journal
https://read.qxmd.com/read/38358721/an-examination-of-semantic-performance-in-mild-cognitive-impairment-progressors-and-nonprogressors
#1
JOURNAL ARTICLE
Emilie Delage, Isabelle Rouleau, Marc-Antoine Akzam-Ouellette, Frédérique Roy-Côté, Sven Joubert
OBJECTIVE: Mild cognitive impairment (MCI) is a risk factor for developing Alzheimer's disease (AD), and about half of older people with MCI will progress to AD within the next 5 years. The aim of the present study was to compare the semantic performance of MCI progressors (MCI-p) and nonprogressors (MCI-np). The hypothesis was that MCI-p would present with poorer semantic performance relative to MCI-np at baseline, indicating that semantic deficits may increase the risk of future decline toward AD...
February 15, 2024: Neuropsychology
https://read.qxmd.com/read/38330362/cardiovascular-health-and-rate-of-cognitive-decline-in-preclinical-dementia-a-12-year-population-based-study
#2
JOURNAL ARTICLE
Andreja Speh, Nicola Maria Payton, Milica G Kramberger, Giulia Grande, Chengxuan Qiu, Bengt Winblad, Laura Fratiglioni, Lars Bäckman, Erika J Laukka
OBJECTIVE: We investigated whether vascular risk factors (VRFs), assessed with Life's Simple 7 (LS7), are associated with the rate of cognitive decline in the years preceding a dementia diagnosis. METHOD: This study included 1,449 stroke-free participants aged ≥60 years from the Swedish National Study on Aging and Care in Kungsholmen, who underwent repeated neuropsychological testing (episodic memory, semantic memory, verbal fluency, perceptual speed) across 12 years...
February 8, 2024: Neuropsychology
https://read.qxmd.com/read/38330361/language-switching-and-speaking-a-nondominant-language-challenge-executive-control-preliminary-data-for-novel-behavioral-markers-of-alzheimer-s-risk-in-spanish-english-bilinguals
#3
JOURNAL ARTICLE
Dalia L Garcia, Tamar H Gollan
OBJECTIVE: The present study explored psycholinguistic analysis of spoken responses produced in a structured interview and cued linguistic and nonlinguistic task switching as possible novel markers of Alzheimer's disease (AD) risk in Spanish-English bilinguals. METHOD: Nineteen Spanish-English bilinguals completed an Oral Proficiency Interview (OPI) in both languages, cued-switching tasks, and a battery of traditional neuropsychological tests (in a separate testing session)...
February 8, 2024: Neuropsychology
https://read.qxmd.com/read/38330360/association-between-neuropsychological-assessment-and-amyloid-status-in-a-clinical-setting
#4
JOURNAL ARTICLE
Laura E Korthauer, Zachary T Gemelli, Deirdre O'Shea, Brian R Ott, Jennifer D Davis
OBJECTIVE: Large research cohorts show robust associations between neuropsychological tests and Alzheimer's disease (AD) biomarkers, but studies in clinical settings are limited. The increasing availability of AD biomarkers to the practicing clinician makes it important to understand the relationship between comprehensive clinical neuropsychological assessment and biomarker status. This study examined concordance between practicing clinical neuropsychologists' diagnostic impressions and AD biomarker status in patients seen at an outpatient medical center, with a secondary aim of defining the characteristics of discordant cases...
February 8, 2024: Neuropsychology
https://read.qxmd.com/read/38330359/antecedents-of-mind-wandering-states-in-healthy-aging-and-mild-cognitive-impairment
#5
JOURNAL ARTICLE
Andrew J Aschenbrenner, Matthew S Welhaf, Jason J Hassenstab, Joshua J Jackson
OBJECTIVE: Mind wandering refers to periods of internally directed attention and comprises up to 30% or more of our waking thoughts. Frequent mind wandering can be detrimental to ongoing task performance. We aim to determine whether rates of mind wandering change in healthy aging and mild cognitive impairment and how differences in mind wandering contribute to differences in attention and working memory. METHOD: We administered a standard behavioral task, the Sustained Attention to Response Test, to measure mind wandering in healthy younger adults ( N = 66), healthy older adults ( N = 51), and adults with cognitive impairment ( N = 38), that was completed daily for 3 weeks...
