Lan Xiong, Guy A Rouleau, Lynn E Delisi, Judith St-Onge, Robert Najafee, Jean-Baptiste Rivière, Chawki Benkelfat, Karim Tabbane, Ferid Fathalli, Zoltan Danics, Alain Labelle, Samarthji Lal, Ridha Joober
The Nogo gene was putatively implicated in schizophrenia based on gene expression and genetic association data. In this study, we attempt to replicate the possible association of the CAA insertion and a nearby TATC deletion with schizophrenia in 204 complete and incomplete triads and in a sample of 462 unrelated cases and 153 controls, all of Caucasian origin. Our genotyping results indicated that neither the trinucleotide insertion polymorphism (CAAins; 43.4% vs. 41.8%, p>0.5) nor the polymorphism-TATC deletion (TATCdel; 49...
January 5, 2005: Brain Research. Molecular Brain Research