Kai Xia, Renyuan Gao, Lin Li, Xiaocai Wu, Tianqi Wu, Yu Ruan, Lu Yin, Chunqiu Chen
Intestinal inflammation modifies host physiology to promote the occurrence of colorectal cancer (CRC), as seen in colitis-associated CRC. Gut microbiota is crucial in cancer progression, primarily by inducing intestinal chronic inflammatory microenvironment, leading to DNA damage, chromosomal mutation, and alterations in specific metabolite production. Therefore, there is an increasing interest in microbiota-based prevention and treatment strategies, such as probiotics, prebiotics, microbiota-derived metabolites, and fecal microbiota transplantation...
September 6, 2023: Critical Reviews in Microbiology