February 8, 2024: Neuropsychology
https://read.qxmd.com/read/38330358/processing-speed-in-first-episode-of-psychosis-and-first-degree-relatives-a-candidate-endophenotype-of-spectrum-schizophrenia-disorders
#6
JOURNAL ARTICLE
Ángel Yorca-Ruiz, Nancy Murillo-García, Rebeca Magdaleno Herrero, Alexandre Díaz-Pons, Víctor Ortiz García de la Foz, Luis Manuel Fernández Cacho, Mónica L Fanarraga, Rosa Ayesa-Arriola
OBJECTIVE: The processing speed (PS) is highly impacted in individuals experiencing their first episode of psychosis (FEP). Conducting family studies can help to determine whether PS can serve as an endophenotype of schizophrenia spectrum disorders (SSDs), offering valuable insights into the prevention and diagnosis of SSDs. METHOD: A comprehensive cognitive battery, encompassing tests for PS, verbal memory, visual memory, working memory, executive functions, motor dexterity, and attention, was administered to a sample consisting of 133 FEP patients, 146 parents, 98 siblings, and 202 healthy controls (HCs)...
February 8, 2024: Neuropsychology
https://read.qxmd.com/read/38300582/vulnerability-to-semantic-and-phonological-interference-in-normal-aging-and-amnestic-mild-cognitive-impairment-amci
#7
JOURNAL ARTICLE
Marie-Joëlle Chasles, Sven Joubert, Jessica Cole, Émilie Delage, Isabelle Rouleau
OBJECTIVE: To determine whether the increased vulnerability to semantic interference previously observed in amnestic mild cognitive impairment (aMCI) is specifically associated with semantic material or if it also affects other types of material, suggesting generalized executive and inhibitory impairment. METHOD: Seventy-two participants divided into two groups (33 aMCI, 39 normal control [NC]) matched for age and education were included. They completed a comprehensive neuropsychological examination, the French version of the Loewenstein Acevedo Scale for Semantic Interference and Learning (LASSI-L; semantic interference test), and a homologous experimental phonological test, the phonological interference and learning test...
February 1, 2024: Neuropsychology
https://read.qxmd.com/read/38300581/potential-cognitive-risks-of-generative-transformer-based-ai-chatbots-on-higher-order-executive-functions
#8
JOURNAL ARTICLE
Umberto León-Domínguez
BACKGROUND: Chat generative retrained transformer (ChatGPT) represents a groundbreaking advancement in Artificial Intelligence (AI-chatbot) technology, utilizing transformer algorithms to enhance natural language processing and facilitating their use for addressing specific tasks. These AI chatbots can respond to questions by generating verbal instructions similar to those a person would provide during the problem-solving process. AIM: ChatGPT has become the fastest growing software in terms of user adoption in history, leading to an anticipated widespread use of this technology in the general population...
February 1, 2024: Neuropsychology
https://read.qxmd.com/read/38300580/effect-of-multiple-sclerosis-and-aging-on-prospective-memory-using-the-ecological-test-of-prospective-memory
#9
JOURNAL ARTICLE
Kim Charest, Marie-Julie Potvin, Estefania Brando, Alexandra Tremblay, Élaine Roger, Pierre Duquette, Isabelle Rouleau
OBJECTIVE: Prospective memory (PM) is the ability to remember to produce an action at a specific moment in the future signaled by the occurrence of a specific event (event-based [EB] condition), a time or a time interval (time-based [TB] condition). Detection of the appropriate moment corresponds to the prospective component, while production of the appropriate action corresponds to the retrospective component. Although PM difficulties have been reported in healthy aging and in association with multiple sclerosis (MS), PM has not been examined in older persons with MS (PwMS)...
February 1, 2024: Neuropsychology
https://read.qxmd.com/read/38300579/the-relationship-between-working-memory-and-anxiety-in-individuals-with-early-treated-phenylketonuria-pku
#10
JOURNAL ARTICLE
Kelly M Boland, Meriah S Schoen, Rani H Singh, Hayley E Clocksin, Mackenzie N Cissne, Shawn E Christ
OBJECTIVE: Although early diagnosis and treatment prevent the severe impairments associated with untreated phenylketonuria (PKU), individuals with early treated PKU (ETPKU) nonetheless experience significant neurocognitive and psychological sequelae, including difficulties in working memory (WM) and increased risk of anxiety. The primary objective of the present study was to examine the extent to which anxiety may moderate the relationship between ETPKU and WM performance. METHOD: A sample of 40 adults with ETPKU and a demographically comparable sample of 40 healthy adults without PKU completed a comprehensive assessment of WM performance and anxiety symptomatology...
