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Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre

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https://read.qxmd.com/read/30763943/diversity-of-nontuberculous-mycobacteria-in-kuwait-rapid-identification-and-differentiation-of-mycobacterium-species-by-multiplex-pcr-inno-lipa-mycobacteria-v2-assay-and-pcr-sequencing-of-rdna
#1
Suhail Ahmad, Eiman Mokaddas
OBJECTIVE: Nontuberculous mycobacteria (NTM) often cause disease that is clinically indistinguishable from tuberculosis. Specific identification is important as treatment varies according to Mycobacterium species causing the infection. This study used multiplex PCR (mPCR) assay for rapid differentiation of mycobacterial growth indicator tube 960 system (MGIT) cultures as Mycobacterium tuberculosis (MTB) or NTM together with INNO LiPA Mycobacteria v2 assay (LiPA) and/or PCR-sequencing of rDNA for species-specific identification of selected MTB and all NTM isolates in Kuwait...
February 14, 2019: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://read.qxmd.com/read/30763942/whipple-s-disease-a-case-report
#2
Orkide Kutlu, Selma Şengiz Erhan, Yasemin Gökden, Özlem Kandemir, Tufan Tükek
Objective<br><br>Whipple's disease is a very rare systemic infectious disease, with an incidence of 1 in one million, which may be fatal if not diagnosed and treated appropriately. <br><br>Clinical Presentation and Intervention<br><br>Herein we will describe a 49 years old male patient admitted to the hospital with the signs of severe malabsorption and diagnosed with Whipple's disease. <br><br>Conclusion<br><br>We aimed to emphasize the Whipple's disease to be kept in mind for the prompt diagnosis and treatment of patients with malabsorption...
February 14, 2019: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://read.qxmd.com/read/30739108/thyroid-ultrasound-reports-deficiencies-and-recommendations
#3
Laila Qadan, Adel Ahmed, Kusum Kapila
OBJECTIVE: Thyroid ultrasound plays a major role in the clinical management of patients with thyroid nodules. Comprehensive reporting enables malignant risk stratification and biopsy decisions. In this study, we aimed at a systematic evaluation of the content and completeness of thyroid radiology reports. METHODS: A retrospective study was undertaken. A total of 200 thyroid ultrasound reports of examinations performed over a year period were reviewed. After excluding 18 reports, the remaining 182 were evaluated for the inclusion of the following nodule characteristics: size, 3- axis dimensions, location, presence or absence of five signs suspicious of malignancy namely, micro calcification, hypoechogenecity, irregular margin, height to width ratio and intranodular vascularity...
February 10, 2019: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://read.qxmd.com/read/30739104/association-between-peripheral-artery-disease-and-major-adverse-cardiovascular-events-in-patients-with-acute-coronary-syndrome-findings-from-the-gulf-coast-registry
#4
Ibrahim Al-Zakwani, Ekram Al-Siyabi, Najib Alrawahi, Arif AlMulla, Abdullah Alnaeemi, Abdulla Shehab, Mohammed Zubaid
OBJECTIVE: To evaluate the association between peripheral artery disease (PAD) and major adverse cardiovascular events (MACE) in patients with acute coronary syndrome (ACS) in the Arabian Gulf. METHODS: Data was analyzed from 4044 consecutive patients diagnosed with ACS admitted to 29 hospitals in four Arabian Gulf countries from January 2012 to January 2013. PAD was defined as any of the following: claudication, amputation for arterial vascular insufficiency, vascular reconstruction, bypass surgery, or percutaneous intervention in the extremities, documented aortic aneurysm or ankle brachial index of < 0...
February 10, 2019: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://read.qxmd.com/read/30731465/age-specific-reference-ranges-of-prostate-specific-antigen-among-saudi-men-as-a-representation-of-the-arab-population
#5
Danny Rabah, Karim Farhat, Mohamed Al-Atawi, Mostafa Arafa
OBJECTIVE: To describe the reference ranges of serum prostate-specific antigen (PSA) in Saudi men. Materials/Subjects and Methods: Saudi males, aged 30 and above, were invited to participate in the study. Blood samples were taken from each subject to determine serum levels of PSA. Blood sugar levels, lipid profile and anthropometric measurements were also obtained. RESULTS: Our cohort consisted of 7814 men; their mean PSA level was 1.24 ng/ml. The majority (90.5%) had PSA values between 0 and 2...
