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Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists

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https://read.qxmd.com/read/30955990/dominant-intraprostatic-lesion-boosting-in-sexual-sparing-radiotherapy-of-prostate-cancer-a-planning-feasibility-study
#1
Selena Ciabatti, Maria Ntreta, Milly Buwenge, Caterina Gaudiano, Elisa Sessagesimi, Fabrizio Romani, Anna L Angelini, Silvia Cammelli, Gabriella Macchia, Francesco Deodato, Alice Zamagni, Rita Golfieri, Alessio G Morganti, Savino Cilla
AIM: Radical radiotherapy of prostate cancer requires a relatively high dose to achieve an optimal tumor control probability and a reduced dose to the critical structures related to the sexual function (S_OARs) in order to avoid erectile dysfunction. The aim of this study was to perform a planning feasibility analysis of a 3-level dose prescription with Simultaneous Integrated Boost (SIB) on the dominant intraprostatic lesion (DIL) and with S_OARs sparing. MATERIAL AND METHODS: Twelve patients with clinically localized intermediate risk prostate cancer were included...
April 4, 2019: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://read.qxmd.com/read/30952385/dosimetric-characterization-of-a-rigid-surface-contour-specific-thermoplastic-bolus-material
#2
Jessica M Fagerstrom
A dosimetric analysis of a commercially available thermoplastic sheet bolus, Klarity EZ BolusTM , was completed. Attenuation characteristics were evaluated using different configurations of a rectilinear water-mimicking plastic phantom irradiated by a high-energy linear accelerator using three photon energies, five electron energies. These results were compared with data obtained during the linear accelerator commissioning process to determine depths of water that attenuated beams similarly. CT scans of the flat, unmolded sheet bolus, as well as of the bolus molded to a cylindrical phantom, were analyzed...
April 2, 2019: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://read.qxmd.com/read/30952384/automatizing-a-nonscripting-tps-for-optimizing-clinical-workflow-and-reoptimizing-imrt-vmat-plans
#3
Rafael Ayala, Gema Ruiz, Teresa Valdivielso
The purpose of this study was to design a toolkit that interacts with the Monaco (Elekta AB, Stockholm, Sweden) treatment planning system (TPS) for optimization of intensity-modulated radiation therapy and volumetric-modulated arc therapy without the need for a dedicated application programming interface. Successful inverse planning of radiotherapeutic treatment depends on the tweaking of many parameters; a tool was thus needed to explore these parameters more exhaustively without significantly increasing planning time...
April 2, 2019: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://read.qxmd.com/read/30948342/in-reply-to-letter-to-the-editor-titled-use-of-electronic-portal-images-to-evaluate-setup-error-and-intrafraction-motion-during-free-breathing-breast-intensity-modulated-radiotherapy-imrt-treatment-common-mistake-in-reliability-analysis
#4
LETTER
Jing-Min Hwang, Chiou-Shiung Chang
No abstract text is available yet for this article.
April 1, 2019: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://read.qxmd.com/read/30948341/dosimetric-study-on-learning-based-cone-beam-ct-correction-in-adaptive-radiation-therapy
#5
Tonghe Wang, Yang Lei, Nivedh Manohar, Sibo Tian, Ashesh B Jani, Hui-Kuo Shu, Kristin Higgins, Anees Dhabaan, Pretesh Patel, Xiangyang Tang, Tian Liu, Walter J Curran, Xiaofeng Yang
INTRODUCTION: Cone-beam CT (CBCT) image quality is important for its quantitative analysis in adaptive radiation therapy. However, due to severe artifacts, the CBCTs are primarily used for verifying patient setup only so far. We have developed a learning-based image quality improvement method which could provide CBCTs with image quality comparable to planning CTs (pCTs). The accuracy of dose calculations based on these CBCTs is unknown. In this study, we aim to investigate the dosimetric accuracy of our corrected CBCT (CCBCT) in brain stereotactic radiosurgery (SRS) and pelvic radiotherapy...
