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Clinical Imaging

Füsun Taşkın, Yasemin Polat, İbrahim H Erdoğdu, Aykut Soyder
PURPOSE: Pregnancy-associated breast cancer (PABC) is a rare disease. However, its expected incidence tends to be increased because of delayed maternal age. The purpose of this study was to describe the clinical, radiological, and histopathological characteristics of PABC cases diagnosed in our center. METHODS: The clinical-radiological findings and histopathological characteristics of patients diagnosed and treated with PABC at our institution between January 2011 and January 2017 were retrospectively evaluated...
August 5, 2019: Clinical Imaging
Nanki Hura, Amrita-Amanda D Vuppala, Sadaf Sahraian, Elham Beheshtian, Neil R Miller, David M Yousem
PURPOSE: In a recent study, it was found that, although intrinsic midbrain signal abnormality (IMSA) on MRI is associated with Parinaud's syndrome (PS) in patients with pineal gland masses (PM), it had no predictive value with respect to resolution of PS. We sought to compare the PM and non-pineal etiologies (NPE) of PS by reviewing imaging features of PS and whether or not they are predictive of resolution of symptoms. METHODS: We reviewed electronic medical records from 1980 to 2017 and identified 71 patients with PS from any etiology who had MR imaging: 26 with PM and 45 with NPE...
July 24, 2019: Clinical Imaging
Heather Kimball, David Kimball, Alan Siroy, Ibrahim Sacit Tuna, Brian J Boyce, Mehmet Sait Albayram
Lupus panniculitis (LP), also referred to as lupus erythematosus profundus (LEP), is a chronic recurrent inflammation condition of the subcutaneous fat. It occurs in 1 to 3% of patients with systemic lupus erythematosus (SLE) and in 10% of patients with discoid lupus erythematosus (DLE), but can also occur as an entity of its own. Patients with lupus panniculitis usually present with persistent, often tender and painful skin lesions, or subcutaneous nodules, that range from 1 to 5 cm in diameter. The overlying skin may appear erythematous; lesions may become ulcerated, and heal with atrophy, skin depression, dimpling and scaring...
July 23, 2019: Clinical Imaging
Elizabeth Lee, Joel Platt, Prachi P Agarwal
We report the case of a 36 year old male who demonstrated extensive high attenuation in the muscles of the chest wall and neck on a noncontrast chest CT. The high attenuation in the musculature was due to calcium, sequela from a recent episode of rhabdomyolysis. Although the diagnosis of rhabdomyolysis is made on clinical grounds, the imaging appearance can be confusing given the variability in appearance of rhabdomyolysis depending on the severity and the timeline of disease.
July 23, 2019: Clinical Imaging
Jordan B Rapp, Sean Ciullo, Mary G Mallon
A 15 year old female with a history only significant for long standing dysphagia and intermittent chest pain underwent a screening chest radiograph. Findings of a large mass prompted cross sectional imaging where extensive and marked diffuse esophageal thickening was demonstrated. The patient ultimately underwent biopsy and surgical resection for diffuse esophageal leiomyomatosis. Diffuse leiomyomatosis of the esophagus has been described in the literature for about 100 years with increasing recognition in more recent times...
July 23, 2019: Clinical Imaging
Lauren Q Chang Sen, Monica L Huang, Jessica W T Leung, Wei Wei, Beatriz E Adrada
OBJECTIVE: To determine the malignancy rate in women without a concurrent breast cancer diagnosis at presentation who underwent stereotactic biopsies of distinct sites of suspicious calcifications. METHODS: This retrospective study included 280 women without a concurrent breast cancer diagnosis who underwent 587 stereotactic biopsies of two or more distinct sites of suspicious calcifications in one or both breasts at our institution from 2010 to 2015. RESULTS: The overall malignancy rate was 27...
July 23, 2019: Clinical Imaging
Aparna Singhal, Paul R Gohlke, Philip R Chapman
Cases of spontaneous CSF leak associated with pituitary tumor apoplexy are uncommon in the literature with pneumocephalus or pneumosella being rare, especially spontaneous occurrence of pneumocephalus being extremely rare. We present a case of pituitary macroadenoma apoplexy resulting in spontaneous CSF leak and a large volume of intra-tumoral gas. A 65-year-old female presented with severe headache, profuse rhinorrhea and acute vision loss and was found to have a large sellar and suprasellar lesion with air and hemorrhage with mild peripheral enhancement...
