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Journal of Biomaterials Applications | Page 2

Liang Chen, Hanan Mazeh, Angelica Guardia, Wei Song, Paul Begeman, David C Markel, Weiping Ren
No abstract text is available yet for this article.
June 20, 2019: Journal of Biomaterials Applications
Pingping Hu, Dong Fang, Liping Shen, Huangao Zhou, Rui Shao, Miao Chen, Chenghu Yao, Yang Shi, Qian Chen
No abstract text is available yet for this article.
June 13, 2019: Journal of Biomaterials Applications
Lang Lei, Xin Tao, Lifeng Xie, Zhengdong Hong
No abstract text is available yet for this article.
June 13, 2019: Journal of Biomaterials Applications
(no author information available yet)
No abstract text is available yet for this article.
June 11, 2019: Journal of Biomaterials Applications
Kavoos Razmjooee, Saeed Saber-Samandari, Hamid Keshvari, Sara Ahmadi
To improve anti thrombogenicity of polycaprolactone, nanofibrous mat of this synthetic polymer is prepared by electrospinning method. Subsequently, plain electrospun nanofibrous polycaprolactone was treated by RF oxygen plasma to initiate the graft copolymerization with acrylamide monomers. The surface morphology and average fiber diameter of plain electrospun nanofibrous polycaprolactone were determined by scanning electron microscopy technique. The chemical composition and surface characteristics of the samples were examined by static contact angle measurements, and attenuated total reflectance Fourier transfer infrared (ATR-FTIR) spectroscopy...
June 10, 2019: Journal of Biomaterials Applications
Aysun Kılıç Süloğlu, Elif Karacaoğlu, Hayriye Akel Bilgic, Güldeniz Selmanoğlu, Evrim A Koçkaya, Cagatay Karaaslan
Natural and synthetic biomaterials have been designed to aid in the bone regeneration process. Although multiple stem cell-based biomaterials are currently studied by many researchers, no biomaterial has yet been approved as the most appropriate. Here, we aimed to use and compare alternative synthetic biphasic ceramic Ceraform® (CR) coated with the tissue adhesives fibrin glue (FG) and fibronectin (FN) seeded with osteogenically induced cells, which were previously differentiated from adipose tissue-derived mesenchymal cells...
June 5, 2019: Journal of Biomaterials Applications
Weerachai Singhatanadgit, Piyarat Sungkhaphan, Tharinee Theerathanagorn, Somying Patntirapong, Wanida Janvikul
Although attempts have been made to immobilize dual short peptides on a biomaterial surface, the optimization, characterization and functional analysis of the peptide immobilization onto poly(buthylene succinate)/β-tricalcium phosphate (PBSu/TCP) composites have not yet been reported. The present study was, therefore, carried out to optimize and characterize the dual immobilization of type I collagen short peptide (COLsp) and bone morphogenetic protein-2 short peptide (BMP-2sp) onto hydrolyzed PBSu/TCP (HPBSu/TCP) composites, and the bioactivity of the resulting dual peptide-immobilized surfaces was also determined in vitro...
May 28, 2019: Journal of Biomaterials Applications
Wei Zhang, Yu Xin, Bin Yin, Guan L Ye, Jun X Wang, Jian F Shen, Lei Li, Qi H Yang
Carboxymethyl chitosan has the potential to be used in the field of hemostatic materials, but its low molecular weight and high water solubility limit its application. This study prepared crosslinked carboxymethyl chitosan by crosslinking reaction with glutaraldehyde and determined its physicochemical properties, FT-IR spectra, and toxicity and cell morphology on L929 fibroblasts. The hemostatic effect and healing function of crosslinked carboxymethyl chitosan on rat liver were also evaluated. The animals were divided into three groups ( n = 18): control group (Con), Surgicel® group (Sur), and crosslinked carboxymethyl chitosan group (C-CMC)...
