Nan Li, Yue Huang, Yang Yi, Jin Qian, Qi Li, Shuang-Qin Xu, Hang-Fei Wang, Xin-Xin Wu, Ji-Chao Peng, Li-Hua Li, Jin-Jian Yao, Xiao-Ran Liu
Background : Paraquat (PQ) plays an important role in agricultural production due to its highly effective herbicidal effect. However, it has led to multiple organ failure in those who have been poisoned, with damage most notable in the lungs and ultimately leading to death. Because of little research has been performed at the genetic level, and therefore, the specific genetic changes caused by PQ exposure are unclear. Methods : Paraquat poisoning model was constructed in Sprague Dawley (SD) rats, and SD rats were randomly divided into Control group, paraquat (PQ) poisoning group and Anthrahydroquinone-2,6-disulfonate (AH2 QDS) treatment group...
January 4, 2024: Inhalation Toxicology