July 23, 2019: Clinical Imaging
William M Sherk, Minhaj S Khaja, Eric D Good, Ryan T Cunnane, Narasimham L Dasika, David M Williams
PURPOSE: The purpose of this study was to describe the safety and efficacy of hybrid recanalization procedures in a series of patients with obstructed central veins requiring cardiac implantable electronic device (CIED) revision. METHODS: Between 2008 and 2016, 38 consecutive patients (24 M; age 60.5 ± 16.2 years; range 25-87 years) with central venous obstruction underwent 42 recanalization interventions performed in conjunction with CIED revision or extraction...
July 14, 2019: Clinical Imaging
Mary Salvatore, Ayushi Singh, Rowena Yip, Esther Fevrier, Claudia I Henschke, David Yankelevitz, Maria Padilla
PURPOSE: To determine patterns of progression of probable Usual Interstitial Pneumonitis (UIP). METHODS: This HIPPA compliant, IRB-approved study draws patients from our Fibrosis Registry. All patients with a consensus diagnosis of Idiopathic Pulmonary Fibrosis (IPF) were included. Most recent CT scans and all earlier CT scans were reviewed to determine the fibrosis grade in each lobe based on probable UIP (pUIP) findings of ground glass opacities, traction bronchiolectasis and reticulations or UIP findings of subpleural basilar predominant fibrosis with honeycombing (HC) and absence of features that would suggest an alternative diagnosis...
July 12, 2019: Clinical Imaging
Yong Wei Liu, Mark D Tran, Matthew R Skalski, Dakshesh B Patel, Eric A White, Anderanik Tomasian, Jordan S Gross, C Thomas Vangsness, George R Matcuk
Articular cartilage is a complex tissue with unique properties that are essential for normal joint function. Many processes can result in cartilage injury, ranging from acute trauma to degenerative processes. Articular cartilage lacks vascularity, and therefore most chondral defects do not heal spontaneously and may require surgical repair. A variety of cartilage repair techniques have been developed and include bone marrow stimulation (microfracture), osteochondral autograft transfer system (OATS) or osteochondral allograft transplantation, autologous chondrocyte implantation (ACI), matrix-assisted chondrocyte implantation (MACI), and other newer processed allograft cartilage techniques...
July 11, 2019: Clinical Imaging
Ana Germano, Willian Schmitt, Manuel Rio Carvalho, Rui M Marques
High-resolution ultrasound is considered the best imaging technique for evaluating the thyroid gland, as it is accessible, non-invasive, and highly sensitive concerning the detection and characterization of thyroid nodules. However, a background knowledge of the normal ultrasound anatomy of the thyroid gland, adjacent structures, and its anatomical variants is crucial to avoid misdiagnosis in daily practice. Through this pictorial review, we intend to.
July 10, 2019: Clinical Imaging
Yildizhan Sengul, Hafize Otcu, Ismet Ustun, Hakan S Sengul, Tess Cersonsky, Alpay Alkan, Elan D Louis
OBJECTIVE: Patients with essential tremor (ET) may exhibit non-motor features, including those that are neuropsychiatric. Depression and anxiety are the most common among these. This study aims to investigate the possible relationship between microstructural brain changes and symptoms of depression and anxiety in ET. METHODS: We assessed 62 ET patients (40 women and 22 men, mean age 46.0 ± 20.4) for symptoms of depression and anxiety using the Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI)...
June 27, 2019: Clinical Imaging
Amy N Melsaether, Eric Kim, Eralda Mema, James Babb, Sungheon Gene Kim
BACKGROUND: Dynamic contrast enhanced (DCE) breast MRI is highly sensitive for breast cancer and requires gadolinium-based contrast agents (GBCA)s, which have potential safety concerns. PURPOSE: Test whether breast cancers imaged by 3T DCE breast MRI with 0.05 mmol/kg of gadobutrol are detectable. METHODS: Analysis of 3T DCE breast MRIs with half dose of gadobutrol from patients included in an IRB-approved and HIPPA-compliant prospective study of breast PET/MRI...
June 27, 2019: Clinical Imaging
Kai-Hsiung Ko, Tsai-Wang Huang, Shih-Chun Lee, Wei-Chou Chang, Hong-Wei Gao, Hsian-He Hsu
OBJECTIVE: To assess the efficacy of computed tomography (CT)-guided localization with the injection of a low dose of patent blue dye (PBD) for the thoracoscopic resection of pulmonary nodules. MATERIALS AND METHODS: Overall, 125 consecutive patients underwent CT-guided localization with injection of a lower dose of PBD between June 2015 and June 2016. The total injection dose relative to the distance between nodules and the visceral pleura was recorded. The clinical and radiological characteristics, technical details, pathological results and procedure-related complications were reviewed...