May 28, 2019: Journal of Biomaterials Applications
Jong-Keun Kim, Jae-Young Park, Do Weon Lee, Du Hyun Ro, Myung Chul Lee, Hyuk-Soo Han
A temperature sensitive anti-adhesive poloxamer (TAP) hydrogel has been developed to reduce post-operative adhesion. The purpose of this study was to evaluate the efficacy and safety of TAP hydrogel on fascial adhesion and clinical outcomes including range of motion, pain, and patient satisfaction after total knee arthroplasty. Sixty patients who underwent unilateral primary total knee arthroplasty for knee osteoarthritis were included and randomized to either TAP group or control group. After capsular closure, TAP hydrogel was applied on the fascial layer in 30 patients of the TAP hydrogel group, while normal saline was applied to 30 patients of the control group...
May 24, 2019: Journal of Biomaterials Applications
Qingxi Hu, Chuang Wu, Haiguang Zhang
Electrospinning is promising approach for producing biomimetic vascular scaffolds. In particular, gelatin-based electrospun scaffolds offer excellent biocompatibility. However, gelatin-based vascular scaffolds are difficult to remove from the collector after electrospinning and cross-linking agents such as glutaraldehyde, which is commonly used to improve the strength of water-soluble electrospun gelatin, are highly toxic. Herein, we present a novel electrospinning method for preparing three-layered vascular scaffolds...
May 24, 2019: Journal of Biomaterials Applications
Sakshi Jain, R Scott Williamson, Amol V Janorkar, Jason A Griggs, Michael D Roach
Titanium surface modification by anodization has been shown to promote bone formation. However, interactions between anodized layers and bone cells depend upon the anodized layer surface composition and morphology. The present study evaluated the effect of anodized layer phosphorus content, crystallinity, surface porosity, and roughness on the MC3T3-E1 osteoblast response. Commercially pure titanium specimens were anodized in two mixed-acid electrolytes to final forming voltages of 108 V and 180 V. The oxide crystallinity, surface porosity, surface roughness, and elemental composition of each specimen type were determined by X-ray diffraction, scanning electron microscopy, atomic force microscopy, and energy dispersive spectroscopy analyses...
May 24, 2019: Journal of Biomaterials Applications
Xin Zhang, Jian Wang, Jiaxin Wu, Xiaoge Jiang, Xibo Pei, Junyu Chen, Qianbing Wan, Chao Huang
Nanoscale zeolitic imidazolate framework-8 coating with certain density can significantly improve the osteogenic activity of titanium implants both in vitro and in vivo. In this study, we loaded dimethyloxalylglycine into zeolitic imidazolate framework-8-modified implants (Z-AHT) to enhance the angiogenic activity, and the obtained products were denoted as D-AHT. Firstly, we characterized the specimens via scanning electron microscopy, Fourier transform infrared spectroscopy, powder X-ray diffraction, and surface contact angle...
May 22, 2019: Journal of Biomaterials Applications
Rose Ann Gabriel Franco, Andrew R Padalhin, John Patrick Cuenca, Reiza Ventura, Andrew Montecillo, Lilia Fernando, Byong-Taek Lee
Two nanocellulose-producing bacteria were isolated from separate local nata starter cultures and were characterized to determine their putative identity. The nanocellulose produced by the two bacterial isolates were compared to determine if differences between material properties and in vitro biocompatibility were species-dependent. Nanocellulose membranes were produced by inoculating the bacterial isolates to Hestrin-Schramm media using different carbon sources (glucose, mannitol and sucrose). The material properties of nanocellulose membranes were characterized using scanning electron microscopy, Fourier-transform infrared spectroscopy, X-ray dispersive spectroscopy, Calcofluor staining and water retention...
May 22, 2019: Journal of Biomaterials Applications
Nan Zheng, Dan Xie, Zhiyi Zhang, Jia Kuang, Yubin Zheng, Qing Wang, Yang Li
The irreversible correlation between the transfection efficiency and cytotoxicity of polycations has always been the huge obstacle that severely limited the gene delivery efficiency. The undesired inconsistency could be mainly attributed to the molecular weight (MW) of the polycations, that is, polymers with high MW and positive charge densities exhibited enhanced transfection efficiency but with associated cytotoxicity. To address such critical challenge, we developed the degradable high MW polymers strategy which could condense DNA for the internalization and release DNA upon the trigger-responsive degradation...