April 1, 2019: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://read.qxmd.com/read/30929978/feasibility-of-spine-stereotactic-body-radiotherapy-for-patients-with-large-tumors-in-multiple-vertebrae-undergoing-re-irradiation-dosimetric-challenge-using-3-different-beam-delivery-techniques
#6
Tomohisa Furuya, Jun H Phua, Kei Ito, Katsuyuki Karasawa
The objective of the present study was to report whether the adequate spine stereotactic body radiotherapy (SBRT) plans were generated with feasible treatment duration for patients with large vertebral metastases undergoing re-irradiation. For 5 cases, the re-irradiation plans using static-field intensity-modulated radiation therapy (SIMRT), volumetric-modulated arc therapy (VMAT), and CyberKnife with a total prescribed dose (PD) of 24 Gy applied in 2 fractions were generated. A minimum dose to 95% of the evaluated planning target volume (PTVevl ) that was >70% of PD (D95 > 70% PD) was defined as minimum criterion...
March 28, 2019: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://read.qxmd.com/read/30928177/dosimetric-comparison-of-intensity-modulated-radiation-therapy-for-early-stage-glottic-cancers-with-and-without-the-air-cavity-in-the-planning-target-volume
#7
David Asher, William Amestoy, Matthew T Studenski, Stuart E Samuels, Matthew C Abramowitz, Laura M Freedman, Nagy Elsayyad, Michael A Samuels
For early-stage glottic cancers, intensity-modulated radiation therapy (IMRT) has been shown to have comparable local control to 3D-conformal radiotherapy with the advantage of decreased dose to the carotid arteries. The planning target volume (PTV) for early glottic cancers typically includes the entire larynx, plus a 3 to 5 mm uniform margin. The air cavity within the larynx creates a challenge for the inverse optimization process as the software attempts to "build up" dose within the air. This unnecessary attempt at dose build-up in air can lead to hot spots within the rest of the PTV and surrounding soft tissue...
March 27, 2019: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://read.qxmd.com/read/30871864/evaluation-of-the-effectiveness-of-novel-single-intervention-adaptive-radiotherapy-strategies-based-on-daily-dose-accumulation
#8
Alberto Ciarmatori, Nicola Maffei, Grazia Maria Mistretta, Paola Ceroni, Annalisa Bernabei, Bruno Meduri, Elisa D'Angelo, Alessio Bruni, Patrizia Giacobazzi, Frank Lohr, Gabriele Guidi
Parotid gland (PG) shrinkage and neck volume reduction during radiotherapy of head and neck (H&N) cancer patients is a clinical issue that has prompted interest in adaptive radiotherapy (ART). This study focuses on the difference between planned dose and delivered dose and the possible effects of an efficient replanning strategy during the course of treatment. Six patients with H&N cancer treated by tomotherapy were retrospectively enrolled. Thirty daily dose distributions (DMVCT ) were calculated on pretreatment megavoltage computed tomography (MVCT) scans...
March 12, 2019: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://read.qxmd.com/read/30871863/individual-field-simultaneous-optimization-ifso-in-spot-scanning-proton-therapy-of-head-and-neck-cancers
#9
Aman Anand, Martin Bues, Mauricio E Gamez, Corbin Stefan, Samir H Patel
In order to better spare organs at risk in the head and neck, the application of proton beam therapy is of great interest. In this study we report the clinical utilization of a novel and robust scanning proton beam therapy treatment planning method called Individual Field Simultaneous Optimization (IFSO) that incorporates the advantages of field patching technique integrated with simultaneous optimization of multiple fields. A treatment planning intercomparison between a conventional Intensity Modulated Proton Therapy Treatment Plan with single target volume vs a split target volume utilizing IFSO method demonstrates superiority of IFSO with regards to sparing of organs at risk and plan robustness...
March 12, 2019: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://read.qxmd.com/read/30857654/image-guidance-technique-comparison-on-respiratory-reproducibility-and-dose-indexes-for-stereotactic-body-radiotherapy-in-lung-tumor
#10
Ryuji Kanzaki, Fujio Araki, Shinji Kawamura
We investigated respiratory reproducibility from position errors of gold internal fiducial markers for breath-hold (BH) and real-time tumor tracking (RTT) techniques for stereotactic body radiotherapy in lung tumors. The relationship between position errors and dose indexes was checked for both techniques. The stereotactic body radiotherapy plan in lung tumors was planned for 29 patients. The tumor positioning was arranged using 1.5 mm diameter gold internal fiducial markers. First, CT images were acquired to analyze position errors of gold markers for BH and RTT techniques...