February 1, 2024: Neuropsychology
https://read.qxmd.com/read/38271061/error-processing-in-young-adulthood-age-related-differences-in-electrophysiology-and-behavioral-performance
#11
JOURNAL ARTICLE
Martina Knežević
OBJECTIVE: The error-related negativity (ERN) and the error positivity (Pe) are electrophysiological components of error processing that develop throughout adolescence and into adulthood. As young people in their early 20s make many important life decisions, the inability to monitor and adapt behavior appropriately may interfere with their personal goals, such as educational or professional achievements. The aim of this study was to investigate age-related differences in error processing across young adulthood...
January 25, 2024: Neuropsychology
https://read.qxmd.com/read/38252108/true-and-false-memory-priming-of-perceptual-closure-problems-in-healthy-older-adults-and-older-adults-with-alzheimer-s-disease
#12
JOURNAL ARTICLE
Mark L Howe, Shazia Akhtar
OBJECTIVE: The present study set out to investigate whether false memories for pictures exhibit priming effects in older adult controls (OACs) and people with early onset Alzheimer's disease (AD). We conducted two studies to examine whether false memories for pictures had a priming effect on a perceptual closure task (PCT). METHOD: In Experiment 1, OACs and people with early onset AD were presented with pictorial versions of the Deese/Rodiger-McDermott lists and took part in a recognition task...
January 22, 2024: Neuropsychology
https://read.qxmd.com/read/38127515/spatial-attention-modulation-of-the-brain-network-involved-in-mental-time-travel
#13
JOURNAL ARTICLE
Claudia Casadio, Ivan Patané, Daniela Ballotta, Michela Candini, Fausta Lui, Francesca Benuzzi, Francesca Frassinetti
OBJECTIVES: The ability to mental time travel (MTT) consists in moving along a cognitive and spatially oriented representation of time, that is, an ideal mental time line, where past and future events are, respectively, located on the left and on the right portion of such a line. A shift of spatial attention by prismatic adaptation (PA) influences this spatial coding of time, thus affecting MTT. Here, we investigated the neural correlates of such a spatial modulation on MTT in a functional Magnetic Resonance Imaging protocol...
December 21, 2023: Neuropsychology
https://read.qxmd.com/read/38095938/the-relationship-between-social-cognitive-processes-and-behavior-changes-in-people-with-amnestic-mild-cognitive-impairment-or-dementia-using-the-edinburgh-social-cognition-test-escot
#14
JOURNAL ARTICLE
R Asaad Baksh, Sarah E MacPherson, Bonnie Auyeung, Suvankar Pal, Sharon Abrahams
OBJECTIVE: People with amnestic mild cognitive impairment (aMCI) or dementia often exhibit a decline in their social abilities, but few tests of social cognition exist that are suitable for clinical use. Moreover, the relationship between changes in behavior and impairments in social cognition is poorly understood. We examined the utility of the Edinburgh Social Cognition Test (ESCoT) in people with aMCI/dementia and explored associations between social cognition performance and behavior changes...
December 14, 2023: Neuropsychology
https://read.qxmd.com/read/37971862/capturing-learning-curves-with-the-multiday-boston-remote-assessment-of-neurocognitive-health-branch-feasibility-reliability-and-validity
#15
JOURNAL ARTICLE
Emma L Weizenbaum, Daniel Soberanes, Stephanie Hsieh, Cassidy P Molinare, Rachel F Buckley, Rebecca A Betensky, Michael J Properzi, Gad A Marshall, Dorene M Rentz, Keith A Johnson, Reisa A Sperling, Rebecca E Amariglio, Kathryn V Papp
OBJECTIVE: Unsupervised remote digital cognitive assessment makes frequent testing feasible and allows for measurement of learning over repeated evaluations on participants' own devices. This provides the opportunity to derive individual multiday learning curve scores over short intervals. Here, we report feasibility, reliability, and validity, of a 7-day cognitive battery from the Boston Remote Assessment for Neurocognitive Health (Multiday BRANCH), an unsupervised web-based assessment...