June 27, 2019: Clinical Imaging
Jing Gao, Andy Thai, Todd Erpelding
PURPOSE: The aim of the study was to compare Superb Microvascular Imaging (SMI) to conventional color Doppler ultrasonography (CDUS) and power Doppler ultrasonography (PDUS) in depicting kidney cortical microvasculature. METHODS: Using 3.5 MHz curve-linear array ultrasound transducer and manufacturer recommended color Doppler settings (Canon Medical Systems) for KIDNEY sonography, we performed kidney CDUS, PDUS, and SMI in 20 healthy adults (10 man and 10 women, mean age 27 years)...
June 22, 2019: Clinical Imaging
Joshua Cornman-Homonoff, Tamatha B Fenster, Marc H Schiffman
Endometrioma superinfection is uncommon and poorly described in the literature. This rarity has precluded agreement on optimal management, with most authors treating these lesions as endometriomas rather than abscesses and thus recommending laparoscopic or open cystectomy or oophorectomy. We present a minimally-invasive alternative, illustrated in the case of an infected endometrioma which was successfully managed via image-guided percutaneous drainage.
June 22, 2019: Clinical Imaging
Sana Salehi, Aidin Abedi, Jordan S Gross, Ali Gholamrezanezhad
Insufficiency fractures are a relatively common sub-type of stress fractures and occur as a result of decreased bone resistance due to underlying conditions such as osteoporosis. Insufficiency fractures of the knee most commonly occur at the central weight-bearing zone of the medial femoral condyle. We present five unusual cases of insufficiency fractures occurring at the posterior non-weight-bearing zone of condyles. After investigating commonalities between these patients, we discovered that all of these patients performed the daily practice of prayer rituals that include high knee flexion...
June 22, 2019: Clinical Imaging
Aashim Bhatia, Bret C Mobley, Joy Cogan, Mary E Koziura, Elly Brokamp, John Phillips, John Newman, Steven A Moore, Rizwan Hamid
Mutations in the torsinA-interacting protein 1 (TOR1AIP1) gene result in a severe muscular dystrophy with minimal literature in the pediatric population. We review a case of TOR1AIP1 gene mutation in a 16-year-old Caucasian female with a long history of muscle weakness. Extensive clinical workup was performed and MRI at time of initial presentation demonstrated no significant muscular atrophy with heterogenous STIR hyperintensity of the lower extremity muscles. MRI findings seven years later included extensive atrophy of the lower extremities, with severe progression, including the gluteal muscles, iliopsoas, rectus femoris, and obturator internus...
June 21, 2019: Clinical Imaging
Alexandra Christou, Vassilis Koutoulidis, Dimitra Koulocheri, Evangelia Panourgias, Aphrodite Nonni, Constantinos G Zografos, George C Zografos
OBJECTIVES: To retrospectively assess the stereotactic one-pass BLES performance in excision of small groups of calcifications seen on mammogram that proved to be papillomas. METHODS: Between January 2014 and January 2016, 37/400 cases (9.2%) of stereotactic BLES biopsies performed in our department due to suspicious calcifications proved to be papillomas. Lesions with atypia underwent surgical removal and lesions with no atypia were followed up for 2 years. BLES and surgical histology results, radiological removal and 2-years stability were statistically analysed to assess BLES performance in biopsy and excision of papillomas...
June 18, 2019: Clinical Imaging
James E Siegler, Glenn Konsky, Christopher Renner, Andres Moreno-De-Luca, David Gutman, Brett Cucchiara, Steven R Messé
INTRODUCTION: Cervical internal carotid artery (ICA) atherosclerotic plaque and stenosis is often asymmetric. We hypothesized that hyoid bone proximity to the ICA also may be asymmetric and may increase the risk of traumatic endothelial injury and accelerate atherosclerotic stenosis. METHODS: A retrospective cross-sectional and longitudinal cohort design evaluated consecutive adult patients at 3 hospitals who underwent repeat computed tomography angiography (CTA) of the neck 2 calendar years apart (01/2000-07/2017)...
June 14, 2019: Clinical Imaging
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