May 20, 2019: Journal of Biomaterials Applications
Ming Ding, Kariatta Esther Koroma, Jesper Roed Sorensen, Monica Sandri, Anna Tampieri, Stig M Jespersen, Søren Overgaard
The effects of a large collagen-hydroxyapatite (COL-HA) substitute with or without isolated bone marrow nuclear cells (BMNC) on spine fusion were evaluated using a two-level posterolateral spinal fusion model in sheep. Six sheep each were included in both the COL-HA and autograft groups. In each animal, spine fusions were performed at two levels by randomization with or without BMNC. After an observation period of 4.5 months, the fusion blocks (length = 50 mm) were harvested and evaluated by micro-CT with respect to fusion rate and microarchitecture, and histology was performed to qualitatively assess new bone morphology...
May 20, 2019: Journal of Biomaterials Applications
Kai Wei, Jiaming Zhang, Xun Li, Pengfei Shi, Peng Fu
Satisfactory chemotherapy of breast cancer remains to be a great challenge in both experimental and clinical practice. Here in our study, we successfully developed a mixed drug delivery system composed of high density lipoprotein and calcium carbonate nanoparticles. The well-defined calcium carbonate nanoparticles served as a skeleton material to load anticancer drug doxorubicin, while high density lipoprotein served as a coating material to increase the stability and biocompatibility of the as-prepared mixed drug delivery system...
May 20, 2019: Journal of Biomaterials Applications
Peng He, Hong Yan, Junning Zhao, Maling Gou, Xiaolu Li
Wound healing refers to the healing process of skin and other tissues appear to be broken or defective after one body suffers external force. Accelerating wound healing through the use of natural products isolated from plants and microbes is a hot research topic. Tetrahydrocurcumin is one of the major in vivo colorless hydrogenated metabolites of curcumin with superior wound healing and anti-inflammatory properties. The poor bioavailability of these curcuminoids limits their clinical applications. Preparation of curcuminoids-loaded nanoparticles is one appropriate method of addressing this issue...
May 19, 2019: Journal of Biomaterials Applications
(no author information available yet)
No abstract text is available yet for this article.
May 15, 2019: Journal of Biomaterials Applications
Houman Jalaie, Julia Steitz, Mamdouh Afify, Mohammad Esmaeil Barbati, Konrad Hoeft, Mona Ali Mahmoud Assar, Benita Hermanns-Sachweh, Rene H Tolba, Michael J Jacobs, Karina Schleimer
The aim of this study was to compare two variants of a novel polycarbonate polyurethane prosthesis with polyethylene terephthalate (Dacron) prosthesis in an established sheep model of carotid patch angioplasty. Two variants of the polycarbonate polyurethane prosthesis were used: (1) Polycarbonate polyurethane equal (PCU-e) prosthesis consisted of a multilayered porous structure with equal internal and external layers; (2) Polycarbonate polyurethane with more porous inner layers (PCU-mp) prosthesis had more porous inner layers than external layers...
May 14, 2019: Journal of Biomaterials Applications
Haibo Xiang, Yu Wang, Hong Chang, Shenyu Yang, Mei Tu, Xianrong Zhang, Bin Yu
Bone substitute offers a promising strategy for the reconstruction of large bone defects. It may be feasible to develop a better substitute material by enhancing the osteoinductivity and delaying the degradation of α-calcium sulfate hemihydrate. In this study, nano cerium oxide was incorporated with α-calcium sulfate hemihydrate at weight ratios of 5 and 10% to form nano cerium oxide-containing α-calcium sulfate hemihydrate. Extracts from α-calcium sulfate hemihydrate, 5 and 10% nano cerium oxide-containing α-calcium sulfate hemihydrate were prepared for in vitro treatment of cells...
May 14, 2019: Journal of Biomaterials Applications
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