February 7, 2019: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://read.qxmd.com/read/30726858/galectin-3-in-acute-myocardial-infarction-patients-with-atrial-fibrillation
#6
Dragana Stanojevic, Svetlana R Apostolovic, Dragana Stokanovic, Stefan Momcilovic, Tatjana Jevtovic-Stoimenov, Valentina Nikolic, Sonja Salinger-Martinovic, Tomislav Kostic
OBJECTIVE: Atrial fibrillation (AF) is common in acute myocardial infarction (AMI), and galectin-3 is possibly involved in its occurrence. Galectin-3 has been shown to play a central role in fibrosis and tissue remodeling and has a role in inflammatory and proliferative responses. The aim of our study was to measure galectin-3 levels in patients with myocardial infarction and to compare its levels in patients with or without AF, in order to investigate the potential predictive role of galectin-3 in this setting...
February 6, 2019: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://read.qxmd.com/read/30726857/comparison-of-subjective-and-objective-assessments-of-neurosensory-function-after-lingual-nerve-repair
#7
Yukari Shintani, Takashi Nakanishi, Masamichi Ueda, Naoki Mizobata, Itaru Tojyo, Shigeyuki Fujita
OBJECTIVE: Mandibular third molar extractions are important in oral maxillofacial surgery. Damage to the lingual nerves, although rare, is a possible complication. There are reports of postoperative recovery after lingual nerve repair, but few reports compared subjective and objective assessments of neurosensory function. Therefore, this study aims to compare subjective and objective assessments of neurosensory function after lingual nerve repair. SUBJECTS AND METHODS: This retrospective cohort study comprised 52 patients with lingual nerve anesthesia after third molar extraction at the Department of Oral and Maxillofacial Surgery, Wakayama Medical University Hospital between December 2008 and December 2015...
February 6, 2019: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://read.qxmd.com/read/30726852/pigment-epithelium-derived-factor-affects-angiogenesis-in-celiac-disease
#8
Muhammet Akpinar, Evrim Kahramanoğlu Aksoy, Ferdane Pirinçci Sapmaz, Ozlem Ceylan Dogan, Metin Kucukazman, Yaşar Nazlıgul
OBJECTIVE: Recent studies have demonstrated that angiogenesis is impaired in patients with celiac disease (CD). In this study, we evaluated the levels of the novel anti-angiogenic factor pigment epithelium-derived factor (PEDF) in CD patients. METHODS: 84 patients were included in the study; 71 patients with celiac disease and 13 healthy controls. In the CD patient cohort, there were 21 newly diagnosed patients, 19 with adherence to a gluten-free diet and 31 practiced no adherence to this diet...
February 6, 2019: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://read.qxmd.com/read/30716739/glomerular-filtration-rate-as-a-prognostic-factor-for-long-term-mortality-after-acute-pulmonary-embolism
#9
Valdis Gibietis, Dana Kigitovica, Barbara Vitola, Sintija Strautmane, Andris Skride
<br>To determine the impact of estimated glomerular filtration rate (eGFR) and creatinine clearance (CrCl) on long-term all-cause mortality following acute PE in association with other routine laboratory analyses and comorbidities.<br> Materials (Subjects) and Methods<br>The prospective study enrolled 141 consecutive patients presenting with objectively confirmed acute PE. Demographic, clinical data, comorbidities and laboratory values were recorded. CrCl and GFR was estimated using Cockcroft-Gault, MDRD and CKD-EPI equations...
