Antonio M Calafiore, Ruggero de Paulis, Severino Iesu, Domenico Paparella, Gianni Angelini, Mattia Scognamiglio, Paolo Centofanti, Salvatore Nicolardi, Pierpaolo Chivasso, Carlo Canosa, Salvatore Zaccaria, Luigi de Martino, Diego Magnano, Giuseppe Mastrototaro, Michele Di Mauro
BACKGROUND: Deep hypothermic circulatory arrest (DHCA) at ≤20°C for aortic arch surgery has been widely used for decades, with or without cerebral perfusion (CP), antegrade (antegrade cerebral perfusion [ACP]), or retrograde. In recent years nadir temperature progressively increased to 26°C-28°C (moderately hypothermic circulatory arrest [MHCA]), adding ACP. Aim of this multicentric study is to evaluate early results of aortic arch surgery and if DHCA with 10 min of cold reperfusion at the same nadir temperature of the CA before rewarming (delayed rewarming [DR]) can provide a neuroprotection and a lower body protection similar to that provided by MHCA + ACP...
December 2022: Journal of Cardiac Surgery