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Biomedical and Environmental Sciences: BES

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https://read.qxmd.com/read/30987699/emergency-response-for-a-laboratory-biosafety-incident
#1
En Min Zhang, Jia Qi Wang, Li Dong Gao, Zhi Fei Zhan, Heng Zhang, Yan Hong Hu, Jian Chun Wei, Xu Dong Liang, Kang Lin Wan, Qiang Wei
On December 14, 2017, a faculty member of a university in Hunan Province reported that an anthrax vaccine strain might have recovered virulence during an undergraduate experiment and potential exposure could not be ruled out for the students involved. Upon receiving the case report, the CDC, health bureaus, and local governments at the county, prefectural, and provincial levels promptly organized experts in different fields (including epidemiologists, biosafety experts, and laboratory testing experts) for case investigation, evaluation, and response...
March 2019: Biomedical and Environmental Sciences: BES
https://read.qxmd.com/read/30987698/the-effect-of-beta-2-adrenergic-receptor-genetic-variants-on-vasopressor-requirements-in-surgery-patients-a-meta-analysis
#2
Qi Zheng Pan, Jia Hong Shi, Yun Li, Ming Gao, Shu Ping Ren, Guo Qing Zhao
No abstract text is available yet for this article.
March 2019: Biomedical and Environmental Sciences: BES
https://read.qxmd.com/read/30987697/htr-and-grin2b-variant-associated-with-cognition-dysfunction-in-electric-workers
#3
Li Feng Wang, Hai Juan Li, Cai Xia Ren, Yong Zou, Si Mo Qiao, Wei Jia Zhi, Chang Zhen Wang, Li Zhao, Ji Dong, Xin Ping Xu, Shao Hua Hu, Rui Yun Peng, Xiang Jun Hu
No abstract text is available yet for this article.
March 2019: Biomedical and Environmental Sciences: BES
https://read.qxmd.com/read/30987696/comparison-of-xpert-mtb-rif-realamp-and-cpa-tests-in-detecting-mycobacterium-tuberculosis
#4
Xi Chao Ou, Hui Li, Dong Xin Liu, Hui Xia, Xiao Guang Ma, Shao Hua Wang, Sheng Fen Wang, Yan Kun Zhu, Bing Zhao, Yan Lin Zhao
No abstract text is available yet for this article.
March 2019: Biomedical and Environmental Sciences: BES
https://read.qxmd.com/read/30987695/prevalence-and-genotypes-of-rotavirus-a-and-human-adenovirus-among-hospitalized-children-with-acute-gastroenteritis-in-fujian-china-2009-2017
#5
Bing Shan Wu, Zhi Miao Huang, Yu Wei Weng, Feng Qin Chen, Yun Lin Zhang, Wei Dong Lin, Ting Ting Yu
No abstract text is available yet for this article.
March 2019: Biomedical and Environmental Sciences: BES
https://read.qxmd.com/read/30987694/cis-2-dodecenoic-acid-mediates-its-synergistic-effect-with-triazoles-by-interfering-with-efflux-pumps-in-fluconazole-resistant-candida-albicans
#6
Dong Liang Yang, Yan Ling Hu, Zi Xin Yin, Gui Sheng Zeng, Dan Li, Yu Qian Zhang, Zhen Hua Xu, Xiao Ming Guan, Li Xing Weng, Lian Hui Wang
OBJECTIVE: To evaluate the synergy of the Burkholderia signaling molecule cis-2-dodecenoic acid (BDSF) and fluconazole (FLU) or itraconazole (ITRA) against two azole-resistant C. albicans clinical isolates in vitro and in vivo. METHODS: Minimum inhibitory concentrations (MICs) of antibiotics against two azole-resistant C. albicans were measured by the checkerboard technique, E-test, and time-kill assay. In vivo antifungal synergy testing was performed on mice. Analysis of the relative gene expression levels of the strains was conducted by quantitative reverse-transcription polymerase chain reaction (qRT-PCR)...
March 2019: Biomedical and Environmental Sciences: BES
https://read.qxmd.com/read/30987693/behavioral-abnormality-along-with-nmdar-related-creb-suppression-in-rat-hippocampus-after-shortwave-exposure
#7
Chao Yu, Yan Xin Bai, Xin Ping Xu, Ya Bing Gao, Yan Hui Hao, Hui Wang, Sheng Zhi Tan, Wen Chao Li, Jing Zhang, Bin Wei Yao, Ji Dong, Li Zhao, Rui Yun Peng
OBJECTIVE: To estimate the detrimental effects of shortwave exposure on rat hippocampal structure and function and explore the underlying mechanisms. METHODS: One hundred Wistar rats were randomly divided into four groups (25 rats per group) and exposed to 27 MHz continuous shortwave at a power density of 5, 10, or 30 mW/cm2 for 6 min once only or underwent sham exposure for the control. The spatial learning and memory, electroencephalogram (EEG), hippocampal structure and Nissl bodies were analysed...