February 4, 2019: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://read.qxmd.com/read/30716736/orthodontically-relevant-manifestations-in-people-with-rare-diseases
#10
Marcel Hanisch, Lale Hanisch, Johannes Kleinheinz, Gholamreza Danesh, Korbinian Benz, Joachim Jackowski
BACKGROUND: Approximately 15% of all rare diseases occur with orofacial manifestations. Symptoms and manifestations of relevance to orthodontists represent a considerable proportion of these diseases and require appropriate strategies for their treatment. This article provides an overview of the orthodontically-relevant manifestations of rare diseases. MATERIAL AND METHODS: Overall, 3639 rare diseases listed at the Orphanet, OMIM or Pubmed database were evaluated for orofacial manifestations...
February 4, 2019: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://read.qxmd.com/read/30712035/abstracts-of-award-winning-posters-23rd-annual-health-sciences-poster-conference-faculty-of-medicine-health-sciences-centre-kuwait-university-kuwait-march-13-15-2018
#11
(no author information available yet)
No abstract text is available yet for this article.
February 1, 2019: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://read.qxmd.com/read/30703772/attitudes-of-physicians-towards-different-types-of-euthanasia-in-kuwait
#12
Shaikhah Abohaimed, Basma Matar, Hussain Al-Shimali, Khalid Althalji, Omar Alothman, Yasmin Zurba, Nasra Shah
OBJECTIVE: Although in recent years the world has witnessed great advances in the medical field, much ambiguity still surrounds the issue of euthanasia and physician-assisted suicide, with increasingly favorable attitudes amongst physicians around the world. In our study, we aimed to assess the attitudes of physicians in Kuwait towards different types of euthanasia, and to examine whether physicians' frequent encounters with terminally-ill patients were associated with their approval...
January 31, 2019: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://read.qxmd.com/read/30685765/precision-diabetes-is-slowly-becoming-a-reality
#13
REVIEW
V Mohan, Venkatesan Radha
The concept of precision medicine is becoming increasingly popular. The use of big data, genomics and other 'omics' like metabolomics, proteomics and trancriptomics could make the dream of personalized medicine become a reality in the near future. As far as polygenic forms of diabetes like type 2 diabetes (T2DM) and type 1 diabetes (T1DM) are concerned, interesting leads are emerging, but precision diabetes is still in its infancy. However, with regard to monogenic forms of diabetes like Maturity-Onset-diabetes of the young (MODY) and Neonatal Diabetes Mellitus (NDM), rapid strides have been made and precision diabetes has already become part of the clinical tools used at advanced diabetes centres...
January 27, 2019: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://read.qxmd.com/read/30685759/maternal-haematological-parameters-and-placental-and-umbilical-cord-histopathology-in-intrauterine-growth-restriction
#14
Mária Jakó, Andrea Surányi, László Kaizer, Gábor Németh, György Bártfai
<br><br>There are literature data on the relationship between pregnancy outcomes and placental morphology, ultrasonic fetal biometry and arterial Doppler flow velocimetry in relation to placental morphometry We investigated the placental and umbilical cord histopathology in IUGR, and their relation with second trimester maternal haematological parameters.<br><br>Materials (Subjects) and Methods<br><br>Women were followed up with ultraonography and blood samples were taken between the 20-24th gestational weeks and they were selected for IUGR group based on estimated fetal weight below the 10th percentile...
January 27, 2019: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://read.qxmd.com/read/30677775/a-rare-variant-of-the-great-cardiac-vein-draining-directly-into-the-superior-vena-cava
#15
Ecaterina Dăescu, Alexandra Enache, Dorina Sztika, Delia Zahoi
OBJECTIVE: A routine dissection of a 67-year-old cadaver revealed a very rare morphological variant of the great cardiac vein. PRESENTATION: The vein originated in the upper third of the anterior interventricular sulcus, crossed the anterior interventricular artery superficially, ran beneath the circumflex artery, crossed the transverse pericardial sinus and drained directly into the superior vena cava (SVC). CONCLUSION: This variant of the great cardiac vein is interesting due to its rarity, and is important for procedures that require venous access such as coronary surgery requiring retrograde cardioplegia, surgical ablation of aberrant conducting pathways, pacemaker insertion and valve surgery...
