Yang Li, Muzhapaer Maimaiti, Bowen Yang, Zeyi Lu, Qiming Zheng, Yudong Lin, Wenqin Luo, Ruyue Wang, Lifeng Ding, Huan Wang, Xianjiong Chen, Zhehao Xu, Mingchao Wang, Gonghui Li, Lei Gao
BACKGROUND: Immune therapy is widely used in treating clear cell renal cell carcinoma (ccRCC), yet identifying patient subgroups that are expected to response remains challenging. As complement system can mediate immune effects, including the progression of tumors, a correlation between complement system and immune therapy may exist. METHODS: Based on 11 complement system associated genes (CSAGs) identified from The Cancer Genome Atlas (TCGA), we performed unsupervised clustering and classified the tumors into two different complement system (CS) patterns...
September 15, 2023: Cellular Signalling