March 8, 2019: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://read.qxmd.com/read/30852064/evaluation-of-the-use-of-abdominal-compression-of-the-lung-in-stereotactic-radiation-therapy
#11
Saba Javadi, Jacob Eckstein, Vincent Ulizio, Russell Palm, Krishna Reddy, David Pearson
The goal of this retrospective study was to determine the benefit in using abdominal compression to reduce tumor motion for patients treated with lung stereotactic body radiotherapy. Forty-four lung lesions (n = 44) from 37 patients (N = 37) treated at the University of Toledo's Dana Cancer Center were assessed by determining the overall tumor displacement along with possible surrogates such as change in tidal volume and diaphragm displacement, with and without abdominal compression. Measurements of lung capacity were acquired from the 4DCT at maximum and minimum respiration in order to determine the tidal volume, with and without abdominal compression...
March 6, 2019: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://read.qxmd.com/read/30846216/radiation-dose-in-the-uterine-perforation-by-tandem-in-3-dimensional-cervical-cancer-brachytherapy
#12
Yu-Lun Tsai, Pei-Chieh Yu, Hsin-Hua Nien, Shih-Yu Sung, Yi-Hsuan Kuan, Ching-Jung Wu
Cervical cancer patients may sometimes experience different types of uterine perforation by a tandem during brachytherapy. The purpose of this study was to address possibly different management strategies regarding different tandem positions from a dosimetry aspect by evaluating radiation doses delivered to organs-at-risk (OAR) in order to help medical professionals handle different types of uterine perforation. Images and dosimetry data in cervical cancer brachytherapy with uterine perforation were reviewed...
March 4, 2019: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://read.qxmd.com/read/30833115/use-of-electronic-portal-images-to-evaluate-setup-error-and-intrafraction-motion-during-free-breathing-breast-imrt-treatment-common-mistake-in-reliability-analysis
#13
LETTER
Seyyed Mohammad Tabatabaei, Meisam Shahsavari
No abstract text is available yet for this article.
March 1, 2019: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://read.qxmd.com/read/30827765/automated-noncoplanar-treatment-planning-strategy-in-stereotactic-radiosurgery-of-multiple-cranial-metastases-hyperarc-and-cyberknife-dose-distributions
#14
Noriyuki Kadoya, Yoshitomo Abe, Tomohiro Kajikawa, Kengo Ito, Takaya Yamamoto, Rei Umezawa, Takahito Chiba, Yoshiyuki Katsuta, Yoshiki Takayama, Takahiro Kato, Yasuhiro Kikuchi, Keiichi Jingu
The purpose of this study was to evaluate and compare the dosimetric effects of HyperArc-based stereotactic radiosurgery (SRS) and a robotic radiosurgery system-based planning using CyberKnife for multiple cranial metastases. In total, 11 cancer patients with multiple cranial metastases (3 to 5 tumors) treated with CyberKnife were examined. These patients were replanned using HyperArc (Varian Medical Systems, Palo Alto, USA). HyperArc plan were designed using 4 noncoplanar arc single-isocenter VMAT in 6 MV flattening filter free mode for simulated delivery with the True beam STx (Varian)...
February 28, 2019: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://read.qxmd.com/read/30799146/performance-evaluation-of-the-x-sight-spine-tracking-system-for-abdominal-tumors-distal-to-spine-a-2d-dosimetric-analysis
#15
Selami Eken, Faruk Zorlu, Mete Yeginer, Gokhan Ozyigit
The X-sight spine tracking system was integrated with Cyberknife unit to deliver radiosurgery treatments for spinal tumors without fiducial placement. However the tracking system can also be used for the treatment of abdominal tumors located in a certain distance from the spine. The aim of our study is to evaluate the tracking performance of the X-sight spine system for abdominal tumors distal to spine based on the 3 factors: tumor distance from the reference vertebra, the angle of tumor with the vertebra, and the amplitude of tumor motion due to respiration...