January 24, 2019: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://read.qxmd.com/read/30650407/probable-etoricoxib-induced-severe-thrombocytopenia-a-case-report
#16
Guerino Recinella, Alessandro De Marchi, Enrico Pirazzoli, Giampaolo Bianchi
OBJECTIVE: To describe a case of likely etoricoxib-induced severe thrombocytopenia. CLINICAL PRESENTATION AND INTERVENTION: A 32-year-old woman was referred to our hospital for disseminated petechial rash after seven days of therapy with etoricoxib. At admission, the patient's platelet count was 3000/mmc. At Naranjo's scale correlation between thrombocytopenia and drug was considered as "probable". With the diagnostic tests performed we did not find other causes of thrombocytopenia...
January 16, 2019: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://read.qxmd.com/read/30646003/the-effectiveness-of-different-doses-of-intravenous-immunoglobulin-on-severe-hand-foot-and-mouth-disease-a-meta-analysis
#17
Wei Jiao, Si-Ran Tan, Yan-Feng Huang, Lihong Mu, Yang Yang, Yan Wang, Xue-E Wu
OBJECTIVE: To conduct a meta-analysis of evidence from randomized controlled trails (RCTs) of different doses of Intravenous Immunoglobulin (IVIG) in children with severe hand, foot and mouth disease (HFMD) to provide the scientific basis for clinical practice. METHODS: A search of PubMed-Medline, CNKI, Wanfang, and VIP database (until 30 June 2017) was performed and Software RevMan5.3 was used to evaluate the effect of different doses of IVIG on HFMD in RCTs, We used random effects models (or fixed effects models) and generic inverse variance methods to process quantitative data, followed by a leave-one-out method for sensitivity analysis...
January 15, 2019: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://read.qxmd.com/read/30636243/a-pilot-study-urinary-uromodulin-creatinine-ratio-as-a-potential-clinical-biomarker-for-ckd-patients-with-gout
#18
Chien-Hsing Wu, Chih-Chao Yang, Hsueh-Wen Chang, Bin Huang, Chung-Jen Chen, Eton I-Cheng Lin, Chien-Yi Wu, Yueh-Hua Chung, Yu-Han Hsu, Chien-Te Lee, Feng-Rong Chuang
OBJECTIVE: Recent studies have reported that reduced excretion of urinary uromodulin (uUMOD) was associated with renal tubular function and risks of progressive kidney disease. Gouty nephropathy is usually seen in patients with gout. Patients with chronic gouty nephropathy are characterized by the deposition of monosodium urate crystals primarily involving the collecting ducts in the medulla. We postulated that this correlation may be specific to gout, and may serve as a useful biomarker for CKD...
January 13, 2019: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://read.qxmd.com/read/30583293/a-meta-analysis-on-the-relationship-between-hair-dye-and-the-incidence-of-non-hodgkin-s-lymphoma
#19
Ling Qin, Hui-Yang Deng, Sheng-Jiang Chen, Wei Wei
BACKGROUND: Epidemiologic studies have suggested hair dye to be a risk factor for many cancers. However, previous studies on the association between the personal use of hair dye and risk of non-Hodgkin's lymphoma (NHL) have been inconclusive. METHODS: Pubmed, Embase, Cochrane Library and Web of Science databases, as well as the references cited in included studies, were searched for relevant studies up to February 10, 2015. Odds ratios (ORs) with 95% confidence intervals (CIs) were applied to assess the strength of the association...
December 24, 2018: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://read.qxmd.com/read/30566950/a-case-of-massive-cerebral-arterial-air-embolism-induced-by-artificial-pneumothorax-and-its-analysis
#20
Xiao-Hua Gou, Wei Yang, Yan-Li Zhang, Ya Li, Xin Wu
OBJECTIVE: This study aimed to investigate the characteristics of cerebral arterial air embolism. CLINICAL PRESENTATION AND INTERVENTION: The clinical data of a patient with cerebral arterial air embolism induced during artificial pneumothorax was retrospectively analyzed. The patient needed the induction of artificial pneumothorax for medical thoracoscopy, but developed hemiplegia and disturbance of consciousness during the induction, and cerebral arterial air embolism was detected by head computed tomography...
December 19, 2018: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
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