November 16, 2023: Neuropsychology
https://read.qxmd.com/read/37971861/increased-intraindividual-variability-in-reaction-time-performance-is-associated-with-emerging-cognitive-decline-in-cognitively-unimpaired-adults
#16
JOURNAL ARTICLE
Roos J Jutten, Rebecca E Amariglio, Paul Maruff, Michael J Properzi, Dorene M Rentz, Keith A Johnson, Reisa A Sperling, Kathryn V Papp
OBJECTIVE: To investigate whether intraindividual variability (IIV) in reaction time (RT) over monthly administered cognitive tasks is increased in cognitively unimpaired older adults who are at risk for cognitive decline, and whether this is independent of mean RT performance. METHOD: N = 109 cognitively unimpaired individuals (age 77.4 ± 5.0, 61.5% female, Mini-Mental State Examination 29.1 ± 1.3) from the Harvard Aging Brain Study completed the self-administered Computerized Cognitive Composite (C3) monthly at home for up to 1 year (12...
November 16, 2023: Neuropsychology
https://read.qxmd.com/read/37971860/identifying-and-distinguishing-cognitive-profiles-among-virally-suppressed-people-with-hiv
#17
JOURNAL ARTICLE
Erin E Sundermann, Raha Dastgheyb, David J Moore, Alison S Buchholz, Mark W Bondi, Ronald J Ellis, Scott L Letendre, Robert K Heaton, Leah H Rubin
OBJECTIVE: Cognitive deficits are common among people with HIV (PWH), even when virally suppressed. We identified cognitive profiles among virally suppressed PWH and determined how sociodemographic, clinical/behavioral, and HIV disease characteristics distinguish profile membership. METHOD: Participants included 704 virally suppressed PWH ( M age = 43.9 [ SD = 10.2], 88% male, 58.9% non-Hispanic White) from the HIV Neurobehavioral Research Program. Demographically adjusted T scores were derived from a neuropsychological evaluation comprised of 13 tests...
November 16, 2023: Neuropsychology
https://read.qxmd.com/read/37971859/a-diffusion-decision-model-analysis-of-the-cognitive-effects-of-neurofeedback-for-adhd
#18
JOURNAL ARTICLE
Nadja R Ging-Jehli, Quinn A Painter, Helena A Kraemer, Michelle E Roley-Roberts, Catherine Panchyshyn, Roger deBeus, L Eugene Arnold
OBJECTIVE: To examine cognitive effects of neurofeedback (NF) for attention-deficit hyperactivity disorder (ADHD) as a secondary outcome of a randomized clinical trial. METHOD: In a double-blind randomized clinical trial (NCT02251743), 133 7-10-year olds with ADHD received either 38 sessions of NF ( n = 78) or control treatment ( n = 55) and performed an integrated visual and auditory continuous performance test at baseline, mid- and end-treatment. We used the diffusion decision model to decompose integrated visual and auditory continuous performance test performance at each assessment into cognitive components: efficiency of integrating stimulus information ( v ), context sensitivity ( cv ), response cautiousness ( a ), response bias ( z/a ), and nondecision time for perceptual encoding and response execution ( Ter )...
November 16, 2023: Neuropsychology
https://read.qxmd.com/read/37971858/does-early-adversity-predict-executive-functioning-difficulties-among-undergraduates-dissociations-among-self-report-performance-and-eeg-measures
#19
JOURNAL ARTICLE
Rebecca J Compton, Eric Kopczynski, Keishla Sanchez, Katrina Severtson, Joanna Gengo, Olivia Ahart, Lauren Handler
OBJECTIVE: The present research aimed to determine whether self-reports of early adversity predicted individual differences in self-reported and laboratory-measured executive functioning in college-aged samples. METHOD: Two studies with young adult samples ( n = 231 and n = 61) measured endorsement of adverse childhood experiences (ACEs), self-reported executive functioning difficulties on the Behavior Rating Inventory of Executive Function (BRIEF), and self-report measures of depression and emotion regulation...
November 16, 2023: Neuropsychology
https://read.qxmd.com/read/37917438/catastrophizing-is-associated-with-excess-cognitive-symptom-reporting-after-mild-traumatic-brain-injury
#20
JOURNAL ARTICLE
Shuyuan Shi, Edwina L Picon, Mathilde Rioux, William J Panenka, Noah D Silverberg
OBJECTIVE: Persistent cognitive symptoms after mild traumatic brain injury (mTBI) often do not correlate with objective neuropsychological performance. Catastrophizing (i.e., excessively negative interpretations of symptoms) may help explain this discrepancy. We hypothesize that symptom catastrophizing will be associated with greater cognitive symptom reporting relative to neuropsychological test performance in people seeking treatment for mTBI. METHOD: Secondary analysis of baseline data from a randomized controlled trial...
November 2, 2023: Neuropsychology
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