March 2019: Biomedical and Environmental Sciences: BES
https://read.qxmd.com/read/30987692/connexin43-modulates-x-ray-induced-pyroptosis-in-human-umbilical-vein-endothelial-cells
#8
Chen Li, Mei Tian, Qiao Gou, Yong Rui Jia, Xu Su
OBJECTIVE: Pyroptosis is an inflammatory form of programmed cell death. This phenomenon has been recently reported to play an important role in radiation-induced normal tissue injury. Connexin43 (Cx43) is a gap junction protein that regulates cell growth and apoptosis. In this study, we investigated the effect of Cx43 on X-ray-induced pyroptosis in the human umbilical vein endothelial cells (HUVECs). METHODS: HUVECs, Cx43 overexpression, and Cx43 knockdown strains were irradiated with 10 Gy...
March 2019: Biomedical and Environmental Sciences: BES
https://read.qxmd.com/read/30987691/combined-effects-of-a-body-shape-index-and-serum-c-reactive-protein-on-ischemic-stroke-incidence-among-mongolians-in-china
#9
Guang Li Wang, Rui Zhang, Yi Ting Zhou, Ai Li Wang, Tian Xu, Ming Zhi Zhang, Hong Mei Li, Yong Hong Zhang
OBJECTIVE: We aimed to evaluate the combined effects of a high body shape index (ABSI) and a high serum C-reactive protein (CRP) level on the incidence of ischemic stroke in a Mongolian population in China. METHODS: A prospective cohort study was conducted among 2,589 participants from June 2002 to July 2012 in Inner Mongolia, China. The participants were categorized into 4 groups according to their level of ABSI and CRP. Cox proportional hazards models were used to assess the hazard ratios (HRs) and 95% confidence intervals (CIs) for ischemic stroke among all groups...
March 2019: Biomedical and Environmental Sciences: BES
https://read.qxmd.com/read/30987690/childhood-bmi-and-adult-obesity-in-a-chinese-sample-a-13-year-follow-up-study
#10
Dan Liu, Yun Xia Hao, Ting Zhi Zhao, Peng Kun Song, Yi Zhai, Shao Jie Pang, Yan Fang Zhao, Mei Zhang, Zhuo Qun Wang, Sheng Quan Mi, Yu Ying Wang, Jian Zhang, Wen Hua Zhao
OBJECTIVE: Obesity is recognized as a significant risk factor for diabetes and hypertension. The present study aimed to examine the associations between adults'obesity risk and childhood and parental obesity. METHODS: A total of 204 children aged 6-17 years were recruited in 2002 with an average follow-up period of 13.2 years. Height and body weight were measured by trained staffs. Overweight and obesity were defined based on the Chinese standard for children and adults...
March 2019: Biomedical and Environmental Sciences: BES
https://read.qxmd.com/read/30987689/hepcidin-orchestrated-hemogram-and-iron-homeostatic-patterns-in-two-models-of-subchronic-hepatic-injury
#11
Ibtsam Gheith, Abubakr El-Mahmoudy
OBJECTIVE: This study was designed to evaluate hematological disorders and the orchestrating roles of hepcidin and IL-6 in rat models of thioacetamide (TAA) and carbon tetrachloride (CCl4) hepatotoxicity. METHODS: Rats were intraperitoneally injected with TAA (10 mg/100 g rat weight dissolved in isosaline) or CCl4 (100 μL/100 g rat weight diluted as 1:4 in corn oil) twice weekly for eight consecutive weeks to induce subchronic liver fibrosis. Blood and tissue samples were collected and analyzed...
March 2019: Biomedical and Environmental Sciences: BES
https://read.qxmd.com/read/30862348/protocol-of-jidong-women-health-cohort-study-rationale-design-and-baseline-characteristics
#12
Meng Si Qiu, Xian Wei Wang, Yan Yao, Si Qi Ge, Hua Min Liu, Ying Chun Dai, Yong Zhou
OBJECTIVE: The Jidong Women Health Cohort Study is a prospective cohort study on female-specific characteristics and risks of chronic diseases in Chinese women and focuses on the potential association between menopause and risks of cardiovascular disease (CVD). METHODS: The study includes 4,179 female participants with an age of older than 18 years from Caofeidian district, Tangshan city, northern China. Baseline information on female-specific characteristics and potential cardiovascular risk factors was collected and all the participants underwent a physical examination with blood samples collected in 2013...
February 2019: Biomedical and Environmental Sciences: BES
https://read.qxmd.com/read/30862347/salidroside-reduces-pde2a-expression-by-down-regulating-p53-in-human-embryonic-lung-fibroblasts
#13
Wen Min Xing, Sha Sha Chen, San Ying Wang, Wen Yan Gao, Xiao Qing Wan, Hui Li Su, Yi Yang, Jing Zhang, Jing Yan, Gen Xiang Mao
No abstract text is available yet for this article.