February 21, 2019: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://read.qxmd.com/read/30738651/monte-carlo-dose-verification-for-a-single-isocenter-vmat-plan-in-multiple-brain-metastases
#16
Kento Hoshida, Fujio Araki, Takeshi Ohno, Hirofumi Tominaga, Kazuki Komatsu, Kentaro Tamura
The purpose of this study was to verify the accuracy of dose calculation algorithms of a treatment planning system for a single-isocenter volumetric modulated arc therapy (VMAT) plan in multiple brain metastases, by comparing the dose distributions of treatment planning system with those of Monte Carlo (MC) simulations. We used a multitarget phantom containing 9 acrylic balls with a diameter of 15.9 mm inside a Lucy phantom measuring 17 × 17 × 17 cm3 . Seven VMAT plans were created using the multitarget phantom: 1 multitarget plan (MTP) and 6 single target plans (STP)...
February 6, 2019: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://read.qxmd.com/read/30713000/dose-evaluation-of-mri-based-synthetic-ct-generated-using-a-machine-learning-method-for-prostate-cancer-radiotherapy
#17
Ghazal Shafai-Erfani, Tonghe Wang, Yang Lei, Sibo Tian, Pretesh Patel, Ashesh B Jani, Walter J Curran, Tian Liu, Xiaofeng Yang
Magnetic resonance imaging (MRI)-only radiotherapy treatment planning is attractive since MRI provides superior soft tissue contrast over computed tomographies (CTs), without the ionizing radiation exposure. However, it requires the generation of a synthetic CT (SCT) from MRIs for patient setup and dose calculation. In this study, we aim to investigate the accuracy of dose calculation in prostate cancer radiotherapy using SCTs generated from MRIs using our learning-based method. We retrospectively investigated a total of 17 treatment plans from 10 patients, each having both planning CTs (pCT) and MRIs acquired before treatment...
January 31, 2019: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://read.qxmd.com/read/30655170/end-to-end-testing-of-automatic-plan-optimization-using-raystation-scripting-for-hypofractionated-multimetastatic-brain-stereotactic-radiosurgery
#18
Eun Young Han, Gwe-Ya Kim, Neal Rebueno, Debra N Yeboa, Tina M Briere
For external beam stereotactic radiosurgery of multiple brain metastatic lesions, it is difficult to select optimal treatment isocenters because the orientation and volume of each planning target volume (PTV) and its proximity to critical structures are unique for each patient. The RayStation treatment planning system offers Python-based scripting to optimize the placement of the treatment isocenter by comparing scenario-based plans. This can improve the plan quality by reducing the dose to the normal brain and increasing planning efficiency...
January 14, 2019: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://read.qxmd.com/read/30642696/evaluation-of-the-correlation-between-prostatic-displacement-and-rectal-deformation-using-the-dice-similarity-coefficient-of-the-rectum
#19
Yoshinori Tanabe, Takayuki Ishida, Hidetoshi Eto, Tatsuhiro Sera, Yuki Emoto
To estimate the relationship between the three-dimensional (3D) displacement error of the prostate and rectal deformation for reduction of deviation between the planned and treatment dose, using multiple acquisition planning CT (MPCT) and the Dice similarity coefficient (DSC) for rectal deformation for treatment of patients with prostate cancer. The 3D displacement error between the pelvic bone and a matching fiducial marker was calculated using MPCT in 24 patients who underwent prostate volumetric-modulated arc therapy for prostate cancer...
January 11, 2019: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://read.qxmd.com/read/30639142/dosimetric-comparison-of-helical-tomotherapy-and-vmat-for-anal-cancer-a-single-institutional-experience
#20
Ian Gleeson, Christopher Rose, Joshua Spurrell
To compare the dosimetric results of helical tomotherapy (HT) and volumetric arc therapy (VMAT) in the treatment of anal cancer. Plans were created for 20 (n = 20) patients treated for anal cancer using HT and 2 arc VMAT. Dosimetric comparison was assessed for doses to targets and organs at risk (small bowel, bladder, external genitalia, and femoral heads). Delivery time and dosimetric verification results were also compared. HT showed a higher V95% for both primary and nodal targets (V95% increase by 0...
January 11, 2019: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
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