tests were used to compare estimated survival curves by demographic and clinical characteristics...
June 6, 2019: AIDS Care
Erin M Kahle, Nicholas Suarez, Akshay Sharma, Stephen Sullivan, Rob Stephenson
Gay, bisexual and other men who have sex with men (GBMSM) experience greater health disparities, and concern about other health conditions may decrease engagement in HIV prevention. This study assessed perceived threat and impact of HIV relative to other health concerns among GBMSM. Data were from a national online survey of GBMSM conducted between August and September 2015. Participants ranked concern about contracting HIV and impact of HIV on their health compared with other health conditions. The association of HIV threat and impact with recent condomless anal sex (CAS) and HIV testing were assessed using regression models...
June 5, 2019: AIDS Care
Crystal Chapman Lambert, Andrew Westfall, Riddhi Modi, Rivet K Amico, Carol Golin, Jeanne Keruly, Evelyn Byrd Quinlivan, Heidi M Crane, Anne Zinski, Bulent Turan, Janet M Turan, Michael J Mugavero
Entering HIV care is a vulnerable time for newly diagnosed individuals often exacerbating psychosocial difficulties, which may contribute to poor health-related quality of life (HRQOL) ultimately influencing health behaviors including ART adherence, the driver of viral load suppression. Understanding HRQOL in people newly entering HIV care is critical and has the potential to guide practice and research. This exploratory cross-sectional study examined demographic, clinical, and psychosocial factors associated with limitations in four specific domains of HRQOL among persons initially entering outpatient HIV care at four sites in the United States ( n  = 335)...
June 5, 2019: AIDS Care
M Inghels, S Carillon, A Desgrees du Lou, J Larmarange
The purpose of this paper is to identify which Provider-Initiated HIV Testing and Counseling (PITC) organizational models are the most efficient to maximize testing coverage. We conducted a systematic literature review to identify published articles that evaluated routine PITC programs implemented in adult health facilities in Sub-Saharan Africa. We considered only articles measuring PITC offer, PITC acceptability and PITC coverage. Adjusted meta-regression models were performed to measure the association between PITC offer, acceptability and coverage with PITC organizational model...
June 4, 2019: AIDS Care
Jennifer P Jain, Steffanie A Strathdee, Thomas L Patterson, Shirley J Semple, Alicia Harvey-Vera, Carlos Magis-Rodríguez, Gustavo Martinez, Heather A Pines
Female sex workers (FSWs) experience syndemic factors (e.g., polydrug use, hazardous alcohol consumption, client-perpetrated violence, depression, and sexually transmitted infections) that often heighten vulnerability to HIV and limit healthcare utilization. We hypothesized that syndemic factors will limit FSWs' uptake of pre-exposure prophylaxis (PrEP). From 2016 to 2017, 295 HIV-negative FSWs were enrolled in a behavioral HIV prevention trial in Tijuana and Ciudad Juarez, Mexico, underwent STI testing, and completed surveys on syndemic factors and perceived barriers to PrEP use...
June 4, 2019: AIDS Care
Tareerat Chemnasiri, Anchalee Varangrat, K Rivet Amico, Anupong Chitwarakorn, Bonnie J Dye, Robert M Grant, Timothy H Holtz
The HPTN 067/ADAPT Study evaluated the feasibility, acceptability, patterns of adherence and coverage for three randomly assigned oral FTC/TDF pre-exposure prophylaxis (PrEP) dosing regimens to prevent HIV infection. Using qualitative methods, we explored facilitators and barriers among a subset of men who have sex with men (MSM) participants in Bangkok, Thailand. Between August 2013 and March 2014, 32 HPTN 067/ADAPT participants joined in 6 focus group discussions, and 6 attended key informant interviews. Facilitators of PrEP adherence included use of strategies to have PrEP available when needed, simplicity in regimen requirements with recognition that more complex regimens may take some time to master, ability to plan for sex, receipt of social and technology support, ability to use a PrEP regimen that best matches to one's own patterns of sex, and experiences with PrEP as a part of health and well-being...
June 3, 2019: AIDS Care
Kimiyo Kikuchi, Yusuke Furukawa, Sovannary Tout, Khuondyla Pal, Chantheany Huot, Siyan Yi
This cross-sectional study aimed to identify social, clinical, and behavioral factors associated with the oral health status of children living with HIV in Phnom Penh, focusing particularly on the effect of primary caregiver type. Data were collected through separate interviews with children and caregivers. The decayed, missing, filled permanent teeth (DMFT) index and debris index scores were assessed for each child. Associations between oral health status and caregiver type as well as with other factors were examined using multiple linear regression...
June 3, 2019: AIDS Care
Tarandeep Anand, Chattiya Nitpolprasert, Jureeporn Jantarapakde, Ratchadaporn Meksena, Sangusa Phomthong, Petchfa Phoseeta, Praphan Phanuphak, Nittaya Phanuphak
We conducted a randomized control trial to evaluate the impact of a novel technology-based intervention on HIV risks and condom use behaviors among Thai men who have sex with men (MSM). Between April 2016 and August 2017, participants aged 18 years and above, and having engaged in unprotected sex in past six months were randomly assigned to control and intervention arm, and received HIV testing at baseline, month 6 and 12. Intervention arm participants engaged in 12-monthly HIV/STI prevention educational sessions delivered via Vialogues...
June 2, 2019: AIDS Care
Tyler B Wray, Philip A Chan, Erik M Simpanen
HIV self-test (HST) kits have been available for purchase directly by consumers since 2012. However, public health and prevention programs have been slow to adopt self-testing as a strategy for improving testing rates and regularity, in part due to concerns about its effects on the well-being of users and lack of follow-up. This study explored whether there were differences in several constructs related to well-being, including health-related quality of life, social support, health empowerment, and emotional distress, across those who used HSTs versus tested at a clinic over time...