February 2019: Biomedical and Environmental Sciences: BES
https://read.qxmd.com/read/30862346/projections-of-temperature-related-non-accidental-mortality-in-nanjing-china
#14
Qing Hua Sun, Radley M Horton, Daniel A Bader, Bryan Jones, Lian Zhou, Tian Tian Li
The health effects of climatic changes constitute an important research area, yet few researchers have reported city- or region-specific projections of temperature-related deaths based on assumptions about mitigation and adaptation. Herein, we provide quantitative projections for the number of additional deaths expected in the future, owing to the cold and heat in the city of Nanjing, China, based on 31 global circulation models (GCMs), two representative concentration pathways (RCPs) (RCP4.5 and RCP8.5), and three population scenarios [a constant scenario and two shared socioeconomic pathways (SSPs) (SSP2 and SSP5)], for the periods of 2010-2039, 2040-2069, and 2070-2099...
February 2019: Biomedical and Environmental Sciences: BES
https://read.qxmd.com/read/30862345/risk-assessment-of-moah-and-mosh-in-infants-and-young-children
#15
Lei Zhu, Hong Zhang, Yan Fen Chen, Jing Jing Pan, Ai Dong Liu, Feng Pan, Jian Bo Zhang, Huai Ning Zhong
No abstract text is available yet for this article.
February 2019: Biomedical and Environmental Sciences: BES
https://read.qxmd.com/read/30862344/theoretical-risk-assessment-of-dietary-exposure-to-brilliant-blue-fcf-in-chinese-population
#16
Hua Li Wang, Hao Ding, Pei Cao, Jian Bo Zhang, Di Wu, Jing Tian
No abstract text is available yet for this article.
February 2019: Biomedical and Environmental Sciences: BES
https://read.qxmd.com/read/30862343/serum-alanine-aminotransferase-is-associated-with-metabolic-syndrome-and-10-year-risk-of-cardiovascular-disease
#17
Li Na Ma, Rui DU, Di Cheng, Lin Lin, Xue Yan Wu, Chun Yan Hu, Meng Dai, Yu Xu, Min Xu, Lei Jiang, Mian Li, Jie Li Lu, Yu Fang Bi, Wei Qing Wang, Guang Ning
No abstract text is available yet for this article.
February 2019: Biomedical and Environmental Sciences: BES
https://read.qxmd.com/read/30862342/effect-of-hspb9-on-apoptosis-of-df-1-cells
#18
Yong Jie Xu, Mei Ling Hu, Liang Hui Zhou, Qi Wang, Xi Quan Zhang, Qing Bin Luo
OBJECTIVE: Our aim was to explore whether heat stress protein (HSP) 9 preferentially expresses under heat stress and affects the expression of other heat stress proteins as well as to explore the effect of HSPB9 overexpression and knockdown on apoptosis in DF-1. METHODS: We used gene cloning to construct an overexpression vector of the target gene, and synthesized the target gene interference fragment to transfect the chicken fibroblast cell line. Gene and protein expression, as well as apoptosis, were detected by RT-qPCR, Western blot, and flow cytometry...
February 2019: Biomedical and Environmental Sciences: BES
https://read.qxmd.com/read/30862341/metabolomic-analysis-of-serum-glycerophospholipid-levels-in-eosinophilic-and-neutrophilic-asthma
#19
Xiao Yan Gai, Li Jiao Zhang, Chun Chang, Cheng Lin Guo, Mairipaiti Abulikemu, Wen Xiong Li, Juan Wang, Wan Zhen Yao, Xu Zhang
OBJECTIVE: To compare the serum glycerophospholipid levels in the inflammatory subtypes of asthma by using targeted metabolomic analysis. METHODS: Demographic and clinical data were collected from 51 patients with asthma between January 2015 and December 2015. Routine blood and sputum induction tests were performed. Eosinophilic asthma was defined as induced sputum containing ⪖ 3% eosinophils, and neutrophilic asthma, as induced sputum containing ⪖ 71% neutrophils...
February 2019: Biomedical and Environmental Sciences: BES
https://read.qxmd.com/read/30862340/applying-the-china-par-risk-algorithm-to-assess-10-year-atherosclerotic-cardiovascular-disease-risk-in-populations-receiving-routine-physical-examinations-in-eastern-china
#20
Hui Hua Li, Shan Huang, Xing Zhen Liu, Da Jin Zou
OBJECTIVE: To assess the 10-year Atherosclerotic Cardiovascular Disease (ASCVD) risk score among adults in eastern China using the China-PAR equation which formulated primarily for the Chinese population. METHODS: Data from 72,129 individuals from 35-74 years old who received routine physical examinations in eastern China were analyzed in this study. The 10-year risk scores were calculated using the China-PAR equation. The chi-square test and logistic regression were then performed to evaluate the association between the selected risk factors and overall CVD risk...
February 2019: Biomedical and Environmental Sciences: BES
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