May 31, 2019: AIDS Care
Cui Yang, Nandita Krishnan, Earl Kelley, Jaidence Dawkins, Omolola Akolo, Rashaunna Redd, Ayodeji Olawale, Commia Max-Browne, Luke Johnsen, Carl Latkin, Kathleen R Page, Melissa Davey-Rothwell
Pre-exposure prophylaxis (PrEP) could have a substantial impact on the HIV epidemic within the US. However, the implementation of PrEP interventions outside of clinical trials has been slow and faces considerable barriers. The aim of the current study was to qualitatively explore PrEP-related patient-reported outcomes (PRO) among MSM patients who enrolled in a PrEP program at two public STD clinics in Baltimore. We conducted in-depth interviews with 18 PrEP patients who self-identified as MSM at two Baltimore City Health Department STD clinics between March and November, 2017...
May 30, 2019: AIDS Care
Uriel R Felsen, Lucia V Torian, Donna C Futterman, Stephen Stafford, Qiang Xia, David Allan, David Esses, Chinazo O Cunningham, Jeffrey M Weiss, Barry S Zingman
Screening for HIV in Emergency Departments (EDs) is recommended to address the problem of undiagnosed HIV. Serosurveys are an important method for estimating the prevalence of undiagnosed HIV and can provide insight into the effectiveness of an HIV screening strategy. We performed a blinded serosurvey in an ED offering non-targeted HIV screening to determine the proportion of patients with undiagnosed HIV who were diagnosed during their visit. The study was conducted in a high-volume, urban ED and included patients who had blood drawn for clinical purposes and had sufficient remnant specimen to undergo deidentified HIV testing...
May 30, 2019: AIDS Care
Pei Qin, Jianmei He, Zixin Wang, Xi Chen, Jinghua Li, Ada Wai Tung Fung, Hui Jiang, Jie Chen, Anna Wong, Joseph Tak Fai Lau
This study was to compare global and domain-specific neurocognitive performance between older people living with HIV (PLWH) taking/not taking efavirenz (EFV) and HIV-negative controls. A cross-sectional study was conducted in Yongzhou city, China. All PLWH older than 50 years listed on the registry of Centres for Disease Control and Prevention were invited to join the study. Frequency matching was used to sample HIV-negative controls according to the distribution of age, sex, and years of formal education of older PLWH...
May 30, 2019: AIDS Care
Babayemi O Olakunde, Daniel A Adeyinka, John O Olawepo, Jennifer R Pharr
HIV testing among men is critical to ending the HIV epidemic in sub-Saharan Africa. Using the Multiple Indicator Cluster Survey, 2016/2017, we examined the uptake and determinants of HIV testing among sexually active men in Nigeria. A total of 1254 young people (15-24 years) and 7866 adults (25-49 years) were included in the analysis. We conducted binary logistic regression analyses to estimate the odds ratio (OR) and adjusted OR for testing for HIV in the last 12 months preceding the survey. Approximately 18...
May 29, 2019: AIDS Care
Sarah MacCarthy, Alexandra Mendoza-Graf, Uzaib Saya, Clare Samba, Josephine Birungi, Stephen Okoboi, Sebastian Linnemayr
ABSTRACT Evidence suggests that simple text messaging interventions may not suffice to improve ART adherence among youth in low-resource settings. To address this shortcoming, we developed an intervention that shared weekly real-time adherence feedback to youth in Uganda using short message services (SMS), based on information tracked by an electronic device (Wisepill). We present results from 7 formative and 6 exit focus groups (FGs) in Mulago and Entebbe, Uganda with youth ages 15-24, providers, and Community Advisory Board members...
May 28, 2019: AIDS Care
Pariya L Fazeli, Steven Paul Woods, C Ann Gakumo, Michael J Mugavero, David E Vance
Engagement in care is a key component of the HIV treatment cascade and is influenced by biopsychosocial factors. Little is known about the association of health literacy with this impactful outcome in people living with HIV (PLWH). Ninety-five PLWH completed a comprehensive battery including health literacy measures covering several domains (i.e., numeracy, reading, self-efficacy, and ability to appraise and access health information). Engagement in care was operationalized as missed clinic visits (i.e., proportion of clinic visits in the prior 24 months where the participant did not attend and did not cancel or reschedule)...
May 28, 2019: AIDS Care
Lalita Wattanachanya, Jureeporn Jantrapakde, Anchalee Avihingsanon, Reshmie Ramautarsing, Stephen Kerr, Deondara Trachunthong, Kanitta Pussadee, Nipat Teeratakulpisarn, Tanate Jadwattanakul, Tawatchai Chaiwatanarat, Patinut Buranasupkajorn, Nittaya Phanuphak, Sarat Sunthornyothin, Praphan Phanuphak
There are limited studies regarding bone health among people living with HIV (PLHIV) in Asia. We compared bone mineral density (BMD), serum 25-hydroxyvitamin D (25(OH)D) status and bone turnover markers (serum procollagen type1 N-terminal propeptide (P1NP), osteocalcin (OC) and C-terminal cross-linking telopeptide of type1 collagen) among 302 antiretroviral therapy (ART) naive PLHIV compared to 269 HIV-uninfected controls from Thailand. People aged ≥30 years, with and without HIV infection (free of diabetes, hypertension, and active opportunistic infection) were enrolled...
May 28, 2019: